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2025-05-09 16:58:05, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_000017 1934 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens acyl-CoA dehydrogenase, C-2 to C-3 short chain
(ACADS), mRNA.
ACCESSION NM_000017
VERSION NM_000017.2 GI:161377444
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1934)
AUTHORS Vatanavicharn,N., Liammongkolkul,S., Sakamoto,O.,
Sathienkijkanchai,A. and Wasant,P.
TITLE Phenotypic and mutation spectrums of Thai patients with isovaleric
acidemia
JOURNAL Pediatr Int 53 (6), 990-994 (2011)
PUBMED 22004070
REMARK GeneRIF: IVD mutations in Asian populations are distinct from these
in Western populations.
REFERENCE 2 (bases 1 to 1934)
AUTHORS Lucas,T.G., Henriques,B.J., Rodrigues,J.V., Bross,P., Gregersen,N.
and Gomes,C.M.
TITLE Cofactors and metabolites as potential stabilizers of mitochondrial
acyl-CoA dehydrogenases
JOURNAL Biochim. Biophys. Acta 1812 (12), 1658-1663 (2011)
PUBMED 21968293
REMARK GeneRIF: physiological concentrations of flavin adenine
dinucleotide resulted in a spectacular enhancement of the thermal
stabilities of SCAD and prevented enzymatic activity loss
REFERENCE 3 (bases 1 to 1934)
AUTHORS Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wagele B,
Altmaier E, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de
Angelis MH, Kastenmuller G, Kottgen A, Kronenberg F, Mangino M,
Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J,
Ried JS, Romisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G,
Illig T, Spector TD, Adamski J, Soranzo N and Gieger C.
CONSRTM CARDIoGRAM
TITLE Human metabolic individuality in biomedical and pharmaceutical
research
JOURNAL Nature 477 (7362), 54-60 (2011)
PUBMED 21886157
REMARK Publication Status: Online-Only
REFERENCE 4 (bases 1 to 1934)
AUTHORS Hornbak,M., Banasik,K., Justesen,J.M., Krarup,N.T., Sandholt,C.H.,
Andersson,A., Sandbaek,A., Lauritzen,T., Pisinger,C., Witte,D.R.,
Sorensen,T.A., Pedersen,O. and Hansen,T.
TITLE The minor C-allele of rs2014355 in ACADS is associated with reduced
insulin release following an oral glucose load
JOURNAL BMC Med. Genet. 12, 4 (2011)
PUBMED 21211036
REMARK GeneRIF: In glucose-tolerant individuals the minor C-allele of
rs2014355 of ACADS was associated with reduced measures of
glucose-stimulated insulin release during an oral glucose tolerance
test.
Publication Status: Online-Only
REFERENCE 5 (bases 1 to 1934)
AUTHORS Hendrickson,S.L., Lautenberger,J.A., Chinn,L.W., Malasky,M.,
Sezgin,E., Kingsley,L.A., Goedert,J.J., Kirk,G.D., Gomperts,E.D.,
Buchbinder,S.P., Troyer,J.L. and O'Brien,S.J.
TITLE Genetic variants in nuclear-encoded mitochondrial genes influence
AIDS progression
JOURNAL PLoS ONE 5 (9), E12862 (2010)
PUBMED 20877624
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 1934)
AUTHORS Kelly,C.L., Hinsdale,M.E. and Wood,P.A.
TITLE Cloning and characterization of the mouse short-chain acyl-CoA
dehydrogenase cDNA
JOURNAL Genomics 18 (1), 137-140 (1993)
PUBMED 8276399
REFERENCE 7 (bases 1 to 1934)
AUTHORS Vanhove,G., Van Veldhoven,P.P., Eyssen,H.J. and Mannaerts,G.P.
TITLE Mitochondrial short-chain acyl-CoA dehydrogenase of human liver and
kidney can function as an oxidase
JOURNAL Biochem. J. 292 (PT 1), 23-30 (1993)
PUBMED 8503850
REFERENCE 8 (bases 1 to 1934)
AUTHORS Hochstrasser,D.F., Frutiger,S., Paquet,N., Bairoch,A., Ravier,F.,
Pasquali,C., Sanchez,J.C., Tissot,J.D., Bjellqvist,B., Vargas,R. et
al.
TITLE Human liver protein map: a reference database established by
microsequencing and gel comparison
JOURNAL Electrophoresis 13 (12), 992-1001 (1992)
PUBMED 1286669
REFERENCE 9 (bases 1 to 1934)
AUTHORS Naito,E., Indo,Y. and Tanaka,K.
TITLE Identification of two variant short chain acyl-coenzyme A
dehydrogenase alleles, each containing a different point mutation
in a patient with short chain acyl-coenzyme A dehydrogenase
deficiency
JOURNAL J. Clin. Invest. 85 (5), 1575-1582 (1990)
PUBMED 1692038
REFERENCE 10 (bases 1 to 1934)
AUTHORS Naito,E., Ozasa,H., Ikeda,Y. and Tanaka,K.
TITLE Molecular cloning and nucleotide sequence of complementary DNAs
encoding human short chain acyl-coenzyme A dehydrogenase and the
study of the molecular basis of human short chain acyl-coenzyme A
dehydrogenase deficiency
JOURNAL J. Clin. Invest. 83 (5), 1605-1613 (1989)
PUBMED 2565344
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB487184.1, M26393.1 and
BU682624.1.
This sequence is a reference standard in the RefSeqGene project.
On Nov 30, 2007 this sequence version replaced gi:4557232.
Summary: This gene encodes a a tetrameric mitochondrial
flavoprotein, which is a member of the acyl-CoA dehydrogenase
family. This enzyme catalyzes the initial step of the mitochondrial
fatty acid beta-oxidation pathway. Mutations in this gene have been
associated with Short Chain Acyl-CoA Dehydrogenase Deficiency.
[provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC025963.1, M26393.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
gene product(s) localized to mito. :: reported by MitoCarta
##RefSeq-Attributes-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-96 DB487184.1 34-129
97-1598 M26393.1 11-1512
1599-1934 BU682624.1 1-336 c
FEATURES Location/Qualifiers
source 1..1934
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q24.31"
gene 1..1934
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/note="acyl-CoA dehydrogenase, C-2 to C-3 short chain"
/db_xref="GeneID:35"
/db_xref="HGNC:90"
/db_xref="HPRD:06053"
/db_xref="MIM:606885"
exon 1..164
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 1
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="c"
/db_xref="dbSNP:186841031"
CDS 119..1357
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/EC_number="1.3.8.1"
/note="acyl-Coenzyme A dehydrogenase, C-2 to C-3 short
chain; short-chain specific acyl-CoA dehydrogenase,
mitochondrial; butyryl-CoA dehydrogenase; unsaturated
acyl-CoA reductase; mitochondrial short-chain specific
acyl-CoA dehydrogenase; short-chain acyl-CoA
dehydrogenase"
/codon_start=1
/product="short-chain specific acyl-CoA dehydrogenase,
mitochondrial precursor"
/protein_id="NP_000008.1"
/db_xref="GI:4557233"
/db_xref="CCDS:CCDS9207.1"
/db_xref="GeneID:35"
/db_xref="HGNC:90"
/db_xref="HPRD:06053"
/db_xref="MIM:606885"
/translation="
MAAALLARASGPARRALCPRAWRQLHTIYQSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS
"
transit_peptide 119..190
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
mat_peptide 191..1354
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/product="short-chain specific acyl-CoA dehydrogenase,
mitochondrial"
misc_feature 215..1354
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
CaiA; COG1960"
/db_xref="CDD:32143"
misc_feature 224..1342
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/note="Short chain acyl-CoA dehydrogenases and eukaryotic
short/branched chain acyl-CoA dehydrogenases; Region:
SCAD_SBCAD; cd01158"
/db_xref="CDD:173847"
misc_feature order(572..574,581..583,599..601,671..673,677..679,
1211..1213,1223..1225,1292..1294)
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/note="FAD binding site [chemical binding]; other site"
/db_xref="CDD:173847"
misc_feature order(587..589,602..604,671..673,800..814,1007..1009,
1016..1018,1043..1045,1055..1060,1064..1066,1073..1075,
1097..1099,1166..1168,1199..1201,1211..1213,1226..1228,
1232..1234,1238..1243,1253..1255,1262..1267,1274..1279,
1283..1285,1304..1306,1313..1315,1322..1324)
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/note="homotetramer interface [polypeptide binding]; other
site"
/db_xref="CDD:173847"
misc_feature order(599..604,911..913,920..925,932..934,1016..1018,
1292..1294)
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/note="substrate binding pocket [chemical binding]; other
site"
/db_xref="CDD:173847"
misc_feature 923..934
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P16219.1);
Region: Substrate binding"
misc_feature 1292..1294
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/note="catalytic base [active]"
/db_xref="CDD:173847"
exon 165..328
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 165
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:147494970"
variation 177
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:139981498"
variation 242
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:143948985"
variation 254
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:121908003"
variation 265
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/db_xref="dbSNP:202193021"
variation 277
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:147303048"
variation 282
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:147442301"
variation 307
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="t"
/db_xref="dbSNP:371096896"
variation 311
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:377388400"
variation 321
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:148789330"
variation 322
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:374124706"
exon 329..478
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 333
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:142476255"
variation 343
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:370478896"
variation 346
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:375620690"
variation 367
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:150507331"
variation 373
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:113118479"
variation 374
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:374930037"
variation 386
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:121908005"
variation 392
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="g"
/replace="t"
/db_xref="dbSNP:121908004"
variation 402
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:369400082"
variation 412
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:143169456"
variation 428..430
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace=""
/replace="gag"
/db_xref="dbSNP:387906308"
variation 437
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:61732144"
variation 439
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:3914"
variation 440
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:117356004"
variation 441
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:387906951"
variation 445
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:144083614"
variation 478
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:76543640"
exon 479..590
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 480
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/db_xref="dbSNP:372873554"
variation 531
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:17848085"
variation 532
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:201825471"
variation 535
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/db_xref="dbSNP:149107232"
variation 541
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:2239686"
variation 542
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:375450502"
variation 543
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/db_xref="dbSNP:148297461"
variation 578
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:368500899"
variation 583
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:141492002"
exon 591..742
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 616
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:187551593"
variation 625
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:147038701"
variation 629
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:1800556"
variation 640
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:143925225"
variation 647
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:57443665"
variation 693
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:28940874"
variation 696
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:369167716"
variation 720
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:151059234"
exon 743..913
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 743
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:1799958"
variation 772
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="c"
/db_xref="dbSNP:149430391"
variation 773
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="t"
/db_xref="dbSNP:144815059"
variation 774
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:148588313"
variation 786
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:143131689"
variation 787
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:17848089"
variation 790
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:373660425"
exon 914..1051
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 926
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:370283455"
variation 933
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:374726386"
variation 937
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:368859841"
variation 943
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:200652158"
variation 944
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:199717731"
variation 968
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:201430078"
variation 973
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:372164287"
variation 979
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:375272147"
variation 1006
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:111686208"
variation 1018
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:150980955"
variation 1032
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/db_xref="dbSNP:550921"
exon 1052..1147
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 1091
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:121908006"
variation 1106
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:140853839"
variation 1107
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:199633532"
variation 1108
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:3915"
variation 1129
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="c"
/db_xref="dbSNP:200346345"
exon 1148..1204
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 1149
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:387906950"
variation 1171
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:145594828"
variation 1172
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="g"
/replace="t"
/db_xref="dbSNP:202078273"
variation 1176
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:28941773"
variation 1183
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:697853"
variation 1186
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:377559470"
exon 1205..1917
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/inference="alignment:Splign:1.39.8"
variation 1213
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="g"
/replace="t"
/db_xref="dbSNP:368469075"
variation 1222
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:200165866"
variation 1223
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:145466253"
variation 1235
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:371934737"
variation 1248
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:183161718"
variation 1249
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:374867417"
variation 1256
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:28940875"
variation 1257
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:368064268"
variation 1265
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:28940872"
variation 1266
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:35233375"
variation 1267
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:371323002"
variation 1271
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="g"
/replace="t"
/db_xref="dbSNP:202124189"
variation 1313
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="c"
/db_xref="dbSNP:375931905"
variation 1316
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:369840561"
variation 1324
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:374043146"
variation 1327
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:377069922"
variation 1349
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:369416846"
variation 1362
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:2229533"
variation 1378
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/db_xref="dbSNP:3916"
variation 1384
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:188190117"
variation 1393
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:372567027"
variation 1394
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:377080695"
variation 1438
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:371172924"
variation 1443
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:374762327"
variation 1472
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:2229534"
variation 1557
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:137990231"
variation 1606
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:628909"
variation 1630
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:369720260"
variation 1667
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="g"
/db_xref="dbSNP:116733542"
variation 1674
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="c"
/replace="t"
/db_xref="dbSNP:373553465"
variation 1738
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="g"
/replace="t"
/db_xref="dbSNP:192425836"
variation 1744
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:11065238"
STS 1750..1895
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/standard_name="RH75794"
/db_xref="UniSTS:87176"
variation 1857
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:639667"
variation 1884
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:9204"
polyA_signal 1897..1902
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
polyA_site 1917
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
variation 1917
/gene="ACADS"
/gene_synonym="ACAD3; SCAD"
/replace="a"
/replace="g"
/db_xref="dbSNP:113752987"
ORIGIN
cggccccgctcccgaggccctacgggcgtggcctctgtcccgggtcccgccccccagcactccggaacagcgcgctcgcagcgggaggtcgcgaagcctgggactgtgtctgtcgcccatggccgccgcgctgctcgcccgggcctcgggccctgcccgcagagctctctgtcctagggcctggcggcagttacacaccatctaccagtctgtggaactgcccgagacacaccagatgttgctccagacatgccgggactttgccgagaaggagttgtttcccattgcagcccaggtggataaggaacatctcttcccagcggctcaggtgaagaagatgggcgggcttgggcttctggccatggacgtgcccgaggagcttggcggtgctggcctcgattacctggcctacgccatcgccatggaggagatcagccgtggctgcgcctccaccggagtcatcatgagtgtcaacaactctctctacctggggcccatcttgaagtttggctccaaggagcagaagcaggcgtgggtcacgcctttcaccagtggtgacaaaattggctgctttgccctcagcgaaccagggaacggcagtgatgcaggagctgcgtccaccaccgcccgggccgagggcgactcatgggttctgaatggaaccaaagcctggatcaccaatgcctgggaggcttcggctgccgtggtctttgccagcacggacagagccctgcaaaacaagggcatcagtgccttcctggtccccatgccaacgcctgggctcacgttggggaagaaagaagacaagctgggcatccggggctcatccacggccaacctcatctttgaggactgtcgcatccccaaggacagcatcctgggggagccagggatgggcttcaagatagccatgcaaaccctggacatgggccgcatcggcatcgcctcccaggccctgggcattgcccagaccgccctcgattgtgctgtgaactacgctgagaatcgcatggccttcggggcgcccctcaccaagctccaggtcatccagttcaagttggcagacatggccctggccctggagagtgcccggctgctgacctggcgcgctgccatgctgaaggataacaagaagcctttcatcaaggaggcagccatggccaagctggccgcctcggaggccgcgaccgccatcagccaccaggccatccagatcctgggcggcatgggctacgtgacagagatgccggcagagcggcactaccgcgacgcccgcatcactgagatctacgagggcaccagcgaaatccagcggctggtgatcgccgggcatctgctcaggagctaccggagctgagcccgcggcggactgccccaggactgcgggaaggcgcgggagccaggggcctccaccccaaccccggctcagagactgggcggcccggcgggggctccctggggaccccagatgggctcagtgctgccacccagatcagatcacatgggaatgaggccctccgaccattggcagctccgcctctgggcctttccgcctcctcaccactgtgcctcaagttcctcatctaagtggccctggcctcctgggggcggggttgtgggggggctgagcgacactcagggacacctcagttgtcctcccgcgggccctggtgccctggcatgaaggcccagtgcgacaggcccttggtggggtctgtcttttccttgaggtcagaggtcaggagcagggctggggtcaggatgacgaggcctggggtcctggtgttgggcaggtggtggggctgggccatggagctggcccagaggcccctcagccctttgtaaagtctgatgaaggcaggggtggtgattcatgctgtgtgactgactgtgggtaataaacacacctgtcccccaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:35 -> Molecular function: GO:0000062 [fatty-acyl-CoA binding] evidence: IEA
GeneID:35 -> Molecular function: GO:0003995 [acyl-CoA dehydrogenase activity] evidence: TAS
GeneID:35 -> Molecular function: GO:0004085 [butyryl-CoA dehydrogenase activity] evidence: IEA
GeneID:35 -> Molecular function: GO:0050660 [flavin adenine dinucleotide binding] evidence: IEA
GeneID:35 -> Biological process: GO:0006635 [fatty acid beta-oxidation] evidence: TAS
GeneID:35 -> Biological process: GO:0033539 [fatty acid beta-oxidation using acyl-CoA dehydrogenase] evidence: IEA
GeneID:35 -> Biological process: GO:0042594 [response to starvation] evidence: IEA
GeneID:35 -> Biological process: GO:0044255 [cellular lipid metabolic process] evidence: TAS
GeneID:35 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
GeneID:35 -> Biological process: GO:0046359 [butyrate catabolic process] evidence: IEA
GeneID:35 -> Biological process: GO:0051289 [protein homotetramerization] evidence: IEA
GeneID:35 -> Biological process: GO:0051384 [response to glucocorticoid stimulus] evidence: IEA
GeneID:35 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
GeneID:35 -> Cellular component: GO:0005759 [mitochondrial matrix] evidence: TAS
GeneID:35 -> Cellular component: GO:0031966 [mitochondrial membrane] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_000008 -> EC 1.3.8.1
by
@meso_cacase at
DBCLS
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