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2025-05-09 16:39:16, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_016232 2058 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens interleukin 1 receptor-like 1 (IL1RL1), transcript
variant 1, mRNA.
ACCESSION NM_016232
VERSION NM_016232.4 GI:27894323
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2058)
AUTHORS Chen,L.Q., de Lemos,J.A., Das,S.R., Ayers,C.R. and Rohatgi,A.
TITLE Soluble ST2 is associated with all-cause and cardiovascular
mortality in a population-based cohort: the Dallas Heart Study
JOURNAL Clin. Chem. 59 (3), 536-546 (2013)
PUBMED 23220272
REMARK GeneRIF: Soluble ST2 is associated with all-cause and
cardiovascular mortality in a population-based cohort.
REFERENCE 2 (bases 1 to 2058)
AUTHORS Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee
JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K,
Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z,
Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN,
Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A,
Boucher G, Brand S, Buning C, Cohain A, Cichon S, D'Amato M, De
Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson
LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas
J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH,
Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees
CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W,
Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M,
Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber
S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M,
Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier
RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, Silverberg MS, Annese V,
Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD,
Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC and
Cho JH.
CONSRTM International IBD Genetics Consortium (IIBDGC)
TITLE Host-microbe interactions have shaped the genetic architecture of
inflammatory bowel disease
JOURNAL Nature 491 (7422), 119-124 (2012)
PUBMED 23128233
REFERENCE 3 (bases 1 to 2058)
AUTHORS Hirota,T., Takahashi,A., Kubo,M., Tsunoda,T., Tomita,K.,
Sakashita,M., Yamada,T., Fujieda,S., Tanaka,S., Doi,S.,
Miyatake,A., Enomoto,T., Nishiyama,C., Nakano,N., Maeda,K.,
Okumura,K., Ogawa,H., Ikeda,S., Noguchi,E., Sakamoto,T., Hizawa,N.,
Ebe,K., Saeki,H., Sasaki,T., Ebihara,T., Amagai,M., Takeuchi,S.,
Furue,M., Nakamura,Y. and Tamari,M.
TITLE Genome-wide association study identifies eight new susceptibility
loci for atopic dermatitis in the Japanese population
JOURNAL Nat. Genet. 44 (11), 1222-1226 (2012)
PUBMED 23042114
REFERENCE 4 (bases 1 to 2058)
AUTHORS Salker,M.S., Nautiyal,J., Steel,J.H., Webster,Z., Sucurovic,S.,
Nicou,M., Singh,Y., Lucas,E.S., Murakami,K., Chan,Y.W., James,S.,
Abdallah,Y., Christian,M., Croy,B.A., Mulac-Jericevic,B., Quenby,S.
and Brosens,J.J.
TITLE Disordered IL-33/ST2 activation in decidualizing stromal cells
prolongs uterine receptivity in women with recurrent pregnancy loss
JOURNAL PLoS ONE 7 (12), E52252 (2012)
PUBMED 23300625
REMARK GeneRIF: Il-33/ST2 activation in HESCS drives an autoinflammatory
response that controls the temporal expression of receptivity genes
REFERENCE 5 (bases 1 to 2058)
AUTHORS Ramasamy A, Kuokkanen M, Vedantam S, Gajdos ZK, Couto Alves A, Lyon
HN, Ferreira MA, Strachan DP, Zhao JH, Abramson MJ, Brown MA, Coin
L, Dharmage SC, Duffy DL, Haahtela T, Heath AC, Janson C, Kahonen
M, Khaw KT, Laitinen J, Le Souef P, Lehtimaki T, Madden PA, Marks
GB, Martin NG, Matheson MC, Palmer CD, Palotie A, Pouta A,
Robertson CF, Viikari J, Widen E, Wjst M, Jarvis DL, Montgomery GW,
Thompson PJ, Wareham N, Eriksson J, Jousilahti P, Laitinen T,
Pekkanen J, Raitakari OT, O'Connor GT, Salomaa V, Jarvelin MR and
Hirschhorn JN.
CONSRTM Australian Asthma Genetics Consortium Collaborators
TITLE Genome-wide association studies of asthma in population-based
cohorts confirm known and suggested loci and identify an additional
association near HLA
JOURNAL PLoS ONE 7 (9), E44008 (2012)
PUBMED 23028483
REFERENCE 6 (bases 1 to 2058)
AUTHORS Lohning,M., Stroehmann,A., Coyle,A.J., Grogan,J.L., Lin,S.,
Gutierrez-Ramos,J.C., Levinson,D., Radbruch,A. and Kamradt,T.
TITLE T1/ST2 is preferentially expressed on murine Th2 cells, independent
of interleukin 4, interleukin 5, and interleukin 10, and important
for Th2 effector function
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (12), 6930-6935 (1998)
PUBMED 9618516
REFERENCE 7 (bases 1 to 2058)
AUTHORS Kumar,S., Tzimas,M.N., Griswold,D.E. and Young,P.R.
TITLE Expression of ST2, an interleukin-1 receptor homologue, is induced
by proinflammatory stimuli
JOURNAL Biochem. Biophys. Res. Commun. 235 (3), 474-478 (1997)
PUBMED 9207179
REFERENCE 8 (bases 1 to 2058)
AUTHORS Yanagisawa,K., Naito,Y., Kuroiwa,K., Arai,T., Furukawa,Y.,
Tomizuka,H., Miura,Y., Kasahara,T., Tetsuka,T. and Tominaga,S.
TITLE The expression of ST2 gene in helper T cells and the binding of ST2
protein to myeloma-derived RPMI8226 cells
JOURNAL J. Biochem. 121 (1), 95-103 (1997)
PUBMED 9058198
REFERENCE 9 (bases 1 to 2058)
AUTHORS Gayle,M.A., Slack,J.L., Bonnert,T.P., Renshaw,B.R., Sonoda,G.,
Taguchi,T., Testa,J.R., Dower,S.K. and Sims,J.E.
TITLE Cloning of a putative ligand for the T1/ST2 receptor
JOURNAL J. Biol. Chem. 271 (10), 5784-5789 (1996)
PUBMED 8621446
REFERENCE 10 (bases 1 to 2058)
AUTHORS Tominaga,S., Yokota,T., Yanagisawa,K., Tsukamoto,T., Takagi,T. and
Tetsuka,T.
TITLE Nucleotide sequence of a complementary DNA for human ST2
JOURNAL Biochim. Biophys. Acta 1171 (2), 215-218 (1992)
PUBMED 1482686
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AB012701.3.
On Jan 24, 2003 this sequence version replaced gi:24475649.
Summary: The protein encoded by this gene is a member of the
interleukin 1 receptor family. Studies of the similar gene in mouse
suggested that this receptor can be induced by proinflammatory
stimuli, and may be involved in the function of helper T cells.
This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1
receptor, type II (IL1R2) and interleukin 1 receptor-like 2
(IL1RL2) form a cytokine receptor gene cluster in a region mapped
to chromosome 2q12. Alternative splicing of this gene results in
multiple transcript variants. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (1) encodes the longest isoform
(1).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AB012701.3 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025098 [ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..2058
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q12"
gene 1..2058
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/note="interleukin 1 receptor-like 1"
/db_xref="GeneID:9173"
/db_xref="HGNC:5998"
/db_xref="HPRD:03123"
/db_xref="MIM:601203"
exon 1..122
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 102
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:184386656"
variation 113
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace=""
/replace="c"
/db_xref="dbSNP:57065265"
exon 123..332
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 200
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:13431828"
variation 201
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77378267"
variation 210
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:370403265"
misc_feature 257..259
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/note="upstream in-frame stop codon"
variation 260
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:372016897"
CDS 272..1942
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/note="isoform 1 precursor is encoded by transcript
variant 1; homolog of mouse growth stimulation-expressed;
interleukin 1 receptor-related protein; interleukin-1
receptor-like 1"
/codon_start=1
/product="interleukin-1 receptor-like 1 isoform 1
precursor"
/protein_id="NP_057316.3"
/db_xref="GI:27894324"
/db_xref="CCDS:CCDS2057.1"
/db_xref="GeneID:9173"
/db_xref="HGNC:5998"
/db_xref="HPRD:03123"
/db_xref="MIM:601203"
/translation="
MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMPVPSKIPRKASSLTPLAAQKQ
"
sig_peptide 272..325
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
misc_feature 317..583
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/note="First immunoglobulin (Ig)-like domain of
interleukin-1 receptor (IL1R) and similar proteins;
Region: Ig1_IL1R_like; cd05756"
/db_xref="CDD:143233"
misc_feature order(323..325,329..346)
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/note="antagonist binding site; other site"
/db_xref="CDD:143233"
mat_peptide 326..1939
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/product="interleukin-1 receptor-like 1 isoform 1"
misc_feature 533..535
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/experiment="experimental evidence, no additional details
recorded"
/note="acetylation site"
misc_feature 623..883
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/note="Second immunoglobulin (Ig)-like domain of
interleukin-1 receptor (IL1R) and similar proteins;
Region: Ig2_IL1R_like; cd05757"
/db_xref="CDD:143234"
misc_feature order(623..628,632..643,659..661,674..676,680..682,
764..766,878..880)
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/note="antagonist binding site; other site"
/db_xref="CDD:143234"
misc_feature 1256..1318
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01638.4);
transmembrane region"
misc_feature 1463..1870
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/note="TIR domain; Region: TIR; pfam01582"
/db_xref="CDD:201870"
variation 290
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="g"
/replace="t"
/db_xref="dbSNP:142516188"
variation 291
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201837678"
variation 298
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:115399106"
variation 310
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200098412"
variation 324
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376279073"
exon 333..543
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 376
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144435600"
variation 380
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146539272"
variation 406
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:190188722"
variation 407
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:182781591"
variation 410
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201523855"
variation 415
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="g"
/db_xref="dbSNP:147316935"
variation 444
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:140931129"
variation 449
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146872465"
variation 455
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:375754947"
variation 461
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:202037442"
variation 504
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:1041973"
variation 509
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200028993"
variation 510
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:34210856"
variation 528
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:145568700"
variation 531
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369779260"
exon 544..718
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 570
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141061248"
variation 577
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="g"
/db_xref="dbSNP:148229923"
variation 584
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200221077"
variation 586
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:111382791"
variation 593
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199800154"
variation 638
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:371207219"
variation 640
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:140675864"
variation 655
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:376294785"
variation 670
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="g"
/replace="t"
/db_xref="dbSNP:149494752"
variation 678
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:143378674"
variation 699
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367674419"
variation 701
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141010284"
variation 718
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200484415"
exon 719..881
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 729
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:114797672"
variation 754
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142878092"
variation 757
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:189627011"
variation 796
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200131845"
variation 797
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:34225180"
variation 808
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368736748"
variation 810
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141101455"
variation 837
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="g"
/replace="t"
/db_xref="dbSNP:148867750"
variation 847
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112336397"
variation 855
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201973706"
variation 858
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200831341"
variation 862
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:368468978"
variation 867
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368053458"
variation 872
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:137964169"
variation 873
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:143458919"
variation 874
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="g"
/replace="t"
/db_xref="dbSNP:201621624"
variation 875
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201365371"
exon 882..953
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 914
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:75320001"
variation 917
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111970215"
variation 921
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:188504053"
variation 923
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373122141"
exon 954..1095
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 962
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:75779188"
variation 1015
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:150894779"
variation 1016
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:146105446"
variation 1018
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:372957266"
variation 1023
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="g"
/db_xref="dbSNP:140073514"
exon 1096..1241
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 1129
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199635856"
variation 1144
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:35298562"
variation 1157
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="g"
/replace="t"
/db_xref="dbSNP:146406137"
variation 1161
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:140301260"
variation 1162
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:373664545"
variation 1175
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150347157"
variation 1200
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="g"
/db_xref="dbSNP:368714053"
variation 1216
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:372391703"
variation 1231
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:202062299"
exon 1242..1388
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 1248
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:180959006"
variation 1251
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369104980"
variation 1256
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112595294"
variation 1257
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:185314669"
variation 1301
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367848630"
variation 1311
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:188567206"
variation 1326
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:369445462"
variation 1327
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:116272080"
variation 1336
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:148165655"
variation 1370
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201256810"
exon 1389..1556
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 1418
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="g"
/replace="t"
/db_xref="dbSNP:376977990"
variation 1422
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200610115"
variation 1424
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:187567035"
variation 1425
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:190651658"
variation 1443
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146118394"
variation 1457
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200737120"
variation 1458
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138892317"
variation 1461
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139260265"
variation 1500
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:373904303"
variation 1503
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:149971818"
variation 1518
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:148477219"
variation 1526
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201555383"
variation 1528
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:370672033"
variation 1536
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199998092"
exon 1557..2058
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/inference="alignment:Splign:1.39.8"
variation 1568
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:4988956"
variation 1579
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:151156973"
variation 1580
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:367543539"
variation 1582
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200442848"
variation 1587
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150294315"
variation 1594
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201145282"
variation 1598
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:145147690"
variation 1600
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111942110"
variation 1636
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:4988957"
variation 1651
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112596146"
variation 1669
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371424721"
variation 1676
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:114130235"
variation 1685
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:145303895"
variation 1690
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:73004242"
variation 1720
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="g"
/db_xref="dbSNP:151022743"
variation 1730
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372144350"
variation 1772
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="c"
/db_xref="dbSNP:10192036"
variation 1773
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:10204137"
variation 1792
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="g"
/replace="t"
/db_xref="dbSNP:138992262"
variation 1794
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201612691"
variation 1804
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:113360315"
variation 1819
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:181315872"
variation 1827
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="t"
/db_xref="dbSNP:149593692"
variation 1840
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369745219"
variation 1846
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:4988958"
variation 1862
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373778810"
variation 1917
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:10192157"
variation 1923
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:10206753"
variation 1951
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="g"
/replace="t"
/db_xref="dbSNP:367840654"
variation 1979
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371673572"
variation 1996
/gene="IL1RL1"
/gene_synonym="DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367576518"
ORIGIN
aaagagaggctggctgttgtatttagtaaagctataaagctgtaagagaaattggctttctgagttgtgaaactgtgggcagaaagttgaggaagaaagaactcaagtacaacccaatgaggttgagatataggctactcttcccaactcagtcttgaagagtatcaccaactgcctcatgtgtggtgaccttcactgtcgtatgccagtgactcatctggagtaatctcaacaacgagttaccaatacttgctcttgattgataaacagaatggggttttggatcttagcaattctcacaattctcatgtattccacagcagcaaagtttagtaaacaatcatggggcctggaaaatgaggctttaattgtaagatgtcctagacaaggaaaacctagttacaccgtggattggtattactcacaaacaaacaaaagtattcccactcaggaaagaaatcgtgtgtttgcctcaggccaacttctgaagtttctaccagctgcagttgctgattctggtatttatacctgtattgtcagaagtcccacattcaataggactggatatgcgaatgtcaccatatataaaaaacaatcagattgcaatgttccagattatttgatgtattcaacagtatctggatcagaaaaaaattccaaaatttattgtcctaccattgacctctacaactggacagcacctcttgagtggtttaagaattgtcaggctcttcaaggatcaaggtacagggcgcacaagtcatttttggtcattgataatgtgatgactgaggacgcaggtgattacacctgtaaatttatacacaatgaaaatggagccaattatagtgtgacggcgaccaggtccttcacggtcaaggatgagcaaggcttttctctgtttccagtaatcggagcccctgcacaaaatgaaataaaggaagtggaaattggaaaaaacgcaaacctaacttgctctgcttgttttggaaaaggcactcagttcttggctgccgtcctgtggcagcttaatggaacaaaaattacagactttggtgaaccaagaattcaacaagaggaagggcaaaatcaaagtttcagcaatgggctggcttgtctagacatggttttaagaatagctgacgtgaaggaagaggatttattgctgcagtacgactgtctggccctgaatttgcatggcttgagaaggcacaccgtaagactaagtaggaaaaatccaattgatcatcatagcatctactgcataattgcagtatgtagtgtatttttaatgctaatcaatgtcctggttatcatcctaaaaatgttctggattgaggccactctgctctggagagacatagctaaaccttacaagactaggaatgatggaaagctctatgatgcttatgttgtctacccacggaactacaaatccagtacagatggggccagtcgtgtagagcactttgttcaccagattctgcctgatgttcttgaaaataaatgtggctataccttatgcatttatgggagagatatgctacctggagaagatgtagtcactgcagtggaaaccaacatacgaaagagcaggcggcacattttcatcctgacccctcagatcactcacaataaggagtttgcctacgagcaggaggttgccctgcactgtgccctcatccagaacgacgccaaggtgatacttattgagatggaggctctgagcgagctggacatgctgcaggctgaggcgcttcaggactccctccagcatcttatgaaagtacaggggaccatcaagtggagggaggaccacattgccaataaaaggtccctgaattctaaattctggaagcacgtgaggtaccaaatgcctgtgccaagcaaaattcccagaaaggcctctagtttgactcccttggctgcccagaagcaatagtgcctgctgtgatgtgcaaaggcatctgagtttgaagctttcctgacttctcctagctggcttatgcccctgcactgaagtgtgaggagcaggaatattaaagggattcaggcctc
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9173 -> Molecular function: GO:0002113 [interleukin-33 binding] evidence: IEA
GeneID:9173 -> Molecular function: GO:0002114 [interleukin-33 receptor activity] evidence: IEA
GeneID:9173 -> Molecular function: GO:0004896 [cytokine receptor activity] evidence: TAS
GeneID:9173 -> Molecular function: GO:0004908 [interleukin-1 receptor activity] evidence: IEA
GeneID:9173 -> Molecular function: GO:0005057 [receptor signaling protein activity] evidence: TAS
GeneID:9173 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:9173 -> Biological process: GO:0002826 [negative regulation of T-helper 1 type immune response] evidence: IEA
GeneID:9173 -> Biological process: GO:0006955 [immune response] evidence: NAS
GeneID:9173 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
GeneID:9173 -> Biological process: GO:0032689 [negative regulation of interferon-gamma production] evidence: IEA
GeneID:9173 -> Biological process: GO:0032754 [positive regulation of interleukin-5 production] evidence: IEA
GeneID:9173 -> Biological process: GO:0043032 [positive regulation of macrophage activation] evidence: IEA
GeneID:9173 -> Biological process: GO:0043124 [negative regulation of I-kappaB kinase/NF-kappaB cascade] evidence: IEA
GeneID:9173 -> Biological process: GO:0050729 [positive regulation of inflammatory response] evidence: IEA
GeneID:9173 -> Biological process: GO:0090197 [positive regulation of chemokine secretion] evidence: IEA
GeneID:9173 -> Cellular component: GO:0005576 [extracellular region] evidence: IEA
GeneID:9173 -> Cellular component: GO:0009897 [external side of plasma membrane] evidence: IEA
GeneID:9173 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
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