2024-03-29 09:10:12, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001001933 2393 bp mRNA linear PRI 07-JUL-2013 DEFINITION Homo sapiens LIM homeobox 8 (LHX8), transcript variant 1, mRNA. ACCESSION NM_001001933 XM_086344 VERSION NM_001001933.1 GI:50083286 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2393) AUTHORS Jagarlamudi,K. and Rajkovic,A. TITLE Oogenesis: transcriptional regulators and mouse models JOURNAL Mol. Cell. Endocrinol. 356 (1-2), 31-39 (2012) PUBMED 21856374 REMARK Review article REFERENCE 2 (bases 1 to 2393) AUTHORS Paschou P, Stylianopoulou E, Karagiannidis I, Rizzo R, Tarnok Z, Wolanczyk T, Hebebrand J, Nothen MM, Lehmkuhl G, Farkas L, Nagy P, Szymanska U, Lykidis D, Androutsos C, Tsironi V, Koumoula A, Barta C, Klidonas S, Ypsilantis P, Simopoulos C, Skavdis G and Grigoriou M. CONSRTM TSGeneSEE Consortium TITLE Evaluation of the LIM homeobox genes LHX6 and LHX8 as candidates for Tourette syndrome JOURNAL Genes Brain Behav. 11 (4), 444-451 (2012) PUBMED 22435649 REMARK GeneRIF: Our tagging-single nucleotide polymorphism (tSNP)-based association analysis was negative for Tourette syndrome association with LHX8. REFERENCE 3 (bases 1 to 2393) AUTHORS Nat,R., Salti,A., Suciu,L., Strom,S. and Dechant,G. TITLE Pharmacological modulation of the Hedgehog pathway differentially affects dorsal/ventral patterning in mouse and human embryonic stem cell models of telencephalic development JOURNAL Stem Cells Dev. 21 (7), 1016-1046 (2012) PUBMED 22204396 REFERENCE 4 (bases 1 to 2393) AUTHORS Nikopensius,T., Kempa,I., Ambrozaityte,L., Jagomagi,T., Saag,M., Matuleviciene,A., Utkus,A., Krjutskov,K., Tammekivi,V., Piekuse,L., Akota,I., Barkane,B., Krumina,A., Klovins,J., Lace,B., Kucinskas,V. and Metspalu,A. TITLE Variation in FGF1, FOXE1, and TIMP2 genes is associated with nonsyndromic cleft lip with or without cleft palate JOURNAL Birth Defects Res. Part A Clin. Mol. Teratol. 91 (4), 218-225 (2011) PUBMED 21462296 REFERENCE 5 (bases 1 to 2393) AUTHORS Kim,J.Y., Jeon,S.H., Park,J.Y., Suh,J.D. and Choung,P.H. TITLE Comparative study of LHX8 expression between odontoma and dental tissue-derived stem cells JOURNAL J. Oral Pathol. Med. 40 (3), 250-256 (2011) PUBMED 21143530 REMARK GeneRIF: LHX8 might play an important role in odontoma formation. This is 1st report on comparison of LHX8 expression between human odontoma-derived mesenchymal cells and normal adult dental mesenchymal stem cells and its overexpression in human samples. REFERENCE 6 (bases 1 to 2393) AUTHORS Qin,Y., Zhao,H., Kovanci,E., Simpson,J.L., Chen,Z.J. and Rajkovic,A. TITLE Analysis of LHX8 mutation in premature ovarian failure JOURNAL Fertil. Steril. 89 (4), 1012-1014 (2008) PUBMED 17624344 REMARK GeneRIF: Mutations in the LHX8 exons are uncommon in Caucasian women with premature ovarian failure. GeneRIF: Observational study of gene-disease association. (HuGE Navigator) REFERENCE 7 (bases 1 to 2393) AUTHORS Suzumori,N., Pangas,S.A. and Rajkovic,A. TITLE Candidate genes for premature ovarian failure JOURNAL Curr. Med. Chem. 14 (3), 353-357 (2007) PUBMED 17305537 REMARK Review article REFERENCE 8 (bases 1 to 2393) AUTHORS Pangas,S.A., Choi,Y., Ballow,D.J., Zhao,Y., Westphal,H., Matzuk,M.M. and Rajkovic,A. TITLE Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8 JOURNAL Proc. Natl. Acad. Sci. U.S.A. 103 (21), 8090-8095 (2006) PUBMED 16690745 REMARK GeneRIF: Sohlh1 and Lhx8 are two germ cell-specific, critical regulators of oogenesis REFERENCE 9 (bases 1 to 2393) AUTHORS Vieira,A.R., Avila,J.R., Daack-Hirsch,S., Dragan,E., Felix,T.M., Rahimov,F., Harrington,J., Schultz,R.R., Watanabe,Y., Johnson,M., Fang,J., O'Brien,S.E., Orioli,I.M., Castilla,E.E., Fitzpatrick,D.R., Jiang,R., Marazita,M.L. and Murray,J.C. TITLE Medical sequencing of candidate genes for nonsyndromic cleft lip and palate JOURNAL PLoS Genet. 1 (6), E64 (2005) PUBMED 16327884 REMARK GeneRIF: Observational study of gene-disease association. (HuGE Navigator) REFERENCE 10 (bases 1 to 2393) AUTHORS Zhao,Y., Guo,Y.J., Tomac,A.C., Taylor,N.R., Grinberg,A., Lee,E.J., Huang,S. and Westphal,H. TITLE Isolated cleft palate in mice with a targeted mutation of the LIM homeobox gene lhx8 JOURNAL Proc. Natl. Acad. Sci. U.S.A. 96 (26), 15002-15006 (1999) PUBMED 10611327 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC099786.2 and BC040321.1. On Aug 30, 2004 this sequence version replaced gi:51458577. Summary: The protein encoded by this gene is a member of the LIM homeobox family of proteins, which are involved in patterning and differentiation of various tissue types. These proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040321.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025085 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3 AC099786.2 137235-137237 4-515 BC040321.1 4-515 516-516 AC099786.2 139367-139367 517-1553 BC040321.1 517-1553 1554-1554 AC099786.2 165773-165773 1555-2393 BC040321.1 1555-2393 FEATURES Location/Qualifiers source 1..2393 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="1" /map="1p31.1" gene 1..2393 /gene="LHX8" /gene_synonym="LHX7" /note="LIM homeobox 8" /db_xref="GeneID:431707" /db_xref="HGNC:28838" /db_xref="HPRD:17275" /db_xref="MIM:604425" exon 1..175 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 36 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="g" /db_xref="dbSNP:41289228" variation 71 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="t" /db_xref="dbSNP:182226067" exon 176..682 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 194 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="c" /db_xref="dbSNP:142466848" variation 223 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="c" /db_xref="dbSNP:192939997" variation 241 /gene="LHX8" /gene_synonym="LHX7" /replace="g" /replace="t" /db_xref="dbSNP:41289230" variation 433 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:111227275" variation 504 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:375399829" variation 595 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:41289232" variation 635 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:200867886" variation 646 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:200115972" variation 649 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:191646269" variation 653 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="g" /db_xref="dbSNP:41289234" misc_feature 656..658 /gene="LHX8" /gene_synonym="LHX7" /note="upstream in-frame stop codon" CDS 665..1735 /gene="LHX8" /gene_synonym="LHX7" /note="isoform 1 is encoded by transcript variant 1; LIM-homeodomain protein Lhx8; LIM/homeobox protein Lhx8" /codon_start=1 /product="LIM/homeobox protein Lhx8 isoform 1" /protein_id="NP_001001933.1" /db_xref="GI:50083287" /db_xref="CCDS:CCDS30756.1" /db_xref="GeneID:431707" /db_xref="HGNC:28838" /db_xref="HPRD:17275" /db_xref="MIM:604425" /translation="
MQILSRCQGLMSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSSAPLSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHSPTTLGLQPLLPHSMTQLPISHT
" misc_feature 884..1051 /gene="LHX8" /gene_synonym="LHX7" /note="The first LIM domain of Lhx7 and Lhx8; Region: LIM1_Lhx7_Lhx8; cd09381" /db_xref="CDD:188767" misc_feature order(887..889,896..898,950..952,959..961,968..970, 977..979,1034..1036,1043..1045) /gene="LHX8" /gene_synonym="LHX7" /note="Zn binding site [ion binding]; other site" /db_xref="CDD:188767" misc_feature 1070..1234 /gene="LHX8" /gene_synonym="LHX7" /note="The second LIM domain of Lhx7 and Lhx8; Region: LIM2_Lhx7_Lhx8; cd09383" /db_xref="CDD:188769" misc_feature order(1070..1072,1079..1081,1136..1138,1145..1147, 1154..1156,1163..1165,1220..1222,1229..1231) /gene="LHX8" /gene_synonym="LHX7" /note="Zn binding site [ion binding]; other site" /db_xref="CDD:188769" misc_feature 1340..1513 /gene="LHX8" /gene_synonym="LHX7" /note="Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; Region: homeodomain; cd00086" /db_xref="CDD:28970" misc_feature order(1340..1354,1358..1360,1409..1411,1427..1429, 1466..1468,1472..1477,1484..1489,1493..1501,1505..1510) /gene="LHX8" /gene_synonym="LHX7" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:28970" misc_feature order(1346..1348,1355..1357,1475..1477,1484..1489, 1496..1498) /gene="LHX8" /gene_synonym="LHX7" /note="specific DNA base contacts [nucleotide binding]; other site" /db_xref="CDD:28970" variation 675 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:202103118" exon 683..769 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 695 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="c" /db_xref="dbSNP:116590034" variation 713 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:376772505" variation 744 /gene="LHX8" /gene_synonym="LHX7" /replace="g" /replace="t" /db_xref="dbSNP:143612358" variation 754 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:140847718" variation 765 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:369761078" exon 770..931 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 775 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:369347146" variation 786 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:141641179" variation 792 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:373338242" variation 811 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:371247581" variation 814 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="g" /db_xref="dbSNP:145195318" variation 817 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:371111953" variation 842 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="g" /db_xref="dbSNP:376300206" variation 907 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:149422695" exon 932..1053 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 936 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="t" /db_xref="dbSNP:373880349" variation 1001 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="t" /db_xref="dbSNP:199843823" exon 1054..1274 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 1068 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:367958622" variation 1084 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:148556375" variation 1090 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:376834338" variation 1100 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:371719492" variation 1105 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:12084309" variation 1108 /gene="LHX8" /gene_synonym="LHX7" /replace="g" /replace="t" /db_xref="dbSNP:374741343" variation 1264 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:372110957" exon 1275..1378 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 1276 /gene="LHX8" /gene_synonym="LHX7" /replace="g" /replace="t" /db_xref="dbSNP:376728766" variation 1300 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:147867930" exon 1379..1474 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" exon 1475..1658 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 1477 /gene="LHX8" /gene_synonym="LHX7" /replace="g" /replace="t" /db_xref="dbSNP:79714503" variation 1513 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:941032" variation 1521 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="g" /db_xref="dbSNP:200810970" variation 1559 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="c" /db_xref="dbSNP:201945188" variation 1564 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:144728419" variation 1567 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="g" /db_xref="dbSNP:375095039" variation 1591 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="t" /db_xref="dbSNP:368509617" variation 1609 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:370428970" variation 1610 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:374046822" variation 1627 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:145367581" variation 1638 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:34889650" exon 1659..2373 /gene="LHX8" /gene_synonym="LHX7" /inference="alignment:Splign:1.39.8" variation 1706 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:368782371" variation 1714 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="c" /db_xref="dbSNP:377005651" variation 1769 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="t" /db_xref="dbSNP:41306167" variation 1784 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:199821156" variation 1786 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:41301265" variation 1833 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:184821578" variation 1930 /gene="LHX8" /gene_synonym="LHX7" /replace="g" /replace="t" /db_xref="dbSNP:187614610" variation 2008 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:374351080" variation 2045 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="t" /db_xref="dbSNP:192190181" variation 2099 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:142785057" variation 2152 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:184182933" variation 2213 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:147403016" variation 2299 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:190197837" variation 2311 /gene="LHX8" /gene_synonym="LHX7" /replace="a" /replace="g" /db_xref="dbSNP:4949795" polyA_signal 2341..2346 /gene="LHX8" /gene_synonym="LHX7" variation 2352 /gene="LHX8" /gene_synonym="LHX7" /replace="c" /replace="t" /db_xref="dbSNP:377666437" polyA_site 2373 /gene="LHX8" /gene_synonym="LHX7" ORIGIN
agaggcaagaggctagcggctggaccacttgtgctggagtggtaaagaactatcatgaatccatttactgaaagtgtccatttctgaactcaccctaaagaggacaaacaccgcaaagtagttaaaagtcaggcattcgcgtcggacgtctgggtttgaattctgccctggcttgactggaaacgcttcccctatttcttccgtagcggaccgggagagcttactggcgctctgcgaaccggctggaaagaaacaccgagtcactcgtacagactcttggtcgcagaacttggctttccgctattggtcctccagaaccgcttgaaacaactggccccagctggcgcatcagaccgcagtgaggaatgccgcggggcgggtggcgaaggcagggtctgcccgccagtggattcccgggtgtcccgcgtggagcaggcttgcccagctgggaagcccatcaaacctcagtcttggcccacagtgggagagagaccagtgggtcccagacggaggccctcgcccgcttttggcgacctccactggcgtgaataaaagcacccctctcttaccctcagaaactgtgggtagcaaggtataaaacggagtctgggaccggtaagtcccaaggtgagcccgtatacagctctgccatctctgaggggttatgcagattctgagcaggtgtcaggggctcatgtcagaggagtgcgggcggactacagccctggcggccgggaggactcgcaaaggcgccggggaagagggactggtgagccccgagggagcgggggacgaggactcgtgctcctcctcggccccgctgtccccgtcgtcctcgccccggtccatggcctcgggctccggctgccctcctggcaagtgtgtgtgcaacagttgcggcctggagatcgtggacaaataccttctcaaggtgaatgacctatgctggcatgtccggtgtctctcctgcagtgtttgcagaacctccctaggaaggcacaccagctgttatattaaagacaaagacattttctgcaaacttgattatttcagaaggtatggaactcgctgctctcgatgtgggagacacatccattctactgactgggtccggagagccaaggggaatgtctatcacttggcatgctttgcctgcttttcctgcaaaaggcaactttccacaggagaggagtttgctttggtggaagagaaagtcctctgcagagtacattatgactgcatgctggataatttaaaaagagaagtagaaaatgggaatgggattagtgtggaaggtgccctcctcacagagcaagatgttaaccatccaaaaccagcaaaaagagctcggaccagctttacagcagatcagcttcaggttatgcaagcacaatttgctcaggacaacaacccagatgcacagacactccagaaattggcagaaaggacaggcttgagcagacgtgtgatacaggtgtggtttcagaattgtagagcacgccacaagaaacacgtcagtcctaatcactcatcctccaccccagtcacagcagtcccaccctccaggctgtctccacccatgttagaagaaatggcttattctgcctacgtgccccaagatggaacgatgttaactgcgctgcatagttatatggatgctcattcaccaacaactcttggactccagcccttgttaccccattcaatgacacaactgccaataagtcatacctaattcttttttcagggatagacttgattaaggatataaatttgtcatttattatgtataaaataccattgaaaagatattactgttaattttttatttaacacctaaagcatttccaacatcactttgctgcccaggtatgtatctatagttggcctgcaagacacttttattaattcttcattttttgtaaaacttatgtttacaagaagaaaacaaatcaaaacattttttgtattgtctggaaatagttcactctagtgtgtatctgttaatttatttgtcatcaaaagagcactttgcctaaaagaaaggactgacaagtgtgcaaaatgtttacaatcttttgtgaaattgtagtttatcattagtttgtatctgtaagttattgtaataaatattacctgtattttttgttatatacaactttatactttgaagcttgtatctgtgaatttgcaactgaaatttattttgccaatgttttctgaatgaactgaataaagcttctgttgtagcatgccatgcaaacacattattgtgtttgtggttgatgaattatggctgtaaataacactatagtttaataagcccaccattctgagtttattaaacattttccattcttgtgaaaatttcaaaaaaaaaaaaaaaaaaaaaa
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ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:431707 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA GeneID:431707 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA GeneID:431707 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA GeneID:431707 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA GeneID:431707 -> Biological process: GO:0007611 [learning or memory] evidence: IEA GeneID:431707 -> Biological process: GO:0008585 [female gonad development] evidence: IEA GeneID:431707 -> Biological process: GO:0021884 [forebrain neuron development] evidence: IEA GeneID:431707 -> Biological process: GO:0042475 [odontogenesis of dentin-containing tooth] evidence: IEA GeneID:431707 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
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