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2024-04-24 23:28:41, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001042751 6075 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens stromal antigen 2 (STAG2), transcript variant 3, mRNA.
ACCESSION NM_001042751
VERSION NM_001042751.1 GI:112789529
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6075)
AUTHORS Chung,N.G., Kim,M.S., Yoo,N.J. and Lee,S.H.
TITLE Somatic mutation of STAG2, an aneuploidy-related gene, is rare in
acute leukemias
JOURNAL Leuk. Lymphoma 53 (6), 1234-1235 (2012)
PUBMED 22132872
REMARK GeneRIF: Somatic mutation of STAG2, an aneuploidy-related gene, is
rare in acute leukemias.
REFERENCE 2 (bases 1 to 6075)
AUTHORS Kim,M.S., Kim,S.S., Je,E.M., Yoo,N.J. and Lee,S.H.
TITLE Mutational and expressional analyses of STAG2 gene in solid cancers
JOURNAL Neoplasma 59 (5), 524-529 (2012)
PUBMED 22668012
REMARK GeneRIF: Low STAG2 expression and not mutation is associated with
neoplasms.
REFERENCE 3 (bases 1 to 6075)
AUTHORS Solomon,D.A., Kim,T., Diaz-Martinez,L.A., Fair,J., Elkahloun,A.G.,
Harris,B.T., Toretsky,J.A., Rosenberg,S.A., Shukla,N., Ladanyi,M.,
Samuels,Y., James,C.D., Yu,H., Kim,J.S. and Waldman,T.
TITLE Mutational inactivation of STAG2 causes aneuploidy in human cancer
JOURNAL Science 333 (6045), 1039-1043 (2011)
PUBMED 21852505
REMARK GeneRIF: study has shown that diverse human cancers harbor
mutations in the X-linked chromatid cohesion gene STAG2 and that
these mutations cause aneuploidy
REFERENCE 4 (bases 1 to 6075)
AUTHORS Xiao,T., Wallace,J. and Felsenfeld,G.
TITLE Specific sites in the C terminus of CTCF interact with the SA2
subunit of the cohesin complex and are required for
cohesin-dependent insulation activity
JOURNAL Mol. Cell. Biol. 31 (11), 2174-2183 (2011)
PUBMED 21444719
REMARK GeneRIF: results demonstrate specific sites on C terminus of CTCF
are essential for cohesin binding and insulator function; only
direct interaction between CTCF and cohesin involves contact with
SA2, which is external to the cohesin ring
REFERENCE 5 (bases 1 to 6075)
AUTHORS Canudas,S. and Smith,S.
TITLE Differential regulation of telomere and centromere cohesion by the
Scc3 homologues SA1 and SA2, respectively, in human cells
JOURNAL J. Cell Biol. 187 (2), 165-173 (2009)
PUBMED 19822671
REMARK GeneRIF: cohesin(SA1) and cohesin(SA2) are differentially required
for telomere and centromere cohesion, respectively.
REFERENCE 6 (bases 1 to 6075)
AUTHORS Prieto,I., Pezzi,N., Buesa,J.M., Kremer,L., Barthelemy,I.,
Carreiro,C., Roncal,F., Martinez,A., Gomez,L., Fernandez,R.,
Martinez-A,C. and Barbero,J.L.
TITLE STAG2 and Rad21 mammalian mitotic cohesins are implicated in
meiosis
JOURNAL EMBO Rep. 3 (6), 543-550 (2002)
PUBMED 12034751
REFERENCE 7 (bases 1 to 6075)
AUTHORS Gregson,H.C., Schmiesing,J.A., Kim,J.S., Kobayashi,T., Zhou,S. and
Yokomori,K.
TITLE A potential role for human cohesin in mitotic spindle aster
assembly
JOURNAL J. Biol. Chem. 276 (50), 47575-47582 (2001)
PUBMED 11590136
REFERENCE 8 (bases 1 to 6075)
AUTHORS Sumara,I., Vorlaufer,E., Gieffers,C., Peters,B.H. and Peters,J.M.
TITLE Characterization of vertebrate cohesin complexes and their
regulation in prophase
JOURNAL J. Cell Biol. 151 (4), 749-762 (2000)
PUBMED 11076961
REFERENCE 9 (bases 1 to 6075)
AUTHORS Carramolino,L., Lee,B.C., Zaballos,A., Peled,A., Barthelemy,I.,
Shav-Tal,Y., Prieto,I., Carmi,P., Gothelf,Y., Gonzalez de
Buitrago,G., Aracil,M., Marquez,G., Barbero,J.L. and Zipori,D.
TITLE SA-1, a nuclear protein encoded by one member of a novel gene
family: molecular cloning and detection in hemopoietic organs
JOURNAL Gene 195 (2), 151-159 (1997)
PUBMED 9305759
REMARK Erratum:[Gene 1998 Jan 12;206(2):283]
REFERENCE 10 (bases 1 to 6075)
AUTHORS Wu,C., Friedlander,P., Lamoureux,C., Zannis-Hadjopoulos,M. and
Price,G.B.
TITLE cDNA clones contain autonomous replication activity
JOURNAL Biochim. Biophys. Acta 1174 (3), 241-257 (1993)
PUBMED 7690594
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DA214149.1, BX641003.1, BC001765.1, CB250478.1, BC017095.1 and
AA428995.1.
Transcript Variant: This variant (3) differs in the 5' UTR and
lacks an alternate in-frame exon, compared to variant 1, resulting
in a shorter protein (isoform b), compared to isoform a. Variants 3
and 4 encode the same isoform.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BX641003.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025088, ERS025091 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-33 DA214149.1 1-33
34-1687 BX641003.1 3-1656
1688-4310 BC001765.1 1572-4194
4311-4927 CB250478.1 34-650
4928-5911 BC017095.1 139-1122
5912-6075 AA428995.1 1-164 c
FEATURES Location/Qualifiers
source 1..6075
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq25"
gene 1..6075
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/note="stromal antigen 2"
/db_xref="GeneID:10735"
/db_xref="HGNC:11355"
/db_xref="MIM:300826"
exon 1..151
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 152..216
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 161
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:181281376"
variation 195
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:370410456"
exon 217..357
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
misc_feature 287..289
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/note="upstream in-frame stop codon"
CDS 314..4009
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/note="isoform b is encoded by transcript variant 3; SCC3
homolog 2; cohesin subunit SA-2"
/codon_start=1
/product="cohesin subunit SA-2 isoform b"
/protein_id="NP_001036216.1"
/db_xref="GI:112789530"
/db_xref="CCDS:CCDS14607.1"
/db_xref="GeneID:10735"
/db_xref="HGNC:11355"
/db_xref="MIM:300826"
/translation="
MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGGGKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGIENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF
"
misc_feature 314..316
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="N-acetylmethionine; propagated from
UniProtKB/Swiss-Prot (Q8N3U4.3); acetylation site"
misc_feature 773..1093
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/note="STAG domain; Region: STAG; pfam08514"
/db_xref="CDD:117091"
misc_feature 2132..2134
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q8N3U4.3); acetylation site"
misc_feature 3485..3487
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8N3U4.3); phosphorylation site"
misc_feature 3494..3496
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8N3U4.3); phosphorylation site"
misc_feature 3494..3496
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3503..3505
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3506..3508
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3647..3649
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8N3U4.3); phosphorylation site"
misc_feature 3842..3844
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8N3U4.3); phosphorylation site"
misc_feature 3845..3847
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8N3U4.3); phosphorylation site"
variation 352
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:368486031"
exon 358..436
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 371
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:188035163"
variation 379
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:201477761"
variation 409
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:367889026"
exon 437..601
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 602..698
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 648
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140238058"
variation 673
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199921026"
exon 699..775
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 710
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:150057715"
variation 721
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:145475901"
exon 776..980
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 854
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:202127296"
variation 907
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:12838265"
exon 981..1132
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1087
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201520178"
variation 1095
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:148395642"
exon 1133..1206
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 1207..1330
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 1331..1429
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
STS 1352..1484
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52332"
/db_xref="UniSTS:377132"
variation 1357
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:193169542"
variation 1366
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201201019"
variation 1402
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:185398645"
variation 1414
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:190643141"
exon 1430..1509
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1507
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:372829731"
exon 1510..1617
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1531
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200552026"
variation 1561
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:142571900"
exon 1618..1729
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1655
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:146439650"
variation 1672
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370465019"
exon 1730..1847
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1762
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140900528"
variation 1823
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="g"
/replace="t"
/db_xref="dbSNP:180841941"
exon 1848..1951
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1864
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201565008"
variation 1883
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:144820719"
variation 1902
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:5911741"
variation 1942
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:202037021"
exon 1952..2044
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 2045..2134
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2047
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:146721074"
exon 2135..2338
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2313
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:369728409"
variation 2318
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="c"
/db_xref="dbSNP:140406522"
variation 2330
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:184717615"
exon 2339..2409
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2356
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:371293594"
variation 2395
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:10217943"
exon 2410..2497
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2410
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="g"
/replace="t"
/db_xref="dbSNP:6655782"
variation 2419
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:373076947"
variation 2451
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:112417641"
variation 2489
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:138155911"
exon 2498..2578
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 2579..2671
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 2672..2846
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2694
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:149551481"
exon 2847..2986
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2911
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:201474861"
variation 2914
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:374308808"
variation 2971
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:368522338"
exon 2987..3088
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2998
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200047549"
exon 3089..3237
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3142
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:202140215"
exon 3238..3366
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3337
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:368960276"
exon 3367..3590
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3404
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:370347095"
variation 3491
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:146561651"
variation 3519
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:11555621"
variation 3544
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:139192022"
variation 3545
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:373076855"
exon 3591..3780
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3673
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:34567090"
variation 3678
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:370975120"
variation 3700
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:374627302"
variation 3714
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:5911751"
variation 3743
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:147520054"
exon 3781..3907
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3871
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:372132155"
variation 3893
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:182467825"
exon 3908..3985
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3982
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:201262699"
exon 3986..6068
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 4048
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:377029295"
STS 4052..4287
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52548"
/db_xref="UniSTS:377348"
variation 4059
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:369223493"
variation 4096
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:111649101"
variation 4097
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:186381656"
STS 4151..5308
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="stSG633685"
/db_xref="UniSTS:460325"
variation 4256..4259
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="gtta"
/db_xref="dbSNP:368531652"
STS 4264..4524
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52549"
/db_xref="UniSTS:377349"
variation 4296
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="a"
/db_xref="dbSNP:67492414"
variation 4304
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="c"
/db_xref="dbSNP:113412506"
STS 4319..4874
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="ECD12003"
/db_xref="UniSTS:293036"
STS 4501..4728
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52550"
/db_xref="UniSTS:377350"
variation 4583
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:144559029"
STS 4670..4933
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52551"
/db_xref="UniSTS:377351"
STS 4918..5170
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52552"
/db_xref="UniSTS:377352"
variation 4933
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="g"
/replace="t"
/db_xref="dbSNP:183029659"
variation 4952
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:1044020"
STS 5095..5680
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="ECD10983"
/db_xref="UniSTS:292020"
STS 5130..5391
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52553"
/db_xref="UniSTS:377353"
variation 5149
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:187706335"
variation 5362..5365
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="ctat"
/db_xref="dbSNP:72013495"
STS 5368..5607
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52554"
/db_xref="UniSTS:377354"
variation 5527
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:192624442"
STS 5583..5835
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52555"
/db_xref="UniSTS:377355"
STS 5662..5892
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="DXS8321"
/db_xref="UniSTS:77560"
variation 5790..5791
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="aa"
/db_xref="dbSNP:71761944"
polyA_signal 5891..5896
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
polyA_signal 5897..5902
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
polyA_site 5909
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
variation 5932
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:377387979"
variation 5941
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370425648"
variation 5962
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:183365442"
polyA_signal 6042..6047
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
polyA_site 6068
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
ORIGIN
ctctcttcctcccttcctagagagggaacaacattcatgtgacgggcccctctgcttctcccccgccccatcatctccagcgcgtggtgggggaactgctggggaaggcgattggcatcgatctctccatcccttccgaggcccgacttcggtggccaccgagtactaaattcacttgggaataaaagaaaaacataagaaaattataagagaaaggaattgtcttagaagaaagaaggcaagccaccattttacccacgtaaatatatgaatatatttctgacattgaggtgttccagaagatgataaagaaatgatagcagctccagaaataccaactgattttaatctactacaggagtcagaaacacatttttcttctgacacagattttgaagatatcgaaggaaaaaaccaaaagcaaggcaaaggcaaaacttgtaaaaaaggcaaaaagggcccagcagaaaagggcaaaggtggaaatggaggaggaaaacctccttctggtccaaaccgaatgaatggtcatcaccaacagaatggagtggaaaacatgatgttgtttgaagttgttaaaatgggcaagagtgctatgcagtcggtggtagatgattggatagaatcatacaagcatgaccgagatatagcacttcttgaccttatcaacttttttattcagtgttcaggctgtaaaggagttgtcacagcagaaatgtttagacatatgcagaactctgagataattcgaaaaatgactgaagaattcgatgaggatagtggagattatccacttaccatggctggtcctcagtggaagaagttcaaatccagtttttgtgaattcattggcgtgttagtacggcaatgtcaatatagtatcatatatgatgagtatatgatggatacagtcatttcacttcttacaggattgtctgactcacaagtcagagcatttcgacatacaagcaccctggcagctatgaagttgatgacagctttggtgaatgtggcactaaatcttagcattaatatggataatacacaaagacaatatgaagcagaacggaataaaatgattggaaaacgagccaatgagaggctagaactcctgctacaaaagcggaaagagcttcaggaaaatcaagatgaaatagaaaatatgatgaatgcaatatttaaaggagtgtttgtacatagataccgtgatgcgatagctgaaattcgagctatttgcattgaagagattggcatttggatgaagatgtatagtgatgcctttcttaatgacagttatttaaaatatgttggttggactatgcatgataagcaaggtgaagtaagactcaaatgtcttactgctctacaagggctttattataacaaagagcttaattccaaactggaactttttaccagtcggttcaaggatagaattgtgtctatgacccttgacaaagaatatgatgttgcagtacaagcaataaaattactcactcttgttttacagagtagtgaagaagttctcactgcagaagattgtgaaaatgtctatcatctggtttattcagctcaccggccagtagcagtagcagctggagaatttctctacaaaaagctcttcagtcgtagagatccagaggaggatggaatgatgaaaagaagaggaagacaaggtccaaatgccaaccttgttaagacattggtttttttctttctagaaagtgagttacatgagcatgcagcataccttgtggatagcatgtgggactgtgctactgagctgctgaaagactgggaatgtatgaatagcttgttactggaagagccacttagtggagaggaagcactaacagataggcaagagagtgctctgattgaaataatgctttgtaccattagacaagcggctgaatgtcatcctcccgtgggaagagggacaggaaaaagggtgcttacagcaaaggagaagaagacacagttggatgataggacaaaaatcactgagctttttgccgtggcccttcctcagttattagcaaaatactctgtagatgcagaaaaggtgactaacttgttgcagttgcctcagtactttgatttggaaatatataccactggacgattagaaaagcatttggatgccttattgcgacagatccggaatattgtagagaagcacacagatacagatgttttggaagcatgttctaaaacttaccatgcactctgtaatgaagagttcacaatcttcaacagagtagatatttcaagaagtcaactgatagatgaattggcagataaatttaaccggcttcttgaagattttctgcaagagggtgaagaacctgatgaagatgatgcatatcaggtattgtcaacattgaagaggatcactgcttttcataatgcccatgacctttcaaagtgggatttatttgcttgtaattacaaactcttgaaaactggaatcgaaaatggagacatgcctgagcagattgttattcacgcactgcagtgtactcactatgtaatcctttggcaacttgctaagataactgaaagcagctctacaaaggaggacttgctgcgtttaaagaaacaaatgagagtattttgtcagatatgtcaacattacctgaccaacgtgaatactactgttaaggaacaggccttcactattctgtgtgatattttgatgatcttcagccatcagattatgtcaggagggcgtgacatgttagagccattagtgtatacccctgattcttcattgcagtctgagttgctcagctttattttggatcatgtcttcattgaacaggatgatgataataatagtgcagatggtcagcaagaggatgaagccagtaaaattgaagctctgcacaagagaagaaatttacttgcagcattttgtaagctaattgtatatactgtggtggagatgaatacagctgcagatatcttcaaacagtatatgaagtattataatgactatggagatatcatcaaagaaacaatgagtaaaacaaggcagatagacaaaattcagtgtgctaagacccttattctcagtctgcaacagctttttaatgaaatgatacaagaaaatggctataattttgatagatcatcctctacatttagtggcataaaagaacttgctcgacgttttgctttaacttttggacttgatcagttgaaaacaagagaagccattgccatgctacacaaagatggcatagaatttgcttttaaagagcctaatccgcaaggggagagccatccacctttaaatttggcatttcttgatattctgagtgaattttcttctaaactacttcgacaagacaaaagaacagtgtatgtttacttggaaaagttcatgacctttcagatgtcactccgaagagaggatgtgtggcttccactgatgtcttaccgaaattctttgctagctggtggtgatgatgacaccatgtcagtcattagtggaatcagcagccgggggtcaacagtacggagtaaaaaatcaaaaccatctacaggaaaacggaaagtggttgagggcatgcagctttcactcactgaagaaagtagtagtagtgacagtatgtggttaagcagagaacaaacactgcacacccctgttatgatgcagacaccacaactcacctccactattatgagagagcccaaaagattacggcctgaggatagcttcatgagtgtttatccaatgcagactgaacatcatcaaacacctcttgattataatcggcgtggcacaagcctaatggaagatgatgaagagccaattgtggaagatgttatgatgtcctcagaagggaggattgaggatcttaatgagggaatggattttgacaccatggatatagatttgccaccatcaaagaacagacgagagagaacagaactgaagcctgatttctttgatccagcttcaattatggatgaatcagttcttggagtgtcaatgttttaataccagtacacaattaaatctgtggtgaagtcattttctaagtggaagaggaaattttaaagtgtggtagatacagtgaaattctgtacagatttttctctaaggagaatatgacatgcttatgcttaccaagatcaagtgcattgaggggcagttttgtttgcctgaataaacgtaaaggacaagtaaacaatttgatgataagctacagtttttcttagaaagtaaatattttatttatgcgctgttagttggcttttgaatcgattatttcatgcttttttttaaaaaaaaaaaaaaacaaaataacaatctgaagaggcatttggtacagatatgaattctcttacatttatttactggttgtactaaataatgatgacctctgctggatttctgtttacatccagaaaacaatgttaaggatgtatttattcccctaccctgaagaaagtgtaggatagaattgtttttagcattctaaatttaaatgcttaaaacgtcaatcaacaaaactttgttttaaatattgtaattgtggagaaaagtaaacttataagcagaacttttacaattttttcatctaaaagtattttaagatatttttaaaatccaagagcttctctatacttttcagaaatatccagatgcagtgaactgccagaaggtaaccagtctcaaacatgcttatcccattatcaaccctgaaagtttgcttgtcctttaagataaaaatgtaatgttgtgatattccttccagtaatgccactgtattttgtctccaaataaaagaagcttattgtagtatgtttgcagaaaaattctaaacaaaaattatacagcttattagagtgtgggaatagggatctaaattttaaataaaattatatatatatataaattggtgctgattttataattgcgcagtttgtttagttttttcttacttttaaattccaacttaaaattatgaggtttcagaaatatattgaaagtttaacaatgtttaaaaatagaaaagcatgagtgttcatgctttaaaatgatttttaaatttgtattttatattgttttatctatctgtctttgcaagcagtcttcaggttaaagatacttctaacaggttacagtacatttcctctgtatgtaaattagatgggataatagaattcataacccataatattctttgaaagctaagctttaaacttcattttatgtcctttcacaaataaattagtttaaaacagaaagtggctacttgccattttgacatcaactcattttgcgaggcttaggcagctagacatcgtttaaaacaaaatattaacttatattacatgtgtatctatctattgtcagtcgtctctcagttcttgaggtatattattttaatcattccatgccttaatatgcttgcaatacaagaatatcttcagatgggtgaataccaaaaggctttcagtttttagtcagaaatcaagcattgggctgtggtagccaaaaaccataggttagctaaaaagatcatgatacaattattttattaagtcatggttaataacaaatgaatccagacttgtctaacagattttccatcaacaaatattgttatgtgcaaaagtattgcctatgttgttttacacaccactgcattaactagaactgctgagaggactgtatatatgattttaaacctaagttgattttttttctcactcttgaaaggagtacttctttgtgaaagcagttcttacagctttgttttcaaccagctaaaaatgttttatatattactctaacctgttgtcctccacattctattgtcctaattgtactgttttctgatttgtatttatgtcttgagacagtaactttttgaataaaaataaacctacagtatgttgtatgttttctcttgtactcaaagggggagggtggctataaatggtttgcaaatttatatctattatcacatcttttaatgtgtttggggaataatttatagagaataccatcagtttatatttttaataaatcatatgtatttacaatgaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:10735 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:10735 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
GeneID:10735 -> Biological process: GO:0000910 [cytokinesis] evidence: TAS
GeneID:10735 -> Biological process: GO:0007062 [sister chromatid cohesion] evidence: IMP
GeneID:10735 -> Biological process: GO:0007067 [mitosis] evidence: IEA
GeneID:10735 -> Biological process: GO:0007126 [meiosis] evidence: IEA
GeneID:10735 -> Biological process: GO:0019827 [stem cell maintenance] evidence: IEA
GeneID:10735 -> Biological process: GO:0032876 [negative regulation of DNA endoreduplication] evidence: IMP
GeneID:10735 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: TAS
GeneID:10735 -> Cellular component: GO:0000785 [chromatin] evidence: IDA
GeneID:10735 -> Cellular component: GO:0005634 [nucleus] evidence: TAS
GeneID:10735 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:10735 -> Cellular component: GO:0005694 [chromosome] evidence: TAS
GeneID:10735 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
by
@meso_cacase at
DBCLS
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