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2025-05-09 16:53:02, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_024786 2618 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens zinc finger, DHHC-type containing 11 (ZDHHC11), mRNA.
ACCESSION NM_024786 XM_940764
VERSION NM_024786.2 GI:196162714
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2618)
AUTHORS Yamamoto,Y., Chochi,Y., Matsuyama,H., Eguchi,S., Kawauchi,S.,
Furuya,T., Oga,A., Kang,J.J., Naito,K. and Sasaki,K.
TITLE Gain of 5p15.33 is associated with progression of bladder cancer
JOURNAL Oncology 72 (1-2), 132-138 (2007)
PUBMED 18025801
REMARK GeneRIF: data suggest that gain of 5p15.33 (TPPP and ZDHHC11) may
become a potential biomarker identifying high-risk patients with
disease progression in bladder cancer.
REFERENCE 2 (bases 1 to 2618)
AUTHORS Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
TITLE The secreted protein discovery initiative (SPDI), a large-scale
effort to identify novel human secreted and transmembrane proteins:
a bioinformatics assessment
JOURNAL Genome Res. 13 (10), 2265-2270 (2003)
PUBMED 12975309
REMARK Erratum:[Genome Res. 2003 Dec;13(12):2759]
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AK023215.1, AK024233.1 and BC032000.1.
On Aug 15, 2008 this sequence version replaced gi:13376149.
##Evidence-Data-START##
Transcript exon combination :: AK023215.1, BC032000.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-2261 AK023215.1 1-2261
2262-2296 AK024233.1 3580-3614
2297-2604 AK023215.1 2316-2623
2605-2618 BC032000.1 2243-2256
FEATURES Location/Qualifiers
source 1..2618
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5p15.33"
gene 1..2618
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/note="zinc finger, DHHC-type containing 11"
/db_xref="GeneID:79844"
/db_xref="HGNC:19158"
/db_xref="HPRD:15708"
exon 1..606
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
variation 35
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="g"
/replace="t"
/db_xref="dbSNP:3747732"
variation 56
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:3747733"
misc_feature 58..60
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/note="upstream in-frame stop codon"
variation 100
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:3747734"
variation 102..103
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace=""
/replace="aggcctggccaggtcctctgcccagg"
/db_xref="dbSNP:3833451"
CDS 385..1623
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/note="zinc finger, DHHC domain containing 11; DHHC-11;
zinc finger protein 399; zinc finger DHHC
domain-containing protein 11"
/codon_start=1
/product="probable palmitoyltransferase ZDHHC11"
/protein_id="NP_079062.1"
/db_xref="GI:13376150"
/db_xref="CCDS:CCDS3857.1"
/db_xref="GeneID:79844"
/db_xref="HGNC:19158"
/db_xref="HPRD:15708"
/translation="
MDTRSGSQCSVTPEAILNNEKLVLPPRISRVNGWSLPLHYFQVVTWAVFVGLSSATFGIFIPFLPHAWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVNKKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPGVLRTDPRYEDVKNMNTWLLFLPLFPVQVQTLIVVIIGMLVLLLDFLGLVHLGQLLIFHIYLKAKKMTTFEYLINNRKEESSKHQAVRKDPYVQMDKGVLQQGAGALGSSAQGVKAKSSLLIHKHLCHFCTSVNQDGDSTAREGDEDPCPSALGAKARNSRLICRRLCQFSTRVHPDGGSMAQEADDAPSISTLGLQQETTEPMKTDSAESED
"
misc_feature 511..573
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H8X9.1);
transmembrane region"
misc_feature 592..654
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H8X9.1);
transmembrane region"
misc_feature 634..1209
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/note="DHHC palmitoyltransferase; Region: zf-DHHC;
pfam01529"
/db_xref="CDD:201843"
misc_feature 913..975
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H8X9.1);
transmembrane region"
misc_feature 1075..1137
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H8X9.1);
transmembrane region"
exon 607..785
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
exon 786..887
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
exon 888..1012
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
variation 1004
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="g"
/replace="t"
/db_xref="dbSNP:3863148"
exon 1013..1168
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
exon 1169..1284
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
exon 1285..1319
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
exon 1320..1407
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
variation 1348
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:2335582"
variation 1353
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="g"
/db_xref="dbSNP:2878465"
variation 1354
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:2878466"
variation 1355
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="g"
/db_xref="dbSNP:2878467"
variation 1357
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:2335583"
variation 1358
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:2878468"
variation 1389
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:1808545"
variation 1400
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="c"
/db_xref="dbSNP:2335585"
exon 1408..1442
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
exon 1443..1530
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
variation 1499
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="g"
/db_xref="dbSNP:3747738"
exon 1531..1565
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
exon 1566..1630
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
exon 1631..2606
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/inference="alignment:Splign:1.39.8"
STS 1688..1887
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/standard_name="A008P27"
/db_xref="UniSTS:55169"
variation 2030
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="g"
/db_xref="dbSNP:453637"
variation 2297
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="c"
/db_xref="dbSNP:3180297"
variation 2318
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1057004"
variation 2334
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="g"
/replace="t"
/db_xref="dbSNP:1057005"
variation 2340
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:1057006"
variation 2341
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:1057007"
variation 2357
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="g"
/replace="t"
/db_xref="dbSNP:1057008"
variation 2365
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="t"
/db_xref="dbSNP:1057009"
variation 2379
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="a"
/replace="g"
/db_xref="dbSNP:1057010"
variation 2393
/gene="ZDHHC11"
/gene_synonym="ZNF399"
/replace="c"
/replace="g"
/db_xref="dbSNP:1057011"
ORIGIN
gtgaacgggttgtgggacctgtcgctgtgtgggggctgtcgagcactccccagaacgtaacaaatcctcaggggaactgatgggcggtcgcgcgggcactgggtcctccacaccctggagagccgttttccgttgccactcggctctggccggggtcacattctgcagcatgtctgttcattcccctgggcggggccctgcaccgactccagcccagcccctgctccctctgcggggaacgtggccccaggcagtgctgggccattggctgtcagtgctggtcctggcggctgcattcccagtccccttggtctctgtgacagtgggcggggccggccctcccaggatctgacggcgcaggtcctccccttctgtgtcctgcagatggacacccgctccgggagccagtgttccgtcaccccagaagccatactcaataatgaaaagctggtcttgccgccccgcatctccagagtgaacggctggtcgttacccctgcactacttccaggtggtgacctgggctgtcttcgtgggcctttcctcggccaccttcgggatcttcattcccttcctgcctcacgcgtggaaatacattgcctacgtggtgaccggggggatcttctcgttccacctcgtcgtccacctgatcgcgtcctgcatcgacccggccgactccaatgtcagactcatgaagaactattctcagcccatgcccctcttcgacagatcaaaacatgcacacgtgatccagaatcagttctgccacctgtgcaaggtcaccgtgaacaagaaaaccaaacactgcatttcctgcaataagtgtgtgtccggcttcgaccaccactgcaaatggatcaacaactgcgtgggaagccggaattattggttcttcttcagcactgtggcctcggccacagctggcatgctctgcctgatcgccatcctgctgtatgtcctcgtccagtacctcgtgaaccccggggtgctccgcacggaccccaggtatgaagatgtcaagaatatgaacacgtggctgctgttcctccccctgttcccggtgcaggtgcagaccctgatagtcgtgatcatcgggatgctcgtgctcctgctggactttcttggcttggtgcacctgggccagctgctcatcttccacatctacctgaaggccaagaagatgaccacctttgagtatctcattaataaccgcaaagaagagagttcaaaacatcaagcagtgaggaaagatccatacgtgcaaatggacaaaggagttctccagcaaggagctggcgccctgggctcatctgcacagggagtcaaagccaagagctccctgctgattcacaagcacttatgtcacttctgcacttcagtaaaccaggatggggattcgacggcacgggaaggggatgaagacccgtgtccatctgcacttggagccaaggccaggaactcccggctgatttgcaggcgcctgtgtcagttctccactcgtgtacacccagacgggggctcgatggcacaggaagcagatgatgccccgagtatatctacacttgggctgcaacaagaaacaacagagcccatgaaaactgacagtgctgaaagtgaagactgagattcaggagctcaggtgcccctgtgatccaggtcttctaccctgaaaccccaccctccatcaaggtcctgcctgtagagtctaccttgcaaagcctcctgctcctacccatgctacaggccaggaaccagagcccatcatctcagaggcccctggatgtccttcgaaggaaccaggaccctcagagcccagcatccatctctgtcatcatcttcatcacacccaaagaagagccagccttgcaggagggtttacatctccaggaagatgggctgccagcaactgcagaggatgcagccacctgcttaactgtgctgtccagccagccagccagctgcagggcctcttgctgcttaagagctgatgggccgggcatgttggctcacacctgtgagcacagtactgggaaatgggagcacagtactaggaaatgggagcacagtactgggaaatgggagcacagtactgggaaatgggggctcacagcactgcaaaatgggagcacagtattgggaaatgggagcacagtactgggaagtgggagcacagtactgagaagtgggagcacagtactgagaaatgggagtacactactgagaaatgggagcacagtactgggaaatgggcatacagtactgagaaatgggagcacacagtactgggaaatgggagcacagtactgggaaatgggagcccacagtactgggaaaggggagttcacagtactcggaaatgggagcatagtactgggaaatgggagcacagtactgggaaatgggagcatagtactgggaaaccccagacctggattctgagtttttcagcctagcccagacttcttatcttagtagacaaaaagagtcaataccagagaaccagaggcatcctctgtattttaatgaactctgcattttaatctgtttagtagtcattttttaaaagataatcagttttccaaatatatctataagttactacgtgcaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:79844 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
GeneID:79844 -> Molecular function: GO:0016746 [transferase activity, transferring acyl groups] evidence: IEA
GeneID:79844 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
by
@meso_cacase at
DBCLS
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