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2020-10-24 06:56:08, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_000661                766 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens ribosomal protein L9 (RPL9), transcript variant 1,
            mRNA.
ACCESSION   NM_000661
VERSION     NM_000661.4  GI:72377390
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm. Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
REFERENCE   2  (bases 1 to 766)
  AUTHORS   Andersen,J.S., Lam,Y.W., Leung,A.K., Ong,S.E., Lyon,C.E.,
            Lamond,A.I. and Mann,M.
  TITLE     Nucleolar proteome dynamics
  JOURNAL   Nature 433 (7021), 77-83 (2005)
   PUBMED   15635413
REFERENCE   3  (bases 1 to 766)
  AUTHORS   Kapp,L.D. and Lorsch,J.R.
  TITLE     The molecular mechanics of eukaryotic translation
  JOURNAL   Annu. Rev. Biochem. 73, 657-704 (2004)
   PUBMED   15189156
  REMARK    Review article
REFERENCE   4  (bases 1 to 766)
  AUTHORS   Mazumder,B., Sampath,P., Seshadri,V., Maitra,R.K., DiCorleto,P.E.
            and Fox,P.L.
  TITLE     Regulated release of L13a from the 60S ribosomal subunit as a
            mechanism of transcript-specific translational control
  JOURNAL   Cell 115 (2), 187-198 (2003)
   PUBMED   14567916
REFERENCE   5  (bases 1 to 766)
  AUTHORS   Odintsova,T.I., Muller,E.C., Ivanov,A.V., Egorov,T.A., Bienert,R.,
            Vladimirov,S.N., Kostka,S., Otto,A., Wittmann-Liebold,B. and
            Karpova,G.G.
  TITLE     Characterization and analysis of posttranslational modifications of
            the human large cytoplasmic ribosomal subunit proteins by mass
            spectrometry and Edman sequencing
  JOURNAL   J. Protein Chem. 22 (3), 249-258 (2003)
   PUBMED   12962325
REFERENCE   6  (bases 1 to 766)
  AUTHORS   Andersen,J.S., Lyon,C.E., Fox,A.H., Leung,A.K., Lam,Y.W., Steen,H.,
            Mann,M. and Lamond,A.I.
  TITLE     Directed proteomic analysis of the human nucleolus
  JOURNAL   Curr. Biol. 12 (1), 1-11 (2002)
   PUBMED   11790298
REFERENCE   7  (bases 1 to 766)
  AUTHORS   Kenmochi,N., Kawaguchi,T., Rozen,S., Davis,E., Goodman,N.,
            Hudson,T.J., Tanaka,T. and Page,D.C.
  TITLE     A map of 75 human ribosomal protein genes
  JOURNAL   Genome Res. 8 (5), 509-523 (1998)
   PUBMED   9582194
REFERENCE   8  (bases 1 to 766)
  AUTHORS   Mazuruk,K., Schoen,T.J., Chader,G.J., Iwata,T. and Rodriguez,I.R.
  TITLE     Structural organization and chromosomal localization of the human
            ribosomal protein L9 gene
  JOURNAL   Biochim. Biophys. Acta 1305 (3), 151-162 (1996)
   PUBMED   8597601
REFERENCE   9  (bases 1 to 766)
  AUTHORS   Wool,I.G., Chan,Y.L. and Gluck,A.
  TITLE     Structure and evolution of mammalian ribosomal proteins
  JOURNAL   Biochem. Cell Biol. 73 (11-12), 933-947 (1995)
   PUBMED   8722009
  REMARK    Review article
REFERENCE   10 (bases 1 to 766)
  AUTHORS   Hori,N., Murakawa,K., Matoba,R., Fukushima,A., Okubo,K. and
            Matsubara,K.
  TITLE     A new human ribosomal protein sequence, homologue of rat L9
  JOURNAL   Nucleic Acids Res. 21 (18), 4395 (1993)
   PUBMED   8415001
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Francesco Amaldi. The reference sequence was
            derived from BM841336.1, BC066318.1 and BC031906.1.
            On Aug 11, 2005 this sequence version replaced gi:67944628.
            
            Summary: Ribosomes, the organelles that catalyze protein synthesis,
            consist of a small 40S subunit and a large 60S subunit. Together
            these subunits are composed of 4 RNA species and approximately 80
            structurally distinct proteins. This gene encodes a ribosomal
            protein that is a component of the 60S subunit. The protein belongs
            to the L6P family of ribosomal proteins. It is located in the
            cytoplasm. As is typical for genes encoding ribosomal proteins,
            there are multiple processed pseudogenes of this gene dispersed
            through the genome. Two alternatively spliced transcript variants
            encoding the same protein have been found for this gene. [provided
            by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) represents the shorter
            transcript and the predominant variant. Variants 1 and 2 encode the
            same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CD247802.1, CD173747.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                BM841336.1         1-33
            34-737              BC066318.1         1-704
            738-766             BC031906.1         685-713
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p13"
     gene            1..766
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /note="ribosomal protein L9"
                     /db_xref="GeneID:6133"
                     /db_xref="HGNC:10369"
                     /db_xref="HPRD:04732"
                     /db_xref="MIM:603686"
     exon            1..58
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    1
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /note="5'-most of multiple alternative transcription
                     initiation sites"
     variation       6
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:17553177"
     misc_feature    34
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /note="predominant transcription initiation site"
     exon            59..105
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /inference="alignment:Splign:1.39.8"
     CDS             60..638
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /codon_start=1
                     /product="60S ribosomal protein L9"
                     /protein_id="NP_000652.2"
                     /db_xref="GI:15431303"
                     /db_xref="CCDS:CCDS3452.1"
                     /db_xref="GeneID:6133"
                     /db_xref="HGNC:10369"
                     /db_xref="HPRD:04732"
                     /db_xref="MIM:603686"
                     /translation="
MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE
"
     misc_feature    60..632
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /note="60S ribosomal protein L6; Provisional; Region:
                     PTZ00027"
                     /db_xref="CDD:240234"
     misc_feature    60..62
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Not acetylated; propagated from
                     UniProtKB/Swiss-Prot (P32969.1); other site"
     misc_feature    93..320
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /note="Ribosomal protein L6; Region: Ribosomal_L6;
                     pfam00347"
                     /db_xref="CDD:215872"
     misc_feature    354..593
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /note="Ribosomal protein L6; Region: Ribosomal_L6;
                     pfam00347"
                     /db_xref="CDD:215872"
     misc_feature    420..422
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine; propagated from
                     UniProtKB/Swiss-Prot (P32969.1); acetylation site"
     exon            106..221
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /inference="alignment:Splign:1.39.8"
     exon            222..317
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /inference="alignment:Splign:1.39.8"
     exon            318..450
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /inference="alignment:Splign:1.39.8"
     variation       425
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2125313"
     exon            451..531
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /inference="alignment:Splign:1.39.8"
     STS             509..680
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /standard_name="D4S3187"
                     /db_xref="UniSTS:28767"
     STS             526..685
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /standard_name="RH67836"
                     /db_xref="UniSTS:84205"
     exon            532..648
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /inference="alignment:Splign:1.39.8"
     exon            649..750
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /inference="alignment:Splign:1.39.8"
     polyA_signal    715..720
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
     variation       716
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1802628"
     polyA_site      737
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
     polyA_site      750
                     /gene="RPL9"
                     /gene_synonym="L9; NPC-A-16"
ORIGIN      
acgcgatacaagtacgtaatgacgacagacgttctttctttgctgcgtctactgcgagaatgaagactattctcagcaatcagactgtcgacattccagaaaatgtcgacattactctgaagggacgcacagttatcgtgaagggccccagaggaaccctgcggagggacttcaatcacatcaatgtagaactcagccttcttggaaagaaaaaaaagaggctccgggttgacaaatggtggggtaacagaaaggaactggctaccgttcggactatttgtagtcatgtacagaacatgatcaagggtgttacactgggcttccgttacaagatgaggtctgtgtatgctcacttccccatcaacgttgttatccaggagaatgggtctcttgttgaaatccgaaatttcttgggtgaaaaatatatccgcagggttcggatgagaccaggtgttgcttgttcagtatctcaagcccagaaagatgaattaatccttgaaggaaatgacattgagcttgtttcaaattcagcggctttgattcagcaagccacaacagttaaaaacaaggatatcaggaaatttttggatggtatctatgtctctgaaaaaggaactgttcagcaggctgatgaataagatctaagagttacctggctacagaaagaagatgccagatgacacttaagacctacttgtgatatttaaatgatgcaataaaagacctattgatttggaccttcttcttaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:6133 -> Molecular function: GO:0003723 [RNA binding] evidence: TAS
            GeneID:6133 -> Molecular function: GO:0003735 [structural constituent of ribosome] evidence: NAS
            GeneID:6133 -> Molecular function: GO:0019843 [rRNA binding] evidence: IEA
            GeneID:6133 -> Biological process: GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] evidence: TAS
            GeneID:6133 -> Biological process: GO:0006412 [translation] evidence: NAS
            GeneID:6133 -> Biological process: GO:0006412 [translation] evidence: TAS
            GeneID:6133 -> Biological process: GO:0006413 [translational initiation] evidence: TAS
            GeneID:6133 -> Biological process: GO:0006414 [translational elongation] evidence: TAS
            GeneID:6133 -> Biological process: GO:0006415 [translational termination] evidence: TAS
            GeneID:6133 -> Biological process: GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] evidence: TAS
            GeneID:6133 -> Biological process: GO:0010467 [gene expression] evidence: TAS
            GeneID:6133 -> Biological process: GO:0016032 [viral process] evidence: TAS
            GeneID:6133 -> Biological process: GO:0016070 [RNA metabolic process] evidence: TAS
            GeneID:6133 -> Biological process: GO:0016071 [mRNA metabolic process] evidence: TAS
            GeneID:6133 -> Biological process: GO:0019058 [viral infectious cycle] evidence: TAS
            GeneID:6133 -> Biological process: GO:0019083 [viral transcription] evidence: TAS
            GeneID:6133 -> Biological process: GO:0044267 [cellular protein metabolic process] evidence: TAS
            GeneID:6133 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:6133 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:6133 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:6133 -> Cellular component: GO:0005840 [ribosome] evidence: TAS
            GeneID:6133 -> Cellular component: GO:0022625 [cytosolic large ribosomal subunit] evidence: IDA

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