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2024-04-20 14:08:01, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001100400            2745 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens PDS5, regulator of cohesion maintenance, homolog A (S.
            cerevisiae) (PDS5A), transcript variant 3, mRNA.
ACCESSION   NM_001100400
VERSION     NM_001100400.1  GI:155030219
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2745)
  AUTHORS   Capalbo,G., Muller-Kuller,T., Ottmann,O.G., Hoelzer,D. and
            Scheuring,U.J.
  TITLE     HIV-1 infection suppresses expression of host cell cycle-associated
            gene PDS5A
  JOURNAL   Intervirology 55 (4), 263-275 (2012)
   PUBMED   21865657
  REMARK    GeneRIF: The data show a downregulation of proliferation-associated
            host gene PDS5A and suggest a role of PDS5A in HIV-1-induced
            cellular pathogenesis but not viral replication.
REFERENCE   2  (bases 1 to 2745)
  AUTHORS   Oshikawa,M., Tsutsui,C., Ikegami,T., Fuchida,Y., Matsubara,M.,
            Toyama,S., Usami,R., Ohtoko,K. and Kato,S.
  TITLE     Full-length transcriptome analysis of human retina-derived cell
            lines ARPE-19 and Y79 using the vector-capping method
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 52 (9), 6662-6670 (2011)
   PUBMED   21697133
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2745)
  AUTHORS   Hagemann,C., Weigelin,B., Schommer,S., Schulze,M., Al-Jomah,N.,
            Anacker,J., Gerngras,S., Kuhnel,S., Kessler,A.F., Polat,B.,
            Ernestus,R.I., Patel,R. and Vince,G.H.
  TITLE     The cohesin-interacting protein, precocious dissociation of sisters
            5A/sister chromatid cohesion protein 112, is up-regulated in human
            astrocytic tumors
  JOURNAL   Int. J. Mol. Med. 27 (1), 39-51 (2011)
   PUBMED   21069257
  REMARK    GeneRIF: Data show that the siRNA-mediated knockdown of Pds5A
            affects sister chromatid cohesion but does not influence mitotic
            checkpoint function or the proliferation and survival of
            glioblastoma multiforme cells.
REFERENCE   4  (bases 1 to 2745)
  AUTHORS   Terret,M.E., Sherwood,R., Rahman,S., Qin,J. and Jallepalli,P.V.
  TITLE     Cohesin acetylation speeds the replication fork
  JOURNAL   Nature 462 (7270), 231-234 (2009)
   PUBMED   19907496
REFERENCE   5  (bases 1 to 2745)
  AUTHORS   Zhang,H., Liu,Y., Wang,Y., Li,G., Luo,Z., Jiang,Pf., Li,F., Wang,S.
            and Deng,K.
  TITLE     [Analysis of deafness gene mutations by gene chip and its clinical
            significance]
  JOURNAL   Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 23 (22), 1032-1035
            (2009)
   PUBMED   20359100
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 2745)
  AUTHORS   Losada,A., Yokochi,T. and Hirano,T.
  TITLE     Functional contribution of Pds5 to cohesin-mediated cohesion in
            human cells and Xenopus egg extracts
  JOURNAL   J. Cell. Sci. 118 (PT 10), 2133-2141 (2005)
   PUBMED   15855230
REFERENCE   7  (bases 1 to 2745)
  AUTHORS   Rankin,S., Ayad,N.G. and Kirschner,M.W.
  TITLE     Sororin, a substrate of the anaphase-promoting complex, is required
            for sister chromatid cohesion in vertebrates
  JOURNAL   Mol. Cell 18 (2), 185-200 (2005)
   PUBMED   15837422
  REMARK    Erratum:[Mol Cell. 2005 May 27;18(5):609]
REFERENCE   8  (bases 1 to 2745)
  AUTHORS   Kumar,D., Sakabe,I., Patel,S., Zhang,Y., Ahmad,I., Gehan,E.A.,
            Whiteside,T.L. and Kasid,U.
  TITLE     SCC-112, a novel cell cycle-regulated molecule, exhibits reduced
            expression in human renal carcinomas
  JOURNAL   Gene 328, 187-196 (2004)
   PUBMED   15019998
  REMARK    GeneRIF: Findings suggest that the SCC-112 gene expression is
            likely to be associated with normal cell growth and proliferation.
REFERENCE   9  (bases 1 to 2745)
  AUTHORS   Gregson,H.C., Schmiesing,J.A., Kim,J.S., Kobayashi,T., Zhou,S. and
            Yokomori,K.
  TITLE     A potential role for human cohesin in mitotic spindle aster
            assembly
  JOURNAL   J. Biol. Chem. 276 (50), 47575-47582 (2001)
   PUBMED   11590136
REFERENCE   10 (bases 1 to 2745)
  AUTHORS   Sumara,I., Vorlaufer,E., Gieffers,C., Peters,B.H. and Peters,J.M.
  TITLE     Characterization of vertebrate cohesin complexes and their
            regulation in prophase
  JOURNAL   J. Cell Biol. 151 (4), 749-762 (2000)
   PUBMED   11076961
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC041361.1, AC098591.4 and
            CA412233.1.
            
            Summary: The protein encoded by this gene binds to the cohesin
            complex and associates with chromatin through most of the cell
            cycle. The encoded protein may play a role in regulating sister
            chromatid cohesion during mitosis. Two transcript variants encoding
            different isoforms have been found for this gene. [provided by
            RefSeq, May 2010].
            
            Transcript Variant: This variant (3) differs in the 3' UTR and
            lacks several exons in the 3' coding region, compared to variant 1.
            The resulting protein (isoform 3) has a distinct C-terminus and is
            shorter than isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC041361.1, AK098331.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                BC041361.1         5-96
            93-93               AC098591.4         27340-27340         c
            94-2685             BC041361.1         98-2689
            2686-2745           CA412233.1         1-60                c
FEATURES             Location/Qualifiers
     source          1..2745
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p14"
     gene            1..2745
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /note="PDS5, regulator of cohesion maintenance, homolog A
                     (S. cerevisiae)"
                     /db_xref="GeneID:23244"
                     /db_xref="HGNC:29088"
                     /db_xref="MIM:613200"
     exon            1..500
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(20)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145155667"
     variation       complement(34)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:112400722"
     variation       complement(93)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:537353"
     variation       complement(134)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:141371954"
     variation       complement(294)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146606833"
     variation       complement(396..397)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace=""
                     /replace="cgg"
                     /db_xref="dbSNP:377504888"
     exon            501..678
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    508..510
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /note="upstream in-frame stop codon"
     CDS             541..2343
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /note="isoform 3 is encoded by transcript variant 3;
                     sister chromatid cohesion protein PDS5 homolog A; sister
                     chromatid cohesion protein 112; cell
                     proliferation-inducing gene 54 protein"
                     /codon_start=1
                     /product="sister chromatid cohesion protein PDS5 homolog A
                     isoform 3"
                     /protein_id="NP_001093870.1"
                     /db_xref="GI:155030220"
                     /db_xref="CCDS:CCDS54759.1"
                     /db_xref="GeneID:23244"
                     /db_xref="HGNC:29088"
                     /db_xref="MIM:613200"
                     /translation="
MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVVSKSYFTLFL
"
     misc_feature    1717..1827
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q29RF7.1);
                     Region: HEAT"
     variation       complement(588)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201306746"
     variation       complement(621)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370276475"
     variation       complement(626)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200892073"
     variation       complement(678)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183378231"
     exon            679..882
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(693)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373191152"
     variation       complement(735)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190572121"
     variation       complement(741)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368687516"
     variation       complement(799)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201833974"
     variation       complement(813)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376578280"
     variation       complement(863)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372683118"
     variation       complement(866)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369934532"
     exon            883..969
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(948)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376404493"
     exon            970..1067
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(996)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191005753"
     variation       complement(1065)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:186207164"
     exon            1068..1194
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1068)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:77620225"
     variation       complement(1120)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367619204"
     exon            1195..1275
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1207)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370920956"
     variation       complement(1233)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377653620"
     variation       complement(1245)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373483596"
     variation       complement(1257)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369262263"
     variation       complement(1272)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:28449663"
     exon            1276..1416
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1363)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372684647"
     exon            1417..1532
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1437)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375996043"
     variation       complement(1446)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199880029"
     variation       complement(1467)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372830403"
     variation       complement(1506)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368201880"
     variation       complement(1518)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375216497"
     exon            1533..1627
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1614)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187463902"
     exon            1628..1773
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     exon            1774..1925
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1847)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34748316"
     variation       complement(1865)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370580689"
     exon            1926..2039
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1965)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376993510"
     variation       complement(2035)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373353572"
     exon            2040..2121
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2091)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372011026"
     variation       complement(2097)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375379716"
     exon            2122..2170
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     exon            2171..2728
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2229)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200394020"
     variation       complement(2249)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185272845"
     variation       complement(2278)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193075238"
     variation       complement(2317)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371095912"
     variation       complement(2340)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:73229703"
     variation       complement(2361)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188136425"
     variation       complement(2441)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376934899"
     STS             2510..2659
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /standard_name="STS-R02821"
                     /db_xref="UniSTS:70078"
     variation       complement(2518)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377750753"
     variation       complement(2521)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115313226"
     variation       complement(2554)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182513173"
     variation       complement(2634)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191290043"
     polyA_signal    2659..2664
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
     variation       complement(2672..2674)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace=""
                     /replace="tag"
                     /db_xref="dbSNP:377387114"
     variation       complement(2674..2676)
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
                     /replace=""
                     /replace="gta"
                     /db_xref="dbSNP:143322658"
     polyA_site      2681
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
     polyA_site      2728
                     /gene="PDS5A"
                     /gene_synonym="PIG54; SCC-112; SCC112"
ORIGIN      
ggccggcggaggaaggggagggagcgaggagcgcgcgctgctctcgcgtgctctcgcgccgctcgcgtgaccggccggtgtgtgcgcgaggccccggctcccggggcacggacggccgggcgcgcgcctctgcgaggggcgtccgggtccgagtcggcggtccgggccggcgcgaggtgcgtgcgggcgggccgcgggggtcccggacggacacaagcgcacacactcccggaggagccttcgaggctgctcttcctcggccagacggagagcggcactgtctccccgcccagcgctcactcgccccgcgtctccccccgcggcggctgctcctcctcggcaccgccagccccagcgccgctcccgggcgggcgggcggcggcggcggcggcggcgggacccgcggagccgctttgtgtgcagcccgactaggggcggcggcgcaaccacctgacagaggcccgggcgctcgatgcaccttccgcccgcatgaggaggagaggccggtagaggactgtgaaccaaaagttgtcccccaggatggacttcaccgcgcagcccaagcctgccactgccctctgtggcgtcgtgagtgccgacgggaagatcgcttaccctccgggggtaaaagagatcaccgacaagatcaccacggacgagatgatcaaacgcctgaagatggtagtgaaaacctttatggatatggatcaggactcagaagatgaaaaacagcagtatctcccactagccttgcatcttgcatctgaattcttcctcaggaaccccaataaagatgtgcgtctccttgtagcatgttgtttggctgatatctttcgtatctatgccccagaagctccatatacttcccatgataaacttaaggacatatttttgtttattaccagacaattaaaaggtttggaggatacaaagagtccacagtttaatagatacttttatttattagagaatttagcttgggttaaatcatataacatctgctttgaattggaagattgcaatgaaatttttattcagctttttagaactctcttctcagtgatcaacaatagccacaataagaaggtacaaatgcacatgctagatttgatgagttctatcatcatggaaggtgatggagttactcaagaattattggactccattcttattaacctcattcctgcacataagaacttaaataaacagtcctttgaccttgcaaaagtgctattgaaaagaacagtccagactattgaggcatgcattgctaattttttcaatcaagtcctggtgctgggaagatcatcagtaagtgatttgtcagaacatgtatttgatctgattcaggaactttttgctatagatcctcatttattattatccgtcatgccacagcttgaattcaaactaaagagcaatgatggagaagagcgattagctgttgttcgacttctagctaaattgtttggctccaaagattctgatttggcaacacagaatcgtcctctttggcaatgttttcttggacgatttaatgatattcatgttcctgtgagattagaaagtgtgaaatttgccagtcattgtttaatgaatcacccagatttagcgaaggatctcacagaatatttaaaggttagatcacatgatccagaagaagctattcgtcatgatgtcattgttactataataacagctgccaagagggacctggccttagtaaatgatcagctgcttggctttgtaagggaaagaacactggataaacggtggcgagtaagaaaagaagctatgatgggtctggctcagctttataagaaatactgtcttcatggtgaagcaggaaaggaagctgcagagaaagtcagctggataaaggacaaacttctgcatatttattatcagaacagcattgacgacaaactgttggtagagaaaatctttgctcagtatcttgtcccccacaacctggaaacagaagagagaatgaaatgcttatattacttatatgctagtttggatccaaatgctgtaaaagctctcaacgaaatgtggaagtgtcagaacatgcttcggagccatgtacgcgaactattggatttgcacaagcagcctacatcagaggctaactgttctgccatgtttggaaaactgatgaccatagcaaagaatttgcctgaccccgggaaagcacaagattttgtgaagaaatttaaccaggttctcggcgatgatgagaaacttcggtctcagttggagttattaattagcccaacctgttcttgcaaacaagcagatatttgtgtggttagtaaatcatacttcacactttttctctagctttacttacagaaatatgtattttattaaagcctgttttacatacagtgatttgtgtaaatgtaacaatattgtgagctctgaattactttggagtatatctattgtcaagttaattctctatttaccattcactctcagccacattccaggaaaataactaaagaactaagccagggagattggtcttaggaattttacaagataaagtactttgaacttagtagacattcattgagtaatgataagtattttctgaatgcttgtgtacatgtgcattttcttctttcatgtattagaatggaaataatcgtcaataaattagtagtagtaacattgccatatatctggtttcatttacagataaagtaaattcctatctagaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:23244 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:23244 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
            GeneID:23244 -> Biological process: GO:0000910 [cytokinesis] evidence: TAS
            GeneID:23244 -> Biological process: GO:0007067 [mitosis] evidence: IEA
            GeneID:23244 -> Biological process: GO:0008156 [negative regulation of DNA replication] evidence: IMP
            GeneID:23244 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: TAS
            GeneID:23244 -> Cellular component: GO:0000785 [chromatin] evidence: IDA
            GeneID:23244 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:23244 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
            GeneID:23244 -> Cellular component: GO:0005694 [chromosome] evidence: TAS
            GeneID:23244 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:23244 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:23244 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA

by @meso_cacase at DBCLS
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