2024-03-29 09:54:15, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001119 3970 bp mRNA linear PRI 01-JUL-2013 DEFINITION Homo sapiens adducin 1 (alpha) (ADD1), transcript variant 1, mRNA. ACCESSION NM_001119 VERSION NM_001119.4 GI:346644753 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 3970) AUTHORS Lin,T.H., Chiu,H.C., Wang,C.L., Hsu,P.C., Su,H.M., Voon,W.C., Lai,W.T. and Sheu,S.H. TITLE The Gly460Trp polymorphism of alpha-adducin gene as a predictor of renal function decline over 4 years of follow-up in an apparently healthy Chinese population JOURNAL Transl Res 160 (2), 162-163 (2012) PUBMED 22677360 REMARK GeneRIF: The alpha-adducin Gly460Trp gene polymorphism might modulate renal function decline in the Chinese. REFERENCE 2 (bases 1 to 3970) AUTHORS Wang,L., Chen,S., Zhao,Q., Hixson,J.E., Rao,D.C., Jaquish,C.E., Huang,J., Lu,X., Chen,J., Cao,J., Li,J., Li,H., He,J., Liu,D.P. and Gu,D. CONSRTM GenSalt Collaborative Research Group TITLE Association between genetic variants of the ADD1 and GNB3 genes and blood pressure response to the cold pressor test in a Chinese Han population: the GenSalt Study JOURNAL Hypertens. Res. 35 (8), 805-810 (2012) PUBMED 22476228 REMARK GeneRIF: genetic variants of the ADD1 and GNB3 genes may have important roles in blood pressure response to the cold pressor test REFERENCE 3 (bases 1 to 3970) AUTHORS Vukojevic,V., Gschwind,L., Vogler,C., Demougin,P., de Quervain,D.J., Papassotiropoulos,A. and Stetak,A. TITLE A role for alpha-adducin (ADD-1) in nematode and human memory JOURNAL EMBO J. 31 (6), 1453-1466 (2012) PUBMED 22307086 REMARK GeneRIF: Findings support a role for alpha-adducin in memory from nematodes to humans. REFERENCE 4 (bases 1 to 3970) AUTHORS Mondini,A., Sassone,F., Civello,D.A., Garavaglia,M.L., Bazzini,C., Rodighiero,S., Vezzoli,V., Conti,F., Torielli,L., Capasso,G., Paulmichl,M. and Meyer,G. TITLE Hypertension-linked mutation of alpha-adducin increases CFTR surface expression and activity in HEK and cultured rat distal convoluted tubule cells JOURNAL PLoS ONE 7 (12), E52014 (2012) PUBMED 23284854 REMARK GeneRIF: Hypertension-linked mutation of alpha-adducin increases CFTR surface expression and activity in HEK and cultured rat distal convoluted tubule cells. REFERENCE 5 (bases 1 to 3970) AUTHORS Li,Y.Y. TITLE alpha-Adducin Gly460Trp gene mutation and essential hypertension in a Chinese population: a meta-analysis including 10,960 subjects JOURNAL PLoS ONE 7 (1), E30214 (2012) PUBMED 22272309 REMARK GeneRIF: Data show that alpha-adducin G460W gene polymorphism was linked to essential hypertension (EH) susceptibility. REFERENCE 6 (bases 1 to 3970) AUTHORS Goldberg,Y.P., Lin,B.Y., Andrew,S.E., Nasir,J., Graham,R., Glaves,M.L., Hutchinson,G., Theilmann,J., Ginzinger,D.G., Schappert,K. et al. TITLE Cloning and mapping of the alpha-adducin gene close to D4S95 and assessment of its relationship to Huntington disease JOURNAL Hum. Mol. Genet. 1 (9), 669-675 (1992) PUBMED 1284592 REFERENCE 7 (bases 1 to 3970) AUTHORS Taylor,S.A., Snell,R.G., Buckler,A., Ambrose,C., Duyao,M., Church,D., Lin,C.S., Altherr,M., Bates,G.P., Groot,N. et al. TITLE Cloning of the alpha-adducin gene from the Huntington's disease candidate region of chromosome 4 by exon amplification JOURNAL Nat. Genet. 2 (3), 223-227 (1992) PUBMED 1345173 REFERENCE 8 (bases 1 to 3970) AUTHORS Joshi,R., Gilligan,D.M., Otto,E., McLaughlin,T. and Bennett,V. TITLE Primary structure and domain organization of human alpha and beta adducin JOURNAL J. Cell Biol. 115 (3), 665-675 (1991) PUBMED 1840603 REFERENCE 9 (bases 1 to 3970) AUTHORS Mangeat,P.H. TITLE Interaction of biological membranes with the cytoskeletal framework of living cells JOURNAL Biol. Cell 64 (3), 261-281 (1988) PUBMED 2976282 REMARK Review article REFERENCE 10 (bases 1 to 3970) AUTHORS Gardner,K. and Bennett,V. TITLE Modulation of spectrin-actin assembly by erythrocyte adducin JOURNAL Nature 328 (6128), 359-362 (1987) PUBMED 3600811 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI460192.1, CR995783.1, X58141.1, CX783962.1 and BU729599.1. On Sep 14, 2011 this sequence version replaced gi:29826318. Summary: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) utilizes an in-frame alternate splice site in the coding region, compared to variant 2. This results in a shorter protein (isoform a), compared to isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns ERS025081, ERS025082 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-151 BI460192.1 25-175 152-771 CR995783.1 127-746 772-1944 X58141.1 738-1910 1945-2184 CX783962.1 551-790 2185-3941 X58141.1 2151-3907 3942-3970 BU729599.1 1-29 c FEATURES Location/Qualifiers source 1..3970 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="4" /map="4p16.3" gene 1..3970 /gene="ADD1" /gene_synonym="ADDA" /note="adducin 1 (alpha)" /db_xref="GeneID:118" /db_xref="HGNC:243" /db_xref="HPRD:00036" /db_xref="MIM:102680" exon 1..168 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 95 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:4960" exon 169..383 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 170 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:4970" variation 172 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:370218258" misc_feature 174..176 /gene="ADD1" /gene_synonym="ADDA" /note="upstream in-frame stop codon" variation 188 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:201464918" CDS 189..2402 /gene="ADD1" /gene_synonym="ADDA" /note="isoform a is encoded by transcript variant 1; erythrocyte adducin alpha subunit; alpha-adducin" /codon_start=1 /product="alpha-adducin isoform a" /protein_id="NP_001110.2" /db_xref="GI:29826319" /db_xref="CCDS:CCDS43205.1" /db_xref="GeneID:118" /db_xref="HGNC:243" /db_xref="HPRD:00036" /db_xref="MIM:102680" /translation="
MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS
" misc_feature 222..224 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 273..275 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="proteolytic cleavage site; modified site" /db_xref="HPRD:02799" misc_feature 363..365 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine, by PKA; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 612..1244 /gene="ADD1" /gene_synonym="ADDA" /note="Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398" /db_xref="CDD:29521" misc_feature order(639..641,651..653,675..677,750..752,756..761, 909..911,915..920,933..941,963..965,969..974,1005..1007, 1089..1091,1122..1124,1143..1145,1155..1157,1176..1178, 1230..1232) /gene="ADD1" /gene_synonym="ADDA" /note="intersubunit interface [polypeptide binding]; other site" /db_xref="CDD:29521" misc_feature order(690..692,741..746,819..827,903..905,909..911, 1092..1094) /gene="ADD1" /gene_synonym="ADDA" /note="active site" /db_xref="CDD:29521" misc_feature 810..812 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="proteolytic cleavage site; modified site" /db_xref="HPRD:02799" misc_feature order(903..905,909..911,1092..1094) /gene="ADD1" /gene_synonym="ADDA" /note="Zn2+ binding site [ion binding]; other site" /db_xref="CDD:29521" misc_feature 1179..1181 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphothreonine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1188..1190 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1260..1262 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1260..1262 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 1260..1262 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 1410..1412 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine, by PKA; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1410..1412 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" /db_xref="HPRD:03382" misc_feature 1446..1448 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 1455..1457 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 1473..1475 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 1479..1481 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1494..1496 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine, by PKA; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1494..1496 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" /db_xref="HPRD:03382" misc_feature 1521..1523 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphothreonine, by ROCK2; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1521..1523 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" /db_xref="HPRD:03414" misc_feature 1578..1580 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 1581..1583 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1581..1583 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 1626..1628 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphothreonine, by ROCK2; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1626..1628 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" /db_xref="HPRD:03414" misc_feature 1629..1631 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine, by PKA; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 1944..1946 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 2025..2027 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2028..2030 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2085..2087 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="proteolytic cleavage site; modified site" /db_xref="HPRD:02799" misc_feature 2193..2195 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2211..2213 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2271..2273 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" /db_xref="HPRD:01501" misc_feature 2307..2309 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 2307..2309 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2316..2318 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 2316..2318 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2328..2330 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 2334..2336 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine, by PKC; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" misc_feature 2334..2336 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2337..2390 /gene="ADD1" /gene_synonym="ADDA" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P35611.2); Region: Interaction with calmodulin (Potential)" misc_feature 2364..2366 /gene="ADD1" /gene_synonym="ADDA" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine, by PKA and PKC; propagated from UniProtKB/Swiss-Prot (P35611.2); phosphorylation site" variation 196 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:113693299" variation 204 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:2295497" variation 209 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:373384333" variation 211 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:188077552" variation 213 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:191878690" variation 232 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:33915400" variation 233 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:140936293" variation 248 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:144130874" variation 263 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:199855248" variation 264 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:370911124" variation 273 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:374139420" variation 293 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:371001898" variation 317 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:146519461" variation 341 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:140325938" variation 342 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:374585294" variation 372 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:369221957" exon 384..546 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 406 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:200647918" variation 414 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:371281109" variation 438 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:113259674" variation 477 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:374828271" variation 481 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:113362280" variation 497 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:376198993" exon 547..698 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 557 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:113845034" variation 573 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:201569938" variation 599 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:137927328" variation 610 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:369225621" variation 631 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:142505906" variation 665 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:192899881" variation 672 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:374216380" variation 686 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:145970845" exon 699..779 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 705 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:200011993" exon 780..929 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 790 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:373396685" variation 867 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:376684645" variation 879 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:148183016" variation 883 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:370683439" variation 890 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:112813723" variation 896 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:16843169" variation 897 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:140019569" variation 899 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:370483088" variation 900 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:374392385" variation 914 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:374132765" variation 915 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:201637172" variation 919 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:201212816" exon 930..1073 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 945 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:367745191" variation 968 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:371614186" variation 972 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:199940053" variation 996 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:4971" variation 1011 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:200904553" variation 1017 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:374634966" variation 1025 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:144809220" variation 1034 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:368155471" variation 1044 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:374411956" variation 1060 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:372354688" exon 1074..1172 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 1087 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:202124018" variation 1101 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:147521356" variation 1135 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:372777117" variation 1171 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:374826670" exon 1173..1349 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 1248 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:145933934" variation 1257 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:139972650" variation 1275 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:201570559" variation 1286 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:372679891" variation 1300 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:145398161" variation 1316 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:4972" variation 1325 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:200470659" variation 1340 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:145251004" variation 1347 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:4690006" exon 1350..1601 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 1350 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:376166483" variation 1375 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:142283650" variation 1382 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:138254700" variation 1421 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:373803874" variation 1469 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:367978307" variation 1484 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:36115602" variation 1495 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:140440262" variation 1519 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:34225447" variation 1524 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:190509107" variation 1550 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:142830875" variation 1560 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:200429788" variation 1566 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:4961" variation 1589 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:112663622" exon 1602..1703 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 1652..1653 /gene="ADD1" /gene_synonym="ADDA" /replace="" /replace="g" /db_xref="dbSNP:35959080" exon 1704..1793 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 1717 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:4962" variation 1727 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:201174055" variation 1728 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:199531446" variation 1770 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:146536048" variation 1785 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:372341933" exon 1794..1950 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 1864 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:370522818" variation 1865 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:150105286" variation 1897 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:13306092" variation 1914 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:200523186" variation 1931 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:199783611" variation 1945 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:4963" exon 1951..2049 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 1961 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:149239903" variation 1962 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:374663989" variation 1969 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:143465381" variation 1971 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:140746314" variation 1976 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:143366247" variation 1998 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:201305164" variation 2000 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:147536529" variation 2011 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:140040570" variation 2017 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:199501257" variation 2033 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:34021320" STS 2047..2188 /gene="ADD1" /gene_synonym="ADDA" /standard_name="SHGC-59864" /db_xref="UniSTS:55191" exon 2050..3955 /gene="ADD1" /gene_synonym="ADDA" /inference="alignment:Splign:1.39.8" variation 2059 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:13306093" variation 2066 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:371407792" variation 2092 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:139804863" variation 2114 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:201859948" variation 2139 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:368753524" variation 2166 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:369305915" variation 2169 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:200594905" variation 2171 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:11792" variation 2188 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:371284874" variation 2222 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:182709254" variation 2225 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:373749278" variation 2279 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:200759802" variation 2292 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:377188092" variation 2294 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:34737322" variation 2306 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:370689290" variation 2309 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:149767458" variation 2310 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:200088947" variation 2348 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:374830082" variation 2349 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:145730078" variation 2350 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:139520568" variation 2360 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:202176832" variation 2385 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:367859125" variation 2389 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:376347147" variation 2409 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:373714403" variation 2434 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:111470742" variation 2514 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:187534255" variation 2617 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:75083667" variation 2648 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:146995313" variation 2675 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:373517486" variation 2681 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:369529656" variation 2690 /gene="ADD1" /gene_synonym="ADDA" /replace="g" /replace="t" /db_xref="dbSNP:35590072" variation 2712 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:4965" STS 2729..2826 /gene="ADD1" /gene_synonym="ADDA" /standard_name="D4S2503E" /db_xref="UniSTS:150963" variation 2749 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:374574919" variation 2800 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:370548276" variation 2815 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:377009122" variation 2836 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:11555367" STS 2874..3108 /gene="ADD1" /gene_synonym="ADDA" /standard_name="GDB:197234" /db_xref="UniSTS:155930" variation 2893 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:78036872" variation 2963 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:371401014" variation 2987 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:184680480" variation 3016 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:4966" variation 3028 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:138194142" variation 3063 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:34834793" variation 3092 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:4967" variation 3124 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:116367921" variation 3166 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:373920776" variation 3332 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:36038921" variation 3342 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:4968" variation 3344 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="t" /db_xref="dbSNP:34819539" variation 3349 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:4741" variation 3351 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:35742396" variation 3355 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:143763593" variation 3395 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:35640772" variation 3499 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:4969" variation 3509 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:34189603" variation 3529 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:147451123" variation 3555 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="g" /db_xref="dbSNP:13306094" variation 3579 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:35617702" variation 3584 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:35170535" variation 3630 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:184829156" variation 3644 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:189723463" variation 3645 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:181195398" variation 3647 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:148092322" variation 3665 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:11555368" variation 3668 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:13306095" STS 3697..3790 /gene="ADD1" /gene_synonym="ADDA" /standard_name="IB433" /db_xref="UniSTS:71609" variation 3700..3701 /gene="ADD1" /gene_synonym="ADDA" /replace="" /replace="ct" /db_xref="dbSNP:375620638" variation 3704 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:188245985" variation 3714 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="g" /db_xref="dbSNP:13306096" variation 3758 /gene="ADD1" /gene_synonym="ADDA" /replace="c" /replace="t" /db_xref="dbSNP:112860382" variation 3920 /gene="ADD1" /gene_synonym="ADDA" /replace="a" /replace="c" /db_xref="dbSNP:3201445" polyA_signal 3923..3928 /gene="ADD1" /gene_synonym="ADDA" polyA_site 3955 /gene="ADD1" /gene_synonym="ADDA" ORIGIN
gcacccaggtcgggcggtgggggcgagcggaggggctgaggggcggagaggcctggcgggccgctgctgcgggccaggggacgggggcggagccggagccggagccgacgggcggtggccgcactgggaccccggaatcccgcgcgctgcccacgattcgcttctgaggaacctagaaagattgtacaatgaatggtgattctcgtgctgcggtggtgacctcaccacccccgaccacagcccctcacaaggagaggtacttcgaccgagtagatgagaacaacccagagtacttgagggagaggaacatggcaccagaccttcgccaggacttcaacatgatggagcaaaagaagagggtgtccatgattctgcaaagccctgctttctgtgaagaattggaatcaatgatacaggagcaatttaagaaggggaagaaccccacaggcctattggcattacagcagattgcagattttatgaccacgaatgtaccaaatgtctacccagcagctccgcaaggagggatggctgccttaaacatgagtcttggtatggtgactcctgtgaacgatcttagaggatctgattctattgcgtatgacaaaggagagaagttattacggtgtaaattggcagcgttttatagactagcagatctctttgggtggtctcagcttatctacaatcatatcacaaccagagtgaactccgagcaggaacacttcctcattgtcccttttgggcttctttacagtgaagtgactgcatccagtttggttaagatcaatctacaaggagatatagtagatcgtggaagcactaatctgggagtgaatcaggccggcttcaccttacactctgcaatttatgctgcacgcccggacgtgaagtgcgtcgtgcacattcacaccccagcaggggctgcggtctctgcaatgaaatgtggcctcttgccaatctccccggaggcgctttcccttggagaagtggcttatcatgactaccatggcattctggttgatgaagaggaaaaagttttgattcagaaaaatctggggcctaaaagcaaggttcttattctccggaaccatgggctcgtgtcagttggagagagcgttgaggaggccttctattacatccataaccttgtggttgcctgtgagatccaggttcgaactctggccagtgcaggaggaccagacaacttagtcctgctgaatcctgagaagtacaaagccaagtcccgttccccagggtctccggtaggggaaggcactggatcgcctcccaagtggcagattggtgagcaggaatttgaagccctcatgcggatgctcgataatctgggctacagaactggctacccttatcgataccctgctctgagagagaagtctaaaaaatacagcgatgtggaggttcctgctagtgtcacaggttactcctttgctagtgacggtgattcgggcacttgctccccactcagacacagttttcagaagcagcagcgggagaagacaagatggctgaactctggccggggcgacgaagcttccgaggaagggcagaatggaagcagtcccaagtcgaagactaagtggactaaagaggatggacatagaacttccacctctgctgtccctaacctgtttgttccattgaacactaacccaaaagaggtccaggagatgaggaacaagatccgagagcagaatttacaggacattaagacggctggccctcagtcccaggttttgtgtggtgtagtgatggacaggagcctcgtccagggagagctggtgacggcctccaaggccatcattgaaaaggagtaccagccccacgtcattgtgagcaccacgggccccaaccccttcaccacactcacagaccgtgagctggaggagtaccgcagggaggtggagaggaagcagaagggctctgaagagaatctggacgaggctagagaacagaaagaaaagagtcctccagaccagcctgcggtcccccacccgcctcccagcactcccatcaagctggaggaagaccttgtgccggagccgactactggagatgacagtgatgctgccacctttaagccaactctccccgatctgtcccctgatgaaccttcagaagcactcggcttcccaatgttagagaaggaggaggaagcccatagacccccaagccccactgaggcccctactgaggccagccccgagccagccccagacccagccccggtggctgaagaggctgccccctcagctgtcgaggagggggccgccgcggaccctggcagcgatgggtctccaggcaagtccccgtccaaaaagaagaagaagttccgtaccccgtcctttctgaagaagagcaagaagaagagtgactcctgaaagccctgcgctaacactgtcctgtccggagcgaccctggctctgccagcgtccccggccacgtctgtgctctgtccttgtgtaatggaatgcaaaaaagccaagccctccgcctagaggtcccctcacgtgaccagccccgtgtagccccgggctgacccagtgtgtgctcagcagccccaccccaccctgccccttgtcctctcagagcctcagcttctgggggagacatgctctccccacaggggggaggcactaagtcatggtcctggctggaaggtactgaaggcttctgcagctttggctgcacgtcaccctcctgagcctcacctttcctgccgtccctcctgttgtgaaatcaccacattctgtctctgcttggcttcccctccaccctaaagtctcaggtgacggactcagactcctggcttcatgtggcattctctctgctcagtgatctcacttaaatctatatacaaagccttggtcccgtgaaaacactcgtgtgcccaccagcggccttgaagaggcaggtctgggccagatgctgggcaggaaaccccagcggcagatgggcctgtgtgcacccaacgtgatgctatgcatgtctgaccgacgatccctcgaccagaatcagattcaggagctcagtttctttttcacttgggtctctggattcctgtcatagggaaggtatatcaggaggggaagaggcctttctagaattttctttgagcaggtttacaatttagcttacatttttcgactgtgaacgtgaataggctgctttttgctttcttctttccagaccccacagtagagcacttttcacttatttgggggaggcttcaggggactgttctcaccttaactcagccagaaagatgccctagttgtgatcaaaggtaactcgaggtggagggtagccctggggcccctcgacatcaccgtcattgatggagcctgaaccgtgtgctcctcggcagatgctgttgttgttacttccctccaagaggctggaaaagggctcagagctgctgagcaggaaccggagggtgacccatttcaggaggtgccggtaccagcctgactaggtacaggcaagcttgtgtgggcccaacaggcccttggtagagctggtgccagatgtgggctcagatcctgggcatgatgggccgagccacctcggatcccactgattggccagccgagcgagaaccaggctgctgcatggcactgaccgccgcttccagcttcctctgagccgcagggcctgctacgcgggcaagcgtgctgcctctcttctgtgtcgttttgttgccaaggcagaatgaaaagtccttaaccgtggactcttcctttatcccctcctttaccccacatatgcaatgacttttaattttcacttttgtagtttaatcctttgtattacaacatgaaatatagttgcatatatggacaccgacttgggaggacaggtcctgaatgtcctttctccagtgtaacatgttttactcacaaataaaattctttcagcaagttccttgtctaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:118 -> Molecular function: GO:0003779 [actin binding] evidence: TAS GeneID:118 -> Molecular function: GO:0005198 [structural molecule activity] evidence: IEA GeneID:118 -> Molecular function: GO:0005516 [calmodulin binding] evidence: IEA GeneID:118 -> Molecular function: GO:0008134 [transcription factor binding] evidence: IPI GeneID:118 -> Molecular function: GO:0030507 [spectrin binding] evidence: IDA GeneID:118 -> Molecular function: GO:0042608 [T cell receptor binding] evidence: IEA GeneID:118 -> Molecular function: GO:0042803 [protein homodimerization activity] evidence: IPI GeneID:118 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IPI GeneID:118 -> Molecular function: GO:0051015 [actin filament binding] evidence: IDA GeneID:118 -> Biological process: GO:0000902 [cell morphogenesis] evidence: IEA GeneID:118 -> Biological process: GO:0001701 [in utero embryonic development] evidence: IEA GeneID:118 -> Biological process: GO:0006884 [cell volume homeostasis] evidence: IEA GeneID:118 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS GeneID:118 -> Biological process: GO:0006921 [cellular component disassembly involved in execution phase of apoptosis] evidence: TAS GeneID:118 -> Biological process: GO:0006987 [activation of signaling protein activity involved in unfolded protein response] evidence: TAS GeneID:118 -> Biological process: GO:0020027 [hemoglobin metabolic process] evidence: IEA GeneID:118 -> Biological process: GO:0030036 [actin cytoskeleton organization] evidence: IC GeneID:118 -> Biological process: GO:0030218 [erythrocyte differentiation] evidence: IEA GeneID:118 -> Biological process: GO:0030968 [endoplasmic reticulum unfolded protein response] evidence: TAS GeneID:118 -> Biological process: GO:0032092 [positive regulation of protein binding] evidence: IDA GeneID:118 -> Biological process: GO:0035264 [multicellular organism growth] evidence: IEA GeneID:118 -> Biological process: GO:0044267 [cellular protein metabolic process] evidence: TAS GeneID:118 -> Biological process: GO:0045766 [positive regulation of angiogenesis] evidence: IEA GeneID:118 -> Biological process: GO:0045807 [positive regulation of endocytosis] evidence: IEA GeneID:118 -> Biological process: GO:0048873 [homeostasis of number of cells within a tissue] evidence: IEA GeneID:118 -> Biological process: GO:0051016 [barbed-end actin filament capping] evidence: IDA GeneID:118 -> Biological process: GO:0051017 [actin filament bundle assembly] evidence: IDA GeneID:118 -> Biological process: GO:0071300 [cellular response to retinoic acid] evidence: IEA GeneID:118 -> Cellular component: GO:0005634 [nucleus] evidence: IDA GeneID:118 -> Cellular component: GO:0005829 [cytosol] evidence: TAS GeneID:118 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA GeneID:118 -> Cellular component: GO:0008290 [F-actin capping protein complex] evidence: IDA GeneID:118 -> Cellular component: GO:0014069 [postsynaptic density] evidence: IEA GeneID:118 -> Cellular component: GO:0043197 [dendritic spine] evidence: IEA GeneID:118 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
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