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2025-05-09 17:20:09, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_199462 7791 bp mRNA linear PRI 15-JUN-2013
DEFINITION Homo sapiens dual serine/threonine and tyrosine protein kinase
(DSTYK), transcript variant 2, mRNA.
ACCESSION NM_199462 XM_290898
VERSION NM_199462.2 GI:218563734
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7791)
AUTHORS Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
Gibbs,R.A. and Butte,N.F.
TITLE Novel genetic loci identified for the pathophysiology of childhood
obesity in the Hispanic population
JOURNAL PLoS ONE 7 (12), E51954 (2012)
PUBMED 23251661
REFERENCE 2 (bases 1 to 7791)
AUTHORS Peng,J., Dong,W., Chen,Y., Mo,R., Cheng,J.F., Hui,C.C., Mohandas,N.
and Huang,C.H.
TITLE Dusty protein kinases: primary structure, gene evolution, tissue
specific expression and unique features of the catalytic domain
JOURNAL Biochim. Biophys. Acta 1759 (11-12), 562-572 (2006)
PUBMED 17123648
REMARK GeneRIF: Confocal imaging of transiently expressed human Dusty-GFP
fusion proteins showed a cytoplasmic distribution.
REFERENCE 3 (bases 1 to 7791)
AUTHORS Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
TITLE A germline-specific class of small RNAs binds mammalian Piwi
proteins
JOURNAL Nature 442 (7099), 199-202 (2006)
PUBMED 16751776
REFERENCE 4 (bases 1 to 7791)
AUTHORS Zha,J., Zhou,Q., Xu,L.G., Chen,D., Li,L., Zhai,Z. and Shu,H.B.
TITLE RIP5 is a RIP-homologous inducer of cell death
JOURNAL Biochem. Biophys. Res. Commun. 319 (2), 298-303 (2004)
PUBMED 15178406
REFERENCE 5 (bases 1 to 7791)
AUTHORS Robertson,N.G., Khetarpal,U., Gutierrez-Espeleta,G.A., Bieber,F.R.
and Morton,C.C.
TITLE Isolation of novel and known genes from a human fetal cochlear cDNA
library using subtractive hybridization and differential screening
JOURNAL Genomics 23 (1), 42-50 (1994)
PUBMED 7829101
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC060870.1, BC053627.1,
AC093422.3 and AY429674.1.
On Dec 20, 2008 this sequence version replaced gi:40806180.
Summary: This gene encodes a dual serine/threonine and tyrosine
protein kinase which is expressed in multiple tissues. It is
thought to function as a regulator of cell death. Multiple
transcript variants encoding different isoforms have been found for
this gene. [provided by RefSeq, Dec 2008].
Transcript Variant: This variant (2) lacks an in-frame exon in the
3' coding region, as compared to variant 1. The encoded isoform 2
is missing an internal segment, as compared to isoform 1.
##Evidence-Data-START##
Transcript exon combination :: BC053627.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025098 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-37 BC060870.1 1-37
38-1984 BC053627.1 1-1947
1985-1985 AC093422.3 54347-54347 c
1986-3404 BC053627.1 1949-3367
3405-7791 AY429674.1 3512-7898
FEATURES Location/Qualifiers
source 1..7791
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q32.1"
gene 1..7791
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/note="dual serine/threonine and tyrosine protein kinase"
/db_xref="GeneID:25778"
/db_xref="HGNC:29043"
/db_xref="HPRD:11495"
/db_xref="MIM:612666"
exon 1..329
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
CDS 65..2719
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/EC_number="2.7.12.1"
/note="isoform 2 is encoded by transcript variant 2;
receptor interacting protein 5; receptor interacting
protein kinase 5; dusty protein kinase; sgK496; dusty PK;
sugen kinase 496; RIP-homologous kinase;
receptor-interacting serine/threonine-protein kinase 5"
/codon_start=1
/product="dual serine/threonine and tyrosine protein
kinase isoform 2"
/protein_id="NP_955749.1"
/db_xref="GI:40806181"
/db_xref="CCDS:CCDS1452.1"
/db_xref="GeneID:25778"
/db_xref="HGNC:29043"
/db_xref="HPRD:11495"
/db_xref="MIM:612666"
/translation="
MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHNHTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQDCNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAHQGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDLVNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESERSPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAKALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGARPERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRLCKSNSEQPNRGLDDST
"
misc_feature 2021..2620
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/note="Serine/Threonine protein kinases, catalytic domain;
Region: S_TKc; smart00220"
/db_xref="CDD:197582"
misc_feature 2036..2620
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/note="Catalytic domain of Protein Kinases; Region: PKc;
cd00180"
/db_xref="CDD:173623"
misc_feature order(2036..2050,2060..2062,2099..2101,2105..2107,
2195..2197,2264..2275,2279..2281,2393..2395,2399..2401,
2405..2410,2414..2416,2447..2449,2456..2458,2495..2506)
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/note="active site"
/db_xref="CDD:173623"
misc_feature order(2036..2050,2060..2062,2099..2101,2105..2107,
2195..2197,2264..2275,2393..2395,2399..2401,2405..2410,
2414..2416,2447..2449)
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:173623"
misc_feature order(2048..2050,2279..2281,2393..2395,2399..2401,
2405..2407,2456..2458,2495..2506)
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:173623"
misc_feature order(2444..2464,2495..2506)
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/note="activation loop (A-loop); other site"
/db_xref="CDD:173623"
exon 330..718
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
exon 719..1388
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
STS 929..1016
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="SHGC-76207"
/db_xref="UniSTS:17625"
STS 980..1063
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="STS-M62021"
/db_xref="UniSTS:26245"
exon 1389..1621
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
exon 1622..1705
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
exon 1706..1882
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
exon 1883..2012
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
exon 2013..2169
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
variation 2092
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/replace="c"
/replace="t"
/db_xref="dbSNP:1062715"
exon 2170..2302
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
exon 2303..2416
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
exon 2417..2531
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
exon 2532..7774
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/inference="alignment:Splign:1.39.8"
STS 2764..2966
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="HSC26A082"
/db_xref="UniSTS:76608"
variation 2770
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/replace="a"
/replace="t"
/db_xref="dbSNP:11367"
STS 2831..3006
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="SHGC-76213"
/db_xref="UniSTS:41049"
polyA_site 3019
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
STS 3198..3388
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="STS-N25749"
/db_xref="UniSTS:37728"
STS 3245..3365
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="SHGC-76208"
/db_xref="UniSTS:74468"
STS 3513..4645
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 3513..3602
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
variation 4255
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/replace="g"
/replace="t"
/db_xref="dbSNP:1061132"
variation 4306
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/replace="c"
/replace="t"
/db_xref="dbSNP:11240369"
STS 4416..4537
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="SHGC-76193"
/db_xref="UniSTS:10283"
STS 4611..4700
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="PMC156606P1"
/db_xref="UniSTS:271408"
variation 4740
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/replace=""
/replace="c"
/db_xref="dbSNP:67700841"
variation 5572
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/replace="c"
/replace="t"
/db_xref="dbSNP:3183297"
STS 6676..6829
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="RH69217"
/db_xref="UniSTS:10312"
STS 6773..6874
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="SHGC-76211"
/db_xref="UniSTS:70767"
STS 6900..7086
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="D1S1361"
/db_xref="UniSTS:149557"
STS 6900..7014
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="D10S16"
/db_xref="UniSTS:155756"
STS 7616..7741
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/standard_name="SHGC-76209"
/db_xref="UniSTS:18928"
variation 7619
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/replace="c"
/replace="t"
/db_xref="dbSNP:1046925"
polyA_signal 7751..7756
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
variation 7762
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
/replace="c"
/replace="t"
/db_xref="dbSNP:7554368"
polyA_site 7774
/gene="DSTYK"
/gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
ORIGIN
ggggaggagggaggccgggcctgcggccggggaccgagccgcaaagacagagcgggcagaggcgatggagggcgacggggtgccatggggcagcgagcccgtctcgggtcccggccccggcggcggcggaatgatccgcgagctgtgccggggcttcggccgctaccgccgctacctgggacggctgcgacagaacctgcgcgagacccagaagttcttccgcgacatcaagtgctcccacaaccacacttgtctctcctccctcacgggcggcggcggggccgagcgcggccctgcaggcgatgtcgccgaaaccgggctgcaggcgggccaactgagctgcatttccttcccacctaaggaagagaagtacctccagcagattgtggactgcctcccttgcatactgatcctcggccaggattgtaacgtcaagtgccagctgttgaatctgctgttgggggtgcaggtgcttcccaccaccaagctgggcagtgaggagagctgtaagcttcggcgcctccgcttcacctatgggactcagactcgggtcagcctggcgctccctggacagtatgaactagtgcacacgctggttgctcatcagggcaactgggagaccatccctgaggaggatctggaggtccaagagaacaatgaggatgctgctcatgttttagcggaactggaggtaacgatgcaccatgctctcttacaggaagtggacgttgtggtagcaccatgccaaggcctccggcccacagtggatgttctgggtgacttggtgaatgatttcttgcctgtgataacctatgcactccacaaagatgaactctctgagagggatgagcaagagcttcaggaaatccgaaagtatttctcctttcctgtattctttttcaaagtgccgaaactgggctcggagataatagactcctcaaccaggagaatggagagcgaaagatcaccgctttatcgccagctaattgacctgggctatctgagcagcagtcactggaactgtggggctcctggccaggatactaaagctcagagcatgttggtggaacagagtgaaaagctgagacacttgagcacattttctcaccaggtgttacagactcgcctggtggatgcagccaaggccctgaacctggtgcactgccactgccttgacatctttattaaccaggcatttgacatgcagcgggacctgcagatcactcccaaacgtctggaatatactcgaaaaaaggagaatgagttgtatgaatcattgatgaatattgccaaccgaaagcaggaggaaatgaaggatatgattgttgagacacttaataccatgaaggaggaacttctggatgatgctactaacatggagtttaaagacgtcattgtccctgagaatggagaaccagtaggcaccagagagatcaaatgctgcatccgacagatccaggaactcatcatctcccgacttaatcaggcagtggctaataagctgatcagctcagtggattacctgagggaaagcttcgtcggaaccctggaacgatgtctgcagagcctggagaagtctcaggatgtctcagttcacatcaccagtaattatctcaaacagatcttaaatgctgcctatcatgttgaagtcacgtttcactcagggtcgtcagttacaaggatgctatgggagcaaatcaaacagatcatccagcgcatcacatgggtgagcccacctgccatcactctggaatggaagaggaaggtggcccaggaagccattgagagcctcagcgcctccaaattggctaagagcatttgcagccaattccggactcggctcaatagttcccacgaggcttttgcagcctccttgcggcagctggaagctggccactcaggccggttagagaaaacggaagatctatggctgagggttcggaaagatcatgctccccgcctggcccgcctttctctggaaagctgttctttacaggatgtcttgcttcatcgtaaacctaaactgggacaggaactgggccggggccagtatggtgtggtatacctgtgtgacaactggggaggacacttcccttgtgccctcaaatcagttgtccctccagatgagaagcactggaatgatctggctttggaatttcactatatgaggtctctgccgaagcatgagcgattggtggatctccatggttcagtcattgactacaactatggtggtggctccagcattgctgtgctcctcattatggagcggctacaccgggatctctacacagggctgaaggctgggctgaccctggagacacgtttgcagatagcactagatgtggtggagggaatccgcttcctgcacagccagggacttgtccatcgtgatatcaaactgaaaaatgtgctgctggataagcagaaccgtgccaagatcactgacttaggattctgcaagccagaggccatgatgtcaggcagcattgtggggacaccaatccatatggcccctgaacttttcacaggggctcgcccagaacgtcttcctgtgtttgatgaggagtgctggcagttgatggaagcctgttgggatggcgaccccttgaagaggcctctcttgggcattgtccagcccatgctccagggcatcatgaatcggctctgcaagtccaattctgagcagccaaacagaggactagatgattctacttgaaagcaaagacctttctctttcactctctagttatttccttccccctcaccttttggccatggggagaatttgacatttattcactataggacacactcccaagggaactggtgcttgctgggaaacttggaaccttcccaggcagggatgactcctggacagtgaagagttgaatgactgagcatattcagcagctcactgaagcgccaagctatccctttagcaaaaaagtgtctcagatgtgtaaaagctgaggaatgtggtgttctggcttcacaaatgaaaaggaggcagatgttaccattgtcttttcactgtatatacttctaagacagcaagcgggacactgcagtggcaatagtgttaaaaaatctcattctcatgatttttggctctagctaggaatagtttagtcaggactcagaaaatttgagcttagttctgggattatgaaaacatggggacaaaaacaataacttgtggatgtctggttcctgctgtctgcagccaggtatctcaggttgcaatggtcagaagtcccagtgagggagctagaaacagagctatctgttcctcatagtgccagtgtgtttacatttataggaccacatatccctggtttctgggggagggtttcactgttacatcaccaagaggccctgaaaagaggaaaaaaaaaaaaaaagaggccaggcatggtggctcacgcctgtaatctcagcactttgggaggctgaggcgggcggatcacaaggtccagagttcaagagcagcctggccaacatggtgaaaccccgtctctactaaagatacaaaaaattagccgggcgtggtggtgcatgcctgtaatccaagatactcaggaggctgaggcaggagaatcgcttgaacctgggaggcggaggttgcagtgagccgagatcatgccattgcactccagcctgggcgacagagtgagactctgtctcaaaaaaaaaaaaaaaatagaatgtgtatgcatatatttgtgtgtatatgtatatatgtgtgtgtgtctatatctctatctatatagacatacacacaggagttattggatttagagttactgctaaccccagaacagaatctgttcttttacctttgagtcttttcttttgtttacctcttttcatctcaaagtgggaaagctccagataacatggtacttaggagtgagtgtctaagcaaaaccaacccaatgcgaagtatttgggtgagaactgagaggtgggagatgattggaggccatggcctatgtacaaacatactggaagaaaaccagcttgtttttaaaacttaacacaatcagaaatttttctttttgtgtttgaatctaacacactgacgtttggaaaacttgatcaatgagcttttaaccacgatttctcccgcaatttgttccttctttttacctttttaaaaatctgttagaagaaaaaaagcagcagacgaaagagaaaaaccctcctctggtagttctgtgtgtgcccctcacccctgtgtgctagtgtctgggaagtttccctgaaaggtgggaggcgggtgggtggtcttttggagggttcctcatgaagtgtgcttgaggaaagaaattctgattctaggcagaggaaggggaacaatttaaatattggtgcatctcagatgcacttgacttcaagccttcctcaaccaaactggtccattagattccgaaaaacaggtagacgaggaagtagacagtggaagtgagtagtctccctccatctgcctaatccccaataactgtggtctggcccctgtgttcagcccgagagtttgtaaaacaggtccccaggtaggtgtataagatgagttgcaaattagccgggcatgctggcacgcaccagtaatcccagctacttgggaggctgaggcaggagaatcacttgaacccgggaggcagaggtcatggtgagccgagatcacgccactgcactccagcctgggcaacagagcgagactctatctcaaaaaaaaacaaaaaaaaaaacaaaaaacaaagatgagtcgcacatctgctgctgggattttctagggttgtctatgacagaatgaccatcttttaaatattaatggagtataaatggagtctataatgggtctttcatataacttttaactctttggctatcctgggctctgatcatgatatgtttgagcatagtagctccctaaactcttggagcctttcagaaattccatgtagtgctaataacctttttacttgcaaatgataaagtaactgactcagtgtctttgggctctgcaggctttagccttgttttggtaggatgttcagtatattctcagaatttttaccacctatttagctatacttcaagtactctattctctgcactaacttactgtccttctgggaactatgatggggcttcaagggagtcaggtgtcaagaaaggaggggtaagtactctctacttgctggaaaatcattgtaagtctgttgtgtatgaaattttaggaaaagtcttatatagttccctttccagactgttttcttttgactctaactataatcataagtctgtgcttccattatgaaggtcacattcctagcattcttgggaagtattagctcatactctcattcacatatgggaggttagatttttttcctctacccagagtccctttttagtttaccccacggcttagtttgctgtcagataccagttctctagcagattccccaacagttttttccccagtggggagggtggaagggagggactgatataagtaaggagatgagtagttgtgttacagttcattttctttaaaaaaaagtattttgagaaaaggtgcaaaatattcttgaaagtctctaggccagccaaagtccacatatggatatttggggatgttatttaaatactcagcaggctgagtgcaggtatacgtgtgtatagagtgtgtatactttgcttttgttttataacattgtcagctaattttggctttgttctttggcatccattcttattataagtgatggaatgccatgaaatgtactgtattgtatattacttgggaggacactaggttttcaaagaagtctggcagcacttgggttatagagggctcagcatgaccaaagtcctaaagattttacctcccagctttggttgtatgtgttcccaagtggtgaggtgagattgtggctggaggaagaaaaaggatggcatgaaagaatgacccttattgtggtctgtccttctaatcaacataattagggcagcttaccccaacatgaaaatgatgacctggccatttttaatggccagagcttgaagtctggtctctcattttgtttcagaaatgagtgagaggccttcctgcagagcagtcaggagaaatggtggagcctggggccctggaatggctgaccctgtgcctagagagctgatggcaagggctgtctggcatggctcatttgggtggggtttccccaggcataccttagttccctgatcctctgcaaagagtagctcattgactgagcaagcgcttcaggaggactgtgctggttgttcccagaccaaagagagtcacttttgactccatcaacttcaaggggacagagcctaggcagcagattctcctaatttttaacactaaaattcaaggaagcagtggaggaaagaatgcattactaccacagatagaaataggggactcatagaactctcgactagtacctgtcagctctcaaatgcattcttgtgtctttgcttgagctgccaaagaagggtcacaaagtgttcttcctcatggaagaagtgcctcggggttgcagggctgcaaagtgacaactgcactgaatgacactttattttttggctttggcttattatttagcactgggaggcccaggggaattggtgattacagtagcactttgggaagttaaagccccctttgggcttgctttggagagatgatggcatgcttggtattccatttggataatcaggaagcctccctagtccatccatattgtgtcagagtgggattaacaaccctggaagagtccactgccaaaagagtagttgctttcctggaatttccaaagcttttggattttctggatcaagtaacccactttttaaaacctgaggtcaggagttcgagaccagcctggtaacatggtgaaaccccgtctctattaaaaatagaaaaaattagccaggcatggtggcgggcacctatagtcccagctactcaggaggctgaggtaggagaattgcttgaacccaggagacagaggctgcattgagccaagatcacaccactgcactccagcctgggcagcagagcaagactccatctcaaaaaaaaaaaaaagaaaaagaaaaagaaggttaatccttcagttatggaggtgggatgaatagagcttgtttgatgttaaagtgggtaaggagggagtggccttgagacacttgtattccaaactctcctggaggtttccagtagcactactgttcctaaaagggtttcatttttaacttcatctgttttgttaacatccagtccaattgaggtgatctcagaggtgcatcaggacatctagcactggggaggccaccttgcccagatagttgaaaagaaaattggtctgggcagcctgttgtcttttgtcttcatgtaatgttttttctttgttttaaaggactaatgtttattacagtgttaaataaaagtgtaagatactaagtgtgtagaataaaagtgcaataacaaaagacaatgactttggcacacacttcagtctttatcctctctcctttcttgtgctacctggctctttccataatattgttacagcaggaccgtcttaattgtgtgcattttgaagagatgcgactctgggttaatcttcattagtgtaatattgaagggttgggtttggttttatagagtattctgtatacttgttgggatacacaaataccagatgtgctgtataataaagatcacattaacgttttaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:25778 -> Molecular function: GO:0004674 [protein serine/threonine kinase activity] evidence: IEA
GeneID:25778 -> Molecular function: GO:0004712 [protein serine/threonine/tyrosine kinase activity] evidence: IEA
GeneID:25778 -> Molecular function: GO:0004713 [protein tyrosine kinase activity] evidence: IEA
GeneID:25778 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:25778 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:25778 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:25778 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA
GeneID:25778 -> Cellular component: GO:0045111 [intermediate filament cytoskeleton] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_955749 -> EC 2.7.12.1
by
@meso_cacase at
DBCLS
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