2024-03-29 15:02:45, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001005333 2928 bp mRNA linear PRI 17-APR-2013 DEFINITION Homo sapiens melanoma antigen family D, 1 (MAGED1), transcript variant 1, mRNA. ACCESSION NM_001005333 VERSION NM_001005333.1 GI:52632380 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2928) AUTHORS Zeng,Z.L., Wu,W.J., Yang,J., Tang,Z.J., Chen,D.L., Qiu,M.Z., Luo,H.Y., Wang,Z.Q., Jin,Y., Wang,D.S. and Xu,R.H. TITLE Prognostic relevance of melanoma antigen D1 expression in colorectal carcinoma JOURNAL J Transl Med 10, 181 (2012) PUBMED 22935435 REMARK GeneRIF: Univariate and multivariate analyses indicated that MAGED1 expression was an independent prognostic factor in colorectal carcinoma Publication Status: Online-Only REFERENCE 2 (bases 1 to 2928) AUTHORS Reddy,E.M., Chettiar,S.T., Kaur,N., Ganeshkumar,R., Shepal,V., Shanbhag,N.C. and Shiras,A. TITLE Dlxin-1, a member of MAGE family, inhibits cell proliferation, invasion and tumorigenicity of glioma stem cells JOURNAL Cancer Gene Ther. 18 (3), 206-218 (2011) PUBMED 21109781 REMARK GeneRIF: we establish the roles for Dlxin-1, one as an anti-tumorigenic and anti-invasive protein in high-grade gliomas and the other as an inducer of differentiation of glioma stem cells. REFERENCE 3 (bases 1 to 2928) AUTHORS Xue,X.Y., Liu,Z.H., Jing,F.M., Li,Y.G., Liu,H.Z. and Gao,X.S. TITLE Relationship between NRAGE and the radioresistance of esophageal carcinoma cell line TE13R120 JOURNAL Chin J Cancer 29 (10), 900-906 (2010) PUBMED 20868560 REMARK GeneRIF: NRAGE may participate in the formation of radioresistance of TE13R120 cells by changing its subcellular localization, but its relationship with cell apoptosis has not been confirmed. REFERENCE 4 (bases 1 to 2928) AUTHORS Davila,S., Froeling,F.E., Tan,A., Bonnard,C., Boland,G.J., Snippe,H., Hibberd,M.L. and Seielstad,M. TITLE New genetic associations detected in a host response study to hepatitis B vaccine JOURNAL Genes Immun. 11 (3), 232-238 (2010) PUBMED 20237496 REMARK GeneRIF: Observational study of gene-disease association. (HuGE Navigator) REFERENCE 5 (bases 1 to 2928) AUTHORS Matluk,N., Rochira,J.A., Karaczyn,A., Adams,T. and Verdi,J.M. TITLE A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway JOURNAL BMC Biol. 8, 7 (2010) PUBMED 20100315 REMARK GeneRIF: Data report that NRAGE, via the same XIAP-Tak1-Tab1 complex, is required for the phosphorylation of IKK -alpha/beta and subsequent transcriptional activation of the p65 subunit of NF-kappaB. Publication Status: Online-Only REFERENCE 6 (bases 1 to 2928) AUTHORS Masuda,Y., Sasaki,A., Shibuya,H., Ueno,N., Ikeda,K. and Watanabe,K. TITLE Dlxin-1, a novel protein that binds Dlx5 and regulates its transcriptional function JOURNAL J. Biol. Chem. 276 (7), 5331-5338 (2001) PUBMED 11084035 REFERENCE 7 (bases 1 to 2928) AUTHORS Zhang,C.G., Xing,G.C., Wei,H.D., Yu,Y.T. and He,F.C. TITLE [A new melanoma antigen-encoding gene subfamily in human chromosome X] JOURNAL Yi Chuan Xue Bao 28 (3), 197-203 (2001) PUBMED 11280991 REFERENCE 8 (bases 1 to 2928) AUTHORS Kubu,C.J., Goldhawk,D.G., Barker,P.A. and Verdi,J.M. TITLE Identification of the translational initiation codon in human MAGED1 JOURNAL Genomics 70 (1), 150-152 (2000) PUBMED 11087672 REFERENCE 9 (bases 1 to 2928) AUTHORS Salehi,A.H., Roux,P.P., Kubu,C.J., Zeindler,C., Bhakar,A., Tannis,L.L., Verdi,J.M. and Barker,P.A. TITLE NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis JOURNAL Neuron 27 (2), 279-288 (2000) PUBMED 10985348 REFERENCE 10 (bases 1 to 2928) AUTHORS Pold,M., Zhou,J., Chen,G.L., Hall,J.M., Vescio,R.A. and Berenson,J.R. TITLE Identification of a new, unorthodox member of the MAGE gene family JOURNAL Genomics 59 (2), 161-167 (1999) PUBMED 10409427 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX422007.2, BC014070.2 and AF132205.1. Summary: This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014070.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-37 BX422007.2 1-37 38-2912 BC014070.2 1-2875 2913-2928 AF132205.1 1372-1387 FEATURES Location/Qualifiers source 1..2928 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="X" /map="Xp11.23" gene 1..2928 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /note="melanoma antigen family D, 1" /db_xref="GeneID:9500" /db_xref="HGNC:6813" /db_xref="HPRD:02202" /db_xref="MIM:300224" exon 1..154 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 66..67 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="g" /db_xref="dbSNP:11541163" misc_feature 146..148 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /note="upstream in-frame stop codon" exon 155..235 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" CDS 191..2695 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /note="isoform a is encoded by transcript variant 1; neurotrophin receptor-interacting MAGE homolog; melanoma-associated antigen D1; MAGE-D1 antigen; MAGE tumor antigen CCF" /codon_start=1 /product="melanoma-associated antigen D1 isoform a" /protein_id="NP_001005333.1" /db_xref="GI:52632381" /db_xref="CCDS:CCDS35279.1" /db_xref="GeneID:9500" /db_xref="HGNC:6813" /db_xref="HPRD:02202" /db_xref="MIM:300224" /translation="
MAQKMDCGAGLLGFQNPDACRAVCHPLPQPPASTLPLSAFPTLCDPPYSQLRDPPAVLSCYCTPLGASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
" misc_feature 632..634 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 632..634 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 1790..2299 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /note="MAGE family; Region: MAGE; pfam01454" /db_xref="CDD:201804" exon 236..403 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 279 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:372507787" variation 315 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:141749849" variation 351 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:369340329" variation 354 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:377536231" variation 359 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:145588024" variation 396 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:371038613" exon 404..1111 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 416 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:200403502" variation 530 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:370800331" variation 533 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:375273111" variation 572 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:201938318" variation 588 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:202085108" variation 633 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:151112988" variation 665 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:141080853" variation 702 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /replace="t" /db_xref="dbSNP:113823505" variation 703 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:200269066" variation 704 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="c" /db_xref="dbSNP:137856838" variation 802 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:144264968" variation 824 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:200672367" variation 833 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:373610127" variation 862 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:183944548" variation 1020 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="g" /db_xref="dbSNP:187608453" variation 1044 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:372248500" variation 1070 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="c" /db_xref="dbSNP:12689461" exon 1112..1780 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 1172 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:41307638" variation 1179 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="c" /db_xref="dbSNP:200760701" variation 1225 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:140810987" variation 1251 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:374985036" variation 1271 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:144665907" variation 1307 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="g" /db_xref="dbSNP:369211587" variation 1317 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:373153783" variation 1420 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:138624949" variation 1437 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:202231305" variation 1528 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:141719497" variation 1571 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="c" /db_xref="dbSNP:199911189" variation 1603 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:376126768" variation 1609 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="c" /db_xref="dbSNP:370215151" variation 1648 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:184387756" variation 1649 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:200856189" variation 1685 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:377687584" variation 1740 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:144566171" variation 1751 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:148038224" exon 1781..1844 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" exon 1845..1924 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 1900 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:367685368" exon 1925..2016 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 1963 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:141770812" variation 1990 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:150589159" exon 2017..2096 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 2047 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:371683752" variation 2084 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:375975220" exon 2097..2139 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" exon 2140..2202 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 2153 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="g" /db_xref="dbSNP:199703705" exon 2203..2317 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" exon 2318..2703 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 2350 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="t" /db_xref="dbSNP:201229700" variation 2356 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:140668837" variation 2383 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:144656819" variation 2410 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:368745871" variation 2411 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:147478214" variation 2417 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="c" /db_xref="dbSNP:3199687" variation 2584 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:200548781" variation 2601 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="c" /db_xref="dbSNP:150014410" variation 2621 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:145319637" variation 2653 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:149192593" variation 2665 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:142436276" variation 2694 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:145598419" exon 2704..2912 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /inference="alignment:Splign:1.39.8" variation 2718 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:58080956" variation 2731 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="c" /db_xref="dbSNP:193192478" variation 2745 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:376570677" variation 2763 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:1136500" variation 2777 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="c" /replace="t" /db_xref="dbSNP:1136504" variation 2792 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="a" /replace="g" /db_xref="dbSNP:11541165" variation 2858..2859 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" /replace="" /replace="g" /db_xref="dbSNP:35938097" polyA_signal 2887..2892 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" polyA_site 2912 /gene="MAGED1" /gene_synonym="DLXIN-1; NRAGE" ORIGIN
ggcgaagaggcggggtcgcccaagctgccgcgctggcattttctcctggacaaggagagagtgcggctgctgagagccgagcccagcaatcccgatcctctgagtcgtgaagaagggaggcagcgagggggttggggttggggcctgaggcaagcccccaggctccgctcttgccagagggacaggagccatggctcagaaaatggactgtggtgcgggcctcctcggcttccagaatcctgacgcttgtagagcagtctgtcaccccctcccccagcctcctgcctccaccctccctctttctgcattccccactctgtgcgaccccccttattctcaactccgcgatccgcctgccgtcctgagctgctactgcacgcctcttggagcgtccccggctcctgctgaggcctccgtagaagacagcgccttgcttatgcagaccttgatggaggccatccagatctcagaggctccacctactaaccaggccaccgcagctgctagtccccagagttcacagcccccaactgccaatgagatggctgacattcaggtttcagcagctgccgctaggcctaagtcagcctttaaagtccagaatgccaccacaaaaggcccaaatggtgtctatgatttctctcaggctcataatgccaaggatgtgcccaacacgcagcccaaggcagcctttaagtcccaaaatgctaccccaaagggtccaaatgctgcctatgatttttcccaggcagcaaccactggtgagttagctgctaacaagtctgagatggccttcaaggcccagaatgccactactaaagtgggcccaaatgccacctacaatttctctcagtctctcaatgccaatgacctggccaacagcaggcctaagacccctttcaaggcttggaatgataccactaaggccccaacagctgatacccagacccagaatgtaaatcaggccaaaatggccacttcccaggctgacatagagaccgacccaggtatctctgaacctgacggtgcaactgcacagacatcagcagatggttcccaggctcagaatctggagtcccggacaataattcggggcaagaggacccgcaagattaataacttgaatgttgaagagaacagcagtggggatcagaggcgggccccactggctgcagggacctggaggtctgcaccagttccagtgaccactcagaacccacctggcgcaccccccaatgtgctctggcagacgccattggcttggcagaacccctcaggctggcaaaaccagacagccaggcagaccccaccagcacgtcagagccctccagctaggcagaccccaccagcctggcagaacccagtcgcttggcagaacccagtgatttggccaaacccagtaatctggcagaacccagtgatctggccaaaccccattgtctggcccggccctgttgtctggccgaatccactggcctggcagaatccacctggatggcagactccacctggatggcagaccccaccgggctggcagggtcctccagactggcaaggtcctcctgactggccgctaccacccgactggccactgccacctgattggccacttcccactgactggccactaccacctgactggatccccgctgattggccaattccacctgactggcagaacctgcgcccctcgcctaacctgcgcccttctcccaactcgcgtgcctcacagaacccaggtgctgcacagccccgagatgtggcccttcttcaggaaagagcaaataagttggtcaagtacttgatgcttaaggactacacaaaggtgcccatcaagcgctcagaaatgctgagagatatcatccgtgaatacactgatgtttatccagaaatcattgaacgtgcatgctttgtcctagagaagaaatttgggattcaactgaaagaaattgacaaagaagaacacctgtatattctcatcagtacccccgagtccctggctggcatactgggaacgaccaaagacacacccaagctcggtctcctcttggtgattctgggtgtcatcttcatgaatggcaaccgtgccagtgaggctgtcctctgggaggcactacgcaagatgggactgcgtcctggggtgagacatcccctccttggagatctaaggaaacttctcacctatgagtttgtaaagcagaaatacctggactacagacgagtgcccaacagcaaccccccggagtatgagttcctctggggcctccgttcctaccatgagactagcaagatgaaagtgctgagattcattgcagaggttcagaaaagagaccctcgtgactggactgcacagttcatggaggctgcagatgaggccttggatgctctggatgctgctgcagctgaggccgaagcccgggctgaagcaagaacccgcatgggaattggagatgaggctgtgtctgggccctggagctgggatgacattgagtttgagctgctgacctgggatgaggaaggagattttggagatccctggtccagaattccatttaccttctgggccagataccaccagaatgcccgctccagattccctcagacctttgccggtcccattattggtcctggtggtacagccagtgccaacttcgctgccaactttggtgccattggtttcttctgggttgagtgagatgttggatattgctatcaatcgcagtagtctttcccctgtgtgaggctgaagcctcagattccttctaaacacagctatctagagagccacatcctgttgactgaaagtggcatgcaagataaatttatttgctgttccttgtctactgctttttttccccttgtgtgctgtcaagttttggtatcagaaataaacattgaaattgcaaagtgaaaaaaaaaaaaaaaaaa
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ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:9500 -> Molecular function: GO:0003713 [transcription coactivator activity] evidence: IEA GeneID:9500 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:9500 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: TAS GeneID:9500 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: IEA GeneID:9500 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS GeneID:9500 -> Biological process: GO:0042981 [regulation of apoptotic process] evidence: TAS GeneID:9500 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: TAS GeneID:9500 -> Biological process: GO:0043406 [positive regulation of MAP kinase activity] evidence: IEA GeneID:9500 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IEA GeneID:9500 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IEA GeneID:9500 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS GeneID:9500 -> Biological process: GO:0050680 [negative regulation of epithelial cell proliferation] evidence: IDA GeneID:9500 -> Biological process: GO:0090190 [positive regulation of branching involved in ureteric bud morphogenesis] evidence: IEA GeneID:9500 -> Biological process: GO:0097190 [apoptotic signaling pathway] evidence: TAS GeneID:9500 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA GeneID:9500 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA GeneID:9500 -> Cellular component: GO:0043234 [protein complex] evidence: IDA
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