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2024-05-08 23:52:47, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001098525 3736 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens cytoskeleton associated protein 2 (CKAP2), transcript
variant 2, mRNA.
ACCESSION NM_001098525
VERSION NM_001098525.1 GI:148664200
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3736)
AUTHORS Kang,D.S., Hong,K.M., Park,J. and Bae,C.D.
TITLE Cyclin A regulates a cell-cycle-dependent expression of CKAP2
through phosphorylation of Sp1
JOURNAL Biochem. Biophys. Res. Commun. 420 (4), 822-827 (2012)
PUBMED 22465120
REMARK GeneRIF: GC box was responsible for the cyclic activity of human
CKAP2 promoter through the phosphorylation of Sp1, possibly by
Cyclin A/Cdk complex.
REFERENCE 2 (bases 1 to 3736)
AUTHORS Kim,H.J., Kwon,H.R., Bae,C.D., Park,J. and Hong,K.U.
TITLE Specific primary sequence requirements for Aurora B kinase-mediated
phosphorylation and subcellular localization of TMAP during mitosis
JOURNAL Cell Cycle 9 (10), 2027-2036 (2010)
PUBMED 20458174
REMARK GeneRIF: Findings suggest that the motif surrounding Ser627 ((625)
RRSRRL (630)) is a critical for kinase-substrate recognition and
for regulation of the subcellular localization of TMAP during
mitosis.
REFERENCE 3 (bases 1 to 3736)
AUTHORS Hong,K.U., Kim,H.J., Bae,C.D. and Park,J.
TITLE Characterization of mitosis-specific phosphorylation of
tumor-associated microtubule-associated protein
JOURNAL Exp. Mol. Med. 41 (11), 832-840 (2009)
PUBMED 19641375
REMARK GeneRIF: TMAP is limited to pre-anaphase stages and suggest that
the multiple phosphorylation may not act in concert but serve
diverse functions.
REFERENCE 4 (bases 1 to 3736)
AUTHORS Hong,K.U., Kim,H.J., Kim,H.S., Seong,Y.S., Hong,K.M., Bae,C.D. and
Park,J.
TITLE Cdk1-cyclin B1-mediated phosphorylation of tumor-associated
microtubule-associated protein/cytoskeleton-associated protein 2 in
mitosis
JOURNAL J. Biol. Chem. 284 (24), 16501-16512 (2009)
PUBMED 19369249
REMARK GeneRIF: Cdk1-cyclin B1-mediated phosphorylation of TMAP is
important for and contributes to proper regulation of microtubule
dynamics and establishment of functional bipolar spindles during
mitosis
REFERENCE 5 (bases 1 to 3736)
AUTHORS Seki,A. and Fang,G.
TITLE CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during
mitotic exit
JOURNAL J. Biol. Chem. 282 (20), 15103-15113 (2007)
PUBMED 17376772
REMARK GeneRIF: CKAP2 is a physiological substrate of anaphase-promoting
complex/cyclosome during mitotic exit and that a tight regulation
of the CKAP2 protein level is critical for the normal mitotic
progression.
REFERENCE 6 (bases 1 to 3736)
AUTHORS Bae,C.D., Sung,Y.S., Jeon,S.M., Suh,Y., Yang,H.K., Kim,Y.I.,
Park,K.H., Choi,J., Ahn,G. and Park,J.
TITLE Up-regulation of cytoskeletal-associated protein 2 in primary human
gastric adenocarcinomas
JOURNAL J. Cancer Res. Clin. Oncol. 129 (11), 621-630 (2003)
PUBMED 12942315
REFERENCE 7 (bases 1 to 3736)
AUTHORS Rakhmanaliev,E.R., Klimov,E.A., Kompaniitsev,A.A. and Sulimova,G.E.
TITLE [The structure of the human oncogenesis-associated CKAP2 (LB1)
gene]
JOURNAL Mol. Biol. (Mosk.) 36 (6), 985-989 (2002)
PUBMED 12500535
REMARK GeneRIF: CKAP2 comprises nine exons ranging 70-1442 bp and is about
22 kb in size (regulatory regions included). The CKAP2 promoter
contains CCAAT (-39...-33) rather than the canonical TATA box, and
harbors nine binding sites for six transcription factors
REFERENCE 8 (bases 1 to 3736)
AUTHORS Eichmuller,S., Usener,D., Dummer,R., Stein,A., Thiel,D. and
Schadendorf,D.
TITLE Serological detection of cutaneous T-cell lymphoma-associated
antigens
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 98 (2), 629-634 (2001)
PUBMED 11149944
REFERENCE 9 (bases 1 to 3736)
AUTHORS Udina,I.G., Baranova,A.V., Kompaniitsev,A.A. and Sulimova,G.E.
TITLE [Evolutionarily-conserved gene CKAP2,located in region 13q14.3 of
the human genome, is frequently rearranged in various tumors]
JOURNAL Genetika 37 (1), 120-123 (2001)
PUBMED 11234418
REFERENCE 10 (bases 1 to 3736)
AUTHORS Maouche-Chretien,L., Deleu,N., Badoual,C., Fraissignes,P.,
Berger,R., Gaulard,P., Romeo,P.H. and Leroy-Viard,K.
TITLE Identification of a novel cDNA, encoding a cytoskeletal associated
protein, differentially expressed in diffuse large B cell lymphomas
JOURNAL Oncogene 17 (10), 1245-1251 (1998)
PUBMED 9771967
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BM541375.1, Y15758.1, AY062261.1, AK027103.1 and DB512858.1.
Summary: CKAP2 is a cytoskeleton-associated protein involved in
mitotic progression (Seki and Fang, 2007 [PubMed
17376772]).[supplied by OMIM, Mar 2008].
Transcript Variant: This variant uses an alternate splice acceptor
site at the beginning of the third coding exon resulting in a
protein isoform that is longer by a single amino acid.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: Y15758.1, BC066920.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-107 BM541375.1 6-112
108-1021 Y15758.1 1-914
1022-3457 AY062261.1 940-3375
3458-3458 Y15758.1 3352-3352
3459-3731 AK027103.1 1503-1775
3732-3736 DB512858.1 252-256
FEATURES Location/Qualifiers
source 1..3736
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q14"
gene 1..3736
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/note="cytoskeleton associated protein 2"
/db_xref="GeneID:26586"
/db_xref="HGNC:1990"
/db_xref="MIM:611569"
exon 1..267
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 4
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:187957314"
variation 16
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:4995048"
variation 98
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:114633402"
variation 100
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:369884298"
variation 111
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:192149786"
variation 120
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:369671577"
misc_feature 141..143
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/note="upstream in-frame stop codon"
variation 157
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:370818383"
variation 173
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:375041874"
variation 179
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:368345050"
variation 184
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:372978529"
CDS 198..2249
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/note="isoform 2 is encoded by transcript variant 2;
cytoskeleton-associated protein 2; tumor-associated
microtubule-associated protein; CTCL tumor antigen
se20-10; tumor- and microtubule-associated protein"
/codon_start=1
/product="cytoskeleton-associated protein 2 isoform 2"
/protein_id="NP_001091995.1"
/db_xref="GI:148664201"
/db_xref="CCDS:CCDS41893.1"
/db_xref="GeneID:26586"
/db_xref="HGNC:1990"
/db_xref="MIM:611569"
/translation="
MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRETDAFVCRPNAALCRVYYEADTT
"
misc_feature 1797..1799
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8WWK9.1); phosphorylation site"
misc_feature 1932..1934
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1941..1943
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1980..1982
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8WWK9.1); phosphorylation site"
misc_feature 1983..1985
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1986..1988
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1992..1994
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 2001..2003
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8WWK9.1); phosphorylation site"
variation 216
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:146292755"
exon 268..352
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 282
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:139637131"
variation 293
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:149997663"
variation 316
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:202147843"
variation 325
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:145357920"
exon 353..431
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
exon 432..1300
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 438
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:373545539"
variation 467
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:376367571"
variation 494
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:149189169"
variation 529
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:36022164"
variation 579
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:138583090"
variation 624
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:201217629"
variation 625
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:370214081"
variation 638
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:372390966"
variation 711
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:376545198"
variation 717
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:149254206"
variation 736
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:184495852"
variation 738
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:370906992"
variation 762
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:202229967"
variation 782
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:147763631"
variation 857
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:111764793"
variation 873
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:368615547"
variation 879
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:370863834"
variation 887
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:376206456"
variation 904
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="t"
/db_xref="dbSNP:35975899"
variation 915
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:368402985"
variation 946
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:371667488"
variation 948
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:150312116"
variation 949
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:138054585"
variation 978
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:144431404"
variation 979
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:375956975"
variation 1000
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:367704222"
variation 1014
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:143204885"
variation 1018
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:138768856"
variation 1022
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:7337054"
variation 1029
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:146302747"
variation 1038
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:368666806"
variation 1041
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:200602489"
variation 1054
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:200233086"
variation 1136
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="t"
/db_xref="dbSNP:74085795"
variation 1138
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:141913418"
variation 1164
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:7335867"
variation 1181
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:369584518"
variation 1187
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="t"
/db_xref="dbSNP:373047177"
variation 1199
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:3809374"
variation 1255
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:201553403"
variation 1283
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:375430927"
variation 1288
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:141769986"
exon 1301..1505
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 1322
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:139910485"
variation 1328
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:369722906"
variation 1335
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:373418118"
variation 1339
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:200225546"
variation 1356
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:74085799"
variation 1358
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:200669300"
variation 1361
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:140212356"
variation 1396
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:200158115"
variation 1399
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:370145315"
variation 1408
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:201326864"
variation 1471
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:373389022"
exon 1506..1676
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 1510
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:145609331"
variation 1513
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:147773280"
variation 1518
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:148820633"
variation 1527
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:192868791"
variation 1528
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:377639183"
variation 1550
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="t"
/db_xref="dbSNP:371432306"
variation 1561
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:147937279"
variation 1606
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:201479437"
variation 1623
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:143514154"
exon 1677..1746
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 1692
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:150954069"
variation 1695
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:140760250"
variation 1704
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:117024941"
variation 1715
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:138633500"
variation 1721..1722
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace=""
/replace="c"
/db_xref="dbSNP:34902853"
variation 1726
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:375816758"
exon 1747..2002
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 1749
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:41292820"
variation 1751
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:112465889"
variation 1755
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:200189892"
variation 1777
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:377566863"
variation 1810
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:369352268"
variation 1867
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:145551694"
variation 1900
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:373740676"
variation 1918
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:201305173"
variation 1949
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:377669665"
variation 1964
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:368021748"
variation 1987
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:138265024"
exon 2003..3736
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 2037
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:200166848"
variation 2051
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:41292822"
variation 2055
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:376894890"
variation 2069
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:149052925"
variation 2083
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:370416292"
variation 2086
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:73186408"
variation 2089
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:373578702"
variation 2171
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:34624748"
variation 2174
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:147510699"
variation 2199
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:140040526"
variation 2220
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:202031498"
variation 2240
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:34494025"
variation 2273
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:201310249"
variation 2274
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:201018318"
variation 2278
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:199938465"
variation 2326..2327
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace=""
/replace="g"
/db_xref="dbSNP:35893582"
STS 2356..2659
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/standard_name="RH106549"
/db_xref="UniSTS:209623"
variation 2398
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:141447887"
variation 2459
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:115036651"
variation 2465
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:74850630"
variation 2667
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:192600543"
variation 2715
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:78029237"
variation 2849
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:374584816"
variation 2962
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:184535702"
variation 2992
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:116458749"
variation 3224
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:78524889"
variation 3295
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:189212554"
variation 3388
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:202188690"
variation 3452
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:9379"
variation 3596
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:41292824"
variation 3610
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:181058098"
ORIGIN
accggccccggcaactgcagtccaggctccgcctccctacgcccattggcttattcaattcacgcaggaaccaatgggcggagacggcagccgcgccgtctgacggcttagccgcggtgcagactgcggcggcggtggtctgaggaagttctatcttggcgctaaagcggagacgcatcccccgacccgaggctacgatgagcacaccggccgtgccccaggacctgcagctgcccccgagtcagagggcgcagtccgcattcaaagagcaaagaagacaaaaactcaaggaacatctgttgagaagaaaaacgctttttgcatacaagcaggaaaatgagatgttatccagtagtagagatcagagagttgtgacatctgaggaccaagttcaagaagggactaaagtgctgaaacttaaaacaaaaatggctgataaagaaaacatgaagagacctgcagagagcaaaaataatacagtggtggggaaacattgtattcctttaaaaccttcaaatgaactaaccaattcaactgtagtaattgacacacataaacctaaggatagtaatcaaactccgcatttgttactaactgaagatgatccccaaagtcaacatatgacattaagccaggcatttcaccttaaaaacaatagtaaaaagaaacaaatgactacagaaaaacaaaagcaagatgctaacatgcccaagaaacctgtgcttggatcttatcgtggccagattgttcagtctaagattaattcatttagaaaacctctacaagtcaaagatgagagttctgcagcaacaaagaaactttcagccactatacctaaagccacaaaacctcagcctgtaaacaccagcagtgtaacagtgaaaagtaatagatcctccaatatgactgccactactaaatttgtgagcactacatctcagaacacacaacttgtgcgacctcctattagaagtcatcacagtaatacccgggacactgtgaaacaaggcatcagtagaacttctgccaatgttacaatccggaaagggcctcatgaaaaagaactattacaatcaaaaacagctttatctagtgtcaaaaccagttcttctcaaggtataataagaaataagactctatcaagatccatagcatctgaagttatagccaggcctgcttcattgtctaatgataaactgatggaaaagtcagagcccgttgaccagcgaagacatactgcaggaaaagcaattgttgatagtagatcagctcagcccaaagaaacctcggaagagagaaaagctcgtctgagtgagtggaaagctggcaaaggaagagtgctaaaaaggccccctaattcagtagttactcagcatgagcctgcaggacaaaatgaaaaaccagttgggtctttttggactaccatggcagaagaagatgaacaaagattatttactgaaaaagtaaacaacacattttctgaatgcctgaacttgattaatgagggatgtccaaaagaagatatactggtcacactgaatgacctgattaaaaatattccagatgccaaaaagcttgttaagtattggatatgtcttgcacttattgaaccaatcacaagtcctattgaaaatattattgcaatctatgagaaagccattctggcaggggctcagcctattgaagagatgcgacacacgattgtagatattctaacaatgaagagtcaagaaaaagctaatttaggagaaaatatggagaagtcttgtgcaagcaaggaagaagtcaaagaagtcagtattgaagatacaggtgttgatgtagatccagaaaaactggaaatggagagtaaacttcatagaaatttgctatttcaagattgtgaaaaagagcaagacaacaaaacaaaagatccaacccatgatgttaaaacccccaatacagaaacgaggacaagttgcttaattaaatataatgtgtctactacgccatacttgcaaagtgtgaaaaaaaaggtgcagtttgatggaacaaattccgcatttaaagagctgaagtttttaacaccagtgagacgttctcgacgtcttcaagagaaaacttctaaattgccagatatgttaaaagatcattatccttgtgtgtcttcattggaacagctaacggagttgggaagagaaactgatgcttttgtatgccgccctaatgcagcactgtgccgggtgtactatgaggctgatacaacataagagaaataaagctctgttagggaatggggtttttattatttgtggggtgttttgttttgagtagctttatattgctcttaggtctggagttggccatgtacctatgtatcctaagcattcacggcagtgagctcctttactaacattcatgttatggcaagagttgtcctctacattggaaagctaatcctaccttgtcagtttcaaccaactgagttttttctttaagaaaggtaaattttgtcagctagtttactatgttccttgaatataaacaggttataatactaccctgttcactttactaaatataagtacagtaatgatgcataattagaaaatgaggtattctaggtaaaatgtatgtttgccttgacatgtttttaaaagttatgatgtacctccctgcctttaaacagaatacttttttcttttttttggcctttctcagattagtcaaaaattctatagaatgactcacttcgaatactaagacacaggaggtttagcctgctttcttaccaaattcatgttacccagacttgtgttctcttgcgtcccttggactgcctgttgattgatggaaagtgtctgcactgacacttttcgtcagtagtctgtagtttcgtggcctcttttgattataactggggtcaccaagaaggtttacttaattaaataccgcatttctaagagaagatactttgtgtaagaaaagatgccacatttagtggtttaacttttgtaacttcacttgatagtttttaagcaattagaatggagttagggaaagaacatatcatactgaacaaatgtcattctagtttagatagcatttctaagataactgatactaatacttgttttcttccctataacataaaaaacttcactgttaagtcatgtcccttgaaacatgatagttacatacacagttttctctccacacataaataacaccactaaagttgttttgtaaggttccaaactaatatggcatatatcaactctacagtttcaaataaatgactttttaattgtaaaagattagttgaaaaactgtatgaatgtgaagatcacatgcttagtcatttttatgttcattccactttgtatatcttttctatttattgacttctcatgttctagagagtaggacttttattccgtgtacctgatatatatacaattaaaatatctgtgtaattatgttttaatgaagtttatttcaacagatattttatgaaatgcagtttaaccacagtgaatgaattttagctttgcttttgaaatacattgtaagatttgacttgaggtttttgacacttaagtacatgcttaatgatatattttcaaaagtcatcagtctacttacataaactttacctaatttttttcactttaacaaaaacataactatgcccttgttttttcatactttgacccaaaatatgccattttgaaataaaatttaagctttgatacac
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:26586 -> Biological process: GO:0000281 [mitotic cytokinesis] evidence: IGI
GeneID:26586 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:26586 -> Biological process: GO:0007026 [negative regulation of microtubule depolymerization] evidence: IEA
GeneID:26586 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IGI
GeneID:26586 -> Cellular component: GO:0000922 [spindle pole] evidence: IEA
GeneID:26586 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:26586 -> Cellular component: GO:0005813 [centrosome] evidence: IDA
GeneID:26586 -> Cellular component: GO:0005881 [cytoplasmic microtubule] evidence: IDA
GeneID:26586 -> Cellular component: GO:0015630 [microtubule cytoskeleton] evidence: IDA
by
@meso_cacase at
DBCLS
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