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2025-05-09 16:59:53, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_025235 6274 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 (TNKS2), mRNA.
ACCESSION NM_025235
VERSION NM_025235.3 GI:197927276
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6274)
AUTHORS Kang,H.W., Wang,F., Wei,Q., Zhao,Y.F., Liu,M., Li,X. and Tang,H.
TITLE miR-20a promotes migration and invasion by regulating TNKS2 in
human cervical cancer cells
JOURNAL FEBS Lett. 586 (6), 897-904 (2012)
PUBMED 22449978
REMARK GeneRIF: Data suggest that miR-20a can promote migration and
invasion of cervical cancer cells through the upregulation of
TNKS2.
REFERENCE 2 (bases 1 to 6274)
AUTHORS Guettler,S., LaRose,J., Petsalaki,E., Gish,G., Scotter,A.,
Pawson,T., Rottapel,R. and Sicheri,F.
TITLE Structural basis and sequence rules for substrate recognition by
Tankyrase explain the basis for cherubism disease
JOURNAL Cell 147 (6), 1340-1354 (2011)
PUBMED 22153077
REMARK GeneRIF: Study reports crystal structures of a representative
ankyrin repeat clusters of TNKS2 bound to targeting peptides from
six substrates.
Erratum:[Cell. 2012 Jan 20;148(1-2):376]
REFERENCE 3 (bases 1 to 6274)
AUTHORS Casabonne,D., Reina,O., Benavente,Y., Becker,N., Maynadie,M.,
Foretova,L., Cocco,P., Gonzalez-Neira,A., Nieters,A., Boffetta,P.,
Middeldorp,J.M. and de Sanjose,S.
TITLE Single nucleotide polymorphisms of matrix metalloproteinase 9
(MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus
in chronic lymphocytic leukemia: results from the European
case-control study EpiLymph
JOURNAL Haematologica 96 (2), 323-327 (2011)
PUBMED 21048031
REMARK GeneRIF: Observational study of gene-disease association and
gene-environment interaction. (HuGE Navigator)
REFERENCE 4 (bases 1 to 6274)
AUTHORS Zee,R.Y., Ridker,P.M. and Chasman,D.I.
TITLE Genetic variants in eleven telomere-associated genes and the risk
of incident cardio/cerebrovascular disease: The Women's Genome
Health Study
JOURNAL Clin. Chim. Acta 412 (1-2), 199-202 (2011)
PUBMED 20937264
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 5 (bases 1 to 6274)
AUTHORS Callow,M.G., Tran,H., Phu,L., Lau,T., Lee,J., Sandoval,W.N.,
Liu,P.S., Bheddah,S., Tao,J., Lill,J.R., Hongo,J.A., Davis,D.,
Kirkpatrick,D.S., Polakis,P. and Costa,M.
TITLE Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt
signaling
JOURNAL PLoS ONE 6 (7), E22595 (2011)
PUBMED 21799911
REMARK GeneRIF: RNF146 RING-type ubiquitin E3 ligase as a positive
regulator of Wnt signaling that operates with tankyrase to maintain
low steady-state levels of Axin proteins
REFERENCE 6 (bases 1 to 6274)
AUTHORS Cook,B.D., Dynek,J.N., Chang,W., Shostak,G. and Smith,S.
TITLE Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2
at human telomeres
JOURNAL Mol. Cell. Biol. 22 (1), 332-342 (2002)
PUBMED 11739745
REFERENCE 7 (bases 1 to 6274)
AUTHORS Kaminker,P.G., Kim,S.H., Taylor,R.D., Zebarjadian,Y., Funk,W.D.,
Morin,G.B., Yaswen,P. and Campisi,J.
TITLE TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes
rapid induction of cell death upon overexpression
JOURNAL J. Biol. Chem. 276 (38), 35891-35899 (2001)
PUBMED 11454873
REFERENCE 8 (bases 1 to 6274)
AUTHORS Lyons,R.J., Deane,R., Lynch,D.K., Ye,Z.S., Sanderson,G.M.,
Eyre,H.J., Sutherland,G.R. and Daly,R.J.
TITLE Identification of a novel human tankyrase through its interaction
with the adaptor protein Grb14
JOURNAL J. Biol. Chem. 276 (20), 17172-17180 (2001)
PUBMED 11278563
REFERENCE 9 (bases 1 to 6274)
AUTHORS Kuimov,A.N., Kuprash,D.V., Petrov,V.N., Vdovichenko,K.K.,
Scanlan,M.J., Jongeneel,C.V., Lagarkova,M.A. and Nedospasov,S.A.
TITLE Cloning and characterization of TNKL, a member of tankyrase gene
family
JOURNAL Genes Immun. 2 (1), 52-55 (2001)
PUBMED 11294570
REFERENCE 10 (bases 1 to 6274)
AUTHORS Monz,D., Munnia,A., Comtesse,N., Fischer,U., Steudel,W.I.,
Feiden,W., Glass,B. and Meese,E.U.
TITLE Novel tankyrase-related gene detected with meningioma-specific sera
JOURNAL Clin. Cancer Res. 7 (1), 113-119 (2001)
PUBMED 11205898
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AF438201.1, AF309033.1 and BQ019749.1.
On Sep 4, 2008 this sequence version replaced gi:21361945.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF438201.1, AF309033.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025083 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-2657 AF438201.1 83-2739
2658-6074 AF309033.1 2612-6028
6075-6274 BQ019749.1 18-217 c
FEATURES Location/Qualifiers
source 1..6274
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q23.3"
gene 1..6274
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="tankyrase, TRF1-interacting ankyrin-related
ADP-ribose polymerase 2"
/db_xref="GeneID:80351"
/db_xref="HGNC:15677"
/db_xref="HPRD:06182"
/db_xref="MIM:607128"
exon 1..496
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 8..9
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="ggagctggca"
/db_xref="dbSNP:148775233"
variation 9..10
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="ggagctggca"
/db_xref="dbSNP:71959546"
variation 22..23
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="ctggcaggag"
/db_xref="dbSNP:59118225"
variation 70
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:138273949"
variation 105
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:149184100"
variation 239
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:190428414"
CDS 298..3798
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/EC_number="2.4.2.30"
/note="tankyrase 2; TNKS-2; tankyrase II; tankyrase-like
protein; tankyrase-related protein; poly [ADP-ribose]
polymerase 5B; TRF1-interacting ankyrin-related ADP-ribose
polymerase 2; ADP-ribosyltransferase diphtheria toxin-like
6"
/codon_start=1
/product="tankyrase-2"
/protein_id="NP_079511.1"
/db_xref="GI:13376842"
/db_xref="CCDS:CCDS7417.1"
/db_xref="GeneID:80351"
/db_xref="HGNC:15677"
/db_xref="HPRD:06182"
/db_xref="MIM:607128"
/translation="
MSGRRCAGGGAACASAAAEAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPPSALPSCYKPQVLNGVRSPGATADALSSGPSSPSSLSAASSLDNLSGSFSELSSVVSSSGTEGASSLEKKEVPGVDFSITQFVRNLGLEHLMDIFEREQITLDVLVEMGHKELKEIGINAYGHRHKLIKGVERLISGQQGLNPYLTLNTSGSGTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPEGMVDG
"
misc_feature 379..531
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="Ankyrin repeats (many copies); Region: Ank_4;
pfam13637"
/db_xref="CDD:205814"
misc_feature 445..789
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 466..564
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 1"
misc_feature 481..759
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 565..663
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 2"
misc_feature 664..762
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 3"
misc_feature 904..906
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 913..1248
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 925..1023
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 4"
misc_feature 940..1218
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 1009..1011
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyhistidine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 1024..1122
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 5"
misc_feature 1108..1110
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 1123..1221
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 6"
misc_feature 1384..1491
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 7"
misc_feature 1390..2034
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 1399..1680
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 1492..1590
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 8"
misc_feature 1576..1578
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 1591..1689
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 9"
misc_feature 1606..1965
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 1849..2214
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 1849..1851
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 1870..1968
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 10"
misc_feature 1885..2163
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 1930..1956
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: HIF1AN-binding"
misc_feature 1954..1956
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyhistidine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 1969..2067
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 11"
misc_feature 2053..2055
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 2068..2166
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 12"
misc_feature 2308..2658
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 2308..2310
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 2329..2427
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 13"
misc_feature 2344..2622
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 2413..2415
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 2428..2526
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 14"
misc_feature 2512..2514
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
hydroxylation site"
misc_feature 2527..2625
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2K2.1);
Region: ANK 15"
misc_feature 2908..3105
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="SAM domain of tankyrase1,2 subfamily; Region:
SAM_tankyrase1,2; cd09524"
/db_xref="CDD:188923"
misc_feature 2926..3099
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="SAM domain (Sterile alpha motif); Region: SAM_2;
pfam07647"
/db_xref="CDD:203706"
misc_feature 3109..3777
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/note="Tankyrases interact with the telomere reverse
transcriptase complex (TERT). Tankyrase 1
poly-ADP-ribosylates Telomere Repeat Binding Factor 1
(TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or
TRF1. The tankyrases also contain multiple ankyrin...;
Region: tankyrase_like; cd01438"
/db_xref="CDD:30069"
variation 358
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:374420951"
variation 371
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:200480328"
variation 379
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:371748408"
variation 384
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:373693017"
variation 389
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:368410431"
variation 400
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="g"
/db_xref="dbSNP:376227217"
exon 497..721
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 513
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:149057366"
variation 530
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:371801860"
variation 533
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:376514770"
variation 568
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:201518095"
variation 573
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:369816721"
variation 631
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:372595864"
variation 638
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:375628632"
variation 647
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:147839149"
variation 650
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:61756248"
variation 651
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:189629328"
variation 684
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:376748564"
variation 708
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:140299054"
exon 722..817
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 755
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:371197134"
variation 809
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:150342370"
exon 818..854
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
exon 855..930
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 861
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:138819481"
variation 868
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:145339417"
variation 895
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:149386270"
variation 912
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:145689481"
exon 931..1025
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 995
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:372097584"
exon 1026..1092
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1029
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:202102264"
variation 1075
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:200360192"
variation 1089
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:368810318"
exon 1093..1279
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1178
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:370455144"
variation 1226
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:201298866"
variation 1263
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:138258878"
exon 1280..1401
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1284
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:200034235"
variation 1296
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:193025940"
variation 1308
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:142723604"
variation 1316
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:146154837"
variation 1333
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:140168418"
variation 1350
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:141531302"
variation 1373
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:150887943"
variation 1377
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:111341432"
variation 1380
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:200935543"
variation 1399
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:369265938"
exon 1402..1493
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1413
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:201826505"
variation 1443
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:61749237"
exon 1494..1572
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1534
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:375561548"
variation 1543
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:78066006"
exon 1573..1744
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1591
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:41286934"
variation 1620
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:140304512"
variation 1622
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:202191207"
variation 1645
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:201015037"
variation 1659
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:112229271"
variation 1674
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:61756246"
variation 1695
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:200278821"
variation 1704
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:369522806"
exon 1745..1824
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1789
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:201449859"
variation 1801
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:199739075"
exon 1825..1970
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1840
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:370769267"
variation 1859
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:147855760"
variation 1861
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:201349109"
variation 1884
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:148894170"
variation 1921
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:143595087"
exon 1971..2136
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 1972
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:185509308"
variation 2047
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:12355309"
variation 2067
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:368882919"
variation 2082
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:376963141"
variation 2094
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:150996069"
exon 2137..2356
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 2295
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:140823899"
variation 2338
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:369175719"
exon 2357..2466
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 2358
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:111818851"
variation 2403
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:200916374"
variation 2463
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:376518462"
variation 2464
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:145701051"
exon 2467..2655
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 2483
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:377093087"
variation 2485
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:369439385"
variation 2536
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:373621241"
variation 2547
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:375987433"
variation 2577
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:370045797"
variation 2592
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:372597306"
exon 2656..2908
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 2658
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:3758499"
variation 2670
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:142783979"
variation 2704
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:144949883"
variation 2751
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:138704125"
variation 2772
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:73327827"
variation 2785
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:375144007"
variation 2800
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:372097848"
variation 2806
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:376200055"
variation 2822
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:145821862"
variation 2834
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:376390039"
exon 2909..2991
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 2940
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:200020202"
variation 2941
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:144839601"
variation 2961
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:373328045"
variation 2980
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:148151682"
exon 2992..3112
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 2995
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:200252145"
variation 3018
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="g"
/db_xref="dbSNP:377222592"
variation 3091
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:143952810"
variation 3103
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:147167784"
exon 3113..3210
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 3141
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:61756247"
variation 3165
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:144218813"
exon 3211..3285
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
exon 3286..3391
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 3308
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:147361517"
variation 3332
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:139013609"
variation 3371
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:370429610"
exon 3392..3578
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 3397
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:374295764"
variation 3412
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:372001710"
variation 3453
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:57058393"
variation 3469
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:145048843"
variation 3494
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:138100133"
variation 3514
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:200883409"
variation 3567
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:149086273"
variation 3576
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:199620806"
exon 3579..3735
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 3593
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:201234782"
variation 3596
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:371518074"
variation 3602
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:200094091"
variation 3659
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:75794258"
variation 3701
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:369360355"
exon 3736..6274
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/inference="alignment:Splign:1.39.8"
variation 3790
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:78123770"
variation 3799
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:146581308"
variation 3806
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:201220567"
variation 3992
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:374080423"
variation 3993..4001
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="gttttttca"
/db_xref="dbSNP:144316780"
variation 3994..4002
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="ttttttcag"
/db_xref="dbSNP:74594203"
variation 4001
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:201061571"
variation 4045
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:143819836"
variation 4073
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:184788145"
variation 4138
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:113323307"
variation 4140
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:189518244"
variation 4142
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:114508333"
variation 4271
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:147332671"
variation 4323
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:74712340"
variation 4366
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:141016151"
variation 4387
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:144863523"
variation 4414
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:180693010"
STS 4554..4744
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/standard_name="RH45093"
/db_xref="UniSTS:21412"
variation 4655
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:186084725"
variation 4701
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:190949718"
variation 4782
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:181246479"
variation 4823
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:186484885"
variation 4880
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:112017833"
variation 4946
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:190394568"
variation 5034
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:376499713"
variation 5054
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:147512282"
variation 5059
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="g"
/db_xref="dbSNP:1539042"
variation 5067
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:9633689"
variation 5107
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:41286942"
variation 5119
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:74353173"
variation 5194
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="c"
/db_xref="dbSNP:202086804"
variation 5581
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:182939246"
variation 5670
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:187567225"
variation 5714
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:2258946"
variation 5757
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:369644433"
STS 5809..6047
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/standard_name="R58932"
/db_xref="UniSTS:6050"
STS 5854..6055
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/standard_name="D10S2170"
/db_xref="UniSTS:3728"
variation 5877
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:139344799"
variation 5885..5886
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="t"
/db_xref="dbSNP:34843104"
variation 5891
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:372004441"
variation 5906
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:190903612"
variation 5948
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace=""
/replace="t"
/db_xref="dbSNP:111308061"
variation 6004
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="c"
/replace="t"
/db_xref="dbSNP:375635957"
polyA_signal 6056..6061
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
variation 6146
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="t"
/db_xref="dbSNP:149909485"
variation 6188
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:144940292"
variation 6196
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:117020425"
variation 6236
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="g"
/replace="t"
/db_xref="dbSNP:183442774"
variation 6237
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:149041264"
variation 6268
/gene="TNKS2"
/gene_synonym="ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C;
pART6; TANK2; TNKL"
/replace="a"
/replace="g"
/db_xref="dbSNP:143163793"
ORIGIN
ggctggacggagctggcaggaggggccttgccagcttccgccgccgcgtcgtttcaggacccggacggcggattcgcgctgcctccgccgccgcggggcagccggggggcagggagcccagcgaggggcgcgcgtgggcgcggccatgggactgcgccggatccggtgacagcagggagccaagcggcccgggccctgagcgcgtcttctccggggggcctcgccctcctgctcgcggggccggggctcctgctccggttgctggcgctgttgctggctgtggcggcggccaggatcatgtcgggtcgccgctgcgccggcgggggagcggcctgcgcgagcgccgcggccgaggccgtggagccggccgcccgagagctgttcgaggcgtgccgcaacggggacgtggaacgagtcaagaggctggtgacgcctgagaaggtgaacagccgcgacacggcgggcaggaaatccaccccgctgcacttcgccgcaggttttgggcggaaagacgtagttgaatatttgcttcagaatggtgcaaatgtccaagcacgtgatgatgggggccttattcctcttcataatgcatgctcttttggtcatgctgaagtagtcaatctccttttgcgacatggtgcagaccccaatgctcgagataattggaattatactcctctccatgaagctgcaattaaaggaaagattgatgtttgcattgtgctgttacagcatggagctgagccaaccatccgaaatacagatggaaggacagcattggatttagcagatccatctgccaaagcagtgcttactggtgaatataagaaagatgaactcttagaaagtgccaggagtggcaatgaagaaaaaatgatggctctactcacaccattaaatgtcaactgccacgcaagtgatggcagaaagtcaactccattacatttggcagcaggatataacagagtaaagattgtacagctgttactgcaacatggagctgatgtccatgctaaagataaaggtgatctggtaccattacacaatgcctgttcttatggtcattatgaagtaactgaacttttggtcaagcatggtgcctgtgtaaatgcaatggacttgtggcaattcactcctcttcatgaggcagcttctaagaacagggttgaagtatgttctcttctcttaagttatggtgcagacccaacactgctcaattgtcacaataaaagtgctatagacttggctcccacaccacagttaaaagaaagattagcatatgaatttaaaggccactcgttgctgcaagctgcacgagaagctgatgttactcgaatcaaaaaacatctctctctggaaatggtgaatttcaagcatcctcaaacacatgaaacagcattgcattgtgctgctgcatctccatatcccaaaagaaagcaaatatgtgaactgttgctaagaaaaggagcaaacatcaatgaaaagactaaagaattcttgactcctctgcacgtggcatctgagaaagctcataatgatgttgttgaagtagtggtgaaacatgaagcaaaggttaatgctctggataatcttggtcagacttctctacacagagctgcatattgtggtcatctacaaacctgccgcctactcctgagctatgggtgtgatcctaacattatatcccttcagggctttactgctttacagatgggaaatgaaaatgtacagcaactcctccaagagggtatctcattaggtaattcagaggcagacagacaattgctggaagctgcaaaggctggagatgtcgaaactgtaaaaaaactgtgtactgttcagagtgtcaactgcagagacattgaagggcgtcagtctacaccacttcattttgcagctgggtataacagagtgtccgtggtggaatatctgctacagcatggagctgatgtgcatgctaaagataaaggaggccttgtacctttgcacaatgcatgttcttatggacattatgaagttgcagaacttcttgttaaacatggagcagtagttaatgtagctgatttatggaaatttacacctttacatgaagcagcagcaaaaggaaaatatgaaatttgcaaacttctgctccagcatggtgcagaccctacaaaaaaaaacagggatggaaatactcctttggatcttgttaaagatggagatacagatattcaagatctgcttaggggagatgcagctttgctagatgctgccaagaagggttgtttagccagagtgaagaagttgtcttctcctgataatgtaaattgccgcgatacccaaggcagacattcaacacctttacatttagcagctggttataataatttagaagttgcagagtatttgttacaacacggagctgatgtgaatgcccaagacaaaggaggacttattcctttacataatgcagcatcttacgggcatgtagatgtagcagctctactaataaagtataatgcatgtgtcaatgccacggacaaatgggctttcacacctttgcacgaagcagcccaaaagggacgaacacagctttgtgctttgttgctagcccatggagctgacccgactcttaaaaatcaggaaggacaaacacctttagatttagtttcagcggatgatgtcagcgctcttctgacagcagccatgcccccatctgctctgccctcttgttacaagcctcaagtgctcaatggtgtgagaagcccaggagccactgcagatgctctctcttcaggtccatctagcccatcaagcctttctgcagccagcagtcttgacaacttatctgggagtttttcagaactgtcttcagtagttagttcaagtggaacagagggtgcttccagtttggagaaaaaggaggttccaggagtagattttagcataactcaattcgtaaggaatcttggacttgagcacctaatggatatatttgagagagaacagatcactttggatgtattagttgagatggggcacaaggagctgaaggagattggaatcaatgcttatggacataggcacaaactaattaaaggagtcgagagacttatctccggacaacaaggtcttaacccatatttaactttgaacacctctggtagtggaacaattcttatagatctgtctcctgatgataaagagtttcagtctgtggaggaagagatgcaaagtacagttcgagagcacagagatggaggtcatgcaggtggaatcttcaacagatacaatattctcaagattcagaaggtttgtaacaagaaactatgggaaagatacactcaccggagaaaagaagtttctgaagaaaaccacaaccatgccaatgaacgaatgctatttcatgggtctccttttgtgaatgcaattatccacaaaggctttgatgaaaggcatgcgtacataggtggtatgtttggagctggcatttattttgctgaaaactcttccaaaagcaatcaatatgtatatggaattggaggaggtactgggtgtccagttcacaaagacagatcttgttacatttgccacaggcagctgctcttttgccgggtaaccttgggaaagtctttcctgcagttcagtgcaatgaaaatggcacattctcctccaggtcatcactcagtcactggtaggcccagtgtaaatggcctagcattagctgaatatgttatttacagaggagaacaggcttatcctgagtatttaattacttaccagattatgaggcctgaaggtatggtcgatggataaatagttattttaagaaactaattccactgaacctaaaatcatcaaagcagcagtggcctctacgttttactcctttgctgaaaaaaaatcatcttgcccacaggcctgtggcaaaaggataaaaatgtgaacgaagtttaacattctgacttgataaagctttaataatgtacagtgttttctaaatatttcctgttttttcagcactttaacagatgccattccaggttaaactgggttgtctgtactaaattataaacagagttaacttgaaccttttatatgttatgcattgattctaacaaactgtaatgccctcaacagaactaattttactaatacaatactgtgttctttaaaacacagcatttacactgaatacaatttcatttgtaaaactgtaaataagagcttttgtactagcccagtatttatttacattgctttgtaatataaatctgttttagaactgcagcggtttacaaaattttttcatatgtattgttcatctatacttcatcttacatcgtcatgattgagtgatctttacatttgattccagaggctatgttcagttgttagttgggaaagattgagttatcagatttaatttgccgatgggagcctttatctgtcattagaaatctttctcatttaagaacttatgaatatgctgaagatttaatttgtgatacctttgtatgtatgagacacattccaaagagctctaactatgataggtcctgattactaaagaagcttctttactggcctcaatttctagctttcatgttggaaaattttctgcagtccttctgtgaaaattagagcaaagtgctcctgttttttagagaaactaaatcttgctgttgaacaattattgtgttcttttcatggaacataagtaggatgttacatttccagggtgggaagggtaatcctaaatcatttcccaatctattctaattaccttaaatctaaaggggaaaaaaaaaatcacaaacaggactgggtagttttttatcctaagtatattttttcctgttctttttacttggttttattgctgtatttatagccaatctatacatcatgggtaaacttaacccagaactataaaatgtagttgtctcagtcccctccaggcctcctgaatgggcaagtgcagtgaaacaggtgcttcttgctcctgggttttctctccatgatgttatgcccaattggaaatatgctgtcagtttgtgcaccatatggtgaccacgcctgtgctcagtttggcagctatagaaggaaatgctgtcccataaaatgccattcctattttctaatataaaactcttttccaggaagcatgcttaagcatcttgttacagagacatacatccattatggcttggcaatctcttttatttgttgactctagctcccttcaaagtcgaggaaagatctttactcacttaatgaggacattccccatcactgtctgtaccagttcacctttattttacgttttattcagtctgtaaattaactggccctttgcagtaacttgtacataaagtgctagaaaatcatgttccttgtcctgagtaagagttaatcagagtaaatgcatttctggagttgtttctgtgatgtaaattatgatcattatttaagaagtcaaatcctgatcttgaagtgctttttatacagctctctaataattacaaatatccgaaagtcatttcttggaacacaagtggagtatgccaaattttatatgaatttttcagattatctaagcttccaggttttataattagaagataatgagagaattaatggggtttatatttacattatctctcaactatgtagcccatattactcaccctatgagtgaatctggaattgcttttcatgtgaaatcattgtggtctatgagtttacaatactgcaaactgtgttattttatctaatccattgcttaatgagtgtgtttttccatgaatgaatataccgtggttcatatgttagcatggcagcattttcagatagctttttgtttgttgggaagttggggttttggggggagggggagtattagtacgttgcatgaaatagcttactttataatgatggaattgctttttcttttgtcttgtgatttttttttttgaagtgaaatttaactttttgtgcaagtagtactattatacccatcttcagtgtcttacttgtactgtatcacattccataccctcatttaattcttaataaaactgttcacttgtttttctgggtagcatggtaattactggaatagtataaatgtgttgaatggtctttgagaaaatgaattaagattacaataaaccacaattgcaggaaaacaatgtagttctgagtctaatagtgataaagaatgcagtttgaagtttgaaatattgaatattgtagctgtacttgctcattaaaatgaaagtagctgtga
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:80351 -> Molecular function: GO:0003950 [NAD+ ADP-ribosyltransferase activity] evidence: IDA
GeneID:80351 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:80351 -> Molecular function: GO:0019899 [enzyme binding] evidence: IPI
GeneID:80351 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
GeneID:80351 -> Biological process: GO:0000209 [protein polyubiquitination] evidence: IDA
GeneID:80351 -> Biological process: GO:0006471 [protein ADP-ribosylation] evidence: IDA
GeneID:80351 -> Biological process: GO:0016055 [Wnt receptor signaling pathway] evidence: IEA
GeneID:80351 -> Biological process: GO:0032212 [positive regulation of telomere maintenance via telomerase] evidence: IC
GeneID:80351 -> Biological process: GO:0035264 [multicellular organism growth] evidence: IEA
GeneID:80351 -> Biological process: GO:0040014 [regulation of multicellular organism growth] evidence: IEA
GeneID:80351 -> Biological process: GO:0070198 [protein localization to chromosome, telomeric region] evidence: IMP
GeneID:80351 -> Biological process: GO:0070213 [protein auto-ADP-ribosylation] evidence: IDA
GeneID:80351 -> Biological process: GO:0090263 [positive regulation of canonical Wnt receptor signaling pathway] evidence: IMP
GeneID:80351 -> Cellular component: GO:0000139 [Golgi membrane] evidence: IEA
GeneID:80351 -> Cellular component: GO:0000242 [pericentriolar material] evidence: IDA
GeneID:80351 -> Cellular component: GO:0000784 [nuclear chromosome, telomeric region] evidence: IC
GeneID:80351 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:80351 -> Cellular component: GO:0005635 [nuclear envelope] evidence: IDA
GeneID:80351 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:80351 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_079511 -> EC 2.4.2.30
by
@meso_cacase at
DBCLS
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