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2024-03-29 17:42:54, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001098522            1719 bp    mRNA    linear   PRI 15-JUL-2013
DEFINITION  Homo sapiens HIV-1 Tat interactive protein 2, 30kDa (HTATIP2),
            transcript variant 4, mRNA.
ACCESSION   NM_001098522
VERSION     NM_001098522.1  GI:148728171
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1719)
  AUTHORS   Li,A., Zhang,C., Gao,S., Chen,F., Yang,C., Luo,R. and Xiao,H.
  TITLE     TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and
            promotes lung adenocarcinogenesis in mice
  JOURNAL   Oncogene 32 (18), 2273-2281 (2013)
   PUBMED   22733137
  REMARK    GeneRIF: TIP30 acts as a crucial regulator in suppressing
            cytoplasmic and nuclear EGFR signaling in the lung.TIP30 functions
            as a tumor suppressor to inhibit EGFR cytoplasmic and nuclear
            signaling and suppress adenocarcinogenesis in the lung.
REFERENCE   2  (bases 1 to 1719)
  AUTHORS   Huang,Q.D., Hu,X.Q., Wan,L., Gao,G.H., Zheng,S.R., You,J. and
            Guo,G.L.
  TITLE     [Clinical significance of CC3/TIP30 expression in breast carcinoma
            and its correlation with HER-2/neu]
  JOURNAL   Zhonghua Wai Ke Za Zhi 50 (1), 57-61 (2012)
   PUBMED   22490293
  REMARK    GeneRIF: The loss of CC3/TIP30 is related to occurrence and
            development in breast cancer, suggesting early onset of metastasis
            and recurrence.
REFERENCE   3  (bases 1 to 1719)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS ONE 7 (12), E51954 (2012)
   PUBMED   23251661
REFERENCE   4  (bases 1 to 1719)
  AUTHORS   Liu,D.C. and Yang,Z.L.
  TITLE     Clinicopathologic significance of minichromosome maintenance
            protein 2 and Tat-interacting protein 30 expression in benign and
            malignant lesions of the gallbladder
  JOURNAL   Hum. Pathol. 42 (11), 1676-1683 (2011)
   PUBMED   21543106
  REMARK    GeneRIF: overexpression of MCM2 or loss of expression of
            Tat-interacting protein 30 is closely related to carcinogenesis,
            progression, biological behavior, and prognosis of gallbladder
            adenocarcinoma.
REFERENCE   5  (bases 1 to 1719)
  AUTHORS   Zhang,C., Li,A., Gao,S., Zhang,X. and Xiao,H.
  TITLE     The TIP30 protein complex, arachidonic acid and coenzyme A are
            required for vesicle membrane fusion
  JOURNAL   PLoS ONE 6 (6), E21233 (2011)
   PUBMED   21731680
  REMARK    GeneRIF: The TIP30 complex facilitates biological membrane fusion
            through modification of phosphatidic acid on membranes.
REFERENCE   6  (bases 1 to 1719)
  AUTHORS   Xiao,H., Palhan,V., Yang,Y. and Roeder,R.G.
  TITLE     TIP30 has an intrinsic kinase activity required for up-regulation
            of a subset of apoptotic genes
  JOURNAL   EMBO J. 19 (5), 956-963 (2000)
   PUBMED   10698937
REFERENCE   7  (bases 1 to 1719)
  AUTHORS   Whitman,S., Wang,X., Shalaby,R. and Shtivelman,E.
  TITLE     Alternatively spliced products CC3 and TC3 have opposing effects on
            apoptosis
  JOURNAL   Mol. Cell. Biol. 20 (2), 583-593 (2000)
   PUBMED   10611237
REFERENCE   8  (bases 1 to 1719)
  AUTHORS   Baker,M.E.
  TITLE     TIP30, a cofactor for HIV-1 Tat-activated transcription, is
            homologous to short-chain dehydrogenases/reductases
  JOURNAL   Curr. Biol. 9 (13), R471 (1999)
   PUBMED   10395547
REFERENCE   9  (bases 1 to 1719)
  AUTHORS   Xiao,H., Tao,Y., Greenblatt,J. and Roeder,R.G.
  TITLE     A cofactor, TIP30, specifically enhances HIV-1 Tat-activated
            transcription
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 95 (5), 2146-2151 (1998)
   PUBMED   9482853
REFERENCE   10 (bases 1 to 1719)
  AUTHORS   Shtivelman,E.
  TITLE     A link between metastasis and resistance to apoptosis of variant
            small cell lung carcinoma
  JOURNAL   Oncogene 14 (18), 2167-2173 (1997)
   PUBMED   9174052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI193677.1, AK222969.1 and BC015358.2.
            
            Transcript Variant: This variant (4) has an alternate 5' end and
            differs in the 5' UTR, compared to variant 1. These differences
            cause translation initiation at a downstream AUG and an isoform (b,
            also known as CC3) with a shorter N-terminus compared to isoform a.
            Variants 2, 3 and 4 encode the same isoform.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC015358.2, AK222969.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-566               AI193677.1         1-566
            567-1684            AK222969.1         241-1358
            1685-1719           BC015358.2         1381-1415
FEATURES             Location/Qualifiers
     source          1..1719
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.1"
     gene            1..1719
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /note="HIV-1 Tat interactive protein 2, 30kDa"
                     /db_xref="GeneID:10553"
                     /db_xref="HGNC:16637"
                     /db_xref="MIM:605628"
     exon            1..576
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /inference="alignment:Splign:1.39.8"
     variation       123
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:115952677"
     variation       190
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:79849373"
     variation       204
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10437608"
     variation       218
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79794774"
     variation       219
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:142699710"
     variation       232
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114719875"
     misc_feature    340..342
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /note="upstream in-frame stop codon"
     variation       346
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371982853"
     variation       377
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199846818"
     CDS             382..1110
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /EC_number="1.1.1.-"
                     /note="isoform b is encoded by transcript variant 4; short
                     chain dehydrogenase/reductase family 44U, member 1;
                     Tat-interacting protein (30kD); oxidoreductase HTATIP2;
                     HIV-1 TAT-interactive protein 2; 30 kDa HIV-1
                     TAT-interacting protein"
                     /codon_start=1
                     /product="oxidoreductase HTATIP2 isoform b"
                     /protein_id="NP_001091992.1"
                     /db_xref="GI:148728172"
                     /db_xref="CCDS:CCDS7852.1"
                     /db_xref="GeneID:10553"
                     /db_xref="HGNC:16637"
                     /db_xref="MIM:605628"
                     /translation="
MAETEALSKLREDFRMQNKSVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQEVVDFEKLDDYASAFQGHDVGFCCLGTTRGKAGAEGFVRVDRDYVLKSAELAKAGGCKHFNLLSSKGADKSSNFLYLQVKGEVEAKVEELKFDRYSVFRPGVLLCDRQESRPGEWLVRKFFGSLPDSWASGHSVPVVTVVRAMLNNVVRPRDKQMELLENKAIHDLGKAHGSLKP
"
     misc_feature    436..1074
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /note="CC3(TIP30)-like, atypical (a) SDRs; Region:
                     CC3_like_SDR_a; cd05250"
                     /db_xref="CDD:187560"
     misc_feature    448..>891
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /note="NADH(P)-binding; Region: NAD_binding_10; pfam13460"
                     /db_xref="CDD:205638"
     misc_feature    order(454..456,460..471,535..540,595..597,652..663,
                     700..702,712..714,769..777,808..810,820..822,880..891)
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187560"
     misc_feature    order(703..705,775..777,808..810,820..822)
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /note="active site"
                     /db_xref="CDD:187560"
     variation       386
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369625277"
     variation       471
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191533610"
     variation       490
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202128953"
     variation       506
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200846453"
     variation       525
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145143466"
     variation       529
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200473579"
     variation       540
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145549108"
     exon            577..684
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /inference="alignment:Splign:1.39.8"
     variation       615
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112368564"
     variation       623
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144136689"
     variation       634
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146530848"
     variation       639
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77126933"
     variation       640
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:14273"
     variation       646
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140788394"
     variation       655
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377269888"
     variation       677
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143928186"
     variation       678
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200863409"
     variation       683
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148194087"
     exon            685..822
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /inference="alignment:Splign:1.39.8"
     variation       713
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140080675"
     variation       717
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140165037"
     variation       742
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:181081777"
     variation       763
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377524639"
     variation       771
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150327548"
     variation       785
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:370929399"
     variation       792
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141995111"
     exon            823..884
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /inference="alignment:Splign:1.39.8"
     variation       838
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138879906"
     variation       862
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376468659"
     variation       865
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370076424"
     exon            885..1688
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /inference="alignment:Splign:1.39.8"
     variation       888
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143261552"
     variation       940
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051776"
     variation       961..962
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35285540"
     variation       972
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3824886"
     variation       977
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:79296772"
     variation       984
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:142077207"
     variation       997
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144100738"
     variation       1002
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373986235"
     variation       1062
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187804828"
     variation       1066
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:14222"
     variation       1074
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200003351"
     variation       1089
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202065100"
     variation       1108
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:370774686"
     variation       1116
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3781679"
     variation       1246
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372324685"
     variation       1299
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191247504"
     variation       1382
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:183794581"
     variation       1420
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375554086"
     variation       1494
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:16906210"
     variation       1527
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369175509"
     STS             1529..1668
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /standard_name="G29234"
                     /db_xref="UniSTS:63559"
     variation       1573
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:188466553"
     variation       1613
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77228546"
     polyA_signal    1657..1662
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
     polyA_signal    1665..1670
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
     polyA_site      1688
                     /gene="HTATIP2"
                     /gene_synonym="CC3; SDR44U1; TIP30"
ORIGIN      
gcggccgccctgctcctgctgcgtcgtgaggacccggggccgggggctggccccaggtaacccctccgcgtatgggaccgagctgggccaggtctcctggccgggccggggataccgtggggtatgcccagtgatgccagcagcttgtggcacctgggcgcaccctccagctcgggccccttccgatgggtctgctggctcaggtgcgggcgatggccggggagccgcgccccgcacgtgactcagcactttccccagagcccggactgcggagaacaatatcctcctccctaacagataaacagcccttgttcctcgggataaggactggcagtcccctgacaccctaagaccggcatctgtcgatgttatttccccagcatggccgaaacagaagccctgtcgaagcttcgggaagacttcaggatgcagaataaatccgtctttattttgggcgccagcggagaaaccggcagagtgctcttaaaggaaatcctggagcagggcctgttttccaaagtcacgctcattggccggaggaagctcaccttcgacgaggaagcttataaaaatgtgaatcaagaagtggtggactttgaaaagttggatgactacgcctctgcctttcaaggtcatgatgttggattctgttgcctgggtaccaccagagggaaagctggggcggagggatttgttcgtgttgaccgagattatgtgctgaagtctgcagagctggcaaaagctggagggtgcaaacatttcaacttgctatcctctaaaggagctgataaatcaagcaattttttatatctacaagttaagggagaagtagaagccaaggttgaagaattaaaatttgatcgttactctgtatttaggcctggagttctgttatgtgataggcaagaatctcgcccaggtgaatggctggttagaaagttctttggctccttaccagactcttgggccagtgggcattctgtgcctgtggtgaccgtggttagagcaatgctgaacaatgtggtgagaccaagagacaagcagatggaactgctggagaacaaggccatccatgacctggggaaagcgcatggctctctcaagccatgaccacattggagaaatggtttttattgtcaaccttaacacccatcaccaaatcggtaatttcagggtctaaaaaaagtcagcatgttttaactttgttgttttactatcctcaggcatccattccaatcaagaaatgatggtgctctgcatcagtggttcagagcctggttatacatatagatcactcagggagctttggaaaaataaagatttgtcagccctatctcaaacttgaatcaaaatttctggggtgtgggcacaataatctgtaattttctttgtttatacttcccctgatgccactggttccgatgccactggctggggggcctgctttgaaatgcttgtctgcagagtcacagcagccatgaaaaccttatgaccgtgcaaatgagctctgctctaaaattgttgacattcatgtctctgagttacaaaagtgctaattcactacatgtaattgtgtaagtaaacattgtgcctttactacttctttatgtaatagaagttatatacctaagcttatataatacatggggaggattaaataaaggaataaagatgaatggacaactcctaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:10553 -> Molecular function: GO:0003713 [transcription coactivator activity] evidence: TAS
            GeneID:10553 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:10553 -> Molecular function: GO:0016491 [oxidoreductase activity] evidence: IEA
            GeneID:10553 -> Biological process: GO:0001525 [angiogenesis] evidence: IEA
            GeneID:10553 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: TAS
            GeneID:10553 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
            GeneID:10553 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
            GeneID:10553 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
            GeneID:10553 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: TAS
            GeneID:10553 -> Biological process: GO:0045765 [regulation of angiogenesis] evidence: IDA
            GeneID:10553 -> Biological process: GO:0051170 [nuclear import] evidence: IDA
            GeneID:10553 -> Cellular component: GO:0005634 [nucleus] evidence: TAS
            GeneID:10553 -> Cellular component: GO:0005635 [nuclear envelope] evidence: IDA
            GeneID:10553 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_001091992 -> EC 1.1.1.-

by @meso_cacase at DBCLS
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