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2019-03-25 15:08:53, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001101               1852 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens actin, beta (ACTB), mRNA.
ACCESSION   NM_001101
VERSION     NM_001101.3  GI:168480144
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1852)
  AUTHORS   Lui,Y.L., Lin,Z., Lee,J.J., Chow,V.T., Poh,C.L. and Tan,E.L.
  TITLE     Beta-actin variant is necessary for Enterovirus 71 replication
  JOURNAL   Biochem. Biophys. Res. Commun. 433 (4), 607-610 (2013)
   PUBMED   23535377
  REMARK    GeneRIF: Two variants of beta-actin, beta1 and beta2 were found in
            the Enterovirus 71-susceptible rhabdomyosarcoma cells, compared to
            Enterovirus 71-resistant cells that contains only one variant
            beta1.
REFERENCE   2  (bases 1 to 1852)
  AUTHORS   Thompson,P.M., Tolbert,C.E. and Campbell,S.L.
  TITLE     Vinculin and metavinculin: oligomerization and interactions with
            F-actin
  JOURNAL   FEBS Lett. 587 (8), 1220-1229 (2013)
   PUBMED   23466368
  REMARK    GeneRIF: Studies indicate that that vinculin not only bundles actin
            filaments but can also cap these filaments and promote actin
            polymerization.
            Review article
REFERENCE   3  (bases 1 to 1852)
  AUTHORS   Elam,W.A., Kang,H. and De la Cruz,E.M.
  TITLE     Biophysics of actin filament severing by cofilin
  JOURNAL   FEBS Lett. 587 (8), 1215-1219 (2013)
   PUBMED   23395798
  REMARK    GeneRIF: Studies indicate that cofilin binds actin
            stoichiometrically - one cofilin molecule per actin filament
            subunit.
            Review article
REFERENCE   4  (bases 1 to 1852)
  AUTHORS   Wakimoto,H., Shimodo,M., Satoh,Y., Kitagawa,Y., Takeuchi,K.,
            Gotoh,B. and Itoh,M.
  TITLE     F-actin modulates measles virus cell-cell fusion and assembly by
            altering the interaction between the matrix protein and the
            cytoplasmic tail of hemagglutinin
  JOURNAL   J. Virol. 87 (4), 1974-1984 (2013)
   PUBMED   23221571
  REMARK    GeneRIF: These results indicate that F-actin in association with
            the M protein alters the interaction between the M and H proteins,
            thereby modulating measles virus cell-cell fusion and assembly.
REFERENCE   5  (bases 1 to 1852)
  AUTHORS   Zhang,L., Xiao,R., Xiong,J., Leng,J., Ehtisham,A., Hu,Y., Ding,Q.,
            Xu,H., Liu,S., Wang,J., Tang,D.G. and Zhang,Q.
  TITLE     Activated ERM protein plays a critical role in drug resistance of
            MOLT4 cells induced by CCL25
  JOURNAL   PLoS ONE 8 (1), E52384 (2013)
   PUBMED   23326330
  REMARK    GeneRIF: Data suggest that P-glycoprotein associate with the
            F-actin cytoskeleton through ezrin/radixin/moesin (ERM) in
            CCR9/CCL25 induced multidrug resistance of acute T-lymphocytic
            leukemia (T-ALL) cells.
REFERENCE   6  (bases 1 to 1852)
  AUTHORS   Horisberger,M.A.
  TITLE     Interferon-induced human protein MxA is a GTPase which binds
            transiently to cellular proteins
  JOURNAL   J. Virol. 66 (8), 4705-4709 (1992)
   PUBMED   1629950
REFERENCE   7  (bases 1 to 1852)
  AUTHORS   Harris,D.E., Warshaw,D.M. and Periasamy,M.
  TITLE     Nucleotide sequences of the rabbit alpha-smooth-muscle and
            beta-non-muscle actin mRNAs
  JOURNAL   Gene 112 (2), 265-266 (1992)
   PUBMED   1555776
REFERENCE   8  (bases 1 to 1852)
  AUTHORS   Habets,G.G., van der Kammen,R.A., Willemsen,V., Balemans,M.,
            Wiegant,J. and Collard,J.G.
  TITLE     Sublocalization of an invasion-inducing locus and other genes on
            human chromosome 7
  JOURNAL   Cytogenet. Cell Genet. 60 (3-4), 200-205 (1992)
   PUBMED   1505215
REFERENCE   9  (bases 1 to 1852)
  AUTHORS   Smith,S.S., Kelly,K.H. and Jockusch,B.M.
  TITLE     Actin co-purifies with RNA polymerase II
  JOURNAL   Biochem. Biophys. Res. Commun. 86 (1), 161-166 (1979)
   PUBMED   435297
REFERENCE   10 (bases 1 to 1852)
  AUTHORS   Vandekerckhove,J. and Weber,K.
  TITLE     Mammalian cytoplasmic actins are the products of at least two genes
            and differ in primary structure in at least 25 identified positions
            from skeletal muscle actins
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 75 (3), 1106-1110 (1978)
   PUBMED   274701
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK130157.1 and BC009636.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Feb 22, 2008 this sequence version replaced gi:5016088.
            
            Summary: This gene encodes one of six different actin proteins.
            Actins are highly conserved proteins that are involved in cell
            motility, structure, and integrity. This actin is a major
            constituent of the contractile apparatus and one of the two
            nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK222925.1, BC014861.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1336              AK130157.1         1-1336
            1337-1852           BC009636.1         71-586
FEATURES             Location/Qualifiers
     source          1..1852
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p22"
     gene            1..1852
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /note="actin, beta"
                     /db_xref="GeneID:60"
                     /db_xref="HGNC:132"
                     /db_xref="HPRD:00032"
                     /db_xref="MIM:102630"
     exon            1..78
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /inference="alignment:Splign:1.39.8"
     variation       12
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13447389"
     variation       71
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:11546897"
     exon            79..207
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /inference="alignment:Splign:1.39.8"
     variation       81
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546942"
     variation       84
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11546943"
     CDS             85..1212
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /note="beta cytoskeletal actin; PS1TP5-binding protein 1"
                     /codon_start=1
                     /product="actin, cytoplasmic 1"
                     /protein_id="NP_001092.1"
                     /db_xref="GI:4501885"
                     /db_xref="CCDS:CCDS5341.1"
                     /db_xref="GeneID:60"
                     /db_xref="HGNC:132"
                     /db_xref="HPRD:00032"
                     /db_xref="MIM:102630"
                     /translation="
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
"
     misc_feature    88..90
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-acetylaspartate, in Actin, cytoplasmic 1,
                     N-terminally processed; propagated from
                     UniProtKB/Swiss-Prot (P60709.1); acetylation site"
     misc_feature    91..1209
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /note="Actin; Region: Actin; pfam00022"
                     /db_xref="CDD:200935"
     misc_feature    106..627
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cd00012"
                     /db_xref="CDD:212657"
     misc_feature    order(115..126,130..132,136..138,493..495,544..555)
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212657"
     misc_feature    301..303
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="methylation site"
     misc_feature    613..615
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="ADP-ribosylation site; glycosylation site"
     misc_feature    736..738
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    order(937..939,1204..1206)
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="disulfide bridge bond"
     misc_feature    964..966
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    964..966
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     variation       104
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546916"
     variation       106
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546895"
     STS             109..361
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC317352P1"
                     /db_xref="UniSTS:273088"
     STS             117..269
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC97568P1"
                     /db_xref="UniSTS:273653"
     variation       161
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546929"
     variation       191
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:11546921"
     variation       193
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546914"
     STS             202..276
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC24942P1"
                     /db_xref="UniSTS:272277"
     exon            208..447
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /inference="alignment:Splign:1.39.8"
     STS             223..722
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC85795P4"
                     /db_xref="UniSTS:273493"
     STS             226..327
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC86716P1"
                     /db_xref="UniSTS:273551"
     STS             247..1155
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC108612P1"
                     /db_xref="UniSTS:270141"
     STS             250..1155
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC110143P1"
                     /db_xref="UniSTS:270184"
     STS             250..627
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC201106P1"
                     /db_xref="UniSTS:271883"
     STS             250..485
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC137792P1"
                     /db_xref="UniSTS:270855"
     variation       252
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13447398"
     STS             272..808
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC133998P8"
                     /db_xref="UniSTS:270713"
     variation       286
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546904"
     variation       290
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546912"
     variation       292
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546913"
     STS             308..550
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="ACTB-L"
                     /db_xref="UniSTS:261993"
     STS             310..769
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC137757P2"
                     /db_xref="UniSTS:270854"
     STS             313..666
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC23952P1"
                     /db_xref="UniSTS:272216"
     STS             322..685
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC129447P1"
                     /db_xref="UniSTS:270591"
     STS             339..468
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="LOC345651"
                     /db_xref="UniSTS:265879"
     STS             340..669
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC356969P12"
                     /db_xref="UniSTS:273274"
     STS             352..885
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC22644P1"
                     /db_xref="UniSTS:272120"
     variation       371
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546931"
     variation       375
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546933"
     variation       376
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546910"
     variation       379
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:11546932"
     STS             440..625
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="RI01350"
                     /db_xref="UniSTS:463064"
     exon            448..886
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /inference="alignment:Splign:1.39.8"
     STS             451..945
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC224995P1"
                     /db_xref="UniSTS:272113"
     STS             453..770
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC99880P2"
                     /db_xref="UniSTS:273691"
     STS             453..719
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC152551P1"
                     /db_xref="UniSTS:271229"
     STS             455..811
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC85361P1"
                     /db_xref="UniSTS:273471"
     STS             457..818
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC180915P1"
                     /db_xref="UniSTS:271667"
     STS             466..719
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC275467P1"
                     /db_xref="UniSTS:272382"
     variation       504
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13447405"
     variation       510
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:79074016"
     STS             566..1030
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC117780P1"
                     /db_xref="UniSTS:270340"
     variation       566
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546901"
     variation       585
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1064678"
     STS             602..1207
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC109669P1"
                     /db_xref="UniSTS:270176"
     variation       603..604
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546944"
     STS             608..766
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC133768P1"
                     /db_xref="UniSTS:270660"
     variation       632
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546934"
     STS             652..1094
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC26753P1"
                     /db_xref="UniSTS:272350"
     STS             673..1168
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC138261P1"
                     /db_xref="UniSTS:270864"
     variation       698..699
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546945"
     variation       737
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11546898"
     variation       743
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546894"
     STS             759..1204
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="GDB:624560"
                     /db_xref="UniSTS:158349"
     STS             790..1028
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC101699P1"
                     /db_xref="UniSTS:270062"
     STS             793..931
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="REN115794"
                     /db_xref="UniSTS:440589"
     variation       812
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546899"
     variation       841
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546925"
     variation       854
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546930"
     STS             867..1095
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC302066P1"
                     /db_xref="UniSTS:272483"
     STS             878..1079
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC109689P1"
                     /db_xref="UniSTS:270178"
     STS             878..1079
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC110200P1"
                     /db_xref="UniSTS:270185"
     exon            887..1068
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /inference="alignment:Splign:1.39.8"
     STS             890..1172
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC305683P4"
                     /db_xref="UniSTS:272560"
     variation       915
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546896"
     STS             934..1155
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC20960P1"
                     /db_xref="UniSTS:272003"
     STS             955..1079
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC109445P1"
                     /db_xref="UniSTS:270169"
     STS             965..1169
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC24561P1"
                     /db_xref="UniSTS:272264"
     variation       984
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13447406"
     variation       987
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13447407"
     STS             1007..1165
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC305873P2"
                     /db_xref="UniSTS:272568"
     variation       1026
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546939"
     variation       1035
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13447408"
     STS             1064..1381
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC151817P1"
                     /db_xref="UniSTS:271183"
     exon            1069..1812
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1098
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1064790"
     variation       1109
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546902"
     variation       1128
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13447409"
     STS             1136..1375
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="aa658676"
                     /db_xref="UniSTS:186920"
     STS             1145..1266
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC151001P2"
                     /db_xref="UniSTS:271130"
     variation       1180
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546903"
     STS             1249..1490
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="G15871"
                     /db_xref="UniSTS:6889"
     variation       1299
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1065094"
     variation       1312
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13447410"
     variation       1314
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:17136418"
     variation       1321
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546928"
     STS             1356..1587
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="ECD18704"
                     /db_xref="UniSTS:299714"
     STS             1357..1784
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="PMC21334P2"
                     /db_xref="UniSTS:272037"
     STS             1358..1516
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /standard_name="G49387"
                     /db_xref="UniSTS:109142"
     variation       1413
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546911"
     variation       1422
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13447411"
     variation       1435
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546941"
     variation       1444
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546919"
     variation       1447
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546918"
     variation       1472
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546906"
     variation       1475
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11546935"
     variation       1483
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546927"
     variation       1492
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546905"
     variation       1527
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1065729"
     variation       1581
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546923"
     variation       1594
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3210647"
     variation       1645
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3206243"
     variation       1665
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3210032"
     variation       1686
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3210108"
     variation       1717
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13447412"
     variation       1723
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11546924"
     polyA_signal    1787..1792
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
     polyA_site      1812
                     /gene="ACTB"
                     /gene_synonym="BRWS1; PS1TP5BP1"
ORIGIN      
accgccgagaccgcgtccgccccgcgagcacagagcctcgcctttgccgatccgccgcccgtccacacccgccgccagctcaccatggatgatgatatcgccgcgctcgtcgtcgacaacggctccggcatgtgcaaggccggcttcgcgggcgacgatgccccccgggccgtcttcccctccatcgtggggcgccccaggcaccagggcgtgatggtgggcatgggtcagaaggattcctatgtgggcgacgaggcccagagcaagagaggcatcctcaccctgaagtaccccatcgagcacggcatcgtcaccaactgggacgacatggagaaaatctggcaccacaccttctacaatgagctgcgtgtggctcccgaggagcaccccgtgctgctgaccgaggcccccctgaaccccaaggccaaccgcgagaagatgacccagatcatgtttgagaccttcaacaccccagccatgtacgttgctatccaggctgtgctatccctgtacgcctctggccgtaccactggcatcgtgatggactccggtgacggggtcacccacactgtgcccatctacgaggggtatgccctcccccatgccatcctgcgtctggacctggctggccgggacctgactgactacctcatgaagatcctcaccgagcgcggctacagcttcaccaccacggccgagcgggaaatcgtgcgtgacattaaggagaagctgtgctacgtcgccctggacttcgagcaagagatggccacggctgcttccagctcctccctggagaagagctacgagctgcctgacggccaggtcatcaccattggcaatgagcggttccgctgccctgaggcactcttccagccttccttcctgggcatggagtcctgtggcatccacgaaactaccttcaactccatcatgaagtgtgacgtggacatccgcaaagacctgtacgccaacacagtgctgtctggcggcaccaccatgtaccctggcattgccgacaggatgcagaaggagatcactgccctggcacccagcacaatgaagatcaagatcattgctcctcctgagcgcaagtactccgtgtggatcggcggctccatcctggcctcgctgtccaccttccagcagatgtggatcagcaagcaggagtatgacgagtccggcccctccatcgtccaccgcaaatgcttctaggcggactatgacttagttgcgttacaccctttcttgacaaaacctaacttgcgcagaaaacaagatgagattggcatggctttatttgttttttttgttttgttttggttttttttttttttttggcttgactcaggatttaaaaactggaacggtgaaggtgacagcagtcggttggagcgagcatcccccaaagttcacaatgtggccgaggactttgattgcacattgttgtttttttaatagtcattccaaatatgagatgcgttgttacaggaagtcccttgccatcctaaaagccaccccacttctctctaaggagaatggcccagtcctctcccaagtccacacaggggaggtgatagcattgctttcgtgtaaattatgtaatgcaaaatttttttaatcttcgccttaatacttttttattttgttttattttgaatgatgagccttcgtgcccccccttcccccttttttgtcccccaacttgagatgtatgaaggcttttggtctccctgggagtgggtggaggcagccagggcttacctgtacactgacttgagaccagttgaataaaagtgcacaccttaaaaatgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:60 -> Molecular function: GO:0005200 [structural constituent of cytoskeleton] evidence: TAS
            GeneID:60 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:60 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
            GeneID:60 -> Molecular function: GO:0019894 [kinesin binding] evidence: IPI
            GeneID:60 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
            GeneID:60 -> Molecular function: GO:0030957 [Tat protein binding] evidence: IPI
            GeneID:60 -> Molecular function: GO:0050998 [nitric-oxide synthase binding] evidence: IPI
            GeneID:60 -> Biological process: GO:0006457 [protein folding] evidence: TAS
            GeneID:60 -> Biological process: GO:0006928 [cellular component movement] evidence: TAS
            GeneID:60 -> Biological process: GO:0007411 [axon guidance] evidence: TAS
            GeneID:60 -> Biological process: GO:0007596 [blood coagulation] evidence: TAS
            GeneID:60 -> Biological process: GO:0016044 [cellular membrane organization] evidence: TAS
            GeneID:60 -> Biological process: GO:0034329 [cell junction assembly] evidence: TAS
            GeneID:60 -> Biological process: GO:0034332 [adherens junction organization] evidence: TAS
            GeneID:60 -> Biological process: GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] evidence: TAS
            GeneID:60 -> Biological process: GO:0044267 [cellular protein metabolic process] evidence: TAS
            GeneID:60 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
            GeneID:60 -> Biological process: GO:0045216 [cell-cell junction organization] evidence: TAS
            GeneID:60 -> Biological process: GO:0051084 ['de novo' posttranslational protein folding] evidence: TAS
            GeneID:60 -> Cellular component: GO:0005737 [cytoplasm] evidence: TAS
            GeneID:60 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:60 -> Cellular component: GO:0005856 [cytoskeleton] evidence: TAS
            GeneID:60 -> Cellular component: GO:0014069 [postsynaptic density] evidence: IEA
            GeneID:60 -> Cellular component: GO:0030424 [axon] evidence: IEA
            GeneID:60 -> Cellular component: GO:0030529 [ribonucleoprotein complex] evidence: IDA
            GeneID:60 -> Cellular component: GO:0030863 [cortical cytoskeleton] evidence: IEA
            GeneID:60 -> Cellular component: GO:0035267 [NuA4 histone acetyltransferase complex] evidence: IDA
            GeneID:60 -> Cellular component: GO:0070062 [extracellular vesicular exosome] evidence: IDA
            GeneID:60 -> Cellular component: GO:0070688 [MLL5-L complex] evidence: IDA

by @meso_cacase at DBCLS
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