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2025-05-09 16:28:04, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_006446 2800 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens solute carrier organic anion transporter family,
member 1B1 (SLCO1B1), mRNA.
ACCESSION NM_006446
VERSION NM_006446.4 GI:225543524
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2800)
AUTHORS Zhou,Q., Chen,Q.X., Ruan,Z.R., Yuan,H., Xu,H.M. and Zeng,S.
TITLE CYP2C9*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and
gender are determinants of inter-subject variability in
pitavastatin pharmacokinetics
JOURNAL Pharmazie 68 (3), 187-194 (2013)
PUBMED 23556337
REMARK GeneRIF: Compared to non-SLCO1B1*17 carriers, SLCO1B1*17 carriers
had higher peak plasma concentration and AUC of the acid and
lactone forms of pivastatin
REFERENCE 2 (bases 1 to 2800)
AUTHORS Ulvestad,M., Skottheim,I.B., Jakobsen,G.S., Bremer,S., Molden,E.,
Asberg,A., Hjelmesaeth,J., Andersson,T.B., Sandbu,R. and
Christensen,H.
TITLE Impact of OATP1B1, MDR1, and CYP3A4 expression in liver and
intestine on interpatient pharmacokinetic variability of
atorvastatin in obese subjects
JOURNAL Clin. Pharmacol. Ther. 93 (3), 275-282 (2013)
PUBMED 23361102
REMARK GeneRIF: OATP1B1 phenotype is more important than CYP3A4 and MDR1
phenotypes for the individual pharmacokinetic variability of
atorvastatin.
REFERENCE 3 (bases 1 to 2800)
AUTHORS Yao,J., Hong,W., Huang,J., Zhan,K., Huang,H. and Hong,M.
TITLE N-Glycosylation dictates proper processing of organic anion
transporting polypeptide 1B1
JOURNAL PLoS ONE 7 (12), E52563 (2012)
PUBMED 23285087
REMARK GeneRIF: Asparagine residues that are possibly involved in
N-glycosylation were substituted with glutamine residues and
identified three glycosylation sites (Asn134, Asn503 and Asn516)
within the structure of OATP1B1.
REFERENCE 4 (bases 1 to 2800)
AUTHORS Jung,D., Hagenbuch,B., Gresh,L., Pontoglio,M., Meier,P.J. and
Kullak-Ublick,G.A.
TITLE Characterization of the human OATP-C (SLC21A6) gene promoter and
regulation of liver-specific OATP genes by hepatocyte nuclear
factor 1 alpha
JOURNAL J. Biol. Chem. 276 (40), 37206-37214 (2001)
PUBMED 11483603
REMARK GeneRIF: The promoter of SLC21A6 gene was characterized and
regulated by HNF 1alpha.
REFERENCE 5 (bases 1 to 2800)
AUTHORS Cui,Y., Konig,J., Leier,I., Buchholz,U. and Keppler,D.
TITLE Hepatic uptake of bilirubin and its conjugates by the human organic
anion transporter SLC21A6
JOURNAL J. Biol. Chem. 276 (13), 9626-9630 (2001)
PUBMED 11134001
REFERENCE 6 (bases 1 to 2800)
AUTHORS Konig,J., Cui,Y., Nies,A.T. and Keppler,D.
TITLE Localization and genomic organization of a new hepatocellular
organic anion transporting polypeptide
JOURNAL J. Biol. Chem. 275 (30), 23161-23168 (2000)
PUBMED 10779507
REFERENCE 7 (bases 1 to 2800)
AUTHORS Tamai,I., Nezu,J., Uchino,H., Sai,Y., Oku,A., Shimane,M. and
Tsuji,A.
TITLE Molecular identification and characterization of novel members of
the human organic anion transporter (OATP) family
JOURNAL Biochem. Biophys. Res. Commun. 273 (1), 251-260 (2000)
PUBMED 10873595
REFERENCE 8 (bases 1 to 2800)
AUTHORS Konig,J., Cui,Y., Nies,A.T. and Keppler,D.
TITLE A novel human organic anion transporting polypeptide localized to
the basolateral hepatocyte membrane
JOURNAL Am. J. Physiol. Gastrointest. Liver Physiol. 278 (1), G156-G164
(2000)
PUBMED 10644574
REFERENCE 9 (bases 1 to 2800)
AUTHORS Hsiang,B., Zhu,Y., Wang,Z., Wu,Y., Sasseville,V., Yang,W.P. and
Kirchgessner,T.G.
TITLE A novel human hepatic organic anion transporting polypeptide
(OATP2). Identification of a liver-specific human organic anion
transporting polypeptide and identification of rat and human
hydroxymethylglutaryl-CoA reductase inhibitor transporters
JOURNAL J. Biol. Chem. 274 (52), 37161-37168 (1999)
PUBMED 10601278
REFERENCE 10 (bases 1 to 2800)
AUTHORS Abe,T., Kakyo,M., Tokui,T., Nakagomi,R., Nishio,T., Nakai,D.,
Nomura,H., Unno,M., Suzuki,M., Naitoh,T., Matsuno,S. and Yawo,H.
TITLE Identification of a novel gene family encoding human liver-specific
organic anion transporter LST-1
JOURNAL J. Biol. Chem. 274 (24), 17159-17163 (1999)
PUBMED 10358072
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC020696.1, AF205071.1 and
AC022335.8.
This sequence is a reference standard in the RefSeqGene project.
On Mar 21, 2009 this sequence version replaced gi:141801825.
Summary: This gene encodes a liver-specific member of the organic
anion transporter family. The encoded protein is a transmembrane
receptor that mediates the sodium-independent uptake of numerous
endogenous compounds including bilirubin, 17-beta-glucuronosyl
estradiol and leukotriene C4. This protein is also involved in the
removal of drug compounds such as statins, bromosulfophthalein and
rifampin from the blood into the hepatocytes. Polymorphisms in the
gene encoding this protein are associated with impaired transporter
function. [provided by RefSeq, Mar 2009].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF205071.1, AB026257.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025088 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-8 BC020696.1 2-9
9-491 AF205071.1 39-521
492-492 AC022335.8 82644-82644 c
493-2800 AF205071.1 523-2830
FEATURES Location/Qualifiers
source 1..2800
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12p"
gene 1..2800
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/note="solute carrier organic anion transporter family,
member 1B1"
/db_xref="GeneID:10599"
/db_xref="HGNC:10959"
/db_xref="MIM:604843"
exon 1..43
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
misc_feature 1
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/note="transcription start site"
exon 44..188
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
misc_feature 45..47
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/note="upstream in-frame stop codon"
variation 80
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:373658115"
variation 91
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:201251518"
variation 102
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:180888034"
CDS 105..2180
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/note="solute carrier family 21 (organic anion
transporter), member 6; sodium-independent organic
anion-transporting polypeptide 2; liver-specific organic
anion transporter 1; OATP-2; solute carrier family 21
member 6"
/codon_start=1
/product="solute carrier organic anion transporter family
member 1B1"
/protein_id="NP_006437.3"
/db_xref="GI:225543525"
/db_xref="CCDS:CCDS8685.1"
/db_xref="GeneID:10599"
/db_xref="HGNC:10959"
/db_xref="MIM:604843"
/translation="
MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASENGSVMDEANLESLNKNKHFVPSAGADSETHC
"
misc_feature 183..1970
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/note="Organic Anion Transporter Polypeptide (OATP)
family; Region: OATP; pfam03137"
/db_xref="CDD:202550"
misc_feature 189..248
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 306..368
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 387..461
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature <600..>806
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature 609..695
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 753..815
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 870..944
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 1098..1163
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 1224..1295
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 1308..1379
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 1467..1628
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/note="The kazal-type serine protease inhibitor domain has
been detected in an extracellular loop region of solute
carrier 21 (SLC21) family members (organic anion
transporters) , which may regulate the specificity of
anion uptake. The KAZAL_SLC21 domain is a...; Region:
KAZAL_SLC21; cd01330"
/db_xref="CDD:29001"
misc_feature 1716..1784
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 1812..1889
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
misc_feature 1992..2045
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
transmembrane region"
variation 105
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:185905373"
variation 132
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:11557087"
variation 134
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:113635866"
variation 159
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:376829525"
variation 170
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:142087529"
variation 183
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:190581845"
exon 189..330
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 189
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:146317972"
variation 220
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:370556411"
variation 273
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:139257324"
variation 274
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:61760182"
variation 288
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:144164853"
variation 314
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:148697674"
variation 315
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:373327528"
variation 321
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:56101265"
exon 331..463
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 339
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:370130036"
variation 349
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:56061388"
variation 359
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:71581978"
variation 402
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:144508550"
variation 421
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:200227560"
exon 464..585
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 492
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:2306283"
variation 505
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:202074496"
variation 514
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:151204465"
variation 515
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:11045818"
variation 523
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:147450830"
variation 527
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:368095348"
variation 556
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:2306282"
variation 559
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:145144129"
variation 567
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:11045819"
variation 571
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:72559745"
variation 578
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:140730264"
exon 586..732
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 589
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:138374684"
variation 622
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:141467543"
variation 625
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:4149056"
variation 639
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:371375183"
variation 645
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:138965366"
variation 646
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:142101690"
variation 663
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:200331427"
variation 675
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:4149057"
variation 681
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:376996580"
variation 682
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:72559746"
variation 695
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:148105486"
variation 697
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:376755211"
variation 701
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:2291075"
variation 703
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:150623527"
variation 710
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:369764409"
variation 712
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:4603354"
exon 733..831
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 735
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:184348772"
variation 737
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:201722521"
variation 742
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:372477451"
variation 765
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:377502108"
variation 766
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:139691245"
variation 768
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:79135870"
variation 778
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:370943869"
variation 799
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:374328647"
variation 807
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:147421160"
variation 817
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:374113543"
exon 832..1074
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 837
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:11045852"
variation 861
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:183501729"
variation 862
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:11045853"
variation 912
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:201438350"
variation 926
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:192911820"
variation 938
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:182303784"
variation 944..945
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace=""
/replace="a"
/db_xref="dbSNP:72559742"
variation 944
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:199712476"
variation 958
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:148647456"
variation 986
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:11045854"
variation 1002
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:139907543"
variation 1048
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:373619379"
variation 1068
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:201363750"
exon 1075..1239
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 1085
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:151155254"
variation 1104
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:77871475"
variation 1111
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:72559747"
variation 1116..1117
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace=""
/replace="gt"
/db_xref="dbSNP:113495867"
variation 1138
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:61760243"
variation 1139
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:145167231"
variation 1147
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:146867151"
variation 1162
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:55901008"
variation 1180
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:147750118"
variation 1184
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:140674443"
variation 1190
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:57040246"
variation 1211
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:377208842"
exon 1240..1435
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 1281
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:373127202"
variation 1290
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:200621156"
variation 1304
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:59113707"
variation 1317
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:376060151"
variation 1330
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:199859384"
variation 1350
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:77468276"
variation 1352
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:11045859"
variation 1376
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:61176925"
variation 1393
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:143266211"
variation 1398
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:56387224"
variation 1412
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:139049237"
variation 1413
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:142965323"
variation 1423
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:139797371"
variation 1426
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:141779296"
variation 1431
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:150573622"
exon 1436..1601
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 1489
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:72559748"
variation 1511
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:374859808"
variation 1556
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:74064211"
variation 1560
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:202110446"
variation 1567
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:59502379"
variation 1569
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:144733213"
variation 1582
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:145491008"
variation 1599
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:74064213"
exon 1602..1786
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 1612
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:368423244"
variation 1636
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:200319276"
variation 1668
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:112909948"
variation 1677
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:71581987"
variation 1693
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:184762532"
variation 1726
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:71581988"
variation 1732
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:72661137"
variation 1745
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:200158405"
variation 1755
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:375465421"
exon 1787..1851
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 1796
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:146415464"
variation 1819
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:201987253"
variation 1820
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:373681186"
variation 1828
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:74700754"
variation 1833
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:371102023"
variation 1836
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:201001269"
variation 1842
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:71581941"
exon 1852..1969
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 1884
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:199945870"
variation 1888
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:139026094"
variation 1897
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:201861991"
variation 1898
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:201556175"
variation 1913
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:143812591"
variation 1940
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:370991447"
variation 1941
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:377350683"
variation 1969
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:368052440"
exon 1970..2787
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/inference="alignment:Splign:1.39.8"
variation 1981
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:183624077"
variation 1982
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:200526972"
variation 2014
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:112560299"
variation 2033
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:34671512"
variation 2068
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:56199088"
variation 2082
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:368443740"
variation 2104
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:55737008"
variation 2136
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:200995543"
variation 2142
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:375293385"
variation 2144
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:200467000"
variation 2149
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:140790673"
variation 2161
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:201158567"
variation 2166
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:367879427"
variation 2199
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:113870212"
STS 2203..2306
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/standard_name="RH1600"
/db_xref="UniSTS:10796"
variation 2220
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:79775553"
variation 2226
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:71581985"
variation 2238
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:113192433"
variation 2262
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:72655363"
variation 2301
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="g"
/db_xref="dbSNP:74064260"
variation 2347
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:4149085"
variation 2389
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:201787919"
variation 2508
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:4149086"
variation 2585
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:112204127"
variation 2619
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="g"
/replace="t"
/db_xref="dbSNP:4149087"
variation 2629
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:11045891"
variation 2643
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/db_xref="dbSNP:4149088"
variation 2661
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="c"
/replace="t"
/db_xref="dbSNP:71581986"
variation 2681
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="t"
/db_xref="dbSNP:372380851"
variation 2755
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:61760249"
polyA_signal 2763..2768
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
variation 2785
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
/replace="a"
/replace="c"
/db_xref="dbSNP:141979092"
polyA_site 2787
/gene="SLCO1B1"
/gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
OATPC; SLC21A6"
ORIGIN
aaagggtggacttgttgcagttgctgtaggattctaaatccaggtgattgtttcaaactgagcatcaacaacaaaaacatttgtatgatatctatatttcaatcatggaccaaaatcaacatttgaataaaacagcagaggcacaaccttcagagaataagaaaacaagatactgcaatggattgaagatgttcttggcagctctgtcactcagctttattgctaagacactaggtgcaattattatgaaaagttccatcattcatatagaacggagatttgagatatcctcttctcttgttggttttattgacggaagctttgaaattggaaatttgcttgtgattgtatttgtgagttactttggatccaaactacatagaccaaagttaattggaatcggttgtttcattatgggaattggaggtgttttgactgctttgccacatttcttcatgggatattacaggtattctaaagaaactaatatcaattcatcagaaaattcaacatcgaccttatccacttgtttaattaatcaaattttatcactcaatagagcatcacctgagatagtgggaaaaggttgtttaaaggaatctgggtcatacatgtggatatatgtgttcatgggtaatatgcttcgtggaataggggagactcccatagtaccattggggctttcttacattgatgatttcgctaaagaaggacattcttctttgtatttaggtatattgaatgcaatagcaatgattggtccaatcattggctttaccctgggatctctgttttctaaaatgtacgtggatattggatatgtagatctaagcactatcaggataactcctactgattctcgatgggttggagcttggtggcttaatttccttgtgtctggactattctccattatttcttccataccattctttttcttgccccaaactccaaataaaccacaaaaagaaagaaaagcttcactgtctttgcatgtgctggaaacaaatgatgaaaaggatcaaacagctaatttgaccaatcaaggaaaaaatattaccaaaaatgtgactggttttttccagtcttttaaaagcatccttactaatcccctgtatgttatgtttgtgcttttgacgttgttacaagtaagcagctatattggtgcttttacttatgtcttcaaatacgtagagcaacagtatggtcagccttcatctaaggctaacatcttattgggagtcataaccatacctatttttgcaagtggaatgtttttaggaggatatatcattaaaaaattcaaactgaacaccgttggaattgccaaattctcatgttttactgctgtgatgtcattgtccttttacctattatattttttcatactctgtgaaaacaaatcagttgccggactaaccatgacctatgatggaaataatccagtgacatctcatagagatgtaccactttcttattgcaactcagactgcaattgtgatgaaagtcaatgggaaccagtctgtggaaacaatggaataacttacatctcaccctgtctagcaggttgcaaatcttcaagtggcaataaaaagcctatagtgttttacaactgcagttgtttggaagtaactggtctccagaacagaaattactcagcccatttgggtgaatgcccaagagatgatgcttgtacaaggaaattttacttttttgttgcaatacaagtcttgaatttatttttctctgcacttggaggcacctcacatgtcatgctgattgttaaaattgttcaacctgaattgaaatcacttgcactgggtttccactcaatggttatacgagcactaggaggaattctagctccaatatattttggggctctgattgatacaacgtgtataaagtggtccaccaacaactgtggcacacgtgggtcatgtaggacatataattccacatcattttcaagggtctacttgggcttgtcttcaatgttaagagtctcatcacttgttttatatattatattaatttatgccatgaagaaaaaatatcaagagaaagatatcaatgcatcagaaaatggaagtgtcatggatgaagcaaacttagaatccttaaataaaaataaacattttgtcccttctgctggggcagatagtgaaacacattgttaaggggagaaaaaaagccacttctgcttctgtgtttccaaacagcattgcattgattcagtaagatgttatttttgaggagttcctggtcctttcactaagaatttccacatcttttatggtggaagtataaataagcctatgaacttataataaaacaaactgtaggtagaaaaaatgagagtactcattgttacattatagctacatatttgtggttaaggttagactatatgatccatacaaattaaagtgagagacatggttactgtgtaataaaagaaaaaatacttgttcaggtaattctaattcttaataaaacaaatgagtatcatacaggtagaggttaaaaaggaggagctagattcatatcctaagtaaagagaaatgcctagtgtctattttattaaacaaacaaacacagagtttgaactataatactaaggcctgaagtctagcttggatatatgctacaataatatctgttactcacataaaattatatatttcacagactttatcaatgtataattaacaattatcttgtttaagtaaatttagaatacatttaagtattgtggaagaaataaagacattccaatatttgcaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:10599 -> Molecular function: GO:0015347 [sodium-independent organic anion transmembrane transporter activity] evidence: TAS
GeneID:10599 -> Biological process: GO:0008206 [bile acid metabolic process] evidence: TAS
GeneID:10599 -> Biological process: GO:0015711 [organic anion transport] evidence: TAS
GeneID:10599 -> Biological process: GO:0015721 [bile acid and bile salt transport] evidence: TAS
GeneID:10599 -> Biological process: GO:0043252 [sodium-independent organic anion transport] evidence: TAS
GeneID:10599 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
GeneID:10599 -> Biological process: GO:0055085 [transmembrane transport] evidence: TAS
GeneID:10599 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:10599 -> Cellular component: GO:0005887 [integral to plasma membrane] evidence: TAS
GeneID:10599 -> Cellular component: GO:0016020 [membrane] evidence: TAS
GeneID:10599 -> Cellular component: GO:0016323 [basolateral plasma membrane] evidence: IEA
by
@meso_cacase at
DBCLS
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