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2025-05-09 16:38:15, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_003486 4543 bp mRNA linear PRI 09-JUN-2013
DEFINITION Homo sapiens solute carrier family 7 (amino acid transporter light
chain, L system), member 5 (SLC7A5), mRNA.
ACCESSION NM_003486 NM_015923
VERSION NM_003486.5 GI:71979931
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4543)
AUTHORS Elorza,A., Soro-Arnaiz,I., Melendez-Rodriguez,F.,
Rodriguez-Vaello,V., Marsboom,G., de Carcer,G., Acosta-Iborra,B.,
Albacete-Albacete,L., Ordonez,A., Serrano-Oviedo,L.,
Gimenez-Bachs,J.M., Vara-Vega,A., Salinas,A., Sanchez-Prieto,R.,
Martin del Rio,R., Sanchez-Madrid,F., Malumbres,M., Landazuri,M.O.
and Aragones,J.
TITLE HIF2alpha acts as an mTORC1 activator through the amino acid
carrier SLC7A5
JOURNAL Mol. Cell 48 (5), 681-691 (2012)
PUBMED 23103253
REMARK GeneRIF: HIF-2alpha/mTORC1/SLC7A5 pathway mediates proliferation
and tumor promoting properties of HIF-2alpha.
REFERENCE 2 (bases 1 to 4543)
AUTHORS Yanagisawa,N., Ichinoe,M., Mikami,T., Nakada,N., Hana,K.,
Koizumi,W., Endou,H. and Okayasu,I.
TITLE High expression of L-type amino acid transporter 1 (LAT1) predicts
poor prognosis in pancreatic ductal adenocarcinomas
JOURNAL J. Clin. Pathol. 65 (11), 1019-1023 (2012)
PUBMED 22813728
REMARK GeneRIF: LAT1 aberrant overexpression in pancreatic ductal
adenocarcinomas predicts poor prognosis, independent of Ki-67 LI,
and offers a potential target for future anticancer therapy with
its inhibitors.
REFERENCE 3 (bases 1 to 4543)
AUTHORS Hayashi,K., Jutabha,P., Endou,H. and Anzai,N.
TITLE c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human
pancreatic cancer cells
JOURNAL Oncol. Rep. 28 (3), 862-866 (2012)
PUBMED 22736142
REMARK GeneRIF: The LAT1 promoter has a canonical c-Myc binding sequence
and overexpression of c-Myc increased LAT1 promoter activity.
REFERENCE 4 (bases 1 to 4543)
AUTHORS Yamamoto,S., Kimura,T., Tachiki,T., Anzai,N., Sakurai,T. and
Ushimaru,M.
TITLE The involvement of L-type amino acid transporters in theanine
transport
JOURNAL Biosci. Biotechnol. Biochem. 76 (12), 2230-2235 (2012)
PUBMED 23221699
REMARK GeneRIF: L-theanine is transported mostly via the system L
transport pathway and its isoforms
REFERENCE 5 (bases 1 to 4543)
AUTHORS Kaira,K., Oriuchi,N., Takahashi,T., Nakagawa,K., Ohde,Y.,
Okumura,T., Murakami,H., Shukuya,T., Kenmotsu,H., Naito,T.,
Kanai,Y., Endo,M., Kondo,H., Nakajima,T. and Yamamoto,N.
TITLE L-type amino acid transporter 1 (LAT1) expression in malignant
pleural mesothelioma
JOURNAL Anticancer Res. 31 (12), 4075-4082 (2011)
PUBMED 22199264
REMARK GeneRIF: analysis of L-type amino acid transporter 1 (LAT1)
expression in malignant pleural mesothelioma
REFERENCE 6 (bases 1 to 4543)
AUTHORS Pfeiffer,R., Rossier,G., Spindler,B., Meier,C., Kuhn,L. and
Verrey,F.
TITLE Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and
members of the glycoprotein-associated amino acid transporter
family
JOURNAL EMBO J. 18 (1), 49-57 (1999)
PUBMED 9878049
REFERENCE 7 (bases 1 to 4543)
AUTHORS Torrents,D., Estevez,R., Pineda,M., Fernandez,E., Lloberas,J.,
Shi,Y.B., Zorzano,A. and Palacin,M.
TITLE Identification and characterization of a membrane protein (y+L
amino acid transporter-1) that associates with 4F2hc to encode the
amino acid transport activity y+L. A candidate gene for lysinuric
protein intolerance
JOURNAL J. Biol. Chem. 273 (49), 32437-32445 (1998)
PUBMED 9829974
REFERENCE 8 (bases 1 to 4543)
AUTHORS Mastroberardino,L., Spindler,B., Pfeiffer,R., Skelly,P.J.,
Loffing,J., Shoemaker,C.B. and Verrey,F.
TITLE Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a
permease family
JOURNAL Nature 395 (6699), 288-291 (1998)
PUBMED 9751058
REFERENCE 9 (bases 1 to 4543)
AUTHORS Maglott,D.R., Durkin,A.S., Lane,S.A., Callen,D.F., Feldblyum,T.V.
and Nierman,W.C.
TITLE The gene for membrane protein E16 (D16S469E) maps to human
chromosome 16q24.3 and is expressed in human brain, thymus, and
retina
JOURNAL Genomics 23 (1), 303-304 (1994)
PUBMED 7829099
REFERENCE 10 (bases 1 to 4543)
AUTHORS Gaugitsch,H.W., Prieschl,E.E., Kalthoff,F., Huber,N.E. and
Baumruker,T.
TITLE A novel transiently expressed, integral membrane protein linked to
cell activation. Molecular cloning via the rapid degradation signal
AUUUA
JOURNAL J. Biol. Chem. 267 (16), 11267-11273 (1992)
PUBMED 1597461
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BC039692.2, BC042600.1 and AC126696.1.
On Aug 9, 2005 this sequence version replaced gi:34222350.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC039692.2, BC042600.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025088 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-416 BC039692.2 26-441
417-1826 BC042600.1 411-1820
1827-4543 AC126696.1 64838-67554 c
FEATURES Location/Qualifiers
source 1..4543
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q24.3"
gene 1..4543
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/note="solute carrier family 7 (amino acid transporter
light chain, L system), member 5"
/db_xref="GeneID:8140"
/db_xref="HGNC:11063"
/db_xref="MIM:600182"
exon 1..610
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
variation 11
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:33968272"
variation 24
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:33996472"
CDS 73..1596
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/note="solute carrier family 7 (cationic amino acid
transporter, y+ system), member 5; 4F2 light chain; CD98
light chain; L-type amino acid transporter 1; integral
membrane protein E16; large neutral amino acids
transporter 1; sodium-independent neutral amino acid
transporter LAT1; 4F2 LC; solute carrier family 7 member
5; y+ system cationic amino acid transporter"
/codon_start=1
/product="large neutral amino acids transporter small
subunit 1"
/protein_id="NP_003477.4"
/db_xref="GI:71979932"
/db_xref="CCDS:CCDS10964.1"
/db_xref="GeneID:8140"
/db_xref="HGNC:11063"
/db_xref="MIM:600182"
/translation="
MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQET
"
misc_feature 163..165
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q01650.2); phosphorylation site"
misc_feature 175..177
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 190..1590
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/note="L-type amino acid transporter; Region: 2A0308;
TIGR00911"
/db_xref="CDD:162101"
misc_feature 205..207
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q01650.2); phosphorylation site"
misc_feature 220..282
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 322..384
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 430..492
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 508..570
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 580..642
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 667..729
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 799..861
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 892..954
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 1027..1089
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 1258..1320
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 1363..1425
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
misc_feature 1444..1506
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q01650.2);
transmembrane region"
variation 89
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:33983951"
variation 459
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:33913122"
variation 579
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="g"
/db_xref="dbSNP:33973691"
variation 603
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="g"
/db_xref="dbSNP:1137356"
exon 611..736
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
variation 669
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:33938662"
exon 737..842
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
variation 762
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="g"
/db_xref="dbSNP:1060250"
exon 843..887
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
exon 888..1011
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
variation 915
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:33992288"
exon 1012..1115
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
variation 1056
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:33936442"
variation 1080
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:1060251"
exon 1116..1212
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
variation 1203
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:2230174"
exon 1213..1362
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
exon 1363..1540
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
variation 1419
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="g"
/db_xref="dbSNP:11541881"
exon 1541..4543
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/inference="alignment:Splign:1.39.8"
variation 1885
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="t"
/db_xref="dbSNP:11117304"
variation 1905
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="g"
/db_xref="dbSNP:1060252"
variation 2034
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="g"
/db_xref="dbSNP:1060253"
variation 2036
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="c"
/db_xref="dbSNP:1060254"
STS 2078..2422
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/standard_name="SHGC-154007"
/db_xref="UniSTS:182982"
variation 2341
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="g"
/db_xref="dbSNP:11541879"
variation 2480
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="c"
/db_xref="dbSNP:730214"
variation 2878
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1060257"
variation 3150
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="g"
/db_xref="dbSNP:1060258"
variation 3455
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:11541880"
variation 3697
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="g"
/db_xref="dbSNP:1060266"
variation 3754
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="c"
/db_xref="dbSNP:11541884"
variation 3823
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="g"
/replace="t"
/db_xref="dbSNP:11541883"
variation 3903
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:16943300"
variation 4098
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="c"
/replace="t"
/db_xref="dbSNP:11117303"
variation 4192
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/replace="a"
/replace="t"
/db_xref="dbSNP:1803523"
STS 4253..4418
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/standard_name="RH69181"
/db_xref="UniSTS:1341"
STS 4329..4481
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/standard_name="RH47455"
/db_xref="UniSTS:2977"
STS 4411..4502
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/standard_name="D16S469E"
/db_xref="UniSTS:148427"
STS 4455..4543
/gene="SLC7A5"
/gene_synonym="4F2LC; CD98; D16S469E; E16; hLAT1; LAT1;
MPE16"
/standard_name="2084"
/db_xref="UniSTS:62431"
ORIGIN
cggcgggcggcgcgcacactgctcgctgggccgcggctcccgggtgtcccaggcccggccggtgcgcagagcatggcgggtgcgggcccgaagcggcgcgcgctagcggcgccggcggccgaggagaaggaagaggcgcgggagaagatgctggccgccaagagcgcggacggctcggcgccggcaggcgagggcgagggcgtgaccctgcagcggaacatcacgctgctcaacggcgtggccatcatcgtggggaccattatcggctcgggcatcttcgtgacgcccacgggcgtgctcaaggaggcaggctcgccggggctggcgctggtggtgtgggccgcgtgcggcgtcttctccatcgtgggcgcgctctgctacgcggagctcggcaccaccatctccaaatcgggcggcgactacgcctacatgctggaggtctacggctcgctgcccgccttcctcaagctctggatcgagctgctcatcatccggccttcatcgcagtacatcgtggccctggtcttcgccacctacctgctcaagccgctcttccccacctgcccggtgcccgaggaggcagccaagctcgtggcctgcctctgcgtgctgctgctcacggccgtgaactgctacagcgtgaaggccgccacccgggtccaggatgcctttgccgccgccaagctcctggccctggccctgatcatcctgctgggcttcgtccagatcgggaagggtgatgtgtccaatctagatcccaacttctcatttgaaggcaccaaactggatgtggggaacattgtgctggcattatacagcggcctctttgcctatggaggatggaattacttgaatttcgtcacagaggaaatgatcaacccctacagaaacctgcccctggccatcatcatctccctgcccatcgtgacgctggtgtacgtgctgaccaacctggcctacttcaccaccctgtccaccgagcagatgctgtcgtccgaggccgtggccgtggacttcgggaactatcacctgggcgtcatgtcctggatcatccccgtcttcgtgggcctgtcctgcttcggctccgtcaatgggtccctgttcacatcctccaggctcttcttcgtggggtcccgggaaggccacctgccctccatcctctccatgatccacccacagctcctcacccccgtgccgtccctcgtgttcacgtgtgtgatgacgctgctctacgccttctccaaggacatcttctccgtcatcaacttcttcagcttcttcaactggctctgcgtggccctggccatcatcggcatgatctggctgcgccacagaaagcctgagcttgagcggcccatcaaggtgaacctggccctgcctgtgttcttcatcctggcctgcctcttcctgatcgccgtctccttctggaagacacccgtggagtgtggcatcggcttcaccatcatcctcagcgggctgcccgtctacttcttcggggtctggtggaaaaacaagcccaagtggctcctccagggcatcttctccacgaccgtcctgtgtcagaagctcatgcaggtggtcccccaggagacatagccaggaggccgagtggctgccggaggagcatgcgcagaggccagttaaagtagatcacctcctcgaacccactccggttccccgcaacccacagctcagctgcccatcccagtccctcgccgtccctcccaggtcgggcagtggaggctgctgtgaaaactctggtacgaatctcatccctcaactgagggccagggacccaggtgtgcctgtgctcctgcccaggagcagcttttggtctccttgggccctttttcccttccctcctttgtttacttatatatatattttttttaaacttaaattttgggtcaacttgacaccactaagatgattttttaaggagctgggggaaggcaggagccttcctttctcctgccccaagggcccagaccctgggcaaacagagctactgagacttggaacctcattgctaccacagacttgcactgaagccggacagctgcccagacacatgggcttgtgacattcgtgaaaaccaaccctgtgggcttatgtctctgccttagggtttgcagagtggaaactcagccgtagggtggcactgggagggggtgggggatctgggcaaggtgggtgattcctcccaggaggtgcttgaggccccgatggactcctgaccataatcctagccccgagacaccatcctgagccagggaacagccccagggttggggggtgccggcatctcccctagctcaccaggcctggcctctgggcagtgtggcctcttggctatttctgtgtccagttttggaggctgagttctggttcatgcagacaaagccctgtccttcagtcttctagaaacagagacaagaaaggcagacacaccgcggccaggcacccatgtgggcgcccaccctgggctccacacagcagtgtcccctgccccagaggtcgcagctaccctcagcctccaatgcattggcctctgtaccgcccggcagccccttctggccggtgctgggttcccactcccggcctaggcacctccccgctctccctgtcacgctcatgtcctgtcctggtcctgatgcccgttgtctaggagacagagccaagcactgctcacgtctctgccgcctgcgtttggaggcccctgggctctcacccagtccccacccgcctgcagagagggaactagggcaccccttgtttctgttgttcccgtgaatttttttcgctatgggaggcagccgaggcctggccaatgcggcccactttcctgagctgtcgctgcctccatggcagcagccagggacccccagaacaagaagaccccgcaggatccctcctgagctcggggggctctgccttctcaggccccgggcttcccttctccccagccagaggtggagccaagtggtccagcgtcactccagtgctcagctgtggctggaggagctggcctgtggcacagccctgagtgtcccaagccgggagccaacgaagccggacacggcttcactgaccagcggctgctcaagccgcaagctctcagcaagtgcccagtggagcctgccgcccccgcctgggcaccgggaccccctcaccatccagtgggcccggagaaacctgatgaacagtttggggactcaggaccagatgtccgtctctcttgcttgaggaatgaagacctttattcacccctgccccgttgcttcccgctgcacatggacagacttcacagcgtctgctcataggacctgcatccttcctggggacgaattccactcgtccaagggacagcccacggtctggaggccgaggaccaccagcaggcaggtggactgactgtgttgggcaagacctcttccctctgggcctgttctcttggctgcaaataaggacagcagctggtgccccacctgcctggtgcattgctgtgtgaatccaggaggcagtggacatcgtaggcagccacggccccgggtccaggagaagtgctccctggaggcacgcaccactgcttcccactggggccggcggggcccacgcacgacgtcagcctcttaccttcccgcctcggctaggggtcctcgggatgccgttctgttccaacctcctgctctgggacgtggacatgcctcaaggatacagggagccggcggcctctcgacggcacgcacttgcctgttggctgctgcggctgtgggcgagcatgggggctgccagcgtctgttgtggaaagtagctgctagtgaaatggctggggccgctggggtccgtcttcacactgcgcaggtctcttctgggcgtctgagctggggtgggagctcctccgcagaaggttggtggggggtccagtctgtgatccttggtgctgtgtgccccactccagcctggggaccccacttcagaaggtaggggccgtgtcccgcggtgctgactgaggcctgcttccccctccccctcctgctgtgctggaattccacagggaccagggccaccgcaggggactgtctcagaagacttgatttttccgtccctttttctccacactccactgacaaacgtccccagcggtttccacttgtgggcttcaggtgttttcaagcacaacccaccacaacaagcaagtgcattttcagtcgttgtgcttttttgttttgtgctaacgtcttactaatttaaagatgctgtcggcaccatgtttatttatttccagtggtcatgctcagccttgctgctctgcgtggcgcaggtgccatgcctgctccctgtctgtgtcccagccacgcagggccatccactgtgacgtcggccgaccaggctggacaccctctgccgagtaatgacgtgtgtggctgggaccttctttattctgtgttaatggctaacctgttacactgggctgggttgggtagggtgttctggcttttttgtggggtttttatttttaaagaaacactcaatcatccta
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:8140 -> Molecular function: GO:0015171 [amino acid transmembrane transporter activity] evidence: ISS
GeneID:8140 -> Molecular function: GO:0015175 [neutral amino acid transmembrane transporter activity] evidence: TAS
GeneID:8140 -> Molecular function: GO:0015179 [L-amino acid transmembrane transporter activity] evidence: IEA
GeneID:8140 -> Molecular function: GO:0042605 [peptide antigen binding] evidence: ISS
GeneID:8140 -> Biological process: GO:0006520 [cellular amino acid metabolic process] evidence: TAS
GeneID:8140 -> Biological process: GO:0006810 [transport] evidence: TAS
GeneID:8140 -> Biological process: GO:0006811 [ion transport] evidence: TAS
GeneID:8140 -> Biological process: GO:0006865 [amino acid transport] evidence: TAS
GeneID:8140 -> Biological process: GO:0007399 [nervous system development] evidence: IEA
GeneID:8140 -> Biological process: GO:0007596 [blood coagulation] evidence: TAS
GeneID:8140 -> Biological process: GO:0015804 [neutral amino acid transport] evidence: ISS
GeneID:8140 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
GeneID:8140 -> Biological process: GO:0050900 [leukocyte migration] evidence: TAS
GeneID:8140 -> Biological process: GO:0055085 [transmembrane transport] evidence: TAS
GeneID:8140 -> Cellular component: GO:0005829 [cytosol] evidence: IEA
GeneID:8140 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:8140 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:8140 -> Cellular component: GO:0016324 [apical plasma membrane] evidence: IEA
by
@meso_cacase at
DBCLS
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