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2019-03-25 15:06:23, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001042405            6832 bp    mRNA    linear   PRI 09-JUN-2013
DEFINITION  Homo sapiens centrosomal protein 170kDa (CEP170), transcript
            variant gamma, mRNA.
ACCESSION   NM_001042405 XM_001125768
VERSION     NM_001042405.1  GI:109255231
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6832)
  AUTHORS   Welburn,J.P. and Cheeseman,I.M.
  TITLE     The microtubule-binding protein Cep170 promotes the targeting of
            the kinesin-13 depolymerase Kif2b to the mitotic spindle
  JOURNAL   Mol. Biol. Cell 23 (24), 4786-4795 (2012)
   PUBMED   23087211
  REMARK    GeneRIF: Data indicate that Cep170 association with the C-terminus
            of Kif2b enhances localization of Kif2b to the spindle.
REFERENCE   2  (bases 1 to 6832)
  AUTHORS   McCauley,J.L., Zuvich,R.L., Bradford,Y., Kenealy,S.J.,
            Schnetz-Boutaud,N., Gregory,S.G., Hauser,S.L., Oksenberg,J.R.,
            Mortlock,D.P., Pericak-Vance,M.A. and Haines,J.L.
  TITLE     Follow-up examination of linkage and association to chromosome 1q43
            in multiple sclerosis
  JOURNAL   Genes Immun. 10 (7), 624-630 (2009)
   PUBMED   19626040
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 6832)
  AUTHORS   Kim,J.E., Tannenbaum,S.R. and White,F.M.
  TITLE     Global phosphoproteome of HT-29 human colon adenocarcinoma cells
  JOURNAL   J. Proteome Res. 4 (4), 1339-1346 (2005)
   PUBMED   16083285
REFERENCE   4  (bases 1 to 6832)
  AUTHORS   Guarguaglini,G., Duncan,P.I., Stierhof,Y.D., Holmstrom,T.,
            Duensing,S. and Nigg,E.A.
  TITLE     The forkhead-associated domain protein Cep170 interacts with
            Polo-like kinase 1 and serves as a marker for mature centrioles
  JOURNAL   Mol. Biol. Cell 16 (3), 1095-1107 (2005)
   PUBMED   15616186
  REMARK    GeneRIF: Cep170 interacts with Polo-like kinase 1 in mature
            centrioles.
REFERENCE   5  (bases 1 to 6832)
  AUTHORS   Jin,J., Smith,F.D., Stark,C., Wells,C.D., Fawcett,J.P.,
            Kulkarni,S., Metalnikov,P., O'Donnell,P., Taylor,P., Taylor,L.,
            Zougman,A., Woodgett,J.R., Langeberg,L.K., Scott,J.D. and Pawson,T.
  TITLE     Proteomic, functional, and domain-based analysis of in vivo 14-3-3
            binding proteins involved in cytoskeletal regulation and cellular
            organization
  JOURNAL   Curr. Biol. 14 (16), 1436-1450 (2004)
   PUBMED   15324660
REFERENCE   6  (bases 1 to 6832)
  AUTHORS   Andersen,J.S., Wilkinson,C.J., Mayor,T., Mortensen,P., Nigg,E.A.
            and Mann,M.
  TITLE     Proteomic characterization of the human centrosome by protein
            correlation profiling
  JOURNAL   Nature 426 (6966), 570-574 (2003)
   PUBMED   14654843
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BP349680.1, BP349206.1,
            AB022659.1, AC092782.2 and CB410835.1.
            On Sep 20, 2006 this sequence version replaced gi:113412733.
            
            Summary: The product of this gene is a component of the centrosome,
            a non-membraneous organelle that functions as the major
            microtubule-organizing center in animal cells. During interphase,
            the encoded protein localizes to the sub-distal appendages of
            mature centrioles, which are microtubule-based structures thought
            to help organize centrosomes. During mitosis, the protein
            associates with spindle microtubules near the centrosomes. The
            protein interacts with and is phosphorylated by polo-like kinase 1,
            and functions in maintaining microtubule organization and cell
            morphology. The human genome contains a putative transcribed
            pseudogene. Several alternatively spliced transcript variants of
            this gene have been found, but the full-length nature of some of
            these variants has not been determined. [provided by RefSeq, Jul
            2008].
            
            Transcript Variant: This variant (gamma, also known as 3) has
            multiple differences in the coding region but maintains the reading
            frame, compared to variant alpha, resulting in a shorter protein
            (isoform gamma), compared to isoform alpha.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC146790.1, AB007939.1 [ECO:0000331]
            RNAseq introns       :: mixed/partial sample support ERS025081,
                                    ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-274               BP349680.1         1-274
            275-634             BP349206.1         222-581
            635-1044            AB022659.1         280-689
            1045-1045           AC092782.2         81447-81447         c
            1046-6562           AB022659.1         691-6207
            6563-6832           CB410835.1         1-270
FEATURES             Location/Qualifiers
     source          1..6832
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..6832
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /note="centrosomal protein 170kDa"
                     /db_xref="GeneID:9859"
                     /db_xref="HGNC:28920"
                     /db_xref="MIM:613023"
     exon            1..367
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            368..513
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    370..372
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /note="upstream in-frame stop codon"
     CDS             409..4791
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /note="isoform gamma is encoded by transcript variant
                     gamma; XRCC5 binding protein; KARP-1-binding protein"
                     /codon_start=1
                     /product="centrosomal protein of 170 kDa isoform gamma"
                     /protein_id="NP_001035864.1"
                     /db_xref="GI:109255232"
                     /db_xref="CCDS:CCDS44338.1"
                     /db_xref="GeneID:9859"
                     /db_xref="HGNC:28920"
                     /db_xref="MIM:613023"
                     /translation="
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQDQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
"
     misc_feature    436..702
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /note="Forkhead associated domain (FHA); found in
                     eukaryotic and prokaryotic proteins. Putative nuclear
                     signalling domain. FHA domains may bind phosphothreonine,
                     phosphoserine and sometimes phosphotyrosine. In
                     eukaryotes, many FHA domain-containing proteins...;
                     Region: FHA; cd00060"
                     /db_xref="CDD:28942"
     misc_feature    <442..678
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /note="FOG: FHA domain [Signal transduction mechanisms];
                     Region: COG1716"
                     /db_xref="CDD:31902"
     misc_feature    order(487..489,520..522,526..531,595..603)
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /note="phosphopeptide binding site; other site"
                     /db_xref="CDD:28942"
     misc_feature    1474..1476
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q5SW79.1); phosphorylation site"
     misc_feature    1474..1476
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1483..1485
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q5SW79.1); phosphorylation site"
     misc_feature    1483..1485
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1498..1500
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphotyrosine; propagated from
                     UniProtKB/Swiss-Prot (Q5SW79.1); phosphorylation site"
     misc_feature    1537..1539
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1993..1995
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1996..1998
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2002..2004
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2011..2013
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2020..2022
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2626..2628
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2749..2751
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2896..2898
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2902..2904
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2911..2913
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2923..2925
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    3025..3027
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    3448..3450
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    4597..4599
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    4600..4602
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     exon            514..603
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            604..682
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            683..741
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            742..904
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            905..1039
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            1040..1516
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            1517..1680
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            1681..1830
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     variation       1729
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34312127"
     exon            1831..1957
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            1958..3790
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     variation       2283
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2789194"
     variation       2327
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3766664"
     STS             3017..3149
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /standard_name="G33981"
                     /db_xref="UniSTS:38719"
     STS             3056..3231
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /standard_name="D4S1286"
                     /db_xref="UniSTS:5571"
     exon            3791..3917
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            3918..4095
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            4096..4266
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            4267..4355
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            4356..4449
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            4450..4501
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     exon            4502..6812
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /inference="alignment:Splign:1.39.8"
     variation       4747
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11147"
     variation       4755
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10881"
     variation       4831
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1046118"
     variation       4907
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2787270"
     variation       4954
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2787271"
     STS             5249..5408
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /standard_name="G34957"
                     /db_xref="UniSTS:117667"
     STS             5249..5408
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /standard_name="RH67046"
                     /db_xref="UniSTS:90613"
     variation       5496
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1062985"
     STS             5695..6607
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /standard_name="KAB__6501"
                     /db_xref="UniSTS:464008"
     variation       5800
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2787273"
     variation       6280
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2789211"
     STS             6575..6788
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
                     /standard_name="RH80002"
                     /db_xref="UniSTS:83593"
     polyA_signal    6790..6795
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
     polyA_site      6812
                     /gene="CEP170"
                     /gene_synonym="FAM68A; KAB; KIAA0470"
ORIGIN      
gggcaagctggaaaagcgtgtgggtgagaccctcgcacaaccccttttcattgtctgtgtgtggcgcctgcgcagtaagggatcgttggaactgggcaggaggggatagggtccggctcctcgccctttcccgaggcgcctgcgcactaggcagtcggtctttgccgttaccgctatgtgtggggcgtgtgtggaataacgttattgcccagcggagctgagggccccggagctcgaccgcagcggcagcgacgacaacagcggcgacgacgacgacgacgaggtggggggaggacggcgtgcgagagactcacgggacgcgacgcgccccgcctcccccgtccggtccctctctccacggtaaggggatgacgtagctttgccaaagacttagaagctaagcagaaaatgagcttaacatcctggtttttggtgagcagtggaggcactcgccacaggctgccacgagaaatgatttttgttggaagagatgactgtgagctcatgttgcagtctcgtagtgtggataagcaacacgctgtcatcaactatgatgcgtctacggatgagcatttagtgaaggatttgggcagcctcaatgggacttttgtgaatgatgtaaggattccggaacagacttatatcaccttgaaacttgaagataagctgagatttggatatgatacaaatcttttcactgtagtacaaggagaaatgagggtccctgaagaagctcttaagcatgagaagtttaccattcagcttcagttgtcccaaaaatcttcagaatcagaattatccaaatctgcaagtgccaaaagcatagattcaaaggtagcagacgctgctactgaagtgcagcacaaaactactgaagcactgaaatccgaggaaaaagccatggatatttctgctatgccccgtggtactccattatatgggcagccgtcatggtggggggatgatgaggtggatgaaaaaagagctttcaagacaaatggcaaacctgaagaaaaaaaccatgaagctggaacatcagggtgcggcatagatgccaagcaagttgaggaacaatctgcagctgcaaatgaagaagtactttttcctttctgtagggaaccaagttattttgaaatccctacaaaagaattccagcaaccatcacaaataacagaaagcactattcatgaaatcccaacaaaagacacgccaagttcccatataacaggtgcagggcatgcttcatttaccattgaatttgatgacagtaccccagggaaggtaactattagagaccatgtgacaaagtttacttctgatcagcgccacaagtccaagaagtcttctcctggaactcaagacttgctggggattcaaacaggaatgatggcacccgaaaacaaagttgctgactggctagcacaaaacaaccctcctcaaatgctatgggaaagaacagaagaggattctaaaagcattaaaagtgatgttccagtgtacttgaaaaggttgaaaggaaataaacatgatgatggtacgcaaagtgattcagagaacgctggggctcacaggcgctgtagcaaacgtgcaactcttgaggaacacttaagacgccaccattcagaacacaaaaagctacagaaggtccaggctactgaaaagcatcaagaccaagctgttgtgtttggagtagatgacaatcaggattataataggcctgttatcaacgaaaaacataaagatctaataaaagattgggctctcagttctgctgcagcagtaatggaagaaagaaaaccactgactacatctggatttcaccactcagaggaaggcacatcttcatctggaagcaaacgttgggtttcacagtgggctagtttggctgccaatcatacaaggcatgatcaagaagaaaggataatggaattttctgcacctcttcctttagagaatgagacagagatcagtgagtctggcatgacagtgagaagtactggctctgcaacttccttggctagccagggagagagaaggagacgaactcttccccagcttccaaatgaagaaaagtctcttgagagccacagagcaaaggttgtaacacagaggtcagagataggagaaaaacaagacacagaacttcaggagaaagaaacacctacacaggtataccagaaagataaacaagatgctgacagacccttgagtaaaatgaacagggcagtaaatggagagactctcaaaactggtggagataataaaaccctacttcacttaggcagctctgctcctggaaaagagaaaagtgaaactgataaggaaacttctttggtaaagcaaacattagcaaaacttcaacaacaagaacaaagggaggaggctcagtggacacctactaaattgtcttccaaaaatgtttcaggtcagacagataaatgtagggaggaaacttttaaacaagaatcacaacctccagaaaaaaattcaggacattctacaagcaaaggagacagagtggcacaaagtgagagcaagagaagaaaagctgaggaaattctgaaaagtcagactccaaagggaggagacaagaaggaatcctccaagtcattagtgcgacaagggagcttcactatagaaaaacccagcccaaacatacccatagaacttattccccatataaataaacagacttcctctactccttcttctttagcattaacatctgcaagtagaatacgagaaagaagtgagtctttggatcctgattctagtatggacacaacccttattctaaaagacacagaagcagtaatggcttttctagaagctaaactacgtgaagataataaaactgatgaaggaccagatactcccagttataatagagacaattctatttcaccagaatctgatgtagatacagctagtacaatcagtctggttactggagaaactgaaagaaagtcaacccaaaagcgaaagagtttcactagcctctataaagataggtgttccacaggttctccttccaaagatgttacaaaatcatcatcttcaggtgctagggaaaaaatggaaaagaaaacaaaaagtcgttccacagatgtgggttcaagagcagatggtcgtaaatttgttcagtccagtgggagaataagacagccctcagtagacttaacagatgatgaccaaacctctagtgtacctcattctgccatctctgatattatgtcatctgatcaagaaacttactcttgtaaacctcatggacggactccacttacctcagctgatgagcatgtacattccaaactggaaggaagtaaagtaacgaaatctaagacttctccggtggtatctggttcatctagtaaatcaaccacccttccaaggccacgacctaccaggacttccctcttgcgcagagcacgacttggtgaagcttcagacagtgaacttgctgatgctgacaaagcatctgttgcttctgaagtatccacaacaagttctacatcaaaacctcccacaggaaggcgtaacatctctcggattgatttattggctcagcctcgtagaacacgacttggctcactgtcagctcgtagtgactctgaagcaacaatttctagaagtagtgcctcttcgaggaccgcagaagccatcattagaagtggagccagactagtaccatcagataaattttctcctagaattagagctaacagtatctctcgactctcagactccaaggtcaaaagtatgacctcagctcatggctctgcttcagccctgaaaaccactcgcttgcagagcgctggatcagcaatgcctactagttcttcattcaaacaccggattaaagagcaggaagactacatccgagattggactgctcatcgagaagagatagccaggatcagccaagatcttgctctcattgctcgggagatcaacgatgtagcaggagagatagattcagtgacttcatcaggcactgcccctagtaccacagtaagcactgctgccaccacccctggctctgccatagacactagagaagaggtaggagatcttcatggagaaatgcataagttggttgatcgtgtttttgatgaaagcctcaacttccgaaagattcctccattagttcattccaaaacaccagaaggaaacaacggtcgatctggtgatccaagacctcaagcagcagagcctcccgatcacttaacaattacaaggcggagaacctggagcagggatgaagtcatgggagataatctgctgctgtcatccgtctttcagttctctaagaagataagacaatctatagataagacagctggaaagatcagaatattatttaaagacaaagatcggaattgggatgacatagaaagcaaattaagagccgaaagtgaagtccctattgtgaaaacctcaagcatggagatttcttctatcttacaggaactgaaaagagtagaaaagcagctgcaagcaatcaatgctatgattgatcctgatggaactttggaggctctgaacaacatgggatttcccagtgctatgttgccatctccaccgaaacagaagtccagccctgtgaataaccaccacagcccgggtcagacaccaacacttggccaaccagaagctagggctcttcatcctgctgctgtttcagccgcagctgaatttgagaatgctgaatctgaggctgatttcagtatacatttcaatagattcaaccccgatggggaagaggaagatgttacagtacaagaatgactttctcttgattgttgaaaaatcattacctgtggaatggctaggaatattggaagcagcatagtgttgatgtacgcaaaacaagacagcttggtcagctacaatcttggaatccctgtcttcttaattttatttatttatttttgacgtataatgtagtatatcaatcctttcaaactatttagataaccacttgatgcacaaataggaaaaagcagattgtggcagtgtcgccttttgtggttttatgattttcaaattgaatttaatgattacaccctttcccttcatagatcttttttcttttttttaagccatgctgtgacctacaagcaaactaaatagccaacatttctgaacccctaagtctcctgtgccaagctgctccctgaaatggacttcttcatctgtacagatttgttaaaccattctatttgcttcttaataataggatttatattagtactcattaccattggacacaatgacataagtactctccacagtaaagcagacctttcacaacagtcactctgtgtcctaaaattttccaacatagatgtgatttatataactttgttgatacgtaaattgtcttggggtttacggaaattaactattatgtttgcactaagatttgctgggagtggtaggtggacatatctatatatcaataaggactaaccgtcttttttgtacataggagattgataatactgtatttgttttaagcccacagtgttttactccactttcaaaaagatcaatttggcactttttttcattttttttaatggaaataagatttggtctctcattttaggttaaatgataactagaaagattaaactagacagatagtttaggtggagtatatttttaaaactcagaacatgtatattggtcctgtgttaccaagtttatatgtgacagttgaaaaagaaattcccttgaaatgatcatgaggttaaaattttcttcattaggggacttggagaaccagtagtcgtaagattagttgatagtttcactcccaagcaatgaattgcttctgtgtgtttccctgtaggactcaatagtaaatgctgtctgtcttacacatttataaggaccctgcaagacgacgacaaaggcctttggcctgtgctactaaacaagaagcctatgaaaaatttcttctttaaacttgttttttctctttccagtaagttcacatttggataattttaaaaagaaaagtaattacctttgtgtttccagaacactataattggggtgtatcttaattcagttaaatattattagtagacctggattttcccccttgaccccatcagtctataaaggttaaactgcaacttttatgaaatggtctttaatatttccacaataatcctgtgctatatttgttttaagaaacaaagtaactctatacacttcaagactttacaggattttttaaatcctgtattgttggatcaattaataaagatgcaaaaaaactttatagagatgtaaaaacaaaactataatggatctcctatttttctttaaatacaaaaaaaaaaaggtaaatgaactattctccttgtaaagctaaattccccattctgtctaataaaggaagactgaaaaaaggttttaaagaacataaatggaaagatacaaatgctttgaaggaataaacgaaatgttaaaacagggtcaatccatttgaagaaaaagttggacaaaataatcagcattgctccctcttttatttaatatttgggtactgattatatccacatggaagtagaaggtaaggagtttaggaaaatactagaatctactctgcttacattcttgtttaagtgtttacacagtttggttcaattataaacatttggccttttactatgttatttttattttgtatgaatacattatcctccttatttatttttgttacatttattacttatgttattttgttatgcatttacaactccatttttaaataaagtgtttctggaactttaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:9859 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:9859 -> Cellular component: GO:0005813 [centrosome] evidence: IDA
            GeneID:9859 -> Cellular component: GO:0005814 [centriole] evidence: IEA
            GeneID:9859 -> Cellular component: GO:0005819 [spindle] evidence: IEA
            GeneID:9859 -> Cellular component: GO:0005874 [microtubule] evidence: IEA

by @meso_cacase at DBCLS
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