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2025-05-09 17:13:57, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_182493 7998 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens myosin light chain kinase 3 (MYLK3), mRNA.
ACCESSION NM_182493
VERSION NM_182493.2 GI:146219831
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7998)
AUTHORS Al-Sadi,R., Ye,D., Dokladny,K. and Ma,T.Y.
TITLE Mechanism of IL-1beta-induced increase in intestinal epithelial
tight junction permeability
JOURNAL J. Immunol. 180 (8), 5653-5661 (2008)
PUBMED 18390750
REMARK GeneRIF: data indicate that the IL-1beta-induced increase in MLCK
protein expression and Caco-2 TJ permeability was mediated by an
increase in MLCK expression and activity and by an
NF-kappaB-dependent increase in MLCK gene transcription
REFERENCE 2 (bases 1 to 7998)
AUTHORS Chan,J.Y., Takeda,M., Briggs,L.E., Graham,M.L., Lu,J.T.,
Horikoshi,N., Weinberg,E.O., Aoki,H., Sato,N., Chien,K.R. and
Kasahara,H.
TITLE Identification of cardiac-specific myosin light chain kinase
JOURNAL Circ. Res. 102 (5), 571-580 (2008)
PUBMED 18202317
REFERENCE 3 (bases 1 to 7998)
AUTHORS Seguchi,O., Takashima,S., Yamazaki,S., Asakura,M., Asano,Y.,
Shintani,Y., Wakeno,M., Minamino,T., Kondo,H., Furukawa,H.,
Nakamaru,K., Naito,A., Takahashi,T., Ohtsuka,T., Kawakami,K.,
Isomura,T., Kitamura,S., Tomoike,H., Mochizuki,N. and Kitakaze,M.
TITLE A cardiac myosin light chain kinase regulates sarcomere assembly in
the vertebrate heart
JOURNAL J. Clin. Invest. 117 (10), 2812-2824 (2007)
PUBMED 17885681
REMARK GeneRIF: Integrated cDNA expression analysis of failing human
myocardia uncovered a novel protein kinase, cardiac-specific myosin
light chain kinase (cardiac-MLCK), which acts on MLC2v.
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AJ247087.1, DA561361.1, CR739116.1, AC007225.2 and AL691746.1.
On May 3, 2007 this sequence version replaced gi:32698825.
Summary: Phosphorylation of cardiac myosin heavy chains (see MYH7B,
MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase,
such as MYLK3, potentiates the force and rate of cross-bridge
recruitment in cardiac myocytes (Chan et al., 2008 [PubMed
18202317]).[supplied by OMIM, Jul 2008].
##Evidence-Data-START##
Transcript exon combination :: AJ247087.1, BC109096.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025082, ERS025083 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-653 AJ247087.1 1-653
654-1101 DA561361.1 122-569
1102-2668 AJ247087.1 1102-2668
2669-3146 CR739116.1 83-560
3147-7880 AC007225.2 178378-183111
7881-7998 AL691746.1 27-144 c
FEATURES Location/Qualifiers
source 1..7998
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q11.2"
gene 1..7998
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="myosin light chain kinase 3"
/db_xref="GeneID:91807"
/db_xref="HGNC:29826"
/db_xref="MIM:612147"
exon 1..593
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
misc_feature 27..29
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="upstream in-frame stop codon"
CDS 117..2576
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/EC_number="2.7.11.18"
/note="MLC kinase; cardiac-MyBP-C associated Ca/CaM
kinase; putative myosin light chain kinase 3;
cardiac-MyBP-C-associated Ca/CaM kinase; cardiac-MLCK"
/codon_start=1
/product="myosin light chain kinase 3"
/protein_id="NP_872299.2"
/db_xref="GI:146219832"
/db_xref="CCDS:CCDS10723.2"
/db_xref="GeneID:91807"
/db_xref="HGNC:29826"
/db_xref="MIM:612147"
/translation="
MSGTSKESLGHGGLPGLGKTCLTTMDTKLNMLNEKVDQLLHFQEDVTEKLQSMCRDMGHLERGLHRLEASRAPGPGGADGVPHIDTQAGWPEVLELVRAMQQDAAQHGARLEALFRMVAAVDRAIALVGATFQKSKVADFLMQGRVPWRRGSPGDSPEENKERVEEEGGKPKHVLSTSGVQSDAREPGEESQKADVLEGTAERLPPIRASGLGADPAQAVVSPGQGDGVPGPAQAFPGHLPLPTKVEAKAPETPSENLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGPTLTTEAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRAGAEPGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
"
misc_feature 1653..2426
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="Serine/Threonine protein kinases, catalytic domain;
Region: S_TKc; smart00220"
/db_xref="CDD:197582"
misc_feature 1677..2417
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="Catalytic domain of Protein Kinases; Region: PKc;
cd00180"
/db_xref="CDD:173623"
misc_feature order(1677..1691,1701..1703,1740..1742,1746..1748,
1833..1835,1881..1892,1902..1904,1908..1910,2022..2024,
2028..2030,2034..2039,2043..2045,2082..2084,2091..2093,
2136..2147)
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="active site"
/db_xref="CDD:173623"
misc_feature order(1677..1691,1701..1703,1740..1742,1746..1748,
1833..1835,1881..1892,1902..1904,2022..2024,2028..2030,
2034..2039,2043..2045,2082..2084)
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:173623"
misc_feature order(1689..1691,1902..1904,1908..1910,2022..2024,
2028..2030,2034..2036,2091..2093,2136..2147)
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:173623"
misc_feature order(2079..2099,2136..2147)
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="activation loop (A-loop); other site"
/db_xref="CDD:173623"
exon 594..684
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 685..1117
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 1118..1578
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 1579..1684
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 1685..1778
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 1779..1888
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 1889..2030
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 2031..2101
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 2102..2230
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 2231..2383
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 2384..2516
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
exon 2517..7998
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/inference="alignment:Splign:1.39.8"
variation 3147
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1645939"
misc_feature 3583..3648
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/note="GRAIL 2 excellent exon, frame 1"
STS 3753..3919
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/standard_name="G35510"
/db_xref="UniSTS:44150"
STS 3795..3883
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 4336..4963
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/standard_name="D1S1361"
/db_xref="UniSTS:149557"
STS 4521..4784
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/standard_name="L17705"
/db_xref="UniSTS:66091"
STS 4538..4878
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/standard_name="GDB:313783"
/db_xref="UniSTS:13512"
STS 4796..4905
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/standard_name="D10S275"
/db_xref="UniSTS:147992"
variation 5623
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:698417"
variation 5774
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:698416"
STS 5923..7619
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/standard_name="GDB:631802"
/db_xref="UniSTS:158429"
variation 6682
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:425556"
variation 7290
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:615366"
STS 7475..7607
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/standard_name="D7S2067E"
/db_xref="UniSTS:151120"
variation 7928..7929
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:75112486"
variation 7929
/gene="MYLK3"
/gene_synonym="caMLCK; MLCK; MLCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370159"
ORIGIN
aggagtctgtcagctacggaggacaatgaccttgcagacaccaccgcctgagtgagaaccaggggtctgtgcctctcctcattccccgctcttgcccttgtcaagcctgcaccagcatgtcaggaacctccaaggagagtctggggcatggggggctgccagggttgggcaagacctgcttaacaaccatggacacaaagctgaacatgctgaacgagaaggtggaccagctcctgcacttccaagaagatgtcacagagaagttgcagagcatgtgccgagacatgggccacctggagcggggcctgcacaggctggaggcctcccgggcaccgggcccgggcggggctgatggggttccccacattgacacccaggctgggtggcccgaggtcctggagctggtgagggccatgcagcaggatgcggcccagcacggtgccaggctggaggccctcttcaggatggtggctgcggtggacagggccatcgctttggtgggggccacgttccagaaatcaaaggtggcggatttcctcatgcaggggcgtgtgccctggaggagaggcagcccaggtgacagccctgaggagaataaagagcgagtggaagaagagggaggaaaaccaaagcatgtgctgagcaccagtggggtgcagtctgatgccagggagcctggggaagagagccagaaggcggacgtgctggaggggacagcggagaggctgccccccatcagagcgtcagggctgggagctgaccccgcccaggcagtggtctcaccgggccagggagatggtgttcctggcccagcccaggcattccctggccacctgcccctgcccacaaaggtggaagccaaggctcctgagacacccagcgagaacctcaggactggcctggaattggctccagcacccggcagggtcaatgtggtctccccgagcctggaggttgcaccaggtgcaggacaaggagcatcgtccagcaggcctgaccctgagcccttagaggaaggcacgaggctgactccagggcctggccctcagtgcccagggcctccagggctgccagcccaggccagggcaacccacagtggtggagaaacacctccaaggatctccatccacatacaagagatggatactcctggggagatgctgatgacaggcaggggcagccttggacccaccctcaccacagaggctccagcagctgcccagccaggcaagcagggcccacctgggaccgggcgctgcctccaagcccctgggactgagcccggagaacagacccctgaaggagccagagagctctccccgctgcaggagagcagcagccccgggggagtgaaggcagaggaggagcaaagggctggggccgagcctggcacgagaccaagcttggccaggagtgacgacaatgaccacgaggttggggccctgggcctgcagcagggcaaaagcccaggggcgggaaaccctgagcctgagcaggactgtgcagccagggctccggtgagagctgaagcagtaaggaggatgcccccaggcgccgaggctggcagcgtggttctggatgacagtccggccccaccagctccttttgaacaccgggtagtgagcgtcaaggagacctccatctctgcgggttacgaggtgtgccagcacgaagtcttgggagggggtcggtttggccaggtccacaggtgcacagagaagtccacaggcctcccactggctgccaagatcatcaaagtgaagagcgccaaggaccgggaggacgtgaagaacgagatcaacatcatgaaccagctcagccacgtgaacctgatccagctctatgacgccttcgagagcaagcacagctgcacccttgtcatggagtacgtggacgggggtgagctcttcgaccggatcacagatgagaagtaccacctgactgagctggatgtggtcctgttcaccaggcagatctgtgagggtgtgcattacctgcaccagcactacatcctgcacctggacctcaagccggagaacatattgtgcgtcaatcagacaggacatcaaattaagatcattgactttgggctggccagaaggtacaagcctcgagagaagctgaaggtgaacttcggcactcctgagttcctggccccagaagtcgtcaattatgagtttgtctcattccccacagacatgtggagtgtgggagtcatcacctacatgctactcagtggcttgtccccatttctaggggaaacagatgcagagaccatgaatttcattgtaaactgtagctgggattttgatgctgacacctttgaagggctctcggaggaggccaaggactttgtttcccggttgctggtcaaagagaagagctgcagaatgagtgccacacagtgcctgaaacacgagtggctgaataatttgcctgccaaagcttcaagatccaaaactcgtctcaaatcccaactactgctgcagaaatacatagctcaaagaaaatggaagaaacatttctatgtggtgactgctgccaacaggttaaggaaatttccaacttctccctaatcttcaactctgctgctccaatgggtccagaaattactgaggccagtggtgaagtgaagagatgactcaaacatttaaataatttggctttttggtattattgattccacttattttgtaaaaatggttatggctgctgccttccttgtggatgaaaagtggctgtaaagaagcttcctaagaacgtttttttctgccttgtaagatcactacgtgtgaaatgctctgagtacctttcaaatatacctacttttggtggtaagtgtagggatgctttaggtaggtactttgcatctgtcgaatttaaattctaaactcacactgattaaggaactcagtagactactttgcaggggccatgttattcagtgttatctcctccagtacaaagaattcctagaattttgatttgctcaggtgtgagctgacattttattgtactaccccattcttgtgttaagccatgtggatttaggacagtgatcttcaaacttgctttaacttatgctcccttttgagaatcagcatcacttgaaatgtcaaaatatgtcaactctcatagccaaatcaaagaagtgatcattttgactgtgctttttaaatctccacacacctccacctctctcctaattctgcctgtcttaacccctctgtcttagttataaatttctggtcttgtaagtctggaagctgataggcaatttatgaaagagataagaatgtaatgaggttccgctttctgagaaacacagaaatgatacatcctgagacataaaggaaagctgctcttctgctgcctcaggctgtagcactctcaatgttgtcactctacacatacactttctatatacatgtacagttgacccttgaacagggtttgaattgcagtcaacttaaatgtggattttctttcacctttgtcacccctgagacagcaacaccatgctctcctcttcatcccactctgcagcctactcaacaggaagatgatgaagatgaacacctttatgatgatccactttcacttaatgaatagtaaacatatgttttcctccttatgattttagtaacttttctctagcttactttattgtaagaatacagtatataagctgggtgtggtggctcatgcccataatcccagcactttgggaggctgaggcaggcagatcacttgaggtcaggagttcaagaccagcctggccaacacagtgaaaccccatctctactaaaaatacaaaaattagtggggcgtggtggcggatgcctgtaatgtcagctactctggaggctgaggcaggagaactgcttgaacctgggaggtggagtttgcagtgagccaagattgcaccactgcactccagcctaggcaacagagcaagactccgtctcaaaaaaaaaaaaaaaaaagaatacagtatatgtatatatacacacacacaaacacacacacacacgaacacatatgtgtgtatgggtattaactgactgtttatattattgatagggcttccagtcaacattaggctattagtagttaagtttttggggagacaaaagttatactcagattttctactgcaagggggtaggcactcctaaccctcacattgttcaagggtccactgtacatttaaacacttttctatatgcattagagtagccctgtcatcccttcactgaaatcatactgttctcaacatggcaagcaactaacacttttttttttttttgagacagggtctcactctgttgcccaggctgcagtgcagtggtgtgatcttggctcactgtagcctccgcctcctgggctcaggcgatcatgagtacctgggaccataggtgcccgctactacacccagctaatttttgtatttttagtggagatagggttttgccatgttgcccaacctggtcttgagctcaagcgatccacctgccccagcctcccaaagtgctgggattataggtgtgagccaccacacccagcttcaactaacacatttacgaacttgtatacatgtatatttagatactttaccaacttgtaaaatggttaaaggagtactttattatgaaaaaatatacaatctttaaaatttccttacttctacatgatttttgtgctattcccatttttttcctcaggtgagcagctttagttttttattttttttgagagagtcttcctctgtcacccaggctggagtgcactggtgtgttcttggctcactgcaacctctgcctcccgggttcaagtgatcttgtgcctcagcctcccaggtagctgggattacaggcgtgtgctgccacgcccagctaatttttgtatttttggtagagatggggttttgccatgttggccaggctggtctcgaactcctgacctcagatgatccacctgtcttggcctcccaaagagctgggaatataggcatgagccactgtgcttggcctcaggtgagcagctttagtcaatgttgtgaattttagattttaattagacatgcaacagtttcactacctttcaggatttttgtcctgtaacagaggctcttgctttttgacagagaggtaggcaggtggagaggttatcctgctgctgcagttctcaagttgttaagtttcctctggaaggctaacccttgttgggaactaacagtttcaataccagcaagtctaggcctgctccaagttggtcagctgaagaatgaacatcagaagacacagctgctgaaagttgtcctttgatgagacagtgatagtgatttggtaaaatgtcttattttttaaatgtcagttatctttctttaaaaggttttttgagggcagcctccagaaggagctagagagtatattttatagttctattgtggttcataccctgttttcgacttaagattctggagaatgctatgaaacatctccccagaaaaagacagttaattaccatatctagagcagcactgcccaacaaaaatatagtacaggctatacacataattaaaacatttctagtagcttctctaacaaaacccattgaaagccaattttaataatttatataacttagtgtatcaaaaatatttcaatatgtaatcaacataaaattgagatactttaccagctactagggaggctgaggccagagaatcacttgaacccagggggtggaggttgcagtgagccaagatcacaccattgaactccagcctgggcaacaagagcaaaactccgtctcaaaaaaaaagagatattttatattctttttctcatactaagtctcaaaaatctggtatattttacacttaaaaacacatgtcaaggctaggcatggtggctcacatctgtaatcccagcactttgggaggccaaggtgggcagattgctggccaacatggtaaaaccccatctctaaaaatataaaaattagctgggcgtggtggcgcatacctgtaatcccagctacttgggaggctaaggcacaagaatcacttaaacaggaggcaggggttgcagtgagctgagatcacaccactgcactccagcctgggtggcagagcaaaactttgtccccacccctgacaaaaaacaaacaaacaaacaaaacaaaaaaaaacctgtcaattcagatgctaggttttcatcagacgtacttaatctgtatttagatttcttaaaacttactgtggaaaatgtatttacatactcaagttgtttgaaacataactcactgttttccaataactgaagtatccacttttacatgtattaaaattaaataaaattagaaattcagttctgcagttgcactagccacattttaagtgtttaatagccacacgtggttagtggcatctatattggacagggcagatctagagagaatcctgtatctaacaattttaatttttttccctttatgctgttattccttacctagagaaacaatttccctccaaagttcctttgaggggtctgtttaggccaggccaacacaagtgacctatgtggattttagcatcctttttttgaaatttgaggttttatgaagcttgagtttttctggatatttttagtaatttgctggtgtgtacttagctcaaatacttgattgcaactgtgttgggtcaactatttctaatgggacttttccatttgcatgtacagtcactggaaactgctgggcagagaaactctaaaaggtagttggggcacactttttccacctgtcagattggtgaagaattggtgaggctgtggggaaaatggcattctcccacttttgatggatatgtatccaaataaaagtcattcccatgctttctttcatccagaaattttatttctagaaatttatccctccgtacttgaacaattgtatagagatttattcaaaatgatgtttactatagcactgttgctaatggcccagtaaaaacaaccaacacatgcctattagtttggttttagttaaatgaattttgccacatccatgtagtggaatacctcacagctgttatagatagatctagatatactgaaagccattttttcttaaattatagaatgtatatatggtatcatcccatttgtgaagagacatatgcttatatgtgcattaaaaaaccgtaggatatgcaagaaacttaacagtggagtgtgaaaagtgggtgattgggagagggggaattccacttttcatttatctttctgaaccttttgaatcttttttttttttttttttacaatgagcatgtattcctttttttttttttctttccaagatggagtctcactctgttgccaggctggagtgcagtggcgcaatcttggcttactgcaacatccacctcccgagttcaagtgatttctcctgcctcagcctcccaagtagctgggactacaggcatgcgccaccacgcccagctaatttttgtgtttttagtagagatgggctttcaccatgctggccaggatggtctcgatctcttgacctcgtgatctgcccacctcggcctcccaaagtgctgggattacaggtgtgagccactgcgcctggcccgcatgtattacatttataattaaaaattcacaactcaatgtcaagtgtgaaccttgtgttgaccctgatttgagcaagcaataaaaagatatttttgagacatttagattatgaatttcacatttgatgatagttactattaattttgtgaggtgtgatattggcaatgtggttagatgacttcagagaaaaaggaaggtatagttaagcaagtatggcaacatctaataacttgggtctaggtgatgtgtatgggtttcattatactgtcctctttactgttgtatgtatttgaaaacattcatgacaaaaaaactttttaatcagttaaataaaccatgaagaacggttaaagaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:91807 -> Molecular function: GO:0004683 [calmodulin-dependent protein kinase activity] evidence: ISS
GeneID:91807 -> Molecular function: GO:0004687 [myosin light chain kinase activity] evidence: ISS
GeneID:91807 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:91807 -> Biological process: GO:0002528 [regulation of vascular permeability involved in acute inflammatory response] evidence: IMP
GeneID:91807 -> Biological process: GO:0006468 [protein phosphorylation] evidence: ISS
GeneID:91807 -> Biological process: GO:0045214 [sarcomere organization] evidence: ISS
GeneID:91807 -> Biological process: GO:0048769 [sarcomerogenesis] evidence: ISS
GeneID:91807 -> Biological process: GO:0055003 [cardiac myofibril assembly] evidence: ISS
GeneID:91807 -> Biological process: GO:0060298 [positive regulation of sarcomere organization] evidence: ISS
GeneID:91807 -> Biological process: GO:0071347 [cellular response to interleukin-1] evidence: IMP
GeneID:91807 -> Cellular component: GO:0005737 [cytoplasm] evidence: ISS
GeneID:91807 -> Cellular component: GO:0005829 [cytosol] evidence: ISS
GeneID:91807 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_872299 -> EC 2.7.11.18
by
@meso_cacase at
DBCLS
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