Home |
Help |
Advanced search
2025-05-09 17:21:57, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001184794 3391 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens par-3 partitioning defective 3 homolog (C. elegans)
(PARD3), transcript variant 11, mRNA.
ACCESSION NM_001184794
VERSION NM_001184794.1 GI:296278205
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3391)
AUTHORS Xue,B., Krishnamurthy,K., Allred,D.C. and Muthuswamy,S.K.
TITLE Loss of Par3 promotes breast cancer metastasis by compromising
cell-cell cohesion
JOURNAL Nat. Cell Biol. 15 (2), 189-200 (2013)
PUBMED 23263278
REMARK GeneRIF: Suggest that loss of Par3 promotes metastatic behaviour of
ErbB2-induced breast tumour epithelial cells by decreasing
cell-cell cohesion.
REFERENCE 2 (bases 1 to 3391)
AUTHORS McCaffrey,L.M., Montalbano,J., Mihai,C. and Macara,I.G.
TITLE Loss of the Par3 polarity protein promotes breast tumorigenesis and
metastasis
JOURNAL Cancer Cell 22 (5), 601-614 (2012)
PUBMED 23153534
REMARK GeneRIF: Par3 is identified as a regulator of signaling pathways
relevant to invasive breast cancer.
REFERENCE 3 (bases 1 to 3391)
AUTHORS Yang,Z., Xue,B., Umitsu,M., Ikura,M., Muthuswamy,S.K. and Neel,B.G.
TITLE The signaling adaptor GAB1 regulates cell polarity by acting as a
PAR protein scaffold
JOURNAL Mol. Cell 47 (3), 469-483 (2012)
PUBMED 22883624
REMARK GeneRIF: The scaffolding adaptor GAB1 interacts with two polarity
proteins, PAR1 and PAR3.
REFERENCE 4 (bases 1 to 3391)
AUTHORS Gao,Y., Chen,X., Shangguan,S., Bao,Y., Lu,X., Zou,J., Guo,J.,
Dai,Y. and Zhang,T.
TITLE Association study of PARD3 gene polymorphisms with neural tube
defects in a Chinese Han population
JOURNAL Reprod Sci 19 (7), 764-771 (2012)
PUBMED 22447895
REMARK GeneRIF: genetic association studies in a Chinese Han population:
Data suggest that 6 SNPs in PARD3 (rs2496720, rs2252655, rs3851068,
rs118153230, rs10827337, rs12218196) are associated with neural
tube defects/anencephaly in this population.
REFERENCE 5 (bases 1 to 3391)
AUTHORS Odell,A.F., Hollstein,M., Ponnambalam,S. and Walker,J.H.
TITLE A VE-cadherin-PAR3-alpha-catenin complex regulates the Golgi
localization and activity of cytosolic phospholipase A(2)alpha in
endothelial cells
JOURNAL Mol. Biol. Cell 23 (9), 1783-1796 (2012)
PUBMED 22398721
REMARK GeneRIF: A VE-cadherin-PAR3-alpha-catenin complex regulates the
Golgi localization and activity of cytosolic phospholipase
A(2)alpha in endothelial cells.(
REFERENCE 6 (bases 1 to 3391)
AUTHORS Ebnet,K., Suzuki,A., Horikoshi,Y., Hirose,T., Meyer Zu
Brickwedde,M.K., Ohno,S. and Vestweber,D.
TITLE The cell polarity protein ASIP/PAR-3 directly associates with
junctional adhesion molecule (JAM)
JOURNAL EMBO J. 20 (14), 3738-3748 (2001)
PUBMED 11447115
REFERENCE 7 (bases 1 to 3391)
AUTHORS Suzuki,A., Yamanaka,T., Hirose,T., Manabe,N., Mizuno,K.,
Shimizu,M., Akimoto,K., Izumi,Y., Ohnishi,T. and Ohno,S.
TITLE Atypical protein kinase C is involved in the evolutionarily
conserved par protein complex and plays a critical role in
establishing epithelia-specific junctional structures
JOURNAL J. Cell Biol. 152 (6), 1183-1196 (2001)
PUBMED 11257119
REFERENCE 8 (bases 1 to 3391)
AUTHORS Noda,Y., Takeya,R., Ohno,S., Naito,S., Ito,T. and Sumimoto,H.
TITLE Human homologues of the Caenorhabditis elegans cell polarity
protein PAR6 as an adaptor that links the small GTPases Rac and
Cdc42 to atypical protein kinase C
JOURNAL Genes Cells 6 (2), 107-119 (2001)
PUBMED 11260256
REFERENCE 9 (bases 1 to 3391)
AUTHORS Johansson,A., Driessens,M. and Aspenstrom,P.
TITLE The mammalian homologue of the Caenorhabditis elegans polarity
protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and
Rac1
JOURNAL J. Cell. Sci. 113 (PT 18), 3267-3275 (2000)
PUBMED 10954424
REFERENCE 10 (bases 1 to 3391)
AUTHORS Joberty,G., Petersen,C., Gao,L. and Macara,I.G.
TITLE The cell-polarity protein Par6 links Par3 and atypical protein
kinase C to Cdc42
JOURNAL Nat. Cell Biol. 2 (8), 531-539 (2000)
PUBMED 10934474
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AL450337.24, AF332592.1, AK024668.1 and BE464617.1.
Summary: This gene encodes a member of the PARD protein family.
PARD family members interact with other PARD family members and
other proteins; they affect asymmetrical cell division and direct
polarized cell growth. Multiple alternatively spliced transcript
variants have been described for this gene. [provided by RefSeq,
Oct 2011].
Transcript Variant: This variant (11) lacks an alternate, in-frame,
exon, uses two different splice sites, lacks most of the 3' coding
region, and contains a different segment for its 3' end, compared
to variant 1. The resulting protein (isoform 11) is shorter and has
a distinct C-terminus when it is compared to isoform 1. This
variant has also been called 'short variant b'.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF332592.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-330 AL450337.24 22044-22373 c
331-2858 AF332592.1 1-2528
2859-3034 AK024668.1 640-815
3035-3297 AF332592.1 2705-2967
3298-3391 BE464617.1 1-94 c
FEATURES Location/Qualifiers
source 1..3391
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10p11.21"
gene 1..3391
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="par-3 partitioning defective 3 homolog (C.
elegans)"
/db_xref="GeneID:56288"
/db_xref="HGNC:16051"
/db_xref="MIM:606745"
exon 1..450
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
misc_feature 172..174
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="upstream in-frame stop codon"
CDS 331..3297
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="isoform 11 is encoded by transcript variant 11;
partitioning defective 3 homolog; atypical PKC
isotype-specific interacting protein; PAR3-alpha; CTCL
tumor antigen se2-5; atypical PKC
isotype-specific-interacting protein; bazooka"
/codon_start=1
/product="partitioning defective 3 homolog isoform 11"
/protein_id="NP_001171723.1"
/db_xref="GI:296278206"
/db_xref="CCDS:CCDS53513.1"
/db_xref="GeneID:56288"
/db_xref="HGNC:16051"
/db_xref="MIM:606745"
/translation="
MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFSLAKLKPEKR
"
misc_feature 331..768
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="Domain of unknown function (DUF3534); Region:
DUF3534; pfam12053"
/db_xref="CDD:152488"
misc_feature 1144..1371
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="PDZ domain found in a variety of Eumetazoan
signaling molecules, often in tandem arrangements. May be
responsible for specific protein-protein interactions, as
most PDZ domains bind C-terminal polypeptides, and binding
to internal (non-C-terminal)...; Region: PDZ_signaling;
cd00992"
/db_xref="CDD:29049"
misc_feature order(1177..1188,1192..1194,1348..1353,1360..1365)
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="protein binding site [polypeptide binding]; other
site"
/db_xref="CDD:29049"
misc_feature 1723..1962
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="PDZ domain found in a variety of Eumetazoan
signaling molecules, often in tandem arrangements. May be
responsible for specific protein-protein interactions, as
most PDZ domains bind C-terminal polypeptides, and binding
to internal (non-C-terminal)...; Region: PDZ_signaling;
cd00992"
/db_xref="CDD:29049"
misc_feature order(1738..1749,1753..1755,1909..1914,1921..1926)
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="protein binding site [polypeptide binding]; other
site"
/db_xref="CDD:29049"
misc_feature 2053..2334
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="PDZ domain found in a variety of Eumetazoan
signaling molecules, often in tandem arrangements. May be
responsible for specific protein-protein interactions, as
most PDZ domains bind C-terminal polypeptides, and binding
to internal (non-C-terminal)...; Region: PDZ_signaling;
cd00992"
/db_xref="CDD:29049"
misc_feature order(2089..2100,2104..2106,2263..2268,2275..2280)
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/note="protein binding site [polypeptide binding]; other
site"
/db_xref="CDD:29049"
exon 451..552
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 553..733
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 734..912
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 913..1044
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 1045..1136
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 1137..1220
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 1221..1346
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 1347..1729
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 1730..1869
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 1870..1998
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 1999..2187
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 2188..2358
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
variation 2260
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/replace="g"
/replace="t"
/db_xref="dbSNP:11540925"
exon 2359..2509
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 2510..2699
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 2700..2761
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 2762..2806
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 2807..3034
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 3035..3266
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
exon 3267..3389
/gene="PARD3"
/gene_synonym="ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A;
SE2-5L16; SE2-5LT1; SE2-5T2"
/inference="alignment:Splign:1.39.8"
ORIGIN
cccagcggccccgagcgagcgccagcgccacacagccccgggcagccgccggcgagcgcgccgcgacgccgaacaggtggccggaggctgcgggcgccgcggcggggagaggcgaggcaagccccgggcgaagcgaggcgaggcgagggcggccgggccgggcatgcgagctgagcggccccccggcgtcgccgccgcctgcccgcgcccctagccgcccgcgcgcccgagtccccagcggctcctccgcgcccagcgtcctcggtcccggcctcggctgctccggctgcgctcggcgaggggcgcgggcccgcccgcggcggcggcggcatgaaagtgaccgtgtgcttcggacggacccgggtggtcgtgccgtgcggggacggccacatgaaagttttcagcctcatccagcaggcggtgacccgctaccggaaggccatcgccaaggatccaaactactggatacaggtgcatcgcttggaacatggagatggaggaatactagaccttgatgacattctttgtgatgtagcagacgataaagacagactggtagcagtgtttgatgagcaggatccacatcacggaggtgatggcaccagtgccagttccacgggtacccagagcccagagatatttggtagtgagcttggcaccaacaatgtctcagcctttcagccttaccaagcaacaagtgaaattgaggtcacaccttcagtccttcgagcaaatatgcctcttcatgttcgacgcagtagtgacccagctctaattggcctctccacttctgtcagtgatagtaatttttcctctgaagagccttcaaggaaaaatcccacacgctggtcaacaacagctggcttcctcaagcagaacactgctgggagtcctaaaacctgcgacaggaagaaagatgaaaactacagaagcctcccgcgggatactagtaactggtctaaccaatttcagagagacaatgctcgctcgtctctgagtgccagtcacccaatggtgggcaagtggctggagaaacaagaacaggatgaggatgggacagaagaggataacagtcgtgttgaacctgttggacatgctgacacgggtttggagcatatacccaacttttctctggatgatatggtaaagctcgtagaagtccccaacgatggagggcctctgggaatccatgtagtgcctttcagtgctcgaggcggcagaaccctggggttattagtaaaacgattggagaaaggtggtaaagctgaacatgaaaatctttttcgtgagaatgattgcattgtcaggattaatgatggcgaccttcgaaatagaagatttgaacaagcacaacatatgtttcgccaagccatgcgtacacccatcatttggttccatgtggttcctgcagcaaataaagagcagtatgaacaactatcccaaagtgagaagaacaattactattcaagccgttttagccctgacagccagtatattgacaacaggagtgtgaacagtgcagggcttcacacggtgcagagagcaccccgactgaaccacccgcctgagcagatagactctcactcaagactacctcatagcgcacacccctcgggaaaaccaccatccgctccagcctcggcacctcagaatgtatttagtacgactgtaagcagtggttataacaccaaaaaaataggcaagaggcttaatatccagcttaagaaaggtacagaaggtttgggattcagcatcacttccagagatgtaacaataggtggctcagctccaatctatgtgaaaaacattctcccccggggggcggccattcaggatggccgacttaaggcaggagacagacttatagaggtaaatggagtagatttagtgggcaaatcccaagaggaagttgtttcgctgttgagaagcaccaagatggaaggaactgtgagccttctggtctttcgccaggaagacgccttccacccaagggaactgaaagcagaagatgaggatattgttcttacacctgatggcaccagggaatttctgacatttgaagtcccacttaatgattcaggatctgcaggccttggtgtcagtgtcaaaggtaaccggtcaaaagagaaccacgcagatttgggaatctttgtcaagtccattattaatggaggagcagcatctaaagatggaaggcttcgggtgaatgatcaactgatagcagtaaatggagaatccctgttgggcaagacaaaccaagatgccatggaaaccctaagaaggtctatgtctactgaaggcaataaacgaggaatgatccagcttattgttgcaaggagaataagcaagtgcaatgagctgaagtcacctgggagcccccctggacctgagctgcccattgaaacagcgttggatgatagagaacgaagaatttcccattccctctacagtgggattgaggggcttgatgaatcgcccagcagaaatgctgccctcagtaggataatgggtaaataccagctgtcccctacagtgaatatgccccaagatgacactgtcattatagaagatgacaggttgccagtgcttcctccacatctctctgaccagtcctcttccagctcccatgatgatgtggggtttgtgacggcagatgctggtacttgggccaaggctgcaatcagtgattcagccgactgctctttgagtccagatgttgatccagttcttgcttttcaacgagaaggatttggacgtcagatagctgacgagactaaactcaatacagtggatgaccagaaagcaggttctcccagcagagatgtgggtccttccctgggtctgaagaagtcaagctcgttggagagtctgcagaccgcagttgccgaggtgactttgaatggggatattcctttccatcgtccacggccgcggataatcagaggcaggggatgcaatgagagcttcagagctgccatcgacaaatcttatgataaacccgcggtagatgatgatgatgaaggcatggagaccttggaagaagacacagaagaaagttcaagatcagggagagagtctgtatccacagccagtgatcagccttcccactctctggagagacaaatgaatggaaaccaagagaaaggtgataagactgatagaaaaaaggataaaactggaaaagaaaagaagaaagatagagataaggagaaggataaaatgaaagccaagaagggaatgctgaagggcttgggagacatgttcagccttgccaaactgaagcccgagaagagatgaacaacaaagcgattcaaaacatgtcttgaacagcacatattgcacagttgttgttttttttaaacaaacaataaatttacttttaatgaattaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:56288 -> Molecular function: GO:0005080 [protein kinase C binding] evidence: IEA
GeneID:56288 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:56288 -> Molecular function: GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding] evidence: ISS
GeneID:56288 -> Molecular function: GO:0005547 [phosphatidylinositol-3,4,5-trisphosphate binding] evidence: ISS
GeneID:56288 -> Molecular function: GO:0019903 [protein phosphatase binding] evidence: IEA
GeneID:56288 -> Molecular function: GO:0032266 [phosphatidylinositol-3-phosphate binding] evidence: ISS
GeneID:56288 -> Biological process: GO:0000226 [microtubule cytoskeleton organization] evidence: IEA
GeneID:56288 -> Biological process: GO:0003383 [apical constriction] evidence: IEA
GeneID:56288 -> Biological process: GO:0006461 [protein complex assembly] evidence: TAS
GeneID:56288 -> Biological process: GO:0006612 [protein targeting to membrane] evidence: ISS
GeneID:56288 -> Biological process: GO:0007049 [cell cycle] evidence: IEA
GeneID:56288 -> Biological process: GO:0007163 [establishment or maintenance of cell polarity] evidence: TAS
GeneID:56288 -> Biological process: GO:0007179 [transforming growth factor beta receptor signaling pathway] evidence: TAS
GeneID:56288 -> Biological process: GO:0007205 [protein kinase C-activating G-protein coupled receptor signaling pathway] evidence: TAS
GeneID:56288 -> Biological process: GO:0007409 [axonogenesis] evidence: TAS
GeneID:56288 -> Biological process: GO:0008356 [asymmetric cell division] evidence: TAS
GeneID:56288 -> Biological process: GO:0032970 [regulation of actin filament-based process] evidence: IEA
GeneID:56288 -> Biological process: GO:0034329 [cell junction assembly] evidence: TAS
GeneID:56288 -> Biological process: GO:0044319 [wound healing, spreading of cells] evidence: IEA
GeneID:56288 -> Biological process: GO:0045216 [cell-cell junction organization] evidence: TAS
GeneID:56288 -> Biological process: GO:0051642 [centrosome localization] evidence: IEA
GeneID:56288 -> Biological process: GO:0060341 [regulation of cellular localization] evidence: IEA
GeneID:56288 -> Biological process: GO:0070830 [tight junction assembly] evidence: ISS
GeneID:56288 -> Biological process: GO:0070830 [tight junction assembly] evidence: TAS
GeneID:56288 -> Biological process: GO:0090162 [establishment of epithelial cell polarity] evidence: ISS
GeneID:56288 -> Cellular component: GO:0005819 [spindle] evidence: IEA
GeneID:56288 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:56288 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:56288 -> Cellular component: GO:0005911 [cell-cell junction] evidence: IDA
GeneID:56288 -> Cellular component: GO:0005911 [cell-cell junction] evidence: ISS
GeneID:56288 -> Cellular component: GO:0005913 [cell-cell adherens junction] evidence: IEA
GeneID:56288 -> Cellular component: GO:0005923 [tight junction] evidence: IDA
GeneID:56288 -> Cellular component: GO:0005923 [tight junction] evidence: ISS
GeneID:56288 -> Cellular component: GO:0005938 [cell cortex] evidence: IEA
GeneID:56288 -> Cellular component: GO:0012505 [endomembrane system] evidence: IEA
GeneID:56288 -> Cellular component: GO:0030054 [cell junction] evidence: TAS
GeneID:56288 -> Cellular component: GO:0043025 [neuronal cell body] evidence: IEA
GeneID:56288 -> Cellular component: GO:0044295 [axonal growth cone] evidence: IEA
GeneID:56288 -> Cellular component: GO:0045177 [apical part of cell] evidence: IEA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.