2024-03-28 23:14:01, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_000486 4288 bp mRNA linear PRI 07-JUL-2013 DEFINITION Homo sapiens aquaporin 2 (collecting duct) (AQP2), mRNA. ACCESSION NM_000486 VERSION NM_000486.5 GI:209180415 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 4288) AUTHORS Bockenhauer,D. and Bichet,D.G. TITLE Inherited secondary nephrogenic diabetes insipidus: concentrating on humans JOURNAL Am. J. Physiol. Renal Physiol. 304 (8), F1037-F1042 (2013) PUBMED 23364801 REMARK GeneRIF: Investigations into primary inherited nephrogenic diabetes insipidus (NDI) have contributed enormously to our understanding of the mechanisms of urinary concentration and identified the vasopressin receptor AVPR2, as well as the water channel aquaporin-2. Review article REFERENCE 2 (bases 1 to 4288) AUTHORS Wu,H., Chen,L., Zhang,X., Zhou,Q., Li,J.M., Berger,S., Borok,Z., Zhou,B., Xiao,Z., Yin,H., Liu,M., Wang,Y., Jin,J., Blackburn,M.R., Xia,Y. and Zhang,W. TITLE Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2 JOURNAL PLoS ONE 8 (1), E53342 (2013) PUBMED 23326416 REMARK GeneRIF: upregulated Aqp5 may contribute to polyuria, possibly by impairing Aqp2 membrane localization, in Dot1l(AC) mice and in patients with diabetic nephropathy. REFERENCE 3 (bases 1 to 4288) AUTHORS Sasaki,S. TITLE Aquaporin 2: from its discovery to molecular structure and medical implications JOURNAL Mol. Aspects Med. 33 (5-6), 535-546 (2012) PUBMED 23078817 REMARK GeneRIF: AQP2 is greatly involved in many human abnormal water balance disorders. (Review) Review article REFERENCE 4 (bases 1 to 4288) AUTHORS Schenk,A.D., Werten,P.J., Scheuring,S., de Groot,B.L., Muller,S.A., Stahlberg,H., Philippsen,A. and Engel,A. TITLE The 4.5 A structure of human AQP2 JOURNAL J. Mol. Biol. 350 (2), 278-289 (2005) PUBMED 15922355 REMARK GeneRIF: crystallization of recombinantly expressed human AQP2 into two-dimensional protein-lipid arrays and their structural characterization by atomic force microscopy and electron crystallography REFERENCE 5 (bases 1 to 4288) AUTHORS Ma,T., Yang,B., Umenishi,F. and Verkman,A.S. TITLE Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13 JOURNAL Genomics 43 (3), 387-389 (1997) PUBMED 9268644 REFERENCE 6 (bases 1 to 4288) AUTHORS Saito,F., Sasaki,S., Chepelinsky,A.B., Fushimi,K., Marumo,F. and Ikeuchi,T. TITLE Human AQP2 and MIP genes, two members of the MIP family, map within chromosome band 12q13 on the basis of two-color FISH JOURNAL Cytogenet. Cell Genet. 68 (1-2), 45-48 (1995) PUBMED 7525161 REFERENCE 7 (bases 1 to 4288) AUTHORS van Lieburg,A.F., Verdijk,M.A., Knoers,V.V., van Essen,A.J., Proesmans,W., Mallmann,R., Monnens,L.A., van Oost,B.A., van Os,C.H. and Deen,P.M. TITLE Patients with autosomal nephrogenic diabetes insipidus homozygous for mutations in the aquaporin 2 water-channel gene JOURNAL Am. J. Hum. Genet. 55 (4), 648-652 (1994) PUBMED 7524315 REFERENCE 8 (bases 1 to 4288) AUTHORS Uchida,S., Sasaki,S., Fushimi,K. and Marumo,F. TITLE Isolation of human aquaporin-CD gene JOURNAL J. Biol. Chem. 269 (38), 23451-23455 (1994) PUBMED 7522228 REFERENCE 9 (bases 1 to 4288) AUTHORS Sasaki,S., Fushimi,K., Saito,H., Saito,F., Uchida,S., Ishibashi,K., Kuwahara,M., Ikeuchi,T., Inui,K., Nakajima,K. et al. TITLE Cloning, characterization, and chromosomal mapping of human aquaporin of collecting duct JOURNAL J. Clin. Invest. 93 (3), 1250-1256 (1994) PUBMED 7510718 REMARK Erratum:[J Clin Invest 1994 Nov;94(5):following 216] REFERENCE 10 (bases 1 to 4288) AUTHORS Deen,P.M., Weghuis,D.O., Sinke,R.J., Geurts van Kessel,A., Wieringa,B. and van Os,C.H. TITLE Assignment of the human gene for the water channel of renal collecting duct Aquaporin 2 (AQP2) to chromosome 12 region q12-->q13 JOURNAL Cytogenet. Cell Genet. 66 (4), 260-262 (1994) PUBMED 7512890 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK225940.1, AI792401.1, BC042496.1 and AC025154.31. This sequence is a reference standard in the RefSeqGene project. On Oct 9, 2008 this sequence version replaced gi:186910297. Summary: This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC042496.1, S73196.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025084, ERS025085 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-719 AK225940.1 1-719 720-1066 AI792401.1 44-390 1067-2467 BC042496.1 1062-2462 2468-3908 AC025154.31 9560-11000 3909-4288 BC042496.1 3904-4283 FEATURES Location/Qualifiers source 1..4288 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="12" /map="12q12-q13" gene 1..4288 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /note="aquaporin 2 (collecting duct)" /db_xref="GeneID:359" /db_xref="HGNC:634" /db_xref="HPRD:00141" /db_xref="MIM:107777" exon 1..450 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="alignment:Splign:1.39.8" variation 16 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:149553671" variation 25 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:143249649" variation 32 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:62620006" variation 40 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:374778728" variation 43 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:141361202" misc_feature 55..57 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /note="upstream in-frame stop codon" variation 75 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:200777769" variation 81 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:370614216" CDS 91..906 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /note="water-channel aquaporin 2; collecting duct water channel protein; aquaporin-CD; AQP-2; ADH water channel; water channel protein for renal collecting duct" /codon_start=1 /product="aquaporin-2" /protein_id="NP_000477.1" /db_xref="GI:4502179" /db_xref="CCDS:CCDS8792.1" /db_xref="GeneID:359" /db_xref="HGNC:634" /db_xref="HPRD:00141" /db_xref="MIM:107777" /translation="
MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGTKA
" misc_feature 121..756 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /note="Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333" /db_xref="CDD:29423" misc_feature 139..192 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P41181.1); transmembrane region" misc_feature 211..267 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P41181.1); transmembrane region" misc_feature order(232..234,286..294,628..633,640..642,649..651) /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /note="amphipathic channel; other site" /db_xref="CDD:29423" misc_feature order(292..300,640..648) /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /note="Asn-Pro-Ala signature motifs; other site" /db_xref="CDD:29423" misc_feature 292..300 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P41181.1); Region: NPA 1" misc_feature 346..411 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P41181.1); transmembrane region" misc_feature 472..534 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P41181.1); transmembrane region" misc_feature 559..618 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P41181.1); transmembrane region" misc_feature 640..648 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P41181.1); Region: NPA 2" misc_feature 697..762 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P41181.1); transmembrane region" misc_feature 856..858 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine, by PKA; propagated from UniProtKB/Swiss-Prot (P41181.1); phosphorylation site" misc_feature 856..858 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" variation 101 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:372883230" variation 104 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:148006652" variation 117 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:187754589" variation 122 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:148085137" variation 129 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:61733029" variation 141 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:377296676" variation 153 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:147136099" variation 154 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:104894336" variation 160 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:200706192" variation 174 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:373926562" variation 177 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:139709797" variation 231 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:140262864" variation 252 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:143497314" variation 260 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:28931580" variation 262 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:145685755" variation 270 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:370848842" variation 279 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:200279968" variation 280 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:104894326" variation 284 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:147174725" variation 293 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:104894331" variation 294 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:57915981" variation 300 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:139893949" variation 301 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:149659001" variation 313 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:193922494" variation 314 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:144443773" variation 322 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:149823093" variation 366 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:148785923" variation 389 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:104894338" variation 394 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /replace="t" /db_xref="dbSNP:201047682" variation 399 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:11557014" variation 414 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:143940351" variation 429 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:144253988" variation 430 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:370232864" variation 432 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:35400945" variation 435 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:60629501" exon 451..615 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="alignment:Splign:1.39.8" variation 451 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:11169226" variation 464 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:104894333" variation 467 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:104894330" variation 468 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:144891220" variation 480 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:139064235" variation 483 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:371158770" variation 513 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:151219353" variation 523 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:373700329" variation 528 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:143886391" variation 529 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:104894334" variation 536 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:146384248" variation 537 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:369985708" variation 545 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:150344189" variation 548 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:139771821" variation 549 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:201617819" variation 550 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:369214822" variation 561 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:138000704" variation 591 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:426496" variation 613 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:104894335" exon 616..696 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="alignment:Splign:1.39.8" variation 627 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:199999215" variation 628 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:147039983" variation 633 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:104894337" variation 649 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:104894328" variation 650 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:193922495" variation 658 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:104894341" variation 669 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:201812544" exon 697..4179 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /inference="alignment:Splign:1.39.8" variation 714 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:201300211" variation 725 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:142323499" variation 736 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:104894329" variation 737 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:199422215" variation 741 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:145940884" variation 765 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:139738521" variation 792 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:143104356" variation 819 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:201761847" variation 825 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:201195539" variation 841 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:150666967" variation 848 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:139913957" variation 853 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:370879515" variation 862 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:104894332" variation 872 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:376000406" variation 875 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="c" /db_xref="dbSNP:193922496" variation 875 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:104894339" variation 926 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:457487" variation 993 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:145741662" variation 1027 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:75528468" variation 1132 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:145323624" variation 1146 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="t" /db_xref="dbSNP:1047224" variation 1156 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:373992535" variation 1157 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:35872356" variation 1158 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:114099597" variation 1176 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:368208178" variation 1187 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:142263071" STS 1214..1383 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /standard_name="STS-D31846" /db_xref="UniSTS:41469" variation 1223 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:143209925" variation 1227 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:151189685" variation 1265..1266 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="g" /db_xref="dbSNP:34335497" variation 1275 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:140262155" variation 1277 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="t" /db_xref="dbSNP:35146277" variation 1280 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:467323" variation 1292 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="t" /db_xref="dbSNP:137959340" variation 1298 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="t" /db_xref="dbSNP:35190790" variation 1319 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="t" /db_xref="dbSNP:35104166" variation 1330 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:56160615" variation 1331 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:149425435" variation 1379 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:185701115" variation 1436 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:74091160" variation 1447 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:144600878" variation 1457 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:375057124" polyA_signal 1458..1463 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" variation 1466 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:138553011" variation 1471 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:143040820" polyA_site 1478 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" variation 1494 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:144410593" variation 1545 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:148800696" variation 1607 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:190748197" variation 1610 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:141505727" variation 1666 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:369989916" variation 1779 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:150878207" variation 1785 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:139933330" variation 1789 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:374844138" variation 1793 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:145489632" variation 1807 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:147666604" variation 1813 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:60887132" variation 1814 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:149776268" variation 1817 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:145603433" variation 1882 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:372756747" variation 1907 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:148904180" variation 1929 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:143529505" variation 1952 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:146499105" variation 1993 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:186839162" variation 2124 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:376984675" variation 2134 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:77904078" variation 2285 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:144704751" variation 2291 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:138521926" variation 2301 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:140054228" variation 2313 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="t" /db_xref="dbSNP:150302183" variation 2314 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:138918672" variation 2330 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:149432877" variation 2372 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:144781042" variation 2448 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:138508276" variation 2452 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:143902080" variation 2468 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:296766" variation 2531..2532 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="g" /db_xref="dbSNP:34780794" variation 2544 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:140840803" variation 2557 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:142248293" variation 2565 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:150827515" variation 2570 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /replace="t" /db_xref="dbSNP:139195477" variation 2575 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:149970166" variation 2590 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:10875989" variation 2636 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="t" /db_xref="dbSNP:141050726" variation 2663 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:74091162" variation 2678 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:146686241" variation 2684 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:148850890" variation 2753 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:113705802" variation 2779 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:147991678" variation 2849 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:140601595" variation 2852 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:144000063" variation 2923 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:147121391" variation 2953 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:138464500" variation 2975..2976 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="a" /db_xref="dbSNP:146460961" variation 3007 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:77661963" variation 3036 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:147299953" variation 3046 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:139100177" variation 3090 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="t" /db_xref="dbSNP:149388266" variation 3138 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="c" /db_xref="dbSNP:142286713" variation 3156 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:296767" variation 3179 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:142678894" variation 3182 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:146020668" variation 3185 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:139981875" variation 3195..3198 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="tctc" /db_xref="dbSNP:34614799" variation 3198..3201 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="ctct" /db_xref="dbSNP:72283122" variation 3198 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:201471282" variation 3206 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:146727766" variation 3217 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:192037751" variation 3258 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:149742362" variation 3265 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:140184713" variation 3285 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:149916875" variation 3390 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:145588525" variation 3401 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:296768" variation 3448 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:149042011" variation 3519 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:376235969" variation 3521 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:148876709" variation 3528 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:145783831" variation 3537 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:147733377" variation 3621 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:142648983" variation 3631 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:1077520" variation 3701 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:1077521" variation 3742 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:141457763" variation 3744 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:113903023" variation 3747 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:138229213" variation 3778 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:142738661" variation 3785 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /replace="t" /db_xref="dbSNP:146060042" variation 3786 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="g" /replace="t" /db_xref="dbSNP:139949172" variation 3822 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:141894535" variation 3832 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:187623325" variation 3865 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="c" /db_xref="dbSNP:2336709" variation 3870 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:147698325" variation 3878..3879 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="" /replace="t" /db_xref="dbSNP:34704996" variation 3889 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:146241781" variation 3908 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="g" /db_xref="dbSNP:2878771" variation 3930 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:142554418" variation 3994 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:150948503" variation 3999 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:371072705" variation 4010 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:116924705" variation 4074 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="c" /replace="t" /db_xref="dbSNP:2878772" variation 4095 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:147782490" variation 4109 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:142636775" variation 4153 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:142405052" polyA_signal 4157..4162 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" variation 4176 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" /replace="a" /replace="g" /db_xref="dbSNP:146912406" polyA_site 4179 /gene="AQP2" /gene_synonym="AQP-CD; WCH-CD" ORIGIN
cttgagaaagagagcgatagagtgcgagagcgagtgcccggagcatcctggccctgagacagctgggccagccccgcagggctctgcagcatgtgggagctccgctccatagccttctccagggctgtgttcgcagagttcctggccacactcctcttcgtcttctttggcctcggctctgccctcaactggccacaggccctgccctctgtgctacagattgccatggcgtttggcttgggtattggcaccctggtacaggctctgggccacataagcggggcccacatcaaccctgccgtgactgtggcctgcctggtgggctgccacgtctccgttctccgagccgccttctacgtggctgcccagctgctgggggctgtggccggagccgctctgctccatgagatcacgccagcagacatccgcggggacctggctgtcaatgctctcagcaacagcacgacggctggccaggcggtgactgtggagctcttcctgacactgcagctggtgctctgcatcttcgcctccaccgatgagcgccgcggagagaacccgggcacccctgctctctccataggcttctccgtggccctgggccacctccttgggatccattacaccggctgctctatgaatcctgcccgctccctggctccagctgtcgtcactggcaaatttgatgaccactgggtcttctggatcggacccctggtgggcgccatcctgggctccctcctctacaactacgtgctgtttccgccagccaagagcctgtcggagcgcctggcagtgctgaagggcctggagccggacaccgattgggaggagcgcgaggtgcgacggcggcagtcggtggagctgcactcgccgcagagcctgccacggggtaccaaggcctgagggccgccagcggcctctaaggccccgacggacgcttgtgaggcccgaggcagaagggcccaccccgtccctcctctcccgcaggtctgaagttggccccccagcgcagagtagctgcttcctggacgtgcgcgcccaggccagtgctgtgagcaggcggggaggaggctgccggagggagccctgagcctggcaggtcccctgccctgaggctgtgagcagctagtggtggcttctccagcctttttcagggaactgggaacttaggggactgagctggggagggaggcaggtgggtggtaagagggaaactctggagagcctgcacccaggtactgagtggggagtgtacagacccctgccttgggggttccgggaatgatgcaactggttttactagtgtgcaagtgtgttcatccccaagttctcttttgtcctcacatgcagagttgtgcatgcccctgagtgtgaacaggtttgcctacgttggtgcaagtgtgcatggctggggacttctcacttccccttgcaccccttcctccccaacctgcaataaatccgcttctcctgcagtggatgagtgtgggtgccagtcctcctcaggagaaggggaagggaaggaggccactttgagagggctgaagggagggccttgatttccagccgcaatctggctcctcctggaaaatttcccccacctgcagcgctgggccccaaggcttgccaagactcattgctggaggtagagaggtgtcaaccagagaacagctcccctagacatggcctctggaaaaaggaaatctttggtggccaaagatttcctttctgtggtgagggagaacctctccaaagaggaagcaggcatatgagtgcgcacgccttcacgtgtgtgtatgctgtgtgtgcccgggacccccgtctccaggggtgccccagacccagagattagcctcccacttcggcgcagaaaacaaaagccctttgtgggacccgggcctttgtcttgggtgaggggagatttgcacctagacacttcttgaaaggagacactcagtttcacaagtgagccctcttgcccagcacacacctatggctggctgggcaaggcgctcaggcatgcaaccatgggcaccaggcaatacccatccatcacccatctcactctccccagtcctcaggcagcagcttttccaccccaggaatctctgttccttctctgtctgcctctccacagcccgtgatcccctgcttctggctcctaccactggacagtcattgtggatagagcagcctgctgctctcaggaccagagaagggaaatgacttctccaggcagaggcagatctgagtctagaacccaggcttctaaatttctaggccagtactactgctctcaaaagagattaactgggattaagtgagatgacgcatgtaaagatgctgtgtaaactgtaattcttaataccattatcacgcattactagaatcatttcattatttctgcttcctgggggaaggatgcagaaggagtctgatgctcaacatcccttacctcctttcgttgatggccaaagcaaaggagagtcctgggagcccacaagatccaggcagaaggagatgggtttggggctggccccatcctggcccagcctcttaacctcttcttaccctgaatgtgtgccctatcttttctcccacctccttcctcctaccacccagccctatccattctctccttccctctccagcctgctgtataagtaacatgtgggtcataccttgaacccccctccgcccccatgctctctgtggcctccatgccttcaagacttctgtctgtatctatctcacactgcaccaagcacccactgtgcaccaggcactaagtctctagcctctttctcccttctgctcccatccaagaaagacagtgtataaggaacatctctgtaattgtgtcccctctcatctatgctctttcctgtcttccttgaccaaagctctctttgaggtccaaaaaaggctgccctgggccatatgtgctatggagaggactctcccaaacccccaatagctagtgacagccacttggcctcactaccagaagaagggtggagtcagaaaccaaagtgacctccagagctgtcctcctggcacctgagtgtccttgctctagaggttcaaaggcagcaaggcagtgagctatgagcccagcatggatgtgtctcaggcacctcatccccaccccacctcaccccaacaaactcctctagaagaagccaagaatttctctctatgtctgtttcactttttggattgcatctccccaaaaactaaatgtgaaatccctaccatttctagcctctattgcccagattggagtcagaggtcaaaaaaggattccaagtgatggaactccaggggtggagggaaattggcagttcctggcatctcttgtgtaccagctgctgtgctgggtgccttgcatgcacggacttatctgatcttcctcaaacttcagataggttagggaaggacaaaggcccccagccatgaagggttttgctatttccaaagcttccccttatcgtcccctgtgattatctcccaaccccgtgacaaaggtagagcaaatattgttcttcccattttacagattcagaaaccaaggctaagggactggtctaaagtctcacaggtagtatatggtggagccaacacttgaactcagacctttttacacaaaatcccatgatttttccactgagacaaatcctaggctcctgggaggccctggcagaagccagaacacatggctgggcctttccagcccaacccactgtcttgcagtggacggagagccttggcgagggcagcagggtagagaggacaaagaatgtggggctggtttctgccctttaagagcacccggtcagtcagagaacagagatcacacacaccaaaccagacagaggcagggcagcatggagacaggtagacagacctccaggtccctaagctggggacagagaaggttctgagctgtcccatactcccactttgtgccaaatgactttgcacctgcaaatggtgcttcaatgtcgttttgtatctttaagctgtgatgttgtatatatacaatgcctcccagctagactgtaagccctttggggacaagggctgcttccagttcttggatggcgttctcctatctaccttccttcaactgctctgcatataataagcactcaataaatgctcatttgccaataaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:359 -> Molecular function: GO:0003779 [actin binding] evidence: IEA GeneID:359 -> Molecular function: GO:0005372 [water transmembrane transporter activity] evidence: IDA GeneID:359 -> Molecular function: GO:0015168 [glycerol transmembrane transporter activity] evidence: IDA GeneID:359 -> Molecular function: GO:0015250 [water channel activity] evidence: EXP GeneID:359 -> Molecular function: GO:0030165 [PDZ domain binding] evidence: IEA GeneID:359 -> Biological process: GO:0003097 [renal water transport] evidence: IEA GeneID:359 -> Biological process: GO:0006833 [water transport] evidence: IDA GeneID:359 -> Biological process: GO:0006833 [water transport] evidence: TAS GeneID:359 -> Biological process: GO:0006884 [cell volume homeostasis] evidence: IEA GeneID:359 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA GeneID:359 -> Biological process: GO:0006972 [hyperosmotic response] evidence: IEA GeneID:359 -> Biological process: GO:0007565 [female pregnancy] evidence: IEA GeneID:359 -> Biological process: GO:0007568 [aging] evidence: IEA GeneID:359 -> Biological process: GO:0007588 [excretion] evidence: TAS GeneID:359 -> Biological process: GO:0009651 [response to salt stress] evidence: IEA GeneID:359 -> Biological process: GO:0010226 [response to lithium ion] evidence: IEA GeneID:359 -> Biological process: GO:0015793 [glycerol transport] evidence: IDA GeneID:359 -> Biological process: GO:0030042 [actin filament depolymerization] evidence: IEA GeneID:359 -> Biological process: GO:0032496 [response to lipopolysaccharide] evidence: IEA GeneID:359 -> Biological process: GO:0033762 [response to glucagon stimulus] evidence: IEA GeneID:359 -> Biological process: GO:0042594 [response to starvation] evidence: IEA GeneID:359 -> Biological process: GO:0042631 [cellular response to water deprivation] evidence: IEA GeneID:359 -> Biological process: GO:0051592 [response to calcium ion] evidence: IEA GeneID:359 -> Biological process: GO:0051928 [positive regulation of calcium ion transport] evidence: IEA GeneID:359 -> Biological process: GO:0055085 [transmembrane transport] evidence: TAS GeneID:359 -> Biological process: GO:0071280 [cellular response to copper ion] evidence: IDA GeneID:359 -> Biological process: GO:0071288 [cellular response to mercury ion] evidence: IDA GeneID:359 -> Biological process: GO:0072205 [metanephric collecting duct development] evidence: IEA GeneID:359 -> Cellular component: GO:0005764 [lysosome] evidence: IEA GeneID:359 -> Cellular component: GO:0005769 [early endosome] evidence: IEA GeneID:359 -> Cellular component: GO:0005791 [rough endoplasmic reticulum] evidence: IEA GeneID:359 -> Cellular component: GO:0005794 [Golgi apparatus] evidence: IEA GeneID:359 -> Cellular component: GO:0005802 [trans-Golgi network] evidence: IEA GeneID:359 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA GeneID:359 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS GeneID:359 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA GeneID:359 -> Cellular component: GO:0016323 [basolateral plasma membrane] evidence: IEA GeneID:359 -> Cellular component: GO:0016324 [apical plasma membrane] evidence: IDA GeneID:359 -> Cellular component: GO:0016324 [apical plasma membrane] evidence: ISS GeneID:359 -> Cellular component: GO:0030136 [clathrin-coated vesicle] evidence: IEA GeneID:359 -> Cellular component: GO:0030658 [transport vesicle membrane] evidence: TAS GeneID:359 -> Cellular component: GO:0043234 [protein complex] evidence: IEA GeneID:359 -> Cellular component: GO:0055037 [recycling endosome] evidence: IEA GeneID:359 -> Cellular component: GO:0070382 [exocytic vesicle] evidence: IEA
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