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2024-04-20 08:33:10, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001066 3682 bp mRNA linear PRI 15-JUL-2013
DEFINITION Homo sapiens tumor necrosis factor receptor superfamily, member 1B
(TNFRSF1B), mRNA.
ACCESSION NM_001066
VERSION NM_001066.2 GI:23312365
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3682)
AUTHORS Wammes,L.J., Wiria,A.E., Toenhake,C.G., Hamid,F., Liu,K.Y.,
Suryani,H., Kaisar,M.M., Verweij,J.J., Sartono,E., Supali,T.,
Smits,H.H., Luty,A.J. and Yazdanbakhsh,M.
TITLE Asymptomatic plasmodial infection is associated with increased
tumor necrosis factor receptor II-expressing regulatory T cells and
suppressed type 2 immune responses
JOURNAL J. Infect. Dis. 207 (10), 1590-1599 (2013)
PUBMED 23408847
REMARK GeneRIF: In vivo malaria-induced TNF upregulates TNFRII on
regulatory T-cells, which might increase their activity and
therefore more effectively prevent in fl ammation.
REFERENCE 2 (bases 1 to 3682)
AUTHORS Lopatnikova,J.A., Vasilyev,F.F., Alshevskaya,A.A. and Sennikov,S.V.
TITLE Quantitative flow cytometric analysis of expression of tumor
necrosis factor receptor types I and II on mononuclear cells
JOURNAL J. Recept. Signal Transduct. Res. 33 (1), 49-55 (2013)
PUBMED 23316846
REMARK GeneRIF: Application of the protocol-identified differences in the
percentage of cells that expressed TNFRs, as well as the absolute
number of receptors per cell, among different subpopulations of
PBMCs, and between PBMCs cultured with and without LPS.
REFERENCE 3 (bases 1 to 3682)
AUTHORS Chakrabarti,S. and Davidge,S.T.
TITLE Estradiol modulates tumor necrosis factor-induced endothelial
inflammation: role of tumor necrosis factor receptor 2
JOURNAL J. Vasc. Res. 50 (1), 21-34 (2013)
PUBMED 23095497
REMARK GeneRIF: Suggest the effects of chronic E(2) to be dependent on
TNFR2 signaling in endothelial cells.
REFERENCE 4 (bases 1 to 3682)
AUTHORS McTiernan,C.F., Ramani,R., Burkhead,B. and McNamara,D.
TITLE The methionine 196 arginine polymorphism of the TNF receptor 2 gene
(TNFRSF1B) is not associated with worse outcomes in heart failure
JOURNAL Cytokine 60 (3), 838-842 (2012)
PUBMED 22921902
REMARK GeneRIF: The TNFRSF1B 587G allele is not associated with the
severity of heart failure phenotype or clinical outcomes in
patients with chronic congestive heart failure.
REFERENCE 5 (bases 1 to 3682)
AUTHORS Agnello,E., Malfi,G., Costantino,A.M., Massarenti,P., Pugliese,M.,
Fortunati,N., Catalano,M.G. and Palmo,A.
TITLE Tumour necrosis factor alpha and oxidative stress as maintaining
factors in the evolution of anorexia nervosa
JOURNAL Eat Weight Disord 17 (3), E194-E199 (2012)
PUBMED 23086255
REMARK GeneRIF: TNF-R75 was higher in anorexia nervosa patients with
duration of disease longer than one year as compared to controls
and patients with shorter duration. TNF-R75 inversely correlated
with BMI and directly with disease duration.
REFERENCE 6 (bases 1 to 3682)
AUTHORS Pocsik,E., Higuchi,M. and Aggarwal,B.B.
TITLE Down-modulation of cell surface expression of p80 form of the tumor
necrosis factor receptor by human immunodeficiency virus-1 tat gene
JOURNAL Lymphokine Cytokine Res. 11 (6), 317-325 (1992)
PUBMED 1335762
REFERENCE 7 (bases 1 to 3682)
AUTHORS Pennica,D., Lam,V.T., Mize,N.K., Weber,R.F., Lewis,M., Fendly,B.M.,
Lipari,M.T. and Goeddel,D.V.
TITLE Biochemical properties of the 75-kDa tumor necrosis factor
receptor. Characterization of ligand binding, internalization, and
receptor phosphorylation
JOURNAL J. Biol. Chem. 267 (29), 21172-21178 (1992)
PUBMED 1328224
REFERENCE 8 (bases 1 to 3682)
AUTHORS Ryffel,B., Brockhaus,M., Greiner,B., Mihatsch,M.J. and Gudat,F.
TITLE Tumour necrosis factor receptor distribution in human lymphoid
tissue
JOURNAL Immunology 74 (3), 446-452 (1991)
PUBMED 1663076
REFERENCE 9 (bases 1 to 3682)
AUTHORS Kemper,O., Derre,J., Cherif,D., Engelmann,H., Wallach,D. and
Berger,R.
TITLE The gene for the type II (p75) tumor necrosis factor receptor
(TNF-RII) is localized on band 1p36.2-p36.3
JOURNAL Hum. Genet. 87 (5), 623-624 (1991)
PUBMED 1655619
REFERENCE 10 (bases 1 to 3682)
AUTHORS Bost,R. and Hostein,J.
TITLE [Gastroduodenal reflux and non-ulcerous dyspepsia. Is it an
accidental association?]
JOURNAL Ann Gastroenterol Hepatol (Paris) 27 (4), 191-192 (1991)
PUBMED 1929203
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from M32315.1.
This sequence is a reference standard in the RefSeqGene project.
On Sep 25, 2002 this sequence version replaced gi:4507576.
Summary: The protein encoded by this gene is a member of the
TNF-receptor superfamily. This protein and TNF-receptor 1 form a
heterocomplex that mediates the recruitment of two anti-apoptotic
proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase
activity. The function of IAPs in TNF-receptor signalling is
unknown, however, c-IAP1 is thought to potentiate TNF-induced
apoptosis by the ubiquitination and degradation of
TNF-receptor-associated factor 2, which mediates anti-apoptotic
signals. Knockout studies in mice also suggest a role of this
protein in protecting neurons from apoptosis by stimulating
antioxidative pathways. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: M32315.1, M55994.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025083 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
FEATURES Location/Qualifiers
source 1..3682
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p36.22"
gene 1..3682
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="tumor necrosis factor receptor superfamily, member
1B"
/db_xref="GeneID:7133"
/db_xref="HGNC:11917"
/db_xref="HPRD:01862"
/db_xref="MIM:191191"
exon 1..167
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 6
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:375496944"
variation 15
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:5745949"
variation 31
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:5745950"
variation 61..62
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="gcgagggc"
/db_xref="dbSNP:5745951"
CDS 90..1475
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="tumor necrosis factor beta receptor; tumor necrosis
factor binding protein 2; soluble TNFR1B variant 1; p75
TNF receptor; TNF-R2; TNF-RII; p80 TNF-alpha receptor;
tumor necrosis factor receptor 2; tumor necrosis factor
receptor type II"
/codon_start=1
/product="tumor necrosis factor receptor superfamily
member 1B precursor"
/protein_id="NP_001057.1"
/db_xref="GI:4507577"
/db_xref="CCDS:CCDS145.1"
/db_xref="GeneID:7133"
/db_xref="HGNC:11917"
/db_xref="HPRD:01862"
/db_xref="MIM:191191"
/translation="
MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
"
sig_peptide 90..155
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
mat_peptide 156..1472
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/product="tumor necrosis factor receptor superfamily
member 1B"
misc_feature 204..317
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P20333.3);
Region: TNFR-Cys 1"
misc_feature 207..512
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="Tumor necrosis factor receptor (TNFR) domain;
superfamily of TNF-like receptor domains. When bound to
TNF-like cytokines, TNFRs trigger multiple signal
transduction pathways, they are involved in inflammation
response, apoptosis, autoimmunity and...; Region: TNFR;
cd00185"
/db_xref="CDD:29147"
misc_feature order(207..212,336..338,369..371,399..401,465..467,
498..500)
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="antiparallel homodimerization interface
[polypeptide binding]; other site"
/db_xref="CDD:29147"
misc_feature order(219..221,252..254,264..266,270..272,309..311,
318..320,348..350)
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="parallel homodimerization interface [polypeptide
binding]; other site"
/db_xref="CDD:29147"
misc_feature order(252..281,306..320,420..428)
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="protein binding site [polypeptide binding]; other
site"
/db_xref="CDD:29147"
misc_feature 318..443
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P20333.3);
Region: TNFR-Cys 2"
misc_feature order(345..350,366..374)
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="50's loop TNF binding site; other site"
/db_xref="CDD:29147"
misc_feature 444..575
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P20333.3);
Region: TNFR-Cys 3"
misc_feature order(465..467,498..512)
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="90's loop TNF binding site; other site"
/db_xref="CDD:29147"
misc_feature 513..>689
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="Tumor necrosis factor receptor (TNFR) domain;
superfamily of TNF-like receptor domains. When bound to
TNF-like cytokines, TNFRs trigger multiple signal
transduction pathways, they are involved in inflammation
response, apoptosis, autoimmunity and...; Region: TNFR;
cl12111"
/db_xref="CDD:209448"
misc_feature order(513..539,564..578,666..674)
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="protein binding site [polypeptide binding]; other
site"
/db_xref="CDD:29147"
misc_feature order(522..524,528..530,567..569,576..578,606..608)
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="parallel homodimerization interface [polypeptide
binding]; other site"
/db_xref="CDD:29147"
misc_feature 576..692
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P20333.3);
Region: TNFR-Cys 4"
misc_feature order(603..608,624..632)
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/note="50's loop TNF binding site; other site"
/db_xref="CDD:29147"
misc_feature 861..950
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P20333.3);
transmembrane region"
misc_feature 1395..1397
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
variation 120
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:113538181"
exon 168..267
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 172
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:142907823"
variation 178
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:183755458"
variation 191
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:373387104"
variation 197
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:377349339"
variation 257
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:945439"
variation 262
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:139221787"
variation 263
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:149960043"
variation 265
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:140531887"
exon 268..396
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 299
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:147703074"
variation 395
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:142297196"
exon 397..546
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 425
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:150483691"
variation 468
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:138462821"
variation 469
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:375442414"
variation 506
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:145097690"
variation 515
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:201949042"
exon 547..640
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 576
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:373216188"
variation 592
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:201574750"
variation 605
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:141628211"
variation 617
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:377401769"
variation 632
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:2275415"
exon 641..876
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 648
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:2228494"
variation 654
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:200254914"
variation 676
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:1061622"
variation 697
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:199873050"
variation 702
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:201545665"
variation 708
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:140857317"
variation 760
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:145736387"
variation 783
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:5746026"
variation 795
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:5746027"
variation 805
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:150329910"
variation 822
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:375948624"
variation 857
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:146983380"
variation 864
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:199974127"
exon 877..954
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 880
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:2229700"
variation 894
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:17879042"
variation 909
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:61761336"
variation 944
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:201648206"
variation 948
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:192393562"
exon 955..989
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 973
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:5746032"
exon 990..1194
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 991
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:17883432"
variation 1004
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:369209421"
variation 1008
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:199931640"
variation 1018
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:373401765"
variation 1031
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:375369071"
variation 1042
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:116544657"
variation 1058
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:77990239"
variation 1061
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:201872077"
variation 1076
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:368749492"
variation 1091
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:372975213"
variation 1123
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:377693214"
variation 1146
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:112914333"
variation 1171
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:372228157"
variation 1174
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:369918901"
exon 1195..3675
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/inference="alignment:Splign:1.39.8"
variation 1198
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:75299314"
variation 1213
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:55925819"
variation 1273
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:370414826"
variation 1281
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:142879753"
variation 1291
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:376576479"
variation 1325
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:139665575"
variation 1343
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:150855008"
variation 1357
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:370292777"
variation 1364
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:149512902"
variation 1381
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:373722040"
variation 1397
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:368698604"
variation 1410
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:200600328"
variation 1425
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:371439340"
variation 1444
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:200538351"
variation 1461
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:375627878"
variation 1482
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:368365494"
variation 1483
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:371983819"
variation 1495
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:199689616"
variation 1497
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:150675043"
variation 1498
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:368107139"
variation 1500
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:371676482"
variation 1514
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:201385323"
variation 1517
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:374945013"
variation 1537
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:370508215"
STS 1561..1761
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/standard_name="SHGC-31494"
/db_xref="UniSTS:31588"
STS 1571..1762
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/standard_name="RH63769"
/db_xref="UniSTS:14599"
variation 1595
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:186736505"
variation 1613
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:200873417"
variation 1650
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="t"
/db_xref="dbSNP:374272314"
variation 1662
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:368441565"
variation 1663
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:1061624"
variation 1668
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:5030792"
variation 1690
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:3397"
variation 1723
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:114236595"
STS 1747..1953
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/standard_name="G15915"
/db_xref="UniSTS:32079"
variation 1785
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:368738070"
variation 1842
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="gttt"
/db_xref="dbSNP:17883663"
variation 1845..1846
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="gttt"
/db_xref="dbSNP:5746064"
variation 1862
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:5746065"
variation 1900
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:10157774"
variation 1928
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:5746066"
variation 1947
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:5746067"
variation 1953
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:5746068"
variation 1971
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:367861844"
variation 1996
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:17880792"
variation 2029
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:191982398"
variation 2049
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:17881445"
variation 2082
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:370156484"
variation 2104
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:17880332"
variation 2135
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:5746069"
variation 2136
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:187438259"
STS 2215..2355
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/standard_name="PMC156606P3"
/db_xref="UniSTS:271410"
variation 2234
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:372210559"
variation 2241
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:377063779"
variation 2248
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:189604514"
variation 2297
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:182211706"
variation 2312
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:186856234"
variation 2313
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:5746070"
variation 2339..2340
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="g"
/db_xref="dbSNP:71568396"
variation 2349
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:374205228"
variation 2369..2370
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="a"
/db_xref="dbSNP:55651536"
variation 2397
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:1061628"
variation 2421..2422
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="tgaa"
/db_xref="dbSNP:5746071"
variation 2422..2423
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="tgaa"
/db_xref="dbSNP:373828938"
variation 2452
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:369926083"
variation 2464
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:139456075"
variation 2555
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:6668561"
variation 2583
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:77552668"
variation 2607
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:61774891"
variation 2623
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:113401157"
variation 2652
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:5746072"
variation 2660
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="g"
/db_xref="dbSNP:183385861"
variation 2740
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:11807940"
variation 2784
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:117721591"
variation 2785
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:17880872"
variation 2786
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:17881461"
variation 2830
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:148699600"
variation 2893
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:13306717"
variation 2897
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:1061631"
variation 2932
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:376320857"
STS 2968..3673
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/standard_name="TNFRSF1B_287"
/db_xref="UniSTS:277829"
variation 2969
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:1800621"
variation 2976
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:17884182"
variation 2995
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="g"
/replace="t"
/db_xref="dbSNP:113865581"
variation 3028
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1061642"
variation 3035
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="c"
/replace="t"
/db_xref="dbSNP:5746073"
variation 3119
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:5746074"
variation 3217
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="a"
/db_xref="dbSNP:370853008"
variation 3235
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:5746075"
variation 3392
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="c"
/db_xref="dbSNP:191275160"
variation 3546
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace="a"
/replace="g"
/db_xref="dbSNP:183757270"
variation 3589..3590
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/replace=""
/replace="tg"
/db_xref="dbSNP:137939745"
polyA_signal 3657..3662
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
polyA_site 3675
/gene="TNFRSF1B"
/gene_synonym="CD120b; p75; p75TNFR; TBPII; TNF-R-II;
TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80"
/experiment="experimental evidence, no additional details
recorded"
ORIGIN
gcgagcgcagcggagcctggagagaaggcgctgggctgcgagggcgcgagggcgcgagggcagggggcaaccggaccccgcccgcacccatggcgcccgtcgccgtctgggccgcgctggccgtcggactggagctctgggctgcggcgcacgccttgcccgcccaggtggcatttacaccctacgccccggagcccgggagcacatgccggctcagagaatactatgaccagacagctcagatgtgctgcagcaaatgctcgccgggccaacatgcaaaagtcttctgtaccaagacctcggacaccgtgtgtgactcctgtgaggacagcacatacacccagctctggaactgggttcccgagtgcttgagctgtggctcccgctgtagctctgaccaggtggaaactcaagcctgcactcgggaacagaaccgcatctgcacctgcaggcccggctggtactgcgcgctgagcaagcaggaggggtgccggctgtgcgcgccgctgcgcaagtgccgcccgggcttcggcgtggccagaccaggaactgaaacatcagacgtggtgtgcaagccctgtgccccggggacgttctccaacacgacttcatccacggatatttgcaggccccaccagatctgtaacgtggtggccatccctgggaatgcaagcatggatgcagtctgcacgtccacgtcccccacccggagtatggccccaggggcagtacacttaccccagccagtgtccacacgatcccaacacacgcagccaactccagaacccagcactgctccaagcacctccttcctgctcccaatgggccccagccccccagctgaagggagcactggcgacttcgctcttccagttggactgattgtgggtgtgacagccttgggtctactaataataggagtggtgaactgtgtcatcatgacccaggtgaaaaagaagcccttgtgcctgcagagagaagccaaggtgcctcacttgcctgccgataaggcccggggtacacagggccccgagcagcagcacctgctgatcacagcgccgagctccagcagcagctccctggagagctcggccagtgcgttggacagaagggcgcccactcggaaccagccacaggcaccaggcgtggaggccagtggggccggggaggcccgggccagcaccgggagctcagattcttcccctggtggccatgggacccaggtcaatgtcacctgcatcgtgaacgtctgtagcagctctgaccacagctcacagtgctcctcccaagccagctccacaatgggagacacagattccagcccctcggagtccccgaaggacgagcaggtccccttctccaaggaggaatgtgcctttcggtcacagctggagacgccagagaccctgctggggagcaccgaagagaagcccctgccccttggagtgcctgatgctgggatgaagcccagttaaccaggccggtgtgggctgtgtcgtagccaaggtgggctgagccctggcaggatgaccctgcgaaggggccctggtccttccaggcccccaccactaggactctgaggctctttctgggccaagttcctctagtgccctccacagccgcagcctccctctgacctgcaggccaagagcagaggcagcgagttgtggaaagcctctgctgccatggcgtgtccctctcggaaggctggctgggcatggacgttcggggcatgctggggcaagtccctgactctctgtgacctgccccgcccagctgcacctgccagcctggcttctggagcccttgggttttttgtttgtttgtttgtttgtttgtttgtttctccccctgggctctgccccagctctggcttccagaaaaccccagcatccttttctgcagaggggctttctggagaggagggatgctgcctgagtcacccatgaagacaggacagtgcttcagcctgaggctgagactgcgggatggtcctggggctctgtgcagggaggaggtggcagccctgtagggaacggggtccttcaagttagctcaggaggcttggaaagcatcacctcaggccaggtgcagtggctcacgcctatgatcccagcactttgggaggctgaggcgggtggatcacctgaggttaggagttcgagaccagcctggccaacatggtaaaaccccatctctactaaaaatacagaaattagccgggcgtggtggcgggcacctatagtcccagctactcagaagcctgaggctgggaaatcgtttgaacccgggaagcggaggttgcagggagccgagatcacgccactgcactccagcctgggcgacagagcgagagtctgtctcaaaagaaaaaaaaaagcaccgcctccaaatgccaacttgtccttttgtaccatggtgtgaaagtcagatgcccagagggcccaggcaggccaccatattcagtgctgtggcctgggcaagataacgcacttctaactagaaatctgccaattttttaaaaaagtaagtaccactcaggccaacaagccaacgacaaagccaaactctgccagccacatccaaccccccacctgccatttgcaccctccgccttcactccggtgtgcctgcagccccgcgcctccttccttgctgtcctaggccacaccatctcctttcagggaatttcaggaactagagatgactgagtcctcgtagccatctctctactcctacctcagcctagaccctcctcctcccccagaggggtgggttcctcttccccactccccaccttcaattcctgggccccaaacgggctgccctgccactttggtacatggccagtgtgatcccaagtgccagtcttgtgtctgcgtctgtgttgcgtgtcgtgggtgtgtgtagccaaggtcggtaagttgaatggcctgccttgaagccactgaagctgggattcctccccattagagtcagccttccccctcccagggccagggccctgcagaggggaaaccagtgtagccttgcccggattctgggaggaagcaggttgaggggctcctggaaaggctcagtctcaggagcatggggataaaggagaaggcatgaaattgtctagcagagcaggggcagggtgataaattgttgataaattccactggacttgagcttggcagctgaactattggagggtgggagagcccagccattaccatggagacaagaagggttttccaccctggaatcaagatgtcagactggctggctgcagtgacgtgcacctgtactcaggaggctgaggggaggatcactggagcccaggagtttgaggctgcagcgagctatgatcgcgccactacactccagcctgagcaacagagtgagaccctgtctcttaaagaaaaaaaaagtcagactgctgggactggccaggtttctgcccacattggacccacatgaggacatgatggagcgcacctgccccctggtggacagtcctgggagaacctcaggcttccttggcatcacagggcagagccgggaagcgatgaatttggagactctgtggggccttggttcccttgtgtgtgtgtgttgatcccaagacaatgaaagtttgcactgtatgctggacggcattcctgcttatcaataaacctgtttgttttaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:7133 -> Molecular function: GO:0005031 [tumor necrosis factor-activated receptor activity] evidence: IEA
GeneID:7133 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:7133 -> Molecular function: GO:0031625 [ubiquitin protein ligase binding] evidence: IPI
GeneID:7133 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:7133 -> Biological process: GO:0006954 [inflammatory response] evidence: IEA
GeneID:7133 -> Biological process: GO:0006955 [immune response] evidence: IEA
GeneID:7133 -> Biological process: GO:0050728 [negative regulation of inflammatory response] evidence: IEA
GeneID:7133 -> Biological process: GO:0050779 [RNA destabilization] evidence: IEA
GeneID:7133 -> Biological process: GO:0051044 [positive regulation of membrane protein ectodomain proteolysis] evidence: IMP
GeneID:7133 -> Biological process: GO:0071222 [cellular response to lipopolysaccharide] evidence: IMP
GeneID:7133 -> Biological process: GO:0071363 [cellular response to growth factor stimulus] evidence: IEA
GeneID:7133 -> Cellular component: GO:0005576 [extracellular region] evidence: IEA
GeneID:7133 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
GeneID:7133 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA
GeneID:7133 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:7133 -> Cellular component: GO:0043025 [neuronal cell body] evidence: IEA
GeneID:7133 -> Cellular component: GO:0043196 [varicosity] evidence: IEA
GeneID:7133 -> Cellular component: GO:0045121 [membrane raft] evidence: IDA
GeneID:7133 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
by
@meso_cacase at
DBCLS
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