LOCUS       NM_001012991            1974 bp    mRNA    linear   PRI 09-JUN-2013
DEFINITION  Homo sapiens lysine-rich nucleolar protein 1 (KNOP1), mRNA.
ACCESSION   NM_001012991 XM_001126237 XM_001132285
VERSION     NM_001012991.2  GI:111607440
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1974)
  AUTHORS   Loftus,B.J., Kim,U.J., Sneddon,V.P., Kalush,F., Brandon,R.,
            Fuhrmann,J., Mason,T., Crosby,M.L., Barnstead,M., Cronin,L.,
            Deslattes Mays,A., Cao,Y., Xu,R.X., Kang,H.L., Mitchell,S.,
            Eichler,E.E., Harris,P.C., Venter,J.C. and Adams,M.D.
  TITLE     Genome duplications and other features in 12 Mb of DNA sequence
            from human chromosome 16p and 16q
  JOURNAL   Genomics 60 (3), 295-308 (1999)
   PUBMED   10493829
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC117562.1.
            On or before Sep 20, 2006 this sequence version replaced
            gi:113426006, gi:113426340, gi:61175269.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC117562.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1974
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p12.3"
     gene            1..1974
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /note="lysine-rich nucleolar protein 1"
                     /db_xref="GeneID:400506"
                     /db_xref="HGNC:34404"
     exon            1..13
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /inference="alignment:Splign:1.39.8"
     exon            14..933
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /inference="alignment:Splign:1.39.8"
     CDS             16..1392
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /note="family with sequence similarity 191, member A;
                     protein C16orf88; testis-specific gene 118 protein"
                     /codon_start=1
                     /product="lysine-rich nucleolar protein 1"
                     /protein_id="NP_001013009.2"
                     /db_xref="GI:111607441"
                     /db_xref="CCDS:CCDS42127.1"
                     /db_xref="GeneID:400506"
                     /db_xref="HGNC:34404"
                     /translation="

MITKTHKVDLGLPEKKKKKKVVKEPETRYSVLNNDDYFADVSPLRATSPSKSVAHGQAPEMPLVKKKKKKKKGVSTLCEEHVEPETTLPARRTEKSPSLRKQVFGHLEFLSGEKKNKKSPLAMSHASGVKTSPDPRQGEEETRVGKKLKKHKKEKKGAQDPTAFSVQDPWFCEAREARDVGDTCSVGKKDEEQAALGQKRKRKSPREHNGKVKKKKKIHQEGDALPGHSKPSRSMESSPRKGSKKKPVKVEAPEYIPISDDPKASAKKKMKSKKKVEQPVIEEPALKRKKKKKRKESGVAGDPWKEETDTDLEVVLEKKGNMDEAHIDQVRRKALQEEIDRESGKTEASETRKWTGTQFGQWDTAGFENEDQKLKFLRLMGGFKNLSPSFSRPASTIARPNMALGKKAADSLQQNLQRDYDRAMSWKYSRGAGLGFSTAPNKIFYIDRNASKSVKLED

"
     misc_feature    139..141
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q1ED39.1); phosphorylation site"
     misc_feature    154..156
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    163..165
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q1ED39.1); phosphorylation site"
     misc_feature    163..165
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    346..348
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q1ED39.1); phosphorylation site"
     misc_feature    808..810
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q1ED39.1); phosphorylation site"
     misc_feature    931..1389
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q1ED39.1);
                     Region: Interaction with ZNF106 (By similarity)"
     misc_feature    937..939
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (Q1ED39.1); phosphorylation site"
     misc_feature    943..945
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (Q1ED39.1); phosphorylation site"
     STS             22..240
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /standard_name="D8S1410E"
                     /db_xref="UniSTS:151203"
     STS             724..870
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /standard_name="RH48839"
                     /db_xref="UniSTS:14050"
     variation       812
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2074036"
     exon            934..1002
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /inference="alignment:Splign:1.39.8"
     exon            1003..1080
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /inference="alignment:Splign:1.39.8"
     exon            1081..1950
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /inference="alignment:Splign:1.39.8"
     variation       1455
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:56590213"
     STS             1594..1727
                     /gene="KNOP1"
                     /gene_synonym="101F10.1; C16orf88; FAM191A; TSG118"
                     /standard_name="RH69601"
                     /db_xref="UniSTS:88603"
ORIGIN      

atttcgcccaccggaatgatcaccaagacacacaaagtagaccttgggctcccagagaagaaaaagaagaagaaagtggtcaaagaaccagagactcgatactcagttttaaacaatgatgattactttgctgatgtttctcctttaagagctacatccccctctaagagtgtggcccatgggcaggcacctgagatgcctctagtgaagaaaaagaagaagaaaaagaagggtgtcagcaccctttgcgaggagcatgtagaacctgagaccacgctgcctgctagacggacagagaagtcacccagcctcaggaagcaggtgtttggccacttggagttcctcagtggggaaaagaaaaataagaagtcacctctagccatgtcccatgcctctggggtgaaaacctccccagaccctagacagggtgaggaggaaaccagagttggcaagaagctcaaaaaacacaagaaggaaaaaaagggggcccaggaccccacagccttctcggtccaggacccttggttctgtgaggccagggaggccagggatgttggggacacttgctcagtggggaagaaggatgaggaacaggcagccttggggcagaaacggaagcggaagagccccagagaacacaatgggaaggtgaagaagaaaaaaaaaatccaccaggagggagatgccctcccaggccactccaagccctccaggtccatggagagcagccctaggaaaggaagtaaaaagaagccagtcaaagttgaggctccggaatacatccccataagtgatgaccctaaggcctccgcaaagaaaaagatgaagtccaaaaagaaggtagagcagccagtcatcgaggagccagctctgaaaaggaagaaaaagaagaagaggaaagagagtggggtagcaggagacccttggaaggaggaaacagacacggacttagaggtggtgttggaaaaaaaaggcaacatggatgaggcgcacatagaccaggtgaggcgaaaggccttgcaagaagagatcgatcgcgagtcaggcaaaacggaagcttctgaaaccaggaagtggacgggaacccagtttggccagtgggatactgctggttttgagaacgaggaccaaaaactgaaatttctcagacttatgggtggcttcaaaaacctgtccccttcgttcagccgccccgccagcacgattgcaaggcccaacatggccctcggcaagaaggcggctgacagcctgcagcagaatctgcagcgggactacgaccgggccatgagctggaagtacagccggggagccggcctcggcttctccaccgcccccaacaagatcttttacattgacaggaacgcttccaagtcagtcaagctggaagattaaactctagagttttgtccccccaaaactgccacaattgctttgattattccatttatgctggagattacaaattttttttgtgaaaaaatcagatcttggtgaggacctcgagcagtaagatataaataactcccataagcttagcgttccagtaatggaacactaggcataaatggtttattcagttgtgcaaatgaaagccatctgacagttggctcacattgaacacctgtggagattaaggacgaggacaactatattgatgggcttggatgaactggggcagggcagctcatatttcgggagccaggagaacgagtgagtgctaaaacctcctgttttctgtgttaaacattccgtccctgtttgagacatcagtatgtacagttaacttttgttgagtgtttagcaggtactagggacatactagtgttttccttaatgtatttaatcttcataattatgaaatgggtgctattattagccccatcttatagatgaggcaactgaggttcagggataaagtaataaaattgcctggggtcacccagccactaaaaaaaaaaaaaaaaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:400506 -> Cellular component: GO:0005730 [nucleolus] evidence: IEA