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2025-05-09 17:02:33, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_173079 3844 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens RUN domain containing 1 (RUNDC1), mRNA.
ACCESSION NM_173079
VERSION NM_173079.2 GI:171543849
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3844)
AUTHORS Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
TITLE A germline-specific class of small RNAs binds mammalian Piwi
proteins
JOURNAL Nature 442 (7099), 199-202 (2006)
PUBMED 16751776
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DC391927.1, BC014873.1, AY189284.1, CA445450.1, AL831813.1 and
BC039247.1.
On Apr 1, 2008 this sequence version replaced gi:27436874.
##Evidence-Data-START##
Transcript exon combination :: BC039247.1, AL831813.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025085 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-6 DC391927.1 1-6
7-867 BC014873.1 1-861
868-870 AY189284.1 853-855
871-2163 BC014873.1 862-2154
2164-2363 AY189284.1 2149-2348
2364-2724 CA445450.1 1-361 c
2725-3820 AL831813.1 2713-3808
3821-3844 BC039247.1 3825-3848
FEATURES Location/Qualifiers
source 1..3844
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21.31"
gene 1..3844
/gene="RUNDC1"
/note="RUN domain containing 1"
/db_xref="GeneID:146923"
/db_xref="HGNC:25418"
exon 1..510
/gene="RUNDC1"
/inference="alignment:Splign:1.39.8"
variation 5
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:372010788"
CDS 13..1854
/gene="RUNDC1"
/codon_start=1
/product="RUN domain-containing protein 1"
/protein_id="NP_775102.2"
/db_xref="GI:171543850"
/db_xref="CCDS:CCDS11448.1"
/db_xref="GeneID:146923"
/db_xref="HGNC:25418"
/translation="
MAAVEAAAEPVTVVAAVGPKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEATAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTGGGHCECKAGGKTGNGCSRTGSSRTPPGNSKTKAEDVKKVRETGLHLMRRALAVLQIFAVSQFGCATGQIPPTLWQRVQADRDYSPLLKRLEVSVDRVKQLALRQQPHDHVITSANLQDLSLGGKDELTMAVRKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPVTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF
"
misc_feature 172..174
/gene="RUNDC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q96C34.3); phosphorylation site"
misc_feature 223..225
/gene="RUNDC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q96C34.3); phosphorylation site"
misc_feature 235..237
/gene="RUNDC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q96C34.3); phosphorylation site"
misc_feature 1297..1752
/gene="RUNDC1"
/note="RUN domain; Region: RUN; pfam02759"
/db_xref="CDD:190411"
variation 22
/gene="RUNDC1"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:17853899"
variation 25
/gene="RUNDC1"
/replace="g"
/replace="t"
/db_xref="dbSNP:372920205"
variation 29
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199576891"
variation 39
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376633797"
variation 41
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201536677"
variation 63
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374885370"
variation 127
/gene="RUNDC1"
/replace="a"
/replace="c"
/db_xref="dbSNP:369316147"
variation 135
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:111480415"
variation 141
/gene="RUNDC1"
/replace="g"
/replace="t"
/db_xref="dbSNP:17853898"
variation 153
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372831938"
variation 191
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:144065038"
variation 214
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:28584166"
variation 424
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:552222"
variation 490
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:1708875"
exon 511..669
/gene="RUNDC1"
/inference="alignment:Splign:1.39.8"
variation 531
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369497685"
variation 533
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:34886583"
variation 556
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377394528"
variation 557
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200463952"
variation 581
/gene="RUNDC1"
/replace="a"
/replace="c"
/db_xref="dbSNP:370774883"
variation 598
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:150170620"
variation 635
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199867848"
variation 636
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138665314"
variation 649
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371790855"
exon 670..868
/gene="RUNDC1"
/inference="alignment:Splign:1.39.8"
variation 692
/gene="RUNDC1"
/replace="a"
/replace="c"
/db_xref="dbSNP:368796436"
variation 719
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:55637973"
variation 753
/gene="RUNDC1"
/replace="g"
/replace="t"
/db_xref="dbSNP:375224265"
variation 754
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:149556177"
variation 755
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371936857"
variation 781
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:202076807"
variation 841
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375923988"
variation 857
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376014187"
exon 869..988
/gene="RUNDC1"
/inference="alignment:Splign:1.39.8"
variation 874
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146074807"
variation 879
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200074053"
variation 922
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:375924857"
variation 957
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376140938"
variation 968
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200178797"
exon 989..3828
/gene="RUNDC1"
/inference="alignment:Splign:1.39.8"
variation 1015
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199952607"
variation 1023
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368913304"
variation 1026
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61995865"
variation 1032
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376515632"
variation 1039
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200561980"
variation 1040
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374188538"
variation 1053
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:142045600"
variation 1109
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377624220"
variation 1168
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:61995866"
variation 1201
/gene="RUNDC1"
/replace="a"
/replace="t"
/db_xref="dbSNP:17857183"
variation 1233
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371346358"
variation 1279
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376046963"
variation 1304
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367817542"
variation 1311
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139713888"
variation 1321
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:61995864"
variation 1338
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:151110762"
variation 1370
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368096797"
variation 1384
/gene="RUNDC1"
/replace="g"
/replace="t"
/db_xref="dbSNP:200110770"
variation 1411
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200042329"
variation 1440
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371530871"
variation 1454
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140037579"
variation 1464
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370262164"
variation 1531
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:145831322"
variation 1535
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372331738"
variation 1550
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:74586760"
variation 1569
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200841189"
variation 1613
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200217728"
variation 1631
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:369376117"
variation 1648
/gene="RUNDC1"
/replace="a"
/replace="c"
/db_xref="dbSNP:375833434"
variation 1661
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147773660"
variation 1670
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:141180839"
variation 1695
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112582719"
variation 1708
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:3744241"
variation 1709
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147605440"
variation 1726..1727
/gene="RUNDC1"
/replace=""
/replace="g"
/db_xref="dbSNP:35176532"
variation 1777
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375753180"
variation 1778
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369271006"
variation 1786
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:113828381"
variation 1836
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:369542823"
variation 1865
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201943128"
variation 1891
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:368354222"
variation 1896
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:116930490"
variation 1908
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:76551330"
variation 1930
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:148971671"
variation 1981
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:55857539"
variation 2026
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142985946"
variation 2079
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373428200"
variation 2119
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:9892750"
STS 2138..2608
/gene="RUNDC1"
/standard_name="D10S16"
/db_xref="UniSTS:155756"
variation 2148
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377702502"
STS 2172..2275
/gene="RUNDC1"
/standard_name="D8S2278"
/db_xref="UniSTS:473906"
STS 2177..2621
/gene="RUNDC1"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 2177..2267
/gene="RUNDC1"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 2225..2307
/gene="RUNDC1"
/standard_name="L18426"
/db_xref="UniSTS:34648"
STS 2227..2683
/gene="RUNDC1"
/standard_name="D11S2921"
/db_xref="UniSTS:152074"
STS 2227..2329
/gene="RUNDC1"
/standard_name="D11S2921"
/db_xref="UniSTS:152074"
STS 2233..2322
/gene="RUNDC1"
/standard_name="PMC156606P1"
/db_xref="UniSTS:271408"
variation 2279
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:151103662"
variation 2292
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:188431533"
STS 2327..2454
/gene="RUNDC1"
/standard_name="L17809"
/db_xref="UniSTS:39087"
variation 2347
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:140940513"
variation 2350
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112587618"
variation 2353
/gene="RUNDC1"
/replace="a"
/replace="c"
/db_xref="dbSNP:77608010"
variation 2486
/gene="RUNDC1"
/replace="a"
/replace="c"
/db_xref="dbSNP:180796423"
STS 2494..2608
/gene="RUNDC1"
/standard_name="D10S16"
/db_xref="UniSTS:155756"
variation 2509
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146446897"
STS 2533..2621
/gene="RUNDC1"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
variation 2568
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:185820028"
variation 2613
/gene="RUNDC1"
/replace="g"
/replace="t"
/db_xref="dbSNP:189786"
variation 2631
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:117577073"
variation 2668
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:2667943"
variation 2706..2707
/gene="RUNDC1"
/replace=""
/replace="a"
/db_xref="dbSNP:375882614"
variation 2730
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201072724"
variation 2730
/gene="RUNDC1"
/replace=""
/replace="g"
/db_xref="dbSNP:370572471"
variation 2803
/gene="RUNDC1"
/replace="g"
/replace="t"
/db_xref="dbSNP:111518806"
variation 2834
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:188773171"
variation 2862
/gene="RUNDC1"
/replace="g"
/replace="t"
/db_xref="dbSNP:141682294"
variation 2941
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:147053600"
variation 3013
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:692237"
variation 3176
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368088390"
variation 3180
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138047102"
variation 3218
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:181158419"
variation 3244..3245
/gene="RUNDC1"
/replace=""
/replace="g"
/db_xref="dbSNP:368867699"
variation 3255
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149498383"
STS 3331..3480
/gene="RUNDC1"
/standard_name="SHGC-32804"
/db_xref="UniSTS:45691"
variation 3331
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:377760386"
STS 3337..3474
/gene="RUNDC1"
/standard_name="RH47209"
/db_xref="UniSTS:92111"
variation 3342
/gene="RUNDC1"
/replace="a"
/replace="c"
/db_xref="dbSNP:187015312"
variation 3386
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:191397823"
variation 3397
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:184243517"
variation 3417
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:491519"
variation 3507
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:144154500"
variation 3533
/gene="RUNDC1"
/replace="a"
/replace="t"
/db_xref="dbSNP:374502540"
variation 3558
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:1043281"
variation 3591
/gene="RUNDC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:72826999"
variation 3648
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:1043284"
variation 3671
/gene="RUNDC1"
/replace="g"
/replace="t"
/db_xref="dbSNP:186221579"
variation 3751
/gene="RUNDC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:691988"
variation 3755
/gene="RUNDC1"
/replace="a"
/replace="g"
/db_xref="dbSNP:691987"
polyA_site 3820
/gene="RUNDC1"
ORIGIN
gtttccgggaagatggcggctgtcgaagcggctgcagagccggtaacggtggtggcggctgttgggccaaaggcgaaagacgaagaggaggaggaagaggagccgctgccaccgtgcgaggcggtgcgctgggccccagtgggggcggtggcggaggcccggcctggggcaaccgcgtttttagaagaggcgacggccgaggagcctggcgcggccccgggctccccgccggattcgccgggccggacgctgcggcggctgcgggcagagcggcggcggctggactcggcgctgctggcgctgtcctcgcacttcgcgcaggtgcagttccgcctgcgccaggtggtgcgcggggcgccggcggagcagcagcgccttctgcgggagctcgaagacttcgccttccgcggctgccctcacgtcctaggttacgaagggcccggcgaccccgccagcgatgagggcgatgggctgccaggggaccggccacggttgcggggcgaggaccagagtgagcaggaaaagcaagagcgtctggaaacccaaagggagaagcagaaagaactgatactgcagctcaagacccagctagatgacctggaaacgtttgcctatcaagagggcagttatgactcgctgccacagtccgtggtgttggaaagacagcgggtgatcatagatgagttaataaagaaactggacatgaatctgaatgaggacatcagttccctgtccactgaagagcttcgtcagcgtgtagatgcagcagtggctcagatcgtcaacccagcccgagtcaaagaacagttggttgagcaactgaaaactcagatccgagaccttgagatgtttatcaacttcatccaagatgaagtgggaagccccttgcagacaggtggtggacactgtgagtgcaaggccggtgggaagacaggaaatggctgcagcagaacaggcagcagcagaacgcctccaggaaacagcaaaacaaaggcagaggatgtgaagaaagtccgggagacggggctgcacctgatgcggcgagcgctggccgtgctccagatctttgctgttagccagtttggttgtgccacaggccagatccctccaaccctgtggcagagggtccaggctgacagagactactctcccttgctgaagaggctggaggtgtcagtggacagagtgaagcagctagccttgaggcagcagccacatgaccatgtcatcacctctgccaacctccaggacctctctctgggaggcaaggatgagctgactatggctgtgcggaaggagctaacggtggctgtgagggacctgctggcccatggactgtatgcctcctccccagggatgagccttgttatggctcctattgcttgtttgctgccagccttctcctcggccccagaggccatgcacccgtgggagctctttgtaaagtactaccatgctaagaacggccgtgcttatgtggaatccccagcccggaagctctcccagtccttcgcccttcctgttacgggaggcactgttgtcacccccaaacagagcctactgacagccatccacatggtgctgacagagcatgacccttttaagcgcagtgcagactcagaattgaaggccttggtgtgcatggcactgaatgagcagcgtctggtgtcctgggtgaacctcatctgcaagtccgggtcactcatcgagcctcactaccagccctggagctacatggcacacacaggctttgagagtgccctcaacctgctcagtcgcctcagcagcctcaagtttagcctccctgtagatctggctgtgcgccagctcaaaaacatcaaagatgccttttgatgagagtgccctaaccccagacaagctccttgttcagtagggatagatgtgctagtcttctagcataggagcaaggaatcagaggtggggttaaaggcatttttcccagaccctgctcaggcagtcggccaaatgagtgcaaagtctgttttccccaccaacttagctctcggaaagatgtgctggagggaccctcttgttaagaaggttctgccaggccgggcgcggtggctcacacctgtaatcccagcactttgggaggccgaggcgggcggatcacaaggtcaggagttcgagaccatcctgtctaacacggtgaaaccccatctctactaaaaatacaaaaaaattagtcggacatggtggcaggcacctgtagtcccagctactcgggaggctgaggcaggagaatggcgtgaacccaggaggcggagcttgcagtgagccaagatcgcgccactgcactccagcctgggcgacagagtgagactccgtctcaaaaaaaaaaagaaggttgtacccacagtatacgtgtgggcacttgtgcttgagcctgtattaaaggaatcaggccaggcacagtggctcacgcctgtaatctcagcacattgggaggctgaggtgggcggatcacctgaggtcaggagttcaagaccagcctggccaacatggtgaaaccccatctctactaaaaatacaaaaattagctaggcggggtagtgcatgcctgtaatcccagctactcaggaggctgaggccggagaatcgcttgagcccgagaggtggagactgcagtaagccaagatcatgccactgcactccagcctgggcaacacagggagactccatctcaaaaaaaaaaaaaaaaaaaaaaagacattcaacttgaggctcctgttagttaagctatcttctttcacttgaagcaggtttgagaggcctaggccagaatttaaattccttttatgaatagatttccctttcttcctgaccccaaggtcagaggagactatatattccatggctgcctctaagactaggaataggaatatctgaaaacagcatttctaagggtggtaaccacaggtcgattttaatacgagtcctttttcttgtagaggtaagtaaaatcttcctgacaaggtagtcctcttttcacggcacagacaatgggctttctgtttatgaggggtgagaagtgatgtttgttactatgttctccagcaagtaaacattcctctgctcacctcccaacaagactaacagtctttttagaagtaaatatattcaagacaaacgagaaaatcctggctacccaagtcgagtatatacaggaatacaaatcggtaaccagcagctgttcctcaggttgtgactcactgagcaccacttgtcctggaggctggatgatggaggacatctggttataggtactgtagcagggataggtgccacaggaggataggaactacagcagatcgctgtttccagaacggggaggagtatctcattgtgaaacagactctagagtggttctatttggtcttcagtgttttagcctcattagttcatatttggcatgcagcttgtggtgagtactgttctaggactggccaaaaatgggcaaaatgtatcactccaaacactactgattcagcattgttttcatgtcttaaaattgccacctgcactttgtttctgcactattatgtagtgcattttaacttaaattttttccagcaacatgttacttatttaagatacattactgatatttcattataattagttcaccttccctgtgaaacaagagaattgtaaaatgttgtggaaaatgatacatatgtggatgctaatgaaatcatagtattttgtgtagcttctctgaagaccttagagacctgcagctttggtttataagtgtttgggccttatcagcccatctgatccagatcaatatttttttgaaaactgaaaaaaaaaaaaaaaa
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