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2024-04-20 08:22:07, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001042749 6277 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens stromal antigen 2 (STAG2), transcript variant 1, mRNA.
ACCESSION NM_001042749
VERSION NM_001042749.1 GI:112789525
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6277)
AUTHORS Chung,N.G., Kim,M.S., Yoo,N.J. and Lee,S.H.
TITLE Somatic mutation of STAG2, an aneuploidy-related gene, is rare in
acute leukemias
JOURNAL Leuk. Lymphoma 53 (6), 1234-1235 (2012)
PUBMED 22132872
REMARK GeneRIF: Somatic mutation of STAG2, an aneuploidy-related gene, is
rare in acute leukemias.
REFERENCE 2 (bases 1 to 6277)
AUTHORS Kim,M.S., Kim,S.S., Je,E.M., Yoo,N.J. and Lee,S.H.
TITLE Mutational and expressional analyses of STAG2 gene in solid cancers
JOURNAL Neoplasma 59 (5), 524-529 (2012)
PUBMED 22668012
REMARK GeneRIF: Low STAG2 expression and not mutation is associated with
neoplasms.
REFERENCE 3 (bases 1 to 6277)
AUTHORS Solomon,D.A., Kim,T., Diaz-Martinez,L.A., Fair,J., Elkahloun,A.G.,
Harris,B.T., Toretsky,J.A., Rosenberg,S.A., Shukla,N., Ladanyi,M.,
Samuels,Y., James,C.D., Yu,H., Kim,J.S. and Waldman,T.
TITLE Mutational inactivation of STAG2 causes aneuploidy in human cancer
JOURNAL Science 333 (6045), 1039-1043 (2011)
PUBMED 21852505
REMARK GeneRIF: study has shown that diverse human cancers harbor
mutations in the X-linked chromatid cohesion gene STAG2 and that
these mutations cause aneuploidy
REFERENCE 4 (bases 1 to 6277)
AUTHORS Xiao,T., Wallace,J. and Felsenfeld,G.
TITLE Specific sites in the C terminus of CTCF interact with the SA2
subunit of the cohesin complex and are required for
cohesin-dependent insulation activity
JOURNAL Mol. Cell. Biol. 31 (11), 2174-2183 (2011)
PUBMED 21444719
REMARK GeneRIF: results demonstrate specific sites on C terminus of CTCF
are essential for cohesin binding and insulator function; only
direct interaction between CTCF and cohesin involves contact with
SA2, which is external to the cohesin ring
REFERENCE 5 (bases 1 to 6277)
AUTHORS Canudas,S. and Smith,S.
TITLE Differential regulation of telomere and centromere cohesion by the
Scc3 homologues SA1 and SA2, respectively, in human cells
JOURNAL J. Cell Biol. 187 (2), 165-173 (2009)
PUBMED 19822671
REMARK GeneRIF: cohesin(SA1) and cohesin(SA2) are differentially required
for telomere and centromere cohesion, respectively.
REFERENCE 6 (bases 1 to 6277)
AUTHORS Prieto,I., Pezzi,N., Buesa,J.M., Kremer,L., Barthelemy,I.,
Carreiro,C., Roncal,F., Martinez,A., Gomez,L., Fernandez,R.,
Martinez-A,C. and Barbero,J.L.
TITLE STAG2 and Rad21 mammalian mitotic cohesins are implicated in
meiosis
JOURNAL EMBO Rep. 3 (6), 543-550 (2002)
PUBMED 12034751
REFERENCE 7 (bases 1 to 6277)
AUTHORS Gregson,H.C., Schmiesing,J.A., Kim,J.S., Kobayashi,T., Zhou,S. and
Yokomori,K.
TITLE A potential role for human cohesin in mitotic spindle aster
assembly
JOURNAL J. Biol. Chem. 276 (50), 47575-47582 (2001)
PUBMED 11590136
REFERENCE 8 (bases 1 to 6277)
AUTHORS Sumara,I., Vorlaufer,E., Gieffers,C., Peters,B.H. and Peters,J.M.
TITLE Characterization of vertebrate cohesin complexes and their
regulation in prophase
JOURNAL J. Cell Biol. 151 (4), 749-762 (2000)
PUBMED 11076961
REFERENCE 9 (bases 1 to 6277)
AUTHORS Carramolino,L., Lee,B.C., Zaballos,A., Peled,A., Barthelemy,I.,
Shav-Tal,Y., Prieto,I., Carmi,P., Gothelf,Y., Gonzalez de
Buitrago,G., Aracil,M., Marquez,G., Barbero,J.L. and Zipori,D.
TITLE SA-1, a nuclear protein encoded by one member of a novel gene
family: molecular cloning and detection in hemopoietic organs
JOURNAL Gene 195 (2), 151-159 (1997)
PUBMED 9305759
REMARK Erratum:[Gene 1998 Jan 12;206(2):283]
REFERENCE 10 (bases 1 to 6277)
AUTHORS Wu,C., Friedlander,P., Lamoureux,C., Zannis-Hadjopoulos,M. and
Price,G.B.
TITLE cDNA clones contain autonomous replication activity
JOURNAL Biochim. Biophys. Acta 1174 (3), 241-257 (1993)
PUBMED 7690594
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DA534452.1, BX640970.1, BC001765.1, BC017095.1 and AA428995.1.
Transcript Variant: This variant (1) represents the longest
transcript and encodes the longer isoform (a). Variants 1 and 2
encode the same isoform.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BX640970.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-80 DA534452.1 1-80
81-852 BX640970.1 1-772
853-3871 BC001765.1 646-3664
3872-4511 BX640970.1 3792-4431
4512-4512 BC001765.1 4194-4194
4513-5112 BX640970.1 4432-5031
5113-6113 BC017095.1 122-1122
6114-6277 AA428995.1 1-164 c
FEATURES Location/Qualifiers
source 1..6277
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq25"
gene 1..6277
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/note="stromal antigen 2"
/db_xref="GeneID:10735"
/db_xref="HGNC:11355"
/db_xref="MIM:300826"
exon 1..242
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 183
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:190699960"
exon 243..307
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 252
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:181281376"
variation 286
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:370410456"
exon 308..448
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
misc_feature 378..380
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/note="upstream in-frame stop codon"
CDS 405..4211
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/note="isoform a is encoded by transcript variant 1; SCC3
homolog 2; cohesin subunit SA-2"
/codon_start=1
/product="cohesin subunit SA-2 isoform a"
/protein_id="NP_001036214.1"
/db_xref="GI:112789526"
/db_xref="CCDS:CCDS43990.1"
/db_xref="GeneID:10735"
/db_xref="HGNC:11355"
/db_xref="MIM:300826"
/translation="
MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGGGKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGIENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHHQTPLDYNTQVTWMLAQRQQEEARQQQERAAMSYVKLRTNLQHAIRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF
"
misc_feature 864..1184
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/note="STAG domain; Region: STAG; pfam08514"
/db_xref="CDD:117091"
misc_feature 3585..3587
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3594..3596
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3597..3599
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
variation 443
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:368486031"
exon 449..527
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 462
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:188035163"
variation 470
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:201477761"
variation 500
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:367889026"
exon 528..692
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 693..789
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 739
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140238058"
variation 764
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199921026"
exon 790..866
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 801
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:150057715"
variation 812
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:145475901"
exon 867..1071
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 945
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:202127296"
variation 998
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:12838265"
exon 1072..1223
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1178
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201520178"
variation 1186
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:148395642"
exon 1224..1297
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 1298..1421
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 1422..1520
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
STS 1443..1575
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52332"
/db_xref="UniSTS:377132"
variation 1448
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:193169542"
variation 1457
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201201019"
variation 1493
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:185398645"
variation 1505
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:190643141"
exon 1521..1600
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1598
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:372829731"
exon 1601..1708
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1622
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200552026"
variation 1652
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:142571900"
exon 1709..1820
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1746
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:146439650"
variation 1763
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370465019"
exon 1821..1938
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1853
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140900528"
variation 1914
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="g"
/replace="t"
/db_xref="dbSNP:180841941"
exon 1939..2042
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 1955
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201565008"
variation 1974
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:144820719"
variation 1993
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:5911741"
variation 2033
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:202037021"
exon 2043..2135
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 2136..2225
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2138
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:146721074"
exon 2226..2429
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2404
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:369728409"
variation 2409
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="c"
/db_xref="dbSNP:140406522"
variation 2421
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:184717615"
exon 2430..2500
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2447
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:371293594"
variation 2486
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:10217943"
exon 2501..2588
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2501
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="g"
/replace="t"
/db_xref="dbSNP:6655782"
variation 2510
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:373076947"
variation 2542
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:112417641"
variation 2580
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:138155911"
exon 2589..2669
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 2670..2762
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
exon 2763..2937
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 2785
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:149551481"
exon 2938..3077
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3002
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:201474861"
variation 3005
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:374308808"
variation 3062
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:368522338"
exon 3078..3179
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3089
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200047549"
exon 3180..3328
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3233
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:202140215"
exon 3329..3457
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3428
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:368960276"
exon 3458..3681
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3495
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:370347095"
variation 3582
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:146561651"
variation 3610
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:11555621"
variation 3635
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:139192022"
variation 3636
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:373076855"
exon 3682..3871
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3764
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:34567090"
variation 3769
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:370975120"
variation 3791
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:374627302"
variation 3805
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:5911751"
variation 3834
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:147520054"
exon 3872..3982
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 3879..3880
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="g"
/db_xref="dbSNP:35494370"
variation 3887
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="g"
/replace="t"
/db_xref="dbSNP:193279915"
variation 3921
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="g"
/db_xref="dbSNP:367702969"
exon 3983..4109
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 4073
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:372132155"
variation 4095
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:182467825"
exon 4110..4187
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 4184
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:201262699"
exon 4188..6270
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/inference="alignment:Splign:1.39.8"
variation 4250
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:377029295"
STS 4254..4489
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52548"
/db_xref="UniSTS:377348"
variation 4261
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:369223493"
variation 4298
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:111649101"
variation 4299
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:186381656"
STS 4353..5510
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="stSG633685"
/db_xref="UniSTS:460325"
variation 4458..4461
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="gtta"
/db_xref="dbSNP:368531652"
STS 4466..4726
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52549"
/db_xref="UniSTS:377349"
variation 4498
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="a"
/db_xref="dbSNP:67492414"
variation 4506
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="c"
/db_xref="dbSNP:113412506"
STS 4521..5076
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="ECD12003"
/db_xref="UniSTS:293036"
STS 4703..4930
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52550"
/db_xref="UniSTS:377350"
variation 4785
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:144559029"
STS 4872..5135
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52551"
/db_xref="UniSTS:377351"
STS 5120..5372
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52552"
/db_xref="UniSTS:377352"
variation 5135
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="g"
/replace="t"
/db_xref="dbSNP:183029659"
variation 5154
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:1044020"
STS 5297..5882
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="ECD10983"
/db_xref="UniSTS:292020"
STS 5332..5593
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52553"
/db_xref="UniSTS:377353"
variation 5351
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="t"
/db_xref="dbSNP:187706335"
variation 5564..5567
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="ctat"
/db_xref="dbSNP:72013495"
STS 5570..5809
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52554"
/db_xref="UniSTS:377354"
variation 5729
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:192624442"
STS 5785..6037
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="REN52555"
/db_xref="UniSTS:377355"
STS 5864..6094
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/standard_name="DXS8321"
/db_xref="UniSTS:77560"
variation 5992..5993
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace=""
/replace="aa"
/db_xref="dbSNP:71761944"
polyA_signal 6093..6098
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
polyA_signal 6099..6104
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
polyA_site 6111
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
variation 6134
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:377387979"
variation 6143
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370425648"
variation 6164
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:183365442"
polyA_signal 6244..6249
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
polyA_site 6270
/gene="STAG2"
/gene_synonym="bA517O1.1; SA-2; SA2; SCC3B"
ORIGIN
aaaaaaaaaaaaaaaaaaagaaaaaaaaccccgccggatccgaccgccactttcaaaaccccccaccgctctagaaccgcgggagcttccgtccctgagtagaattcgagggtgtaaagaagaggaaggggaaaaatatcttgtaccagcccaggggtgaagaagcccccggcctgagaaagaaggaggagtgggggaggcgaacagtctcgttgctgcctctgtgtacgctgaggggggaggtggccaccgagtactaaattcacttgggaataaaagaaaaacataagaaaattataagagaaaggaattgtcttagaagaaagaaggcaagccaccattttacccacgtaaatatatgaatatatttctgacattgaggtgttccagaagatgataaagaaatgatagcagctccagaaataccaactgattttaatctactacaggagtcagaaacacatttttcttctgacacagattttgaagatatcgaaggaaaaaaccaaaagcaaggcaaaggcaaaacttgtaaaaaaggcaaaaagggcccagcagaaaagggcaaaggtggaaatggaggaggaaaacctccttctggtccaaaccgaatgaatggtcatcaccaacagaatggagtggaaaacatgatgttgtttgaagttgttaaaatgggcaagagtgctatgcagtcggtggtagatgattggatagaatcatacaagcatgaccgagatatagcacttcttgaccttatcaacttttttattcagtgttcaggctgtaaaggagttgtcacagcagaaatgtttagacatatgcagaactctgagataattcgaaaaatgactgaagaattcgatgaggatagtggagattatccacttaccatggctggtcctcagtggaagaagttcaaatccagtttttgtgaattcattggcgtgttagtacggcaatgtcaatatagtatcatatatgatgagtatatgatggatacagtcatttcacttcttacaggattgtctgactcacaagtcagagcatttcgacatacaagcaccctggcagctatgaagttgatgacagctttggtgaatgtggcactaaatcttagcattaatatggataatacacaaagacaatatgaagcagaacggaataaaatgattggaaaacgagccaatgagaggctagaactcctgctacaaaagcggaaagagcttcaggaaaatcaagatgaaatagaaaatatgatgaatgcaatatttaaaggagtgtttgtacatagataccgtgatgcgatagctgaaattcgagctatttgcattgaagagattggcatttggatgaagatgtatagtgatgcctttcttaatgacagttatttaaaatatgttggttggactatgcatgataagcaaggtgaagtaagactcaaatgtcttactgctctacaagggctttattataacaaagagcttaattccaaactggaactttttaccagtcggttcaaggatagaattgtgtctatgacccttgacaaagaatatgatgttgcagtacaagcaataaaattactcactcttgttttacagagtagtgaagaagttctcactgcagaagattgtgaaaatgtctatcatctggtttattcagctcaccggccagtagcagtagcagctggagaatttctctacaaaaagctcttcagtcgtagagatccagaggaggatggaatgatgaaaagaagaggaagacaaggtccaaatgccaaccttgttaagacattggtttttttctttctagaaagtgagttacatgagcatgcagcataccttgtggatagcatgtgggactgtgctactgagctgctgaaagactgggaatgtatgaatagcttgttactggaagagccacttagtggagaggaagcactaacagataggcaagagagtgctctgattgaaataatgctttgtaccattagacaagcggctgaatgtcatcctcccgtgggaagagggacaggaaaaagggtgcttacagcaaaggagaagaagacacagttggatgataggacaaaaatcactgagctttttgccgtggcccttcctcagttattagcaaaatactctgtagatgcagaaaaggtgactaacttgttgcagttgcctcagtactttgatttggaaatatataccactggacgattagaaaagcatttggatgccttattgcgacagatccggaatattgtagagaagcacacagatacagatgttttggaagcatgttctaaaacttaccatgcactctgtaatgaagagttcacaatcttcaacagagtagatatttcaagaagtcaactgatagatgaattggcagataaatttaaccggcttcttgaagattttctgcaagagggtgaagaacctgatgaagatgatgcatatcaggtattgtcaacattgaagaggatcactgcttttcataatgcccatgacctttcaaagtgggatttatttgcttgtaattacaaactcttgaaaactggaatcgaaaatggagacatgcctgagcagattgttattcacgcactgcagtgtactcactatgtaatcctttggcaacttgctaagataactgaaagcagctctacaaaggaggacttgctgcgtttaaagaaacaaatgagagtattttgtcagatatgtcaacattacctgaccaacgtgaatactactgttaaggaacaggccttcactattctgtgtgatattttgatgatcttcagccatcagattatgtcaggagggcgtgacatgttagagccattagtgtatacccctgattcttcattgcagtctgagttgctcagctttattttggatcatgtcttcattgaacaggatgatgataataatagtgcagatggtcagcaagaggatgaagccagtaaaattgaagctctgcacaagagaagaaatttacttgcagcattttgtaagctaattgtatatactgtggtggagatgaatacagctgcagatatcttcaaacagtatatgaagtattataatgactatggagatatcatcaaagaaacaatgagtaaaacaaggcagatagacaaaattcagtgtgctaagacccttattctcagtctgcaacagctttttaatgaaatgatacaagaaaatggctataattttgatagatcatcctctacatttagtggcataaaagaacttgctcgacgttttgctttaacttttggacttgatcagttgaaaacaagagaagccattgccatgctacacaaagatggcatagaatttgcttttaaagagcctaatccgcaaggggagagccatccacctttaaatttggcatttcttgatattctgagtgaattttcttctaaactacttcgacaagacaaaagaacagtgtatgtttacttggaaaagttcatgacctttcagatgtcactccgaagagaggatgtgtggcttccactgatgtcttaccgaaattctttgctagctggtggtgatgatgacaccatgtcagtcattagtggaatcagcagccgggggtcaacagtacggagtaaaaaatcaaaaccatctacaggaaaacggaaagtggttgagggcatgcagctttcactcactgaagaaagtagtagtagtgacagtatgtggttaagcagagaacaaacactgcacacccctgttatgatgcagacaccacaactcacctccactattatgagagagcccaaaagattacggcctgaggatagcttcatgagtgtttatccaatgcagactgaacatcatcaaacacctcttgattataacacgcaggtaacatggatgttagctcaaagacaacaagaggaagcaaggcaacagcaggagagagcagcaatgagctatgttaaactgcgaactaatcttcagcatgccattcggcgtggcacaagcctaatggaagatgatgaagagccaattgtggaagatgttatgatgtcctcagaagggaggattgaggatcttaatgagggaatggattttgacaccatggatatagatttgccaccatcaaagaacagacgagagagaacagaactgaagcctgatttctttgatccagcttcaattatggatgaatcagttcttggagtgtcaatgttttaataccagtacacaattaaatctgtggtgaagtcattttctaagtggaagaggaaattttaaagtgtggtagatacagtgaaattctgtacagatttttctctaaggagaatatgacatgcttatgcttaccaagatcaagtgcattgaggggcagttttgtttgcctgaataaacgtaaaggacaagtaaacaatttgatgataagctacagtttttcttagaaagtaaatattttatttatgcgctgttagttggcttttgaatcgattatttcatgcttttttttaaaaaaaaaaaaaaacaaaataacaatctgaagaggcatttggtacagatatgaattctcttacatttatttactggttgtactaaataatgatgacctctgctggatttctgtttacatccagaaaacaatgttaaggatgtatttattcccctaccctgaagaaagtgtaggatagaattgtttttagcattctaaatttaaatgcttaaaacgtcaatcaacaaaactttgttttaaatattgtaattgtggagaaaagtaaacttataagcagaacttttacaattttttcatctaaaagtattttaagatatttttaaaatccaagagcttctctatacttttcagaaatatccagatgcagtgaactgccagaaggtaaccagtctcaaacatgcttatcccattatcaaccctgaaagtttgcttgtcctttaagataaaaatgtaatgttgtgatattccttccagtaatgccactgtattttgtctccaaataaaagaagcttattgtagtatgtttgcagaaaaattctaaacaaaaattatacagcttattagagtgtgggaatagggatctaaattttaaataaaattatatatatatataaattggtgctgattttataattgcgcagtttgtttagttttttcttacttttaaattccaacttaaaattatgaggtttcagaaatatattgaaagtttaacaatgtttaaaaatagaaaagcatgagtgttcatgctttaaaatgatttttaaatttgtattttatattgttttatctatctgtctttgcaagcagtcttcaggttaaagatacttctaacaggttacagtacatttcctctgtatgtaaattagatgggataatagaattcataacccataatattctttgaaagctaagctttaaacttcattttatgtcctttcacaaataaattagtttaaaacagaaagtggctacttgccattttgacatcaactcattttgcgaggcttaggcagctagacatcgtttaaaacaaaatattaacttatattacatgtgtatctatctattgtcagtcgtctctcagttcttgaggtatattattttaatcattccatgccttaatatgcttgcaatacaagaatatcttcagatgggtgaataccaaaaggctttcagtttttagtcagaaatcaagcattgggctgtggtagccaaaaaccataggttagctaaaaagatcatgatacaattattttattaagtcatggttaataacaaatgaatccagacttgtctaacagattttccatcaacaaatattgttatgtgcaaaagtattgcctatgttgttttacacaccactgcattaactagaactgctgagaggactgtatatatgattttaaacctaagttgattttttttctcactcttgaaaggagtacttctttgtgaaagcagttcttacagctttgttttcaaccagctaaaaatgttttatatattactctaacctgttgtcctccacattctattgtcctaattgtactgttttctgatttgtatttatgtcttgagacagtaactttttgaataaaaataaacctacagtatgttgtatgttttctcttgtactcaaagggggagggtggctataaatggtttgcaaatttatatctattatcacatcttttaatgtgtttggggaataatttatagagaataccatcagtttatatttttaataaatcatatgtatttacaatgaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:10735 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:10735 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
GeneID:10735 -> Biological process: GO:0000910 [cytokinesis] evidence: TAS
GeneID:10735 -> Biological process: GO:0007062 [sister chromatid cohesion] evidence: IMP
GeneID:10735 -> Biological process: GO:0007067 [mitosis] evidence: IEA
GeneID:10735 -> Biological process: GO:0007126 [meiosis] evidence: IEA
GeneID:10735 -> Biological process: GO:0019827 [stem cell maintenance] evidence: IEA
GeneID:10735 -> Biological process: GO:0032876 [negative regulation of DNA endoreduplication] evidence: IMP
GeneID:10735 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: TAS
GeneID:10735 -> Cellular component: GO:0000785 [chromatin] evidence: IDA
GeneID:10735 -> Cellular component: GO:0005634 [nucleus] evidence: TAS
GeneID:10735 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:10735 -> Cellular component: GO:0005694 [chromosome] evidence: TAS
GeneID:10735 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
by
@meso_cacase at
DBCLS
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