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2024-04-19 08:47:52, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001008224 7096 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens uveal autoantigen with coiled-coil domains and ankyrin
repeats (UACA), transcript variant 2, mRNA.
ACCESSION NM_001008224
VERSION NM_001008224.1 GI:56550046
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7096)
AUTHORS Moravcikova,E., Krepela,E., Prochazka,J., Rousalova,I., Cermak,J.
and Benkova,K.
TITLE Down-regulated expression of apoptosis-associated genes APIP and
UACA in non-small cell lung carcinoma
JOURNAL Int. J. Oncol. 40 (6), 2111-2121 (2012)
PUBMED 22407486
REMARK GeneRIF: The down-regulation of APIP and UACA expression suggests
that the threshold to activate the apoptosome apparatus may be
decreased in non-small cell lung cancer cells.
REFERENCE 2 (bases 1 to 7096)
AUTHORS Trynka,G., Zhernakova,A., Romanos,J., Franke,L., Hunt,K.A.,
Turner,G., Bruinenberg,M., Heap,G.A., Platteel,M., Ryan,A.W., de
Kovel,C., Holmes,G.K., Howdle,P.D., Walters,J.R., Sanders,D.S.,
Mulder,C.J., Mearin,M.L., Verbeek,W.H., Trimble,V., Stevens,F.M.,
Kelleher,D., Barisani,D., Bardella,M.T., McManus,R., van Heel,D.A.
and Wijmenga,C.
TITLE Coeliac disease-associated risk variants in TNFAIP3 and REL
implicate altered NF-kappaB signalling
JOURNAL Gut 58 (8), 1078-1083 (2009)
PUBMED 19240061
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 3 (bases 1 to 7096)
AUTHORS Cockman,M.E., Lancaster,D.E., Stolze,I.P., Hewitson,K.S.,
McDonough,M.A., Coleman,M.L., Coles,C.H., Yu,X., Hay,R.T.,
Ley,S.C., Pugh,C.W., Oldham,N.J., Masson,N., Schofield,C.J. and
Ratcliffe,P.J.
TITLE Posttranslational hydroxylation of ankyrin repeats in IkappaB
proteins by the hypoxia-inducible factor (HIF) asparaginyl
hydroxylase, factor inhibiting HIF (FIH)
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 103 (40), 14767-14772 (2006)
PUBMED 17003112
REFERENCE 4 (bases 1 to 7096)
AUTHORS Ohkura,T., Taniguchi,S., Yamada,K., Nishio,N., Okamura,T.,
Yoshida,A., Kamijou,K., Fukata,S., Kuma,K., Inoue,Y., Hisatome,I.,
Senju,S., Nishimura,Y. and Shigemasa,C.
TITLE Detection of the novel autoantibody (anti-UACA antibody) in
patients with Graves' disease
JOURNAL Biochem. Biophys. Res. Commun. 321 (2), 432-440 (2004)
PUBMED 15358194
REMARK GeneRIF: UACA is a novel candidate for eye muscle autoantigens in
thyroid-associated ophthalmopathy
REFERENCE 5 (bases 1 to 7096)
AUTHORS Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
TITLE Large-scale characterization of HeLa cell nuclear phosphoproteins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
PUBMED 15302935
REFERENCE 6 (bases 1 to 7096)
AUTHORS Yamada,K., Senju,S., Nakatsura,T., Murata,Y., Ishihara,M.,
Nakamura,S., Ohno,S., Negi,A. and Nishimura,Y.
TITLE Identification of a novel autoantigen UACA in patients with
panuveitis
JOURNAL Biochem. Biophys. Res. Commun. 280 (4), 1169-1176 (2001)
PUBMED 11162650
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AK055435.1, AF322916.1, BC016881.1, AB046781.2, BM693348.1,
AC087699.11 and BU736944.1.
Transcript Variant: This variant (2) has a longer and alternate 5'
exon, as compared to variant 1. The encoded isoform 2 has a shorter
and distinct N-terminus, as compared to isoform 1.
##Evidence-Data-START##
RNAseq introns :: single sample supports all introns ERS025098
[ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-479 AK055435.1 28-506
480-743 AF322916.1 202-465
744-2267 BC016881.1 733-2256
2268-3281 AB046781.2 1941-2954
3282-3557 BM693348.1 212-487
3558-4700 AB046781.2 3231-4373
4701-6517 AC087699.11 115182-116998 c
6518-7096 BU736944.1 1-579 c
FEATURES Location/Qualifiers
source 1..7096
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q22-q24"
gene 1..7096
/gene="UACA"
/gene_synonym="NUCLING"
/note="uveal autoantigen with coiled-coil domains and
ankyrin repeats"
/db_xref="GeneID:55075"
/db_xref="HGNC:15947"
/db_xref="MIM:612516"
exon 1..405
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
misc_feature 355..357
/gene="UACA"
/gene_synonym="NUCLING"
/note="upstream in-frame stop codon"
CDS 367..4578
/gene="UACA"
/gene_synonym="NUCLING"
/note="isoform 2 is encoded by transcript variant 2;
nuclear membrane binding protein; uveal autoantigen with
coiled coil domains and ankyrin repeats"
/codon_start=1
/product="uveal autoantigen with coiled-coil domains and
ankyrin repeats isoform 2"
/protein_id="NP_001008225.1"
/db_xref="GI:56550047"
/db_xref="CCDS:CCDS32280.1"
/db_xref="GeneID:55075"
/db_xref="HGNC:15947"
/db_xref="MIM:612516"
/translation="
MMNCWFSCTPKNRHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
"
misc_feature 439..786
/gene="UACA"
/gene_synonym="NUCLING"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 439..702
/gene="UACA"
/gene_synonym="NUCLING"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 619..987
/gene="UACA"
/gene_synonym="NUCLING"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 640..918
/gene="UACA"
/gene_synonym="NUCLING"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 838..1083
/gene="UACA"
/gene_synonym="NUCLING"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 907..>1110
/gene="UACA"
/gene_synonym="NUCLING"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 2047..4482
/gene="UACA"
/gene_synonym="NUCLING"
/note="Chromosome segregation ATPases [Cell division and
chromosome partitioning]; Region: Smc; COG1196"
/db_xref="CDD:31389"
misc_feature 2494..2496
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2728..2730
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3520..3522
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/citation=[5]
exon 406..539
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 540..628
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 629..693
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 694..751
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 752..822
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 823..929
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 930..1111
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1112..1149
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1150..1218
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1219..1326
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1327..1359
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1360..1458
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1459..1495
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1496..1548
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1549..4287
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
STS 3668..3834
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="SHGC-56623"
/db_xref="UniSTS:19628"
variation 3969
/gene="UACA"
/gene_synonym="NUCLING"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1056326"
exon 4288..4440
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 4441..4506
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 4507..7080
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
STS 4514..4661
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="D15S1354"
/db_xref="UniSTS:4637"
polyA_signal 4676..4681
/gene="UACA"
/gene_synonym="NUCLING"
polyA_signal 4681..4686
/gene="UACA"
/gene_synonym="NUCLING"
polyA_site 4701
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
polyA_signal 5151..5156
/gene="UACA"
/gene_synonym="NUCLING"
polyA_site 5170
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
variation 5855
/gene="UACA"
/gene_synonym="NUCLING"
/replace=""
/replace="c"
/db_xref="dbSNP:71152306"
STS 6133..6165
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="GDB:335751"
/db_xref="UniSTS:156601"
STS 6215..6303
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 6265..6334
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="D1S1423"
/db_xref="UniSTS:149619"
polyA_signal 6510..6515
/gene="UACA"
/gene_synonym="NUCLING"
polyA_site 6528
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
STS 6854..7007
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="RH98418"
/db_xref="UniSTS:91735"
variation 7000
/gene="UACA"
/gene_synonym="NUCLING"
/replace="c"
/replace="g"
/db_xref="dbSNP:720519"
polyA_signal 7054..7059
/gene="UACA"
/gene_synonym="NUCLING"
polyA_site 7080
/gene="UACA"
/gene_synonym="NUCLING"
ORIGIN
gtgttgaggcagcaggatgcagagtgctgttcaagttttccagtggggtccctcaaagggacaactttgaaagatagctagcttccaaagaataagaaatagatagagttactgtacctgacttggggctgctcttaatcaagttctgcattgcaaggaagataatattcgagcgttatgaaggcggagaaggatcctgaagacgaagaaaatatcgttagagatccaagctaagtgtagcacagcatgtgagggactgagtcacttgtcaggagtttgtctgagagtttgctttgtgagcttacagagatttgtaacttaatgcaaagtagtttgccattagcaacaagaaactaaatcctgtctatgatgaactgttggttttcttgtactcctaagaacagacatgcagcagattggaataaatatgatgaccgattgatgaaagcagcagaaaggggggatgtagaaaaagtgacctcaatccttgctaaaaagggggtcaatccaggcaaactagatgtggaaggcagatctgtcttccatgttgtgacctcaaaggggaatcttgagtgtttgaatgccatccttatacatggagttgatattacaaccagtgacactgcagggagaaatgctcttcacctggctgctaagtatggacatgcattgtgcctacaaaaacttctacagtacaattgtcccactgagcatgcagacctgcagggaagaactgcacttcacgatgccgcaatggcagattgtccttctagcatacagctgctttgtgaccatggggcctctgtgaatgccaaagatgtagacgggcggacaccacttgttctggctactcagatgagtaggccaacaatatgtcaactgctgatagatagaggagcggatgttaattccagagacaaacaaaacagaactgccctcatgctaggttgcgaatatggttgcagagatgcagtagaagtcttaattaaaaatggtgctgatataagcttgctggatgcgcttggccatgatagttcttactatgcaagaattggtgacaatctggacattctaaccttgttgaagactgcatcggaaaataccaacaaagggagagaactttggaagaaagggccatctttgcaacagcgaaatttgacacacatgcaagatgaagtaaatgtgaagtcacatcagagggagcatcaaaatattcaggatttggagattgaaaatgaagatttgaaagagaggttgagaaaaattcagcaagaacaaagaatacttttggataaagtcaatggtttacagttacagctgaatgaggaagttatggttgctgatgatctggaaagcgagagagaaaagctgaagtcccttttggcagctaaagaaaagcaacatgaagaaagcttaaggactattgaggctctgaaaaatagatttaaatattttgagagtgatcatttaggatcaggaagtcatttcagtaaccgaaaagaagatatgcttcttaaacaaggtcagatgtatatggcagactcacagtgtacttccccaggtataccagcccatatgcaaagcagatctatgttaagacctctggaactatctttacccagtcaaacgtcatactctgaaaatgaaattttaaagaaagagttagaagcaatgcgaactttctgtgagtcagcaaaacaagaccgactgaagctccaaaatgaactggcacacaaagtggcagaatgcaaagctttagcattagaatgtgaaagggtcaaggaggattcagatgaacagataaagcaattagaagatgcattaaaagatgtgcagaagaggatgtatgagtcagaaggtaaagttaaacaaatgcagacccattttcttgcccttaaagaacacttaacaagtgaagcagcctcagggaatcacagactaaccgaggaactgaaggatcagttgaaagacttgaaagtaaaatatgaaggtgcttcagcagaagtggggaaattaagaaaccaaatcaaacaaaatgagatgatagtagaagagtttaagagggatgaaggcaagctgatagaagaaaataagcgattacagaaggaacttagtatgtgtgaaatggagcgagagaagaaaggaagaaaggtcacagagatggaaggccaggcaaaagaattgtcagcgaagttggccctttccattccagctgaaaaatttgaaaacatgaagagctcattatcaaatgaagtgaatgagaaagcaaaaaaattagtagaaatggaaagagaacatgaaaaatcacttagtgaaattagacagttaaagagagaacttgagaatgttaaggccaagcttgctcagcacgtcaaaccagaggaacatgaacaggttaagagcagattagaacagaaatcaggagaacttgggaagaagatcactgagttaacattgaaaaatcagacactacaaaaggaaattgaaaaagtttatttggataataagctcctcaaggagcaagcacataacttaacaattgaaatgaaaaatcattatgttcctttaaaagtaagtgaagacatgaaaaagtcacatgatgcaattattgatgatcttaatagaaagcttttagatgtaacacaaaaatatacagaaaagaagttggaaatggagaaattgctactggaaaatgacagcttaagtaaggatgtaagccgcctagaaactgtgtttgtacctcctgagaaacatgaaaaagagataatagctctgaaatccaatattgttgaacttaagaaacagctgtctgaacttaagaaaaaatgtggtgaagaccaggagaaaatacacgctctcacatctgaaaacactaacttgaagaagatgatgagtaatcagtatgtgccagttaaaacccatgaagaggttaaaatgacactgaatgacacgttagccaaaactaacagagaattattagatgtgaagaaaaaatttgaagatataaatcaggaatttgtaaaaataaaagataagaatgaaatattaaaaagaaacctggaaaacactcagaaccaaataaaagctgagtacatcagcctggcagagcacgaggcaaagatgagctcgctaagtcagagcatgagaaaggtgcaggatagtaatgctgaaatcttggccaactacagaaaaggccaagaagagattgtgacactgcatgccgaaattaaagcccagaagaaggagctcgacacaatacaagaatgcattaaggtaaaatacgccccaattgtcagctttgaggagtgcgagagaaaatttaaagcaacagagaaagaactaaaagaccagttatcagagcagacacaaaagtatagtgtcagtgaagaagaagtcaagaaaaacaagcaagagaatgacaagttaaagaaggagatttttacccttcagaaagatttgagagataagacagttctcattgagaagtctcatgaaatggaaagagcattaagcagaaaaacagacgagctaaacaaacagttaaaagacttgtcacagaaatacacggaagtaaagaatgtgaaagagaagctagtagaagaaaatgccaaacagacttctgagatacttgcagtgcaaaatcttttgcaaaaacaacatgttccattggaacaggttgaggctctgaaaaaatctcttaatggcacaattgaaaatctaaaggaagaactgaagagtatgcaaaggtgttacgagaaagagcagcagacagtgaccaaactgcatcaattgttggagaatcaaaagaactcttctgtacccctggcagagcatttgcagattaaagaagcatttgagaaagaagttggaatcataaaagccagcttgagagaaaaggaagaagaaagccaaaacaaaatggaagaagtctccaaacttcagtcggaggttcagaatactaaacaagcattaaaaaaattagagactagagaggtagttgacttgtctaaatataaagcaacaaaaagtgatttggagacacagatttctagcttaaatgaaaaattggccaatctgaatagaaagtatgaggaagtatgtgaggaagttttgcatgccaaaaagaaggaaatatctgcaaaagatgagaaggaattactgcatttcagcattgagcaagaaattaaggatcagaaggaacgatgtgataagtccttaacaacaatcacagagttacaaagaagaatacaagaatctgctaaacaaatagaagcaaaagataataagataactgaactgcttaatgatgtggaaagattaaaacaggcactcaatggcctttcccaactcacctacacaagtgggaaccccaccaagaggcagagccagctgattgacactctgcagcaccaagtgaaatctctggagcaacagctggccgatgctgacagacagcaccaagaagtaattgcaatttatcggacacaccttcttagtgctgcacagggtcacatggatgaagatgttcaggaggctctgctccagatcatacaaatgcggcaggggcttgtgtgctagccgttagcactgactgccagtatctgttttatcttgctggtgctgaacattctttgtgcaactccatggtctttctgggccttactgtgctggtataattaaaataaaatatattttgttctattggtaggtttttttttaaaattagatgaatatgttagtctttttcaatatcagtttgaatcttattttctgtatgtgttaattttacaaataggcaaacaacataactttgccctggattgactacatatttttaaaccttcaagtccctaataaaacatgagccatctgagtgagtccatatgaagcgaggttaggctgaaataattgcttaaagatgtctttcagagaaattaatttggttggtggccacttttaggtggatcaaaagacctttcagatcctcagaaccttgagacataatacagttgtgaggaatgtgttgtaacttggctggccaagttacatgttacagtatctttactgaggtaacttcattagtgtctttggccttttttgtaggtatagatattttttctttttacactaataacttttatgccttttaaaataaatttattttcataaatggtttgcagtgctaaattacatttagattaagaacaggcaggggtggaatatatcaggaatttataataaaattgccttaatctctacaacagtatcttaatttttacttgcggtgactattcttgccacaatattggagaataatgatagatgatatactagatttttcaaagtgtgaaaacctttagactttttttagcaattagtttgacattcgctactatagtaaccaagcactcattatatatgcatcctccaaatgtttcatgcttatttataggaaagttatattaatgagattaataatgtgaaatacagttttcctgcaaaattagcattagagaattgattttagataacagatttttaaagttttagagaaaagtacagtaatacagtaaactgaaagagtatatagatagcaataaaataacataagtggacatgtttatagtaaatactctgaagtaaacaaccgtttttattaactgcatctcattagggaaagtttatatgtcttgttattttttattaacattttatttaccattcagagtgaaaattactaatttgagtattaacaaataactgaataaatggatcattacagttaggttttctcaaattgcaaaatttgccttagcaattatctttgaacatcccgaaccagatttttaaatcccatttttgtttaatagggtaaaaataccatcaaaatgacttctcataccaaagaataagccatcatattttttcggtgttgaaacaacattgaaagtcagaattggatttgtttttaattctttatacggtttacataagcaatatctgtctctttaattattatgattaatgtcgtccttcagcatgagttctgtttcacaagttttgggccacctatttcaataaaaaataaaatataaattaaaaaagttgccgggggtggtggctcatgcctgtaatcccagcactttgggaggctgagggaggtagatcacctgaggtcagaagttcgagaccagccttaccaatatggtgaagccccatctctactaaaaatacaaaaattagccctgcatggtggcaggtgcctgtagtcccaggtactcgggaggctgagacaggagaatcgcttgaacctgggaggcggaggttgcagtgagccaagatctcgccactgcactccagcttgggcaatagcaagactccatctcaaaataaaataaaataaaacttagagcaaagtttaaaactgagtattcatattaagtgttttattttccatattagagatgggaagggaaccttatgtgtattttattttgttttcaaccatcaataaagttttctctagaatattgttttgaacatccttgtaaaagatttgcgagttaaactattttatttactgtctgtgagagcattgggagtaggaaacgatggactccaaagtacaagggagaatacccattttcattcagctatctggagtaaaatatcaagtacttccttcaactaatcttgtctcattcactcaccttttgatatcgaaggcagaaattgcgtttacaacactgaagaccaaagctttttaattagtaaacaagcggaacatagataatggacaatgctggccactgccattctgtgttcagaaagactatgagacctgaacatatggccaagaggaaagaagagtgacgttgtctaagatgtaatgagtgctctctgagagaatcactcaattcctattggagtgcaatccttacttgagaactttattactcttgttctgtgtagttttttttttttgtcacttccccatcagaaaagcatattctttttgatagagggtcagtgttataaataattgtcttttgaaataaaatcaaatattcatgcattgaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:55075 -> Molecular function: GO:0003674 [molecular_function] evidence: ND
GeneID:55075 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:55075 -> Biological process: GO:0008150 [biological_process] evidence: ND
GeneID:55075 -> Biological process: GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] evidence: IEA
GeneID:55075 -> Biological process: GO:0008631 [intrinsic apoptotic signaling pathway in response to oxidative stress] evidence: IEA
GeneID:55075 -> Biological process: GO:0009411 [response to UV] evidence: IEA
GeneID:55075 -> Biological process: GO:0042307 [positive regulation of protein import into nucleus] evidence: IEA
GeneID:55075 -> Biological process: GO:0042347 [negative regulation of NF-kappaB import into nucleus] evidence: IEA
GeneID:55075 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IEA
GeneID:55075 -> Biological process: GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process] evidence: IEA
GeneID:55075 -> Biological process: GO:0050728 [negative regulation of inflammatory response] evidence: IEA
GeneID:55075 -> Cellular component: GO:0005576 [extracellular region] evidence: NAS
GeneID:55075 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:55075 -> Cellular component: GO:0005635 [nuclear envelope] evidence: IEA
GeneID:55075 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:55075 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
GeneID:55075 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA
GeneID:55075 -> Cellular component: GO:0016020 [membrane] evidence: IEA
GeneID:55075 -> Cellular component: GO:0043293 [apoptosome] evidence: IEA
GeneID:55075 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
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