Home |
Help |
Advanced search
2024-04-19 18:37:08, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001042412 8608 bp mRNA linear PRI 24-JUN-2013
DEFINITION Homo sapiens cylindromatosis (turban tumor syndrome) (CYLD),
transcript variant 3, mRNA.
ACCESSION NM_001042412
VERSION NM_001042412.1 GI:109637775
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8608)
AUTHORS Yang,W.L., Jin,G., Li,C.F., Jeong,Y.S., Moten,A., Xu,D., Feng,Z.,
Chen,W., Cai,Z., Darnay,B., Gu,W. and Lin,H.K.
TITLE Cycles of ubiquitination and deubiquitination critically regulate
growth factor-mediated activation of Akt signaling
JOURNAL Sci Signal 6 (257), RA3 (2013)
PUBMED 23300340
REMARK GeneRIF: CYLD is a molecular switch for cycles of ubiquitination
and deubiquitination that critically regulate growth
factor-mediated activation of Akt signaling.
Publication Status: Online-Only
REFERENCE 2 (bases 1 to 8608)
AUTHORS Ke,H., Augustine,C.K., Gandham,V.D., Jin,J.Y., Tyler,D.S.,
Akiyama,S.K., Hall,R.P. and Zhang,J.Y.
TITLE CYLD inhibits melanoma growth and progression through suppression
of the JNK/AP-1 and beta1-integrin signaling pathways
JOURNAL J. Invest. Dermatol. 133 (1), 221-229 (2013)
PUBMED 22832488
REMARK GeneRIF: these findings demonstrate that the JNK/activator protein
1 signaling pathway underlies the melanoma growth and metastasis
that are associated with CYLD loss of function.
REFERENCE 3 (bases 1 to 8608)
AUTHORS Nagy,N., Farkas,K., Kinyo,A., Nemeth,I.B., Kis,E., Varga,J.,
Bata-Csorgo,Z., Kemeny,L. and Szell,M.
TITLE A novel missense mutation of the CYLD gene identified in a
Hungarian family with Brooke-Spiegler syndrome
JOURNAL Exp. Dermatol. 21 (12), 967-969 (2012)
PUBMED 23171463
REMARK GeneRIF: We investigated a Hungarian Brooke Spiegler syndrome
pedigree with two affected members, demonstrating a novel missense
mutation (c.2613C>G; p.His871Gln) in exon 19 within the
ubiquitin-specific protease domain of the encoded protein.
REFERENCE 4 (bases 1 to 8608)
AUTHORS Chu,Y., Soberon,V., Glockner,L., Beyaert,R., Massoumi,R., van
Loo,G., Krappmann,D. and Schmidt-Supprian,M.
TITLE A20 and CYLD do not share significant overlapping functions during
B cell development and activation
JOURNAL J. Immunol. 189 (9), 4437-4443 (2012)
PUBMED 23002441
REMARK GeneRIF: Lack of both CYLD and A20 do not exacerbate the
developmental defects and hyperresponsive activity of A20-deficient
B cells.
REFERENCE 5 (bases 1 to 8608)
AUTHORS Gomez-Ferreria,M.A., Bashkurov,M., Mullin,M., Gingras,A.C. and
Pelletier,L.
TITLE CEP192 interacts physically and functionally with the
K63-deubiquitinase CYLD to promote mitotic spindle assembly
JOURNAL Cell Cycle 11 (19), 3555-3558 (2012)
PUBMED 22895009
REMARK GeneRIF: CEP192 promotes robust mitotic spindle assembly by
regulating K63-polyubiquitin-mediated signaling through CYLD.
REFERENCE 6 (bases 1 to 8608)
AUTHORS Bignell,G.R., Warren,W., Seal,S., Takahashi,M., Rapley,E.,
Barfoot,R., Green,H., Brown,C., Biggs,P.J., Lakhani,S.R., Jones,C.,
Hansen,J., Blair,E., Hofmann,B., Siebert,R., Turner,G., Evans,D.G.,
Schrander-Stumpel,C., Beemer,F.A., van Den Ouweland,A., Halley,D.,
Delpech,B., Cleveland,M.G., Leigh,I., Leisti,J. and Rasmussen,S.
TITLE Identification of the familial cylindromatosis tumour-suppressor
gene
JOURNAL Nat. Genet. 25 (2), 160-165 (2000)
PUBMED 10835629
REFERENCE 7 (bases 1 to 8608)
AUTHORS Fenske,C., Banerjee,P., Holden,C. and Carter,N.
TITLE Brooke-Spiegler syndrome locus assigned to 16q12-q13
JOURNAL J. Invest. Dermatol. 114 (5), 1057-1058 (2000)
PUBMED 10792569
REFERENCE 8 (bases 1 to 8608)
AUTHORS Thomson,S.A., Rasmussen,S.A., Zhang,J. and Wallace,M.R.
TITLE A new hereditary cylindromatosis family associated with CYLD1 on
chromosome 16
JOURNAL Hum. Genet. 105 (1-2), 171-173 (1999)
PUBMED 10480375
REFERENCE 9 (bases 1 to 8608)
AUTHORS Biggs,P.J., Chapman,P., Lakhani,S.R., Burn,J. and Stratton,M.R.
TITLE The cylindromatosis gene (cyld1) on chromosome 16q may be the only
tumour suppressor gene involved in the development of cylindromas
JOURNAL Oncogene 12 (6), 1375-1377 (1996)
PUBMED 8649842
REFERENCE 10 (bases 1 to 8608)
AUTHORS Biggs,P.J., Wooster,R., Ford,D., Chapman,P., Mangion,J., Quirk,Y.,
Easton,D.F., Burn,J. and Stratton,M.R.
TITLE Familial cylindromatosis (turban tumour syndrome) gene localised to
chromosome 16q12-q13: evidence for its role as a tumour suppressor
gene
JOURNAL Nat. Genet. 11 (4), 441-443 (1995)
PUBMED 7493027
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB119480.1, BC012342.1,
AJ250014.1, AB020656.2, DA157717.1, DA940312.1 and AL050166.1.
Summary: This gene is encodes a cytoplasmic protein with three
cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains
that functions as a deubiquitinating enzyme. Mutations in this gene
have been associated with cylindromatosis, multiple familial
trichoepithelioma, and Brooke-Spiegler syndrome. Alternate
transcriptional splice variants, encoding different isoforms, have
been characterized. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (3) has an alternate 5' terminal
exon, and lacks one exon in the 5' UTR and another in-frame exon in
the coding region, compared to variant 1, resulting in a shorter
protein (isoform 2), compared to isoform 1. Variants 2 and 3 encode
the same isoform.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC012342.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025089 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-26 DB119480.1 1-26
27-3503 BC012342.1 1-3477
3504-5131 AJ250014.1 3602-5229
5132-5144 AB020656.2 5276-5288
5145-5273 AJ250014.1 5243-5371
5274-5664 DA157717.1 182-572
5665-6251 DA940312.1 9-595
6252-8608 AL050166.1 315-2671
FEATURES Location/Qualifiers
source 1..8608
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q12.1"
gene 1..8608
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="cylindromatosis (turban tumor syndrome)"
/db_xref="GeneID:1540"
/db_xref="HGNC:2584"
/db_xref="MIM:605018"
exon 1..99
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
exon 100..179
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
exon 180..806
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 203..204
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="a"
/db_xref="dbSNP:67190903"
variation 212
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369755094"
misc_feature 279..281
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="upstream in-frame stop codon"
variation 283
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190977024"
CDS 303..3164
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/EC_number="3.4.19.12"
/note="isoform 2 is encoded by transcript variant 3;
ubiquitin specific peptidase like 2; ubiquitin
thiolesterase CYLD; probable ubiquitin carboxyl-terminal
hydrolase CYLD; ubiquitin-specific-processing protease
CYLD; deubiquitinating enzyme CYLD; ubiquitin thioesterase
CYLD"
/codon_start=1
/product="ubiquitin carboxyl-terminal hydrolase CYLD
isoform 2"
/protein_id="NP_001035877.1"
/db_xref="GI:109637776"
/db_xref="CCDS:CCDS42164.1"
/db_xref="GeneID:1540"
/db_xref="HGNC:2584"
/db_xref="MIM:605018"
/translation="
MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRIPSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLSKGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGVYQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGDTMQVELPPLEINSRVSLKVGETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHINDIIPESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNGSSVDSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFDRSSPPLQPPPVNSLTTENRFHSLPFSLTKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKENPPFYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK
"
misc_feature 681..911
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="Cytoskeleton-associated proteins (CAPs) are
involved in the organisation of microtubules and
transportation of vesicles and organelles along the
cytoskeletal network; Region: CAP_GLY; smart01052"
/db_xref="CDD:198120"
misc_feature 996..1211
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="CAP-Gly domain; Region: CAP_GLY; pfam01302"
/db_xref="CDD:201721"
misc_feature 1473..1700
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NQC7.1);
Region: Interaction with TRAF2"
misc_feature 1488..1490
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1545..1547
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9NQC7.1); phosphorylation site"
misc_feature 1701..1955
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NQC7.1);
Region: Interaction with IKBKG/NEMO"
misc_feature 1707..1913
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="Cytoskeleton-associated proteins (CAPs) are
involved in the organisation of microtubules and
transportation of vesicles and organelles along the
cytoskeletal network; Region: CAP_GLY; smart01052"
/db_xref="CDD:198120"
misc_feature 2322..3137
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="A subfamily of Peptidase C19. Peptidase C19
contains ubiquitinyl hydrolases. They are intracellular
peptidases that remove ubiquitin molecules from
polyubiquinated peptides by cleavage of isopeptide bonds.
They hydrolyze bonds involving the carboxyl...; Region:
Peptidase_C19N; cd02670"
/db_xref="CDD:73076"
misc_feature order(2904..2906,2961..2963)
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="active site"
/db_xref="CDD:73076"
variation 358
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374624194"
variation 372
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368114885"
variation 389
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:34564491"
variation 428
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:202119806"
variation 460
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375455772"
variation 510
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369619557"
variation 515
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373198684"
variation 541
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201666656"
variation 546
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376006417"
variation 680
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369238843"
variation 803
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373896011"
exon 807..1109
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 816
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201836260"
variation 820
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:12599808"
variation 836
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377383082"
variation 840
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:370450747"
variation 871
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:374118770"
variation 884
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201431389"
variation 896
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:367580462"
variation 920
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371338061"
variation 937
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375434282"
variation 974
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:372885659"
variation 977
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:184354524"
variation 998
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:375486280"
variation 1061
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372020998"
exon 1110..1215
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1193
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140033230"
variation 1200
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377066412"
variation 1211
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202154956"
exon 1216..1314
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1225
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200271412"
variation 1253
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:369147527"
variation 1276
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372199798"
variation 1298
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374929114"
exon 1315..1431
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1334
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:369452792"
variation 1338
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373172148"
exon 1432..1811
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1456
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199606039"
variation 1459
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200759332"
variation 1465
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138976689"
variation 1482
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:149427272"
variation 1483
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370428449"
variation 1485
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:202120212"
variation 1502
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371382898"
variation 1518
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375579250"
variation 1585
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200494719"
variation 1616
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:368393884"
variation 1624
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:371683706"
variation 1649
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200886685"
variation 1653
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200451975"
variation 1658
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371867434"
variation 1766
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:75757530"
variation 1775
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369789110"
exon 1812..1977
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1843
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:201523761"
exon 1978..2119
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2018
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373031051"
exon 2120..2242
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2213
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:182210792"
exon 2243..2334
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2312
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373899187"
exon 2335..2401
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
exon 2402..2534
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2438
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200905032"
variation 2465
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:373971257"
variation 2533
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:121908389"
exon 2535..2643
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2537
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370702435"
variation 2565
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:121908388"
variation 2612
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199912760"
exon 2644..2762
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2679
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374104988"
variation 2683
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199624138"
variation 2705
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2066852"
variation 2727
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371330250"
exon 2763..2979
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2831
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:376293566"
variation 2846
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370020837"
variation 2882
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201868355"
variation 2891
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200765362"
variation 2899
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200154154"
variation 2912
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:373541485"
exon 2980..8591
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 3099
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:121908390"
variation 3107
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199632232"
variation 3175
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373881703"
variation 3198
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:376027595"
variation 3211
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:116979331"
STS 3221..3510
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="SHGC-60837"
/db_xref="UniSTS:67819"
variation 3303
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148107725"
STS 3309..3497
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="RH64884"
/db_xref="UniSTS:83726"
polyA_signal 3516..3521
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
polyA_site 3545
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
variation 3546
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142580891"
variation 3943
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190787930"
variation 3995
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144877731"
variation 4001
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3743781"
variation 4005
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:117537927"
variation 4086
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375222421"
variation 4139
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:369791294"
STS 4181..4322
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="RH94254"
/db_xref="UniSTS:88351"
variation 4217
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:147959249"
variation 4266
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:141088048"
variation 4286
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114552144"
variation 4355
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:146935881"
variation 4406
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:150937990"
variation 4409
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192470603"
variation 4505
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:140767609"
variation 4591
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150124371"
STS 4621..5321
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="CYLD__4662"
/db_xref="UniSTS:471409"
variation 4739
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:184344245"
variation 4813
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:188778402"
variation 4963
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138586985"
variation 4995
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:181246559"
variation 5086
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:141752920"
variation 5148
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:145519346"
variation 5269..5271
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="gga"
/db_xref="dbSNP:75414200"
variation 5271
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="a"
/db_xref="dbSNP:111804189"
variation 5272
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:79868875"
variation 5284..5286
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="aaa"
/db_xref="dbSNP:74757288"
variation 5288
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199826833"
variation 5326
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:138143910"
variation 5400
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:57638820"
variation 5435
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:185590115"
variation 5475..5477
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="ttc"
/db_xref="dbSNP:370824949"
variation 5499
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:9646285"
variation 5533
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:16948829"
variation 5546
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189512578"
variation 5615
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368296872"
variation 5697
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:371051271"
STS 5722..5890
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="RH48312"
/db_xref="UniSTS:65489"
variation 5770
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="t"
/db_xref="dbSNP:371917388"
variation 5779
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:181056407"
variation 5840
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:76888453"
variation 5874
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141928186"
polyA_signal 5934..5939
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
variation 5952..5953
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="tg"
/db_xref="dbSNP:375257369"
polyA_site 5955
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
variation 6234
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144667145"
variation 6247
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:185943382"
variation 6276
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="t"
/db_xref="dbSNP:149875014"
variation 6299
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:374305356"
variation 6403
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:34088926"
variation 6416
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:375925980"
variation 6473
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192317768"
variation 6587
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:183255879"
variation 6619
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:186163821"
variation 6633
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:111951225"
variation 6727
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190533095"
variation 6757
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368698335"
variation 6761
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372708124"
variation 6778
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:372370285"
variation 6843
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141888517"
variation 6844
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:374723746"
variation 6860
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:182950511"
variation 6903
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:16948836"
variation 6920
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:188392607"
variation 7037
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192669779"
variation 7110
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:367816704"
variation 7119
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371569379"
variation 7244
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:183024011"
variation 7318
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376037772"
variation 7445
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:187441896"
variation 7725
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:17314948"
variation 7731
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:113748745"
variation 7740
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373507820"
variation 7779..7780
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="g"
/db_xref="dbSNP:34262697"
variation 7873
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192535029"
variation 8004
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150641352"
variation 8049
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:184571054"
variation 8052..8053
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="at"
/db_xref="dbSNP:143814807"
variation 8213
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:187446083"
variation 8401
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192242759"
variation 8436
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140875917"
STS 8443..8546
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="SGC32374"
/db_xref="UniSTS:28941"
polyA_signal 8568..8573
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
polyA_site 8591
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
ORIGIN
gtcggaggtaaatactagggcggtgggtgtggggagccggggccggcccgggacgcgggctggggagccggggcgaggggcgacgccccgccgcccgagtttccccctttctagggtgaggatggttctacacagccacccggagttccttagttgaaaggtgcgccctgctgtgacagcatggacaccacgttgctgaaaacatgctttgggactgccactgaatttatcttttgcggttttatgacaaagttattagtagtttcccttttttgaattagtattttgaagttaatatcacaatgagttcaggcttatggagccaagaaaaagtcacttcaccctactgggaagagcggattttttacttgcttcttcaagaatgcagcgttacagacaaacaaacacaaaagctccttaaagtaccgaagggaagtataggacagtatattcaagatcgttctgtggggcattcaaggattccttctgcaaaaggcaagaaaaatcagattggattaaaaattctagagcaacctcatgcagttctctttgttgatgaaaaggatgttgtagagataaatgaaaagttcacagagttacttttggcaattaccaattgtgaggagaggttcagcctgtttaaaaacagaaacagactaagtaaaggcctccaaatagacgtgggctgtcctgtgaaagtacagctgagatctggggaagaaaaatttcctggagttgtacgcttcagaggacccctgttagcagagaggacagtctccggaatattctttggagttgaattgctggaagaaggtcgtggtcaaggtttcactgacggggtgtaccaagggaaacagctttttcagtgtgatgaagattgtggcgtgtttgttgcattggacaagctagaactcatagaagatgatgacactgcattggaaagtgattacgcaggtcctggggacacaatgcaggtcgaacttcctcctttggaaataaactccagagtttctttgaaggttggagaaacaatagaatctggaacagttatattctgtgatgttttgccaggaaaagaaagcttaggatattttgttggtgtggacatggataaccctattggcaactgggatggaagatttgatggagtgcagctttgtagttttgcgtgtgttgaaagtacaattctattgcacatcaatgatatcatcccagagagtgtgacgcaggaaaggaggcctcccaaacttgcctttatgtcaagaggtgttggggacaaaggttcatccagtcataataaaccaaaggctacaggatctacctcagaccctggaaatagaaacagatctgaattattttataccttaaatgggtcttctgttgactcacaaccacaatccaaatcaaaaaatacatggtacattgatgaagttgcagaagaccctgcaaaatctcttacagagatatctacagactttgaccgttcttcaccaccactccagcctcctcctgtgaactcactgaccaccgagaacagattccactctttaccattcagtctcaccaagatgcccaataccaatggaagtattggccacagtccactttctctgtcagcccagtctgtaatggaagagctaaacactgcacccgtccaagagagtccacccttggccatgcctcctgggaactcacatggtctagaagtgggctcattggctgaagttaaggagaaccctcctttctatggggtaatccgttggatcggtcagccaccaggactgaatgaagtgctcgctggactggaactggaagatgagtgtgcaggctgtacggatggaaccttcagaggcactcggtatttcacctgtgccctgaagaaggcgctgtttgtgaaactgaagagctgcaggcctgactctaggtttgcatcattgcagccggtttccaatcagattgagcgctgtaactctttagcatttggaggctacttaagtgaagtagtagaagaaaatactccaccaaaaatggaaaaagaaggcttggagataatgattgggaagaagaaaggcatccagggtcattacaattcttgttacttagactcaaccttattctgcttatttgcttttagttctgttctggacactgtgttacttagacccaaagaaaagaacgatgtagaatattatagtgaaacccaagagctactgaggacagaaattgttaatcctctgagaatatatggatatgtgtgtgccacaaaaattatgaaactgaggaaaatacttgaaaaggtggaggctgcatcaggatttacctctgaagaaaaagatcctgaggaattcttgaatattctgtttcatcatattttaagggtagaacctttgctaaaaataagatcagcaggtcaaaaggtacaagattgttacttctatcaaatttttatggaaaaaaatgagaaagttggcgttcccacaattcagcagttgttagaatggtcttttatcaacagtaacctgaaatttgcagaggcaccatcatgtctgattattcagatgcctcgatttggaaaagactttaaactatttaaaaaaatttttccttctctggaattaaatataacagatttacttgaagacactcccagacagtgccggatatgtggagggcttgcaatgtatgagtgtagagaatgctacgacgatccggacatctcagctggaaaaatcaagcagttttgtaaaacctgcaacactcaagtccaccttcatccgaagaggctgaatcataaatataacccagtgtcacttcccaaagacttacccgactgggactggagacacggctgcatcccttgccagaatatggagttatttgctgttctctgcatagaaacaagccactatgttgcttttgtgaagtatgggaaggacgattctgcctggctcttctttgacagcatggccgatcgggatggtggtcagaatggcttcaacattcctcaagtcaccccatgcccagaagtaggagagtacttgaagatgtctctggaagacctgcattccttggactccaggagaatccaaggctgtgcacgaagactgctttgtgatgcatatatgtgcatgtaccagagtccaacaatgagtttgtacaaataactggggtcatcgggaaaggcaaagaaactgaaggcagagtcctaacgttgcatcttattcgagctggcagttctgttcacgtccattgccggcaatggatgtctttgtggtgatgatccttcagaaaaggatgcctctgtttaaaaacaaattgcttttgtgtccctgaagtatttaataagaagcattttgcactctagaaagtatgtttgtgttggttttttaagaagtctaaatgaagttattaatacctgaagctttaagttaagtgcattgatcatatgatatttttggaagcatacaattttaattgtggaagtttaaagcctcttttagtccattgagaatgtaaataaatgtgtcttctttatggaccaaggatatgaaatcatttttcttttgtagctaacggttgccttgaggaagaaataatttggttttattaagagtctactctcaatccagttattagagatgtactgagtttgatttgttaatcctttctatatactgctgatcttgcatgtctacaatctgctcagtttttctgtgtttctgcaatagtggtcagaaaaatacttaaattcccttaatggtgttgttttctatttgttctggttttgagataaatgagtgattctgtccccaaatgtccatttttgaagtgattttcctggaggattagggtatttagcagttgaagctcttcattcatagtagttactgtcagctaacaggttttttaaggcttttaactattaatattttatggaatggggcaaagtaaattgatgaaagaattggagtgataatagtcctttacaaacatacagtccataagaaaatgaatttggcatatagaattattacaatttcctgggagagatggatatttaaacctctattattttagacaagactgtctagaacttaagtttgatctgtcagccagtactcccattaaattcagtgtagtttcacttgatagaatcagatatgttatcgaaatgttagcagcagcttcatcctccttctgattaaagtaagtagaaatgggatgttttgtttaataacagccatagtgtgtgtttagaccacagcggatgttgtagaccaggaccatagatgatacatgtcagtgctgtggaatgtgcattctctgagtgttgttttgtggtatcattgtctttcctgaatgactttctaactgtgcagaaaggcagaaaagtcatcatatgtatatgtcatatgactttataaaatatttaatgtgacaaaaagtggaaagaatctttacaaaccctgcaattacttttttaaaggcacttttactctttggttttatcattccattttgctaatatttactagctttataaattacagtaaggtacaaaaactcatcttgtaatattttcatttttgaagtgaaaaagtacatatattttgcacaaggttttatactgctaagtgcttggttggggtggtgagatgatgattagatcaggggtgaggctgagagactctgggtttagggctagccctgcctccatctcccttgggtaaaatgaagggtgtggggtaaaagatgcataaggccttttctagctctgacagcctagaagtccaatcaccctgtaataaatatgtgttgaatgaagaaatgggtgaatgagcttgtcaatgtgattttaaaaaattgactacctggaggaatgattaggaatctaaatgaagccagccctcggtatctgcaggtttctcatccatggattcaaccaactgcaaatggaaaatacgattttttttaaaaaaaggatggttacatccgtattgaacatgtacagacttttttcttgtcattattctctgaacaatacaagaactctttatgtagcatttacatttattaggtattataagtaatctagagattatttaattaaaatatacaggaggatgtgtgtcagttatatgcaaattctgtaccattttgtatcagggaattgagcatcttcagatgttggtatctgcagggatcctggaaccaaacccctgcagatactaagggctgacgatctaggtaagactggatttaacagttggaaaaaaaaaaaaaaaaggagagagaagacagttcctttcctgtagaaattaaaacaaaatacaaattgaggaagctctgctacccaggctgtcatggtagagaacttgaagaagacctgtttggatggacacctggtttcaaaagtcaggtgtggagactgttaaatgggagggcctcatccataaatgatttctggcaacgtcttcttcaggtggagcttgacgtctttttaatgttacttggggagggagtgctcattaagggatgccagggccagctctggtggttcctggggaggctgcgtccttccctgcttctgcatgtcatgaggcagcaggaaggtttcccctgcacctgtctgtcctggctccctctgggtagccccctactgttctgtgcttcagcacagcctggtttgtcaagaggcacatagttggggctgggctgcatggcacaggggcttatgtgcctgctggttatttaattttcagccttaagttttctttaatattttcctgttggctatttaaaggttttggttatcttttattccttatctacaatcaagatgacaatgtaattgaattatcttatttataacacggttcgtgattcatgattcatgattacaagtagaaaatatgtcatgttcctcacctccaaataaatatgtgtgtgtctgtgtgtgtgtatatatgtatgtggcggagagggagagagtggggaaggagagcagtgttatcatacatagagaggctaaatgtgtcccatccctcactgtcagctttataaaggagtttgactccatccacagaagaatgttttataagactaggaaaacacgttgaaaactaggataaacagcaacaaaaatcaactaaatatgttgttactgttgctaaggattttctccttagaataatttaggatttttaaaaatttctgtttgccaaatgctgtagataaatggccagattcttcctatccctaggattcctttattattttttttcacagattttgagaacaagggggagagatagtatggaagattaagattccattaatcttatagaactgtgttgtcacccaaattcctgcttgtttgaacatggcatcttcatagattcaggattcactaccctctatagctggatcttgaaaattatctggccagataattttgcatctgcttggatgattgtagactgagatgtgagtggaggataaagtattagacttttgctgagtaactgccaaccaagaagtatttatcggacacttactaggtgcctaggattgtatcagagggaatatgaaatgtgtccctgccctacctagttttaacgacagaatatctattaaaggctacttagctgaagggtaagggtgacaggtctaggggaagctttgggaggtggtgtgctgtgacagaaaaagtggcagagtagggacgagagacctgcattctagccctgtttctgtcacttgctctgtacacttagacaacagcttgacctcttgagctttagtttcctcctctgcataatgagagggttagactactgaattgtatgggaaaaaaatacaaattcctgggtcctaggccatgcctgctgaatccgactgttcaggaagaggcctaggaaatctgtgagggaatccccaggggaatctcgtgaccagccaggtgtgaaatctgctaactggaagatctcaaagcttccttcactttttgtgattttgtggtcatgtaacgttactgtattattctacgtaaatgtgggtacttggatgtttatcatactgtttctctgtgtttacatactaatttgtgtaagaaatgcattttagtctgtgtacctcaacctgctgtttgtttcctagaggtgttagtagtctttaaatacaagtaagacttaagaggatatttgatgttatttacctggatattttcttccccttttatttatttagaggaaattgagattctaggagccaaaaaaatgaaaacaaaattctaaggcaaagttaaagaaaaaaattacattatttcttaccatttgctactttataatgaaaatttaaaaattatatgggaagatttttctctgggataacaaatccttgtcataaagtaagaggtctttttaaagtaggtaggctataaggcctgtaatttaaaataatactcctttctctagggtttggtgcaattctccattaatgaagataacatttgaattccccaaagcaggtgaggagtcggggaggagaaagcgatgttaaaatgaaaactcactgcaaaagaggaggcagaggaagaaggaatgtaaaccccttaaagcagatgtgtgtggggccttatgaagaccaggattctgcgggtgtcaggggattgcccctcttgacagagactagggttttagactgaggcttcctgcagggtgttcgcattgcccttctccgttccccttcagacctttctggggagaagaggtgggaggaggggagaaagactgttcatcttattctgaatcctggagcagctgaaggttttctcttgagtcaggatgcagtggtaatgcattaaccagcaagtgtggccaaggataatgaaaaagtgggaaaggaaggtcctcctcctccctgattgtagcatccagcagtctctgtagccaggttactcaagaaccacatttgatttcctggccctttgccttggcagtgatggcatttttatttcactgtgttttaaagtcttcatttatttttataacatgggttagggagaagggccacaaatggagggattgtcctttcaagcaccacagcttcagataaaattagtactttcaaatattgtccactttaacttaaaaaattctagagggattatattggagactcaactgcccttggttttagtttataaaatggcctagtactgtggaattttaattttagaaagtcttagcatcagatcataaacattcattaaaagaactcacatcccatctgaaacttcccaggggagttgggattcttagtagattggtagaaaggggctcattttctactgcatttcccatttttggtatcttgttcagcatgttttatttttatttcttgtctgcagaacatcctatatttatgagaacattctttaagaagaccaccacatagaataccccttcctatcagctcgctctgatttagccttaattttgttaaattttttagagatgaatgaagtgctgctgtggaaagaaatgtacatatactatttctgtatcattaaaattacatttttatggttcaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:1540 -> Molecular function: GO:0004221 [ubiquitin thiolesterase activity] evidence: IEA
GeneID:1540 -> Molecular function: GO:0004843 [ubiquitin-specific protease activity] evidence: IDA
GeneID:1540 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:1540 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IDA
GeneID:1540 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IPI
GeneID:1540 -> Molecular function: GO:0070064 [proline-rich region binding] evidence: IPI
GeneID:1540 -> Biological process: GO:0006511 [ubiquitin-dependent protein catabolic process] evidence: IEA
GeneID:1540 -> Biological process: GO:0006917 [induction of apoptosis] evidence: IDA
GeneID:1540 -> Biological process: GO:0007049 [cell cycle] evidence: IEA
GeneID:1540 -> Biological process: GO:0007346 [regulation of mitotic cell cycle] evidence: IMP
GeneID:1540 -> Biological process: GO:0016055 [Wnt receptor signaling pathway] evidence: IEA
GeneID:1540 -> Biological process: GO:0032088 [negative regulation of NF-kappaB transcription factor activity] evidence: IDA
GeneID:1540 -> Biological process: GO:0032480 [negative regulation of type I interferon production] evidence: TAS
GeneID:1540 -> Biological process: GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway] evidence: TAS
GeneID:1540 -> Biological process: GO:0042347 [negative regulation of NF-kappaB import into nucleus] evidence: IDA
GeneID:1540 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:1540 -> Biological process: GO:0070423 [nucleotide-binding oligomerization domain containing signaling pathway] evidence: TAS
GeneID:1540 -> Biological process: GO:0070507 [regulation of microtubule cytoskeleton organization] evidence: IMP
GeneID:1540 -> Biological process: GO:0070536 [protein K63-linked deubiquitination] evidence: IDA
GeneID:1540 -> Biological process: GO:0090090 [negative regulation of canonical Wnt receptor signaling pathway] evidence: IMP
GeneID:1540 -> Biological process: GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] evidence: IMP
GeneID:1540 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
GeneID:1540 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:1540 -> Cellular component: GO:0005881 [cytoplasmic microtubule] evidence: IDA
GeneID:1540 -> Cellular component: GO:0030496 [midbody] evidence: IDA
GeneID:1540 -> Cellular component: GO:0031234 [extrinsic to internal side of plasma membrane] evidence: IDA
GeneID:1540 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_001035877 -> EC 3.4.19.12
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.