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2025-05-09 17:27:12, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_198976 2320 bp mRNA linear PRI 01-MAY-2013
DEFINITION Homo sapiens negative elongation factor complex member C/D
(NELFCD), mRNA.
ACCESSION NM_198976
VERSION NM_198976.2 GI:399788585
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2320)
AUTHORS Wu,W., Sun,Z., Wu,J., Peng,X., Gan,H., Zhang,C., Ji,L., Xie,J.,
Zhu,H., Ren,S., Gu,J. and Zhang,S.
TITLE Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK
signaling and cell migration
JOURNAL PLoS ONE 7 (1), E29920 (2012)
PUBMED 22238675
REMARK GeneRIF: Trihydrophobin 1 phosphorylation by c-Src regulates
MAPK/ERK signaling and cell migration.
REFERENCE 2 (bases 1 to 2320)
AUTHORS Zou,W., Yang,Y., Wu,Y., Sun,L., Chi,Y., Wu,W., Yun,X., Xie,J. and
Gu,J.
TITLE Negative role of trihydrophobin 1 in breast cancer growth and
migration
JOURNAL Cancer Sci. 101 (10), 2156-2162 (2010)
PUBMED 20735431
REMARK GeneRIF: TH1 might play an important role in regulation of
proliferation and invasion in human breast cancer.
REFERENCE 3 (bases 1 to 2320)
AUTHORS Yang,Y., Zou,W., Kong,X., Wang,H., Zong,H., Jiang,J., Wang,Y.,
Hong,Y., Chi,Y., Xie,J. and Gu,J.
TITLE Trihydrophobin 1 attenuates androgen signal transduction through
promoting androgen receptor degradation
JOURNAL J. Cell. Biochem. 109 (5), 1013-1024 (2010)
PUBMED 20069563
REMARK GeneRIF: These results indicate that TH1 is a novel regulator to
control the duration and magnitude of androgen signal transduction
and might be directly involved in androgen-related developmental,
physiological, and pathological processes.
REFERENCE 4 (bases 1 to 2320)
AUTHORS Sun,J. and Li,R.
TITLE Human negative elongation factor activates transcription and
regulates alternative transcription initiation
JOURNAL J. Biol. Chem. 285 (9), 6443-6452 (2010)
PUBMED 20028984
REMARK GeneRIF: diverse transcriptional consequence of NELF-mediated
RNAPII pausing in the human genome
REFERENCE 5 (bases 1 to 2320)
AUTHORS Pal,P., Mihanovic,M., Molnar,S., Xi,H., Sun,G., Guha,S., Jeran,N.,
Tomljenovic,A., Malnar,A., Missoni,S., Deka,R. and Rudan,P.
TITLE Association of tagging single nucleotide polymorphisms on 8
candidate genes in dopaminergic pathway with schizophrenia in
Croatian population
JOURNAL Croat. Med. J. 50 (4), 361-369 (2009)
PUBMED 19673036
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 2320)
AUTHORS Yin,X.L., Chen,S. and Gu,J.X.
TITLE Identification of TH1 as an interaction partner of A-Raf kinase
JOURNAL Mol. Cell. Biochem. 231 (1-2), 69-74 (2002)
PUBMED 11952167
REMARK GeneRIF: In a two-hybrid screen of human fetal liver cDNA library,
TH1 was detected as a new interaction partner of A-Raf; this
specific interaction may have played a critical role in the
activation of A-Raf.
REFERENCE 7 (bases 1 to 2320)
AUTHORS Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
Rogers,J.
TITLE The DNA sequence and comparative analysis of human chromosome 20
JOURNAL Nature 414 (6866), 865-871 (2001)
PUBMED 11780052
REFERENCE 8 (bases 1 to 2320)
AUTHORS Ping,Y.H. and Rana,T.M.
TITLE DSIF and NELF interact with RNA polymerase II elongation complex
and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA
polymerase II and DSIF during transcription elongation
JOURNAL J. Biol. Chem. 276 (16), 12951-12958 (2001)
PUBMED 11112772
REFERENCE 9 (bases 1 to 2320)
AUTHORS Bonthron,D.T., Hayward,B.E., Moran,V. and Strain,L.
TITLE Characterization of TH1 and CTSZ, two non-imprinted genes
downstream of GNAS1 in chromosome 20q13
JOURNAL Hum. Genet. 107 (2), 165-175 (2000)
PUBMED 11030415
REFERENCE 10 (bases 1 to 2320)
AUTHORS Yamaguchi,Y., Takagi,T., Wada,T., Yano,K., Furuya,A., Sugimoto,S.,
Hasegawa,J. and Handa,H.
TITLE NELF, a multisubunit complex containing RD, cooperates with DSIF to
repress RNA polymerase II elongation
JOURNAL Cell 97 (1), 41-51 (1999)
PUBMED 10199401
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from HY015074.1, AK293410.1 and
BQ022435.1.
On Aug 8, 2012 this sequence version replaced gi:39812491.
Summary: The NELF complex of proteins interacts with the DSIF
protein complex to repress transcriptional elongation by RNA
polymerase II. The protein encoded by this gene is an essential
part of the NELF complex. Alternative translation initiation site
usage results in the formation of two isoforms with different
N-termini. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC014952.1, AJ238379.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-48 HY015074.1 2-49
49-2179 AK293410.1 1-2131
2180-2320 BQ022435.1 1-141 c
FEATURES Location/Qualifiers
source 1..2320
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20q13"
gene 1..2320
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/note="negative elongation factor complex member C/D"
/db_xref="GeneID:51497"
/db_xref="HGNC:15934"
/db_xref="MIM:605297"
exon 1..162
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 33
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:151333"
CDS 49..1848
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/note="TH1 drosophila homolog; trihydrophobin 1; negative
elongation factor proteins C and D; NELF-C/D; TH1-like
protein"
/codon_start=1
/product="negative elongation factor C/D"
/protein_id="NP_945327.2"
/db_xref="GI:399788586"
/db_xref="CCDS:CCDS13473.2"
/db_xref="GeneID:51497"
/db_xref="HGNC:15934"
/db_xref="MIM:605297"
/translation="
MRRARSREGMAGAVPGAIMDEDYYGSAAEWGDEADGGQQEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRIAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSKGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGARINQDHKHKYIHILAYAASVVETWKKNKRVSINKDELKSTSKAVETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKTEGEHDPVTEFIAHCKSNFIMVN
"
misc_feature 202..1842
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/note="TH1 protein; Region: TH1; pfam04858"
/db_xref="CDD:147160"
misc_feature 103..105
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/note="translation initiation codon of NELF-D isoform"
variation 141
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:375172251"
exon 163..278
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 168
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:200051352"
variation 207
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:376187583"
variation 217
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:143738831"
variation 229
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="g"
/replace="t"
/db_xref="dbSNP:199938188"
variation 236
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:144656284"
variation 250..251
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace=""
/replace="g"
/db_xref="dbSNP:34679405"
exon 279..388
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
exon 389..498
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 396
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:148513771"
variation 485
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:202039877"
exon 499..606
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 507
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:139317340"
variation 516
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:142656445"
variation 524
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:201652404"
variation 526
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:74557096"
variation 562
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:367744594"
variation 566
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="c"
/db_xref="dbSNP:371908338"
variation 600
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:2273360"
exon 607..759
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 618
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:142304902"
variation 631
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:368738630"
variation 657
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="c"
/db_xref="dbSNP:371873766"
variation 678
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:375217590"
variation 696
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:369321955"
variation 759
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:17851253"
exon 760..890
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 778
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="g"
/replace="t"
/db_xref="dbSNP:368991410"
variation 839
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:373372450"
variation 875
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:147835273"
exon 891..1056
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 899
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:199670127"
variation 900
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:147821977"
variation 916
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:375256983"
variation 949
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="g"
/replace="t"
/db_xref="dbSNP:61750762"
variation 975
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:368073324"
variation 990
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:148866352"
variation 1008
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:200745856"
variation 1009
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:375888011"
variation 1026
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:368566687"
variation 1047
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:372830513"
variation 1052
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="t"
/db_xref="dbSNP:375994512"
exon 1057..1191
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 1060
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="c"
/db_xref="dbSNP:150325198"
variation 1062
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:59729619"
variation 1070
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:140786664"
variation 1080
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:377766658"
variation 1086
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="c"
/db_xref="dbSNP:137872664"
variation 1104
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:35963878"
variation 1123
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="c"
/db_xref="dbSNP:143044496"
variation 1157
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:200667528"
variation 1158
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:369337569"
variation 1161
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:148160603"
variation 1162
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="g"
/replace="t"
/db_xref="dbSNP:372815228"
variation 1170
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:143108259"
exon 1192..1331
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 1200
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="c"
/db_xref="dbSNP:41276960"
variation 1202
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:188525919"
variation 1245
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:138968784"
variation 1272
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:372620907"
exon 1332..1446
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
STS 1337..1499
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/standard_name="TH1L"
/db_xref="UniSTS:505928"
variation 1380
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:368381606"
variation 1392
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:189567482"
variation 1401
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:200807638"
variation 1427
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="c"
/db_xref="dbSNP:193192"
variation 1433
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:371084351"
variation 1434
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:141996345"
exon 1447..1542
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 1450
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:150855329"
variation 1468
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:6123843"
variation 1473
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:139324271"
variation 1478
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:149977485"
variation 1506
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:144257648"
variation 1530
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:372330781"
variation 1533
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:376830862"
exon 1543..1683
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 1549
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="g"
/replace="t"
/db_xref="dbSNP:373208083"
variation 1584
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:374913633"
variation 1615
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:140598361"
variation 1642
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:369278623"
variation 1646
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="t"
/db_xref="dbSNP:144525220"
variation 1668
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:200887618"
variation 1677
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:141353754"
exon 1684..1813
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 1684
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:370660207"
variation 1692
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:113105477"
variation 1705
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:367687877"
variation 1722
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:371935126"
variation 1727
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:142546785"
variation 1728
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:368757097"
variation 1761
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:150954057"
variation 1767
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="t"
/db_xref="dbSNP:188308685"
variation 1779
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:113490649"
variation 1786
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:150087382"
exon 1814..2305
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/inference="alignment:Splign:1.39.8"
variation 1834
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:374163096"
variation 1837
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:138548641"
variation 1862
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:201888062"
variation 1892
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:368311400"
variation 1893
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:372607429"
variation 1903
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace=""
/replace="a"
/db_xref="dbSNP:71754390"
variation 1933
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="g"
/replace="t"
/db_xref="dbSNP:7341"
variation 1977
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:1043219"
variation 1998
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:182559465"
variation 2002
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:11542235"
STS 2024..2261
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/standard_name="A004R34"
/db_xref="UniSTS:40603"
variation 2027
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="c"
/db_xref="dbSNP:371727543"
variation 2050
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:184888819"
variation 2055
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="g"
/db_xref="dbSNP:3182973"
variation 2077
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace=""
/replace="t"
/db_xref="dbSNP:71743473"
variation 2099
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="t"
/db_xref="dbSNP:189775868"
variation 2127
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="c"
/replace="g"
/db_xref="dbSNP:111278153"
STS 2165..2292
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/standard_name="SHGC-31778"
/db_xref="UniSTS:47319"
variation 2205
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
/replace="a"
/replace="t"
/db_xref="dbSNP:375356368"
polyA_site 2285
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
polyA_site 2305
/gene="NELFCD"
/gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
ORIGIN
gaggcgcgcggccgcgcgtgcgcccgcccgcccgtccccgcctcgcgcatgcgccgcgctcgctcgcgggagggcatggcgggggccgtgccgggcgccatcatggacgaggactactacgggagcgcggccgagtggggcgacgaggctgacggcggccagcaggaggatgattctggagaaggagaggatgatgcggaggttcagcaagaatgcctgcataaattttccacccgggattatatcatggaaccctccatcttcaacactctgaagaggtattttcaggcaggagggtctccagagaatgttatccagctcttatctgaaaactacaccgctgtggcccagactgtgaacctgctggccgagtggctcattcagacaggtgttgagccagtgcaggttcaggaaactgtggaaaatcacttgaagagtttgctgatcaaacattttgacccccgcaaagcagattctatttttactgaagaaggagagaccccagcgtggctggaacagatgattgcacataccacgtggcgggaccttttttataaactggctgaagcccatccagactgtttgatgctgaacttcaccgttaagcttatttctgacgcagggtaccagggggagatcaccagtgtgtccacagcatgccagcagctagaagtgttctcgagagtgctccggacctctctagctacaattttagatggaggagaagaaaaccttgaaaaaaatctccctgagtttgccaagatggtgtgccacggggagcacacgtacctgtttgcccaggccatgatgtccgtgctggcccaggaggagcaggggggctccgctgtgcgcaggatcgcccaggaagtgcagcgctttgcccaggagaaaggtcatgacgccagtcagatcacactagccttgggcacagctgcctcctaccccagggcctgccaggctctcggggccatgctgtccaaaggagccctgaaccctgctgacatcaccgtcctgttcaagatgttcacaagcatggaccctcctccggttgaacttatccgcgttccagccttcctggacctgttcatgcagtcactctttaaaccaggggctcggatcaaccaggaccacaagcacaaatacatccacatcttggcgtacgcagcaagcgtggttgagacctggaagaagaacaagcgagtgagcatcaataaagatgagctgaagtcaacgtcaaaagctgtcgaaaccgttcacaatttgtgttgcaacgagaacaaaggggcctctgaactagtggcagaattgagcacactttatcagtgtattaggtttccagtggtagcaatgggtgtgctgaagtgggtggattggactgtatcagaaccaaggtactttcagctgcagactgaccatacccctgtccacctggcgttgctggatgagatcagcacctgccaccagctcctgcacccccaggtcctgcagctgcttgttaagctttttgagactgagcactcccagctggacgtgatggagcagcttgagttgaagaagacactgctggacaggatggttcacctgctgagtcgaggttatgtacttcctgttgtcagttacatccgaaagtgtctggagaagctggacactgacatttcactcattcgctattttgtcactgaggtgctggacgtcattgctcctccttatacctctgacttcgtgcaacttttcctccccatcctggagaatgacagcatcgcaggtaccatcaaaacggaaggcgagcatgaccctgtgacggagtttatagctcactgcaaatctaacttcatcatggtgaactaatttagagcatcctccagagctgaagcagaacattccagaacccgttgtggaaaaaccctttcaagaagctgttttaagaggctcgggcagcgtcttgaaaatgggcaccgctgggaggaggtggatgacttctttacaaaggaaaatggtagcagcttcagtgagaaactgcccttacaaacagtcccttctctgctgtcaatccaatactgctcccaaatcctgttttcagtgttcatttccctcaaggcaggcgctgggctcccacgacccctcaggacagatctggccgtcagccgcgggccgctgggaactccactcggggaactcctttccaagctgacctcagttttctcacaagaacccagttagctgatgttttattgtaattgtcttaatttgctaagaacaagtaataagtaaatttttaaaaagcctttctgctgggttggattaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:51497 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:51497 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
GeneID:51497 -> Biological process: GO:0006368 [transcription elongation from RNA polymerase II promoter] evidence: TAS
GeneID:51497 -> Biological process: GO:0010467 [gene expression] evidence: TAS
GeneID:51497 -> Biological process: GO:0016032 [viral process] evidence: TAS
GeneID:51497 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IEA
GeneID:51497 -> Biological process: GO:0050434 [positive regulation of viral transcription] evidence: TAS
GeneID:51497 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:51497 -> Cellular component: GO:0032021 [NELF complex] evidence: IDA
by
@meso_cacase at
DBCLS
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