GGRNA Home | Help | Advanced search

2020-10-24 06:04:52, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001037954            5963 bp    mRNA    linear   PRI 21-JUN-2013
DEFINITION  Homo sapiens DIX domain containing 1 (DIXDC1), transcript variant
            1, mRNA.
ACCESSION   NM_001037954
VERSION     NM_001037954.3  GI:513126886
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5963)
  AUTHORS   Liu,Y.T., Dan,Q.J., Wang,J., Feng,Y., Chen,L., Liang,J., Li,Q.,
            Lin,S.C., Wang,Z.X. and Wu,J.W.
  TITLE     Molecular basis of Wnt activation via the DIX domain protein Ccd1
  JOURNAL   J. Biol. Chem. 286 (10), 8597-8608 (2011)
   PUBMED   21189423
  REMARK    GeneRIF: a molecular mechanism for Ccd1-mediated Wnt activation in
            that Ccd1 converts latent polymeric Dvl to a biologically active
            oligomer(s).
REFERENCE   2  (bases 1 to 5963)
  AUTHORS   Kivimae,S., Martin,P.M., Kapfhamer,D., Ruan,Y., Heberlein,U.,
            Rubenstein,J.L. and Cheyette,B.N.
  TITLE     Abnormal behavior in mice mutant for the Disc1 binding partner,
            Dixdc1
  JOURNAL   Transl Psychiatry 1, E43 (2011)
   PUBMED   22832659
  REMARK    GeneRIF: Transgenic DIXDC1 might contribute to pathophysiology
            underlying abnormal behaviors in schizophrenia and other major
            psychiatric disorders in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5963)
  AUTHORS   Singh,K.K., Ge,X., Mao,Y., Drane,L., Meletis,K., Samuels,B.A. and
            Tsai,L.H.
  TITLE     Dixdc1 is a critical regulator of DISC1 and embryonic cortical
            development
  JOURNAL   Neuron 67 (1), 33-48 (2010)
   PUBMED   20624590
  REMARK    GeneRIF: This study reveal that Dixdc1 integrates DISC1 into
            Wnt-GSK3beta/beta-catenin-dependent and -independent signaling
            pathways during cortical development and further delineate how
            DISC1 contributes to neuropsychiatric disorders.
REFERENCE   4  (bases 1 to 5963)
  AUTHORS   Wang,L., Li,H., Chen,Q., Zhu,T., Zhu,H. and Zheng,L.
  TITLE     Wnt signaling stabilizes the DIXDC1 protein through decreased
            ubiquitin-dependent degradation
  JOURNAL   Cancer Sci. 101 (3), 700-706 (2010)
   PUBMED   20085589
  REMARK    GeneRIF: Wnt/beta-catenin pathway activation might upregulate
            DIXDC1 through a post-translational mechanism by inhibiting the
            ubiquitin-mediated degradation of the DIXDC1 protein.
REFERENCE   5  (bases 1 to 5963)
  AUTHORS   Liu,T., Wang,L., Chen,Q., Zheng,L. and Zhu,H.
  TITLE     A novel monoclonal antibody specific to DIXDC1 protein
  JOURNAL   Hybridoma (Larchmt) 28 (3), 183-188 (2009)
   PUBMED   19519246
REFERENCE   6  (bases 1 to 5963)
  AUTHORS   Wu,Y., Jing,X., Ma,X., Wu,Y., Ding,X., Fan,W. and Fan,M.
  TITLE     DIXDC1 co-localizes and interacts with gamma-tubulin in HEK293
            cells
  JOURNAL   Cell Biol. Int. 33 (6), 697-701 (2009)
   PUBMED   19375513
  REMARK    GeneRIF: The GFP-tag fused DIXDC1 exogenously expressed co-localize
            with gamma-tubulin both at interphase and mitotic phase in the
            centrosomes.
REFERENCE   7  (bases 1 to 5963)
  AUTHORS   Jing,X.T., Wu,H.T., Wu,Y., Ma,X., Liu,S.H., Wu,Y.R., Ding,X.F.,
            Peng,X.Z., Qiang,B.Q., Yuan,J.G., Fan,W.H. and Fan,M.
  TITLE     DIXDC1 promotes retinoic acid-induced neuronal differentiation and
            inhibits gliogenesis in P19 cells
  JOURNAL   Cell. Mol. Neurobiol. 29 (1), 55-67 (2009)
   PUBMED   18629627
  REMARK    GeneRIF: DIXDC1 might play an important role during neurogenesis,
            overexpression of DIXDC1 in embryonic carcinoma P19 cells promoted
            neuronal differentiation, and inhibited gliogenesis induced by
            retinoic acid.
REFERENCE   8  (bases 1 to 5963)
  AUTHORS   Wang,X., Zheng,L., Zeng,Z., Zhou,G., Chien,J., Qian,C.,
            Vasmatzis,G., Shridhar,V., Chen,L. and Liu,W.
  TITLE     DIXDC1 isoform, l-DIXDC1, is a novel filamentous actin-binding
            protein
  JOURNAL   Biochem. Biophys. Res. Commun. 347 (1), 22-30 (2006)
   PUBMED   16814745
  REMARK    GeneRIF: Thus, our data provide the first evidence that l-DIXDC1
            may act as a novel branching component in the Wnt signaling pathway
            targeting both beta-catenin-TCF complex for gene expression and
            cytoskeleton for regulating dynamics of actin filaments.
REFERENCE   9  (bases 1 to 5963)
  AUTHORS   Wong,C.K., Luo,W., Deng,Y., Zou,H., Ye,Z. and Lin,S.C.
  TITLE     The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal
            kinase activation by Axin and dishevelled through distinct
            mechanisms
  JOURNAL   J. Biol. Chem. 279 (38), 39366-39373 (2004)
   PUBMED   15262978
  REMARK    GeneRIF: Ccd1 inhibits Axin-mediated JNK activation by
            simultaneously adopting two distinct mechanisms, one through
            conformational changes that disallow MEKK1 binding and the other
            via direct sequestration of MEKK4.
REFERENCE   10 (bases 1 to 5963)
  AUTHORS   Katoh,M. and Katoh,M.
  TITLE     KIAA1735 gene on human chromosome 11q23.1 encodes a novel protein
            with myosine-tail homologous domain and C-terminal DIX domain
  JOURNAL   Int. J. Oncol. 23 (1), 145-150 (2003)
   PUBMED   12792787
  REMARK    GeneRIF: KIAA1735 maps to human chromosome 11q23.1 and encodes a
            novel protein with a myosine-tail homologous domain and C-terminal
            DIX domain
            GeneRIF: MTHDIX (KIAA1735) protein consists of Myosine-tail
            homologous (MTH) domain and C-terminal DIX domain.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DQ642016.1, BC064479.1,
            AB051522.1, AB074187.1 and DB358954.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Jun 19, 2013 this sequence version replaced gi:116256345.
            
            Summary: The protein encoded by this gene is a positive regulator
            of the Wnt signaling pathway. The encoded protein is found
            associated with gamma tubulin at the centrosome. Alternative
            splicing results in multiple transcript variants encoding different
            isoforms. [provided by RefSeq, Jun 2013].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a, also known as
            l-DIXDC1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ642016.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025082, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-184               DQ642016.1         1-184
            185-1176            BC064479.1         1-992
            1177-2159           DQ642016.1         1177-2159
            2160-5292           AB051522.1         1600-4732
            5293-5897           AB074187.1         1108-1712
            5898-5963           DB358954.1         1-66                c
FEATURES             Location/Qualifiers
     source          1..5963
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q23.1"
     gene            1..5963
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /note="DIX domain containing 1"
                     /db_xref="GeneID:85458"
                     /db_xref="HGNC:23695"
                     /db_xref="MIM:610493"
     exon            1..357
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    205..207
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /note="upstream in-frame stop codon"
     CDS             298..2349
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /note="isoform a is encoded by transcript variant 1;
                     dixin; coiled-coil protein DIX1"
                     /codon_start=1
                     /product="dixin isoform a"
                     /protein_id="NP_001033043.1"
                     /db_xref="GI:83816971"
                     /db_xref="GeneID:85458"
                     /db_xref="HGNC:23695"
                     /db_xref="MIM:610493"
                     /translation="
MLACLTRGNLLDVLQEGFNEQQLQAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPGNQQEMKNNVEKVLQFVASKKIRMHQTSAKDIVDGNLKSIMRLVLALAAHFKPGSSRTVNQGRDSRAPLQSHRPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
"
     misc_feature    361..675
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /note="Calponin homology domain; actin-binding domain
                     which may be present as a single copy or in tandem repeats
                     (which increases binding affinity). The CH domain is found
                     in cytoskeletal and signal transduction proteins,
                     including actin-binding proteins like...; Region: CH;
                     cd00014"
                     /db_xref="CDD:28898"
     misc_feature    order(361..363,367..375,382..384,391..393,562..567,
                     574..576,583..585,589..591,634..639,646..651,655..660,
                     667..672)
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /note="putative actin binding surface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:28898"
     misc_feature    676..1197
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q155Q3.2);
                     Region: Actin-binding"
     misc_feature    2098..2337
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /note="DIX domain; Region: DIX; pfam00778"
                     /db_xref="CDD:189714"
     exon            358..487
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            488..613
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            614..845
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            846..953
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            954..1066
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1067..1215
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1216..1305
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1306..1359
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1360..1410
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1411..1515
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1516..1569
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1570..1662
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1663..1734
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1735..1824
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1825..1986
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            1987..2053
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            2054..2159
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            2160..2268
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     exon            2269..5963
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /inference="alignment:Splign:1.39.8"
     STS             3889..4136
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /standard_name="STS-AA026898"
                     /db_xref="UniSTS:6593"
     STS             4187..4339
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /standard_name="RH103217"
                     /db_xref="UniSTS:97550"
     STS             4472..5340
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /standard_name="DIXDC1__4742"
                     /db_xref="UniSTS:462869"
     STS             5142..5219
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /standard_name="RH36905"
                     /db_xref="UniSTS:87932"
     STS             5695..5846
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /standard_name="RH104183"
                     /db_xref="UniSTS:98508"
     polyA_signal    5873..5878
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
     polyA_site      5896
                     /gene="DIXDC1"
                     /gene_synonym="CCD1"
                     /note="The 3' most polyA site has not been determined."
ORIGIN      
tcccgcaggaaagcggggctgggggcagcccggcagcgccgctcaacctagtgcgcgcccagttgtttccataggaaccgcgaccgcgccgggcccctccagcggaggcccccgtgcgagcatgcccagtgcaagccgctagtttggctccagtctaggtttccagtaagtggcatgcgggactccggagggatcccaatgagctgagccgagagcctttgtgtgcagagggaggaggaggaggcggcggcggccgccgggctggagaccccgcccggggagcccccagcaggaacaatgctagcctgcctgacccgagggaacttactggacgtcctgcaggagggcttcaatgagcaacagctgcaggcctatgtggcctgggtgaatgcacagctgaagaagaggccagcagtgaagcctgtgcaggacctgcgacaagatctccgggatggggtgatcctggcatatctcatcgagattgttgcaggagaaaagctgagtggggtacagctgagtcccggtaaccaacaggagatgaagaataatgtggagaaagtgctacagtttgtggcctctaaaaagattcgtatgcaccagacttcggctaaagatattgtggatggaaacctgaagtctatcatgaggctggtccttgccttggcagctcatttcaaacctggctccagcaggacggtgaaccaaggacgggactccagagcccctctgcaaagtcaccgaccacactgtgccactgctgttgcccagggagcagctgctgctctggccgatgtgtgtcatgacatgtcccgatcaggacgggatgtctttcgatatagacagaggaacagcagcatggatgaggaaattgagaatccatactggagtgtgcgggccctagtgcagcagtacgaagggcaacaaaggtccccgtctgaatccagctgctccagcctgacttcacccagtccaatccacagtgcaaagagcgagtccattataacccagtcagaagagaaggcagattttgtgattattcccgctgaaggaatagagaacagaacagaagggacagattctccattatctcgagactggcggccagggagccctggaacctatctggagacctcatgggaagaacagctgttggaacaacaagaatatttagaaaaagaaatggaggaagcaaagaaaatgatatcaggactacaggccttactgctcaatggatccttacctgaagatgaacaggagaggcccttggccctctgtgaaccaggtgtcaatcccgaggaacaactgattataatccaaagtcgtctggatcagagtatggaggagaatcaggacttaaagaaggaactgctgaaatgtaaacaagaagccagaaacttacaggggataaaggatgccttgcagcagagattgactcagcaggacacatctgttcttcagctcaaacaagagctactgagggcaaatatggacaaagatgagctgcacaaccagaatgtggatctgcagaggaagctagatgagaggaaccggctcttgggagaatataaaaaagagctggggcagaaggatcgccttcttcagcagcaccaggccaagttagaagaagcactccggaaactctctgatgtcagttaccaccaggtggatctagagcgagagctagaacacaaagatgtcctcttggctcactgtatgaaaagagaggcagatgaggcgaccaactacaacagtcacaactctcaaagcaatggttttctccttccaacggcaggaaaaggagctacttcagtcagcaacagagggaccagcgacctgcagcttgttcgagatgctctccgcagcctgcgcaacagcttcagtggccacgatcctcagcaccacactattgacagcttggagcagggcatttctagcctcatggagcgcctgcatgttatggagacgcagaagaaacaagaaagaaaggttcgggtcaagtcacccagaactcaagtaggtagtgaataccgggagtcctggccccctaactcaaagttgcctcactcacagagctctccaactgtcagcagcacctgtactaaagtgctctatttcactgaccggtcacttacgcccttcatggtcaatataccaaagaggttggaggaggtgacgttaaaggattttaaagcagctattgatcgggaaggaaatcaccggtatcacttcaaagcactggatcctgagtttggcactgtcaaagaggagattttccatgatgatgatgccatccctggatgggaagggaaaattgtagcttgggtggaagaagaccatggagagaattaatgccaagtatcagattgagggcttatggaacctggtcactccctggctgcttcactcaggaaagggaactaaaaccagaatacactaagaagtttctagtttgtgtgccaaaacagaagcttctccaagcatgatggccacaggtcagtcctctttctgtgcctggcatatctggtacttaaaattctgtccaaatgtagaccatgggttcatctggagttccttgtccgtgggaacacagtgttctattctactctgaggacaacaaaccgaaggccttaaacgatggggatggatgatcccgcctctgtaggggcatggctgctattatctggaaattaggaattggatgcatcattcctgtgtgttacagtattattttaattggcctcaatggttgcagcaatcagagtcccagcgtttgtactcacagacaaggcaaaggtaccagcttttctgtttctttgaacctactgcaaaccaagaataactcatgaggtggtaccaaagatgaaagcccagacttcagtaatcttttgaaccagacgtggatggtgctgaattgttgcttggatggaaaaagggctgcccatgttgtgctacactatgctaaaactgtaatttagtaagaccttgggctgcctcttctgtcttaactggttctgcagcttgtccttttgcccacatagggcctatttcatgtactgttagttttctctggggactctttaactttagagccatttctttttcttcaaactgatgaacttttgtttgaaaggcataaggagtgaaaagctccttgaaaatccaggcgggtatggaaaggtgctgctacccatatctttttgactttctttgtttcatgactttaactcatggcatctcctttgtagtaaaaggagacagaccattaatttcagcatttctttgtgatttataagtactgagcatgaagtacttgtctgcccctcatttcaaggccagagttattttctatttatgtattagtctaggctgatcttttagggcacaatagaaaccatggggcgtggagcatgagttgtgaatggcagggatcattctgggtaaaaaaaacctagaatcatttctgatgtgcaacattgtcaagtgaagaagctaacagttcaactaccgagattatttgataacctgggttttctcattcatccatcaagcaccatcaaccagtcagccattattatttatatatgtattaccaaaagcagtctatctgcctgtgacctccaatgtacactgccaaacacaagagtaggacacatctgttctgggttcttgacctatctgtctccaattcatctccccttttcagccatttcaacaaactactctttggagctctgagatgacatcttgttgttttatatagatgtatcttttaaaaatagttcacgtttggagaattcttttgtactcatttgctttttgtctgagaaccatgtctatttttataactggagtgtgagttctgtatcttctcacattctgtatactgtatccattttctagagaacccagtagcttttatacagtctcttcttaccaccccttgtggtttcagaacaagctttattttattacgagtatattaatgacaactaattcctgttccaattctacctgttttagttgtgaaggtagttttgtgtaatccagttgattgctcctctggcagagagaaggagctcaaaagatacttgatgtctttcatgtaagtttacctggtcttttcctattgaagaatttttcatcagaaacgactgggaaagtttgggaaagtcagcaaaagaaagaatgcatttcgaaagcaaacagaagaaaaaagtatattctcacagtttttccccaggaagtctggagaaaaagtcctcatgtcaccaatttctctgttgcatgaattttagtgttttgctataagacagcatgagggctatcaggccaaaattcattattgtatttccaatacagtttgtcttgaatgtctgtctcttaaaccagtttttacttgtcagttttctctcagcaaacagtcttactattatgtggaatttaacttttcagagaaaatttccaaagtcctctaccttatttggcttttatctgtgtcttttggaaaaggagctgcatggcctcagtgcctccataaaaagcttaagttgagttcatgggagaacattaagatcgttttttttcccttttagctcggtaatctcatgtaccacaggtaatgaccaagcatctctgctagaggatgtaactctcataactcctgtgtaaaatgaggatcctgttggtgatcctcattccagtttccaaagcgagaggagccttctgagcagaagtatgcaagactgattctgtttggaacagtttcctatttggctgcattctaggaggcctcctgacttattcatagtattgtcgcctggtggcattggtgtggggtagcttgtcctgctacttgctaaagttctctttctttgagaaaactgaggaaccagaatgcttagagttcataaaataatctctaaaccatgttaggttaaaacaaaatgaccatctcacaaaaacgagtttagttgaatgctcaattccttacaaaatcttcatttaaggctgagtgtggtggctcatgcctgtaattccagcactttgggaggccgaggcaggaagactgcttgagcccaggagttcaagaccagcctgggcaacgtaggaagactccgtctctacatagaaattttattataaaagtagctggggatggtggcacacacctgtagtcccagctactcaggaggttgaggtgggaagattgcttgagcccaggagtttgaggttgcagtgagctgatcatgccactgcactctagcctaggctacagagcaggaccccatctccaaaaaaaaaaaaaaaaaagtcatttaaaaactgaagaatgttctcttcttgctcagttccctaaattagctggggggattgggatactttacaatttttacatttttaaatttgaagaatttgttttaaacttacttggtaatggcacttctacttactgaccaacttttcagctctttttgaccaggatggttgcaaattagggaaaatatctttatactatacatccaattcaagaggactttaattacttaaaagcatttaggtcataattaaaattattttcactgtttccataaaataagcattatgattgcacactccttctactgtctgaatttatgtaagaggtatagcttgcttaaaatacatatatatgtaaagttatattttcttagaaacatggatgtttacagccattgctttcaaagagattattactgtgtattctccctgttttacaatatgttttcatgaagactatgttacaccagaggcttctgattatcaaagtgataaccagttttaactgccggtatgtaccagatttgtgaactaatttaaaaaaccacaaactatgaataaaatggggtttgcaaactaaatatcattaatgattttcacttgcgtttactgatgagattaatcaataaagccatttacatttagtg
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:85458 -> Molecular function: GO:0003779 [actin binding] evidence: IEA
            GeneID:85458 -> Molecular function: GO:0004871 [signal transducer activity] evidence: IEA
            GeneID:85458 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:85458 -> Molecular function: GO:0031435 [mitogen-activated protein kinase kinase kinase binding] evidence: IBA
            GeneID:85458 -> Molecular function: GO:0043015 [gamma-tubulin binding] evidence: IDA
            GeneID:85458 -> Biological process: GO:0021695 [cerebellar cortex development] evidence: IBA
            GeneID:85458 -> Biological process: GO:0030900 [forebrain development] evidence: IBA
            GeneID:85458 -> Biological process: GO:0043010 [camera-type eye development] evidence: IBA
            GeneID:85458 -> Biological process: GO:0046328 [regulation of JNK cascade] evidence: IBA
            GeneID:85458 -> Biological process: GO:0050772 [positive regulation of axonogenesis] evidence: IBA
            GeneID:85458 -> Biological process: GO:0060071 [Wnt receptor signaling pathway, planar cell polarity pathway] evidence: IRD
            GeneID:85458 -> Biological process: GO:0090263 [positive regulation of canonical Wnt receptor signaling pathway] evidence: IDA
            GeneID:85458 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
            GeneID:85458 -> Cellular component: GO:0005925 [focal adhesion] evidence: IEA
            GeneID:85458 -> Cellular component: GO:0005938 [cell cortex] evidence: IBA
            GeneID:85458 -> Cellular component: GO:0043025 [neuronal cell body] evidence: IBA
            GeneID:85458 -> Cellular component: GO:0043679 [axon terminus] evidence: IBA

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.