Home |
Help |
Advanced search
2025-05-09 16:46:15, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_004946 6117 bp mRNA linear PRI 24-JUN-2013
DEFINITION Homo sapiens dedicator of cytokinesis 2 (DOCK2), mRNA.
ACCESSION NM_004946
VERSION NM_004946.2 GI:205277317
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6117)
AUTHORS Dulak,A.M., Stojanov,P., Peng,S., Lawrence,M.S., Fox,C.,
Stewart,C., Bandla,S., Imamura,Y., Schumacher,S.E., Shefler,E.,
McKenna,A., Carter,S.L., Cibulskis,K., Sivachenko,A., Saksena,G.,
Voet,D., Ramos,A.H., Auclair,D., Thompson,K., Sougnez,C.,
Onofrio,R.C., Guiducci,C., Beroukhim,R., Zhou,Z., Lin,L., Lin,J.,
Reddy,R., Chang,A., Landrenau,R., Pennathur,A., Ogino,S.,
Luketich,J.D., Golub,T.R., Gabriel,S.B., Lander,E.S., Beer,D.G.,
Godfrey,T.E., Getz,G. and Bass,A.J.
TITLE Exome and whole-genome sequencing of esophageal adenocarcinoma
identifies recurrent driver events and mutational complexity
JOURNAL Nat. Genet. 45 (5), 478-486 (2013)
PUBMED 23525077
REMARK GeneRIF: DOCK2 mutations are associated with esophageal
adenocarcinoma.
REFERENCE 2 (bases 1 to 6117)
AUTHORS Lauc,G., Huffman,J.E., Pucic,M., Zgaga,L., Adamczyk,B., Muzinic,A.,
Novokmet,M., Polasek,O., Gornik,O., Kristic,J., Keser,T.,
Vitart,V., Scheijen,B., Uh,H.W., Molokhia,M., Patrick,A.L.,
McKeigue,P., Kolcic,I., Lukic,I.K., Swann,O., van Leeuwen,F.N.,
Ruhaak,L.R., Houwing-Duistermaat,J.J., Slagboom,P.E., Beekman,M.,
de Craen,A.J., Deelder,A.M., Zeng,Q., Wang,W., Hastie,N.D.,
Gyllensten,U., Wilson,J.F., Wuhrer,M., Wright,A.F., Rudd,P.M.,
Hayward,C., Aulchenko,Y., Campbell,H. and Rudan,I.
TITLE Loci associated with N-glycosylation of human immunoglobulin G show
pleiotropy with autoimmune diseases and haematological cancers
JOURNAL PLoS Genet. 9 (1), E1003225 (2013)
PUBMED 23382691
REFERENCE 3 (bases 1 to 6117)
AUTHORS Hanawa-Suetsugu,K., Kukimoto-Niino,M., Mishima-Tsumagari,C.,
Akasaka,R., Ohsawa,N., Sekine,S., Ito,T., Tochio,N., Koshiba,S.,
Kigawa,T., Terada,T., Shirouzu,M., Nishikimi,A., Uruno,T.,
Katakai,T., Kinashi,T., Kohda,D., Fukui,Y. and Yokoyama,S.
TITLE Structural basis for mutual relief of the Rac guanine nucleotide
exchange factor DOCK2 and its partner ELMO1 from their
autoinhibited forms
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 109 (9), 3305-3310 (2012)
PUBMED 22331897
REMARK GeneRIF: The C-terminal Pro-rich tail of ELMO1 winds around the
Src-homology 3 domain of DOCK2 to form an intermolecular 5-helix
bundle. The entire regions of both DOCK2 a& ELMO1 assemble to
create a rigid structure required for the DOCK2 & ELMO1 binding.
REFERENCE 4 (bases 1 to 6117)
AUTHORS El-Haibi,C.P., Singh,R., Sharma,P.K., Singh,S. and Lillard,J.W. Jr.
TITLE CXCL13 mediates prostate cancer cell proliferation through JNK
signalling and invasion through ERK activation
JOURNAL Cell Prolif. 44 (4), 311-319 (2011)
PUBMED 21645150
REMARK GeneRIF: Our results show CXCL13-mediated PCa cell invasion
requires Akt and ERK12 activation and suggests a new role for DOCK2
in proliferation of hormone-refractory CXCR5-positive PCa cells.
REFERENCE 5 (bases 1 to 6117)
AUTHORS Bailey,S.D., Xie,C., Do,R., Montpetit,A., Diaz,R., Mohan,V.,
Keavney,B., Yusuf,S., Gerstein,H.C., Engert,J.C. and Anand,S.
CONSRTM DREAM investigators
TITLE Variation at the NFATC2 locus increases the risk of
thiazolidinedione-induced edema in the Diabetes REduction
Assessment with ramipril and rosiglitazone Medication (DREAM) study
JOURNAL Diabetes Care 33 (10), 2250-2253 (2010)
PUBMED 20628086
REMARK GeneRIF: Observational study of gene-disease association,
gene-environment interaction, and pharmacogenomic / toxicogenomic.
(HuGE Navigator)
REFERENCE 6 (bases 1 to 6117)
AUTHORS Nishihara,H., Maeda,M., Tsuda,M., Makino,Y., Sawa,H., Nagashima,K.
and Tanaka,S.
TITLE DOCK2 mediates T cell receptor-induced activation of Rac2 and IL-2
transcription
JOURNAL Biochem. Biophys. Res. Commun. 296 (3), 716-720 (2002)
PUBMED 12176041
REMARK GeneRIF: DOCK2 mediates T cell receptor-induced activation of Rac2
and IL-2 transcription in jurkat cells
REFERENCE 7 (bases 1 to 6117)
AUTHORS Reif,K. and Cyster,J.
TITLE The CDM protein DOCK2 in lymphocyte migration
JOURNAL Trends Cell Biol. 12 (8), 368-373 (2002)
PUBMED 12191913
REMARK Review article
REFERENCE 8 (bases 1 to 6117)
AUTHORS Brugnera,E., Haney,L., Grimsley,C., Lu,M., Walk,S.F.,
Tosello-Trampont,A.C., Macara,I.G., Madhani,H., Fink,G.R. and
Ravichandran,K.S.
TITLE Unconventional Rac-GEF activity is mediated through the
Dock180-ELMO complex
JOURNAL Nat. Cell Biol. 4 (8), 574-582 (2002)
PUBMED 12134158
REFERENCE 9 (bases 1 to 6117)
AUTHORS Fukui,Y., Hashimoto,O., Sanui,T., Oono,T., Koga,H., Abe,M.,
Inayoshi,A., Noda,M., Oike,M., Shirai,T. and Sasazuki,T.
TITLE Haematopoietic cell-specific CDM family protein DOCK2 is essential
for lymphocyte migration
JOURNAL Nature 412 (6849), 826-831 (2001)
PUBMED 11518968
REFERENCE 10 (bases 1 to 6117)
AUTHORS Nishihara,H., Kobayashi,S., Hashimoto,Y., Ohba,F., Mochizuki,N.,
Kurata,T., Nagashima,K. and Matsuda,M.
TITLE Non-adherent cell-specific expression of DOCK2, a member of the
human CDM-family proteins
JOURNAL Biochim. Biophys. Acta 1452 (2), 179-187 (1999)
PUBMED 10559471
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DB145764.1, BC104900.1, BC035613.1, BF110460.1 and BC084556.1.
On Sep 19, 2008 this sequence version replaced gi:31377467.
Summary: The protein encoded by this gene belongs to the CDM
protein family. It is specifically expressed in hematopoietic
cells, predominantly in the peripheral blood leukocytes, and is
involved in remodeling of the actin cytoskeleton required for
lymphocyte migration, through the activation of RAC. Mice lacking
this gene show a severe impairment in the migration and homing of
lymphocytes. These mutant mice also exhibited long-term survival of
allografts, suggesting that this gene may be a target for
controlling transplant rejection. [provided by RefSeq, Oct 2011].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: D86964.1, BC104900.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025088 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-44 DB145764.1 1-44
45-3274 BC104900.1 1-3230
3275-3535 BC035613.1 916-1176
3536-5649 BC104900.1 3492-5605
5650-5854 BF110460.1 251-455
5855-6117 BC084556.1 2136-2398
FEATURES Location/Qualifiers
source 1..6117
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q35.1"
gene 1..6117
/gene="DOCK2"
/note="dedicator of cytokinesis 2"
/db_xref="GeneID:1794"
/db_xref="HGNC:2988"
/db_xref="HPRD:09121"
/db_xref="MIM:603122"
exon 1..123
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
misc_feature 39..41
/gene="DOCK2"
/note="upstream in-frame stop codon"
CDS 81..5573
/gene="DOCK2"
/note="dedicator of cyto-kinesis 2"
/codon_start=1
/product="dedicator of cytokinesis protein 2"
/protein_id="NP_004937.1"
/db_xref="GI:31377468"
/db_xref="CCDS:CCDS4371.1"
/db_xref="GeneID:1794"
/db_xref="HGNC:2988"
/db_xref="HPRD:09121"
/db_xref="MIM:603122"
/translation="
MAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFPKSFIHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSMMYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSVISLFHAHEEATDKITERIKEEMSKDQPDYAMYSRISSSPTHSLYVFVRNFVCRIGEDAELFMSLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDFLHSLLGKVIASKGDSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNLMKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQDAAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHFVACMTAILNQMGDQHYSFYIETFQTSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTNFEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRSMLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSRKHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKSAEEGKQIPDSLSTDL
"
misc_feature 114..281
/gene="DOCK2"
/note="Src Homology 3 domain of Class A Dedicator of
Cytokinesis protein 2; Region: SH3_DOCK2_A; cd12050"
/db_xref="CDD:212983"
misc_feature order(120..134,153..155,168..176,180..182,192..197,
207..212,216..218,240..242,246..248,252..254,258..260,
264..269,273..275,279..281)
/gene="DOCK2"
/note="ELMO interaction site [polypeptide binding]; other
site"
/db_xref="CDD:212983"
misc_feature order(129..131,135..137,144..146,156..158,207..212,
258..260,264..269)
/gene="DOCK2"
/note="peptide ligand binding site [polypeptide binding];
other site"
/db_xref="CDD:212983"
misc_feature 705..707
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 714..716
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 990..992
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q92608.2); acetylation site"
misc_feature 1344..1931
/gene="DOCK2"
/note="C2 domain; Region: C2; cl14603"
/db_xref="CDD:212363"
misc_feature 1842..1844
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q92608.2); phosphorylation site"
misc_feature 1857..1859
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q92608.2); phosphorylation site"
misc_feature 2292..2294
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q92608.2); acetylation site"
misc_feature 2895..4508
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q92608.2);
Region: Interaction with CRKL"
misc_feature 3678..4940
/gene="DOCK2"
/note="Dock Homology Region 2, a GEF domain, of Class A
Dedicator of Cytokinesis 2; Region: DHR2_DOCK2; cd11706"
/db_xref="CDD:212579"
misc_feature order(3984..3986,4005..4013,4017..4019,4023..4028,
4032..4037,4044..4049,4053..4058,4065..4070,4077..4079,
4338..4340,4350..4361,4368..4370)
/gene="DOCK2"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:212579"
misc_feature order(4182..4184,4188..4199,4245..4253,4302..4310,
4410..4421,4452..4457,4464..4466,4581..4583,4593..4595,
4653..4658,4662..4667,4677..4682,4689..4709,4716..4718,
4806..4808,4854..4856,4860..4865,4872..4874,4881..4883)
/gene="DOCK2"
/note="Rac binding site [polypeptide binding]; other site"
/db_xref="CDD:212579"
misc_feature 4689..4706
/gene="DOCK2"
/note="nucleotide sensor; other site"
/db_xref="CDD:212579"
misc_feature 5133..5135
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q92608.2); phosphorylation site"
misc_feature 5142..5144
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 5145..5147
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 5196..5198
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 5271..5273
/gene="DOCK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q92608.2); phosphorylation site"
variation 112
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200033547"
exon 124..207
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 131
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:185449432"
variation 147
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376950305"
variation 170
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:141894939"
variation 173
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370494583"
variation 179
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374789654"
exon 208..248
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 214
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150182906"
variation 228
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200852440"
exon 249..304
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 301
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368156237"
exon 305..401
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 311
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377614169"
variation 318
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201979117"
variation 320
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:185282572"
variation 344
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201493926"
variation 358
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138714263"
variation 359
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:144632263"
variation 366
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370949354"
exon 402..550
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 431
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112922689"
variation 446
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:35393134"
variation 469
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:78450053"
variation 479
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140206456"
variation 485
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373741346"
variation 542
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:367573686"
variation 550
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371312059"
exon 551..686
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 587
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202075394"
variation 599
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146530031"
variation 600
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200805864"
variation 617
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:143962640"
variation 660
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147299638"
exon 687..841
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 705
/gene="DOCK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:148418103"
variation 711
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:151191554"
variation 720
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150969388"
variation 737
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:34039776"
variation 747
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:370094182"
variation 815
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374307327"
variation 816
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139449745"
variation 832
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:78243868"
variation 833
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146746458"
variation 834
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140430355"
exon 842..923
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 848
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:145405039"
variation 890
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189140579"
variation 908
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368563028"
variation 914
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:370245029"
exon 924..1059
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 927
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369315365"
variation 986
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146489287"
variation 1028
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199921409"
exon 1060..1135
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1072
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:149096712"
variation 1097
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:375687811"
variation 1103
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:368378335"
variation 1114
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112557122"
exon 1136..1212
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1142
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143288655"
exon 1213..1338
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1226
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200816827"
variation 1292
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:2112703"
variation 1295
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141406325"
exon 1339..1463
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1368
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:370264550"
variation 1373
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377517116"
variation 1396
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:113673055"
variation 1414
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371303142"
variation 1440
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114888195"
variation 1441
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374175915"
variation 1446
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368892236"
variation 1454
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2306559"
variation 1457
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144520292"
exon 1464..1562
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1470
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372498181"
variation 1476
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200560235"
variation 1497
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201626676"
variation 1515
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370114623"
variation 1517
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:147336443"
variation 1529
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139876228"
variation 1562
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:192453842"
exon 1563..1635
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1566
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371391395"
variation 1589
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:369688871"
variation 1626
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201439364"
exon 1636..1739
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1674
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149411090"
variation 1677
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375363462"
variation 1680
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373197319"
variation 1683
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143942535"
variation 1709
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148641505"
variation 1722
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143137802"
exon 1740..1923
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1746
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199853621"
variation 1748
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139368328"
variation 1770
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144145929"
variation 1818
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:151022836"
variation 1822
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140817788"
variation 1823
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201495849"
variation 1840
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201774749"
variation 1847
/gene="DOCK2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:34864600"
variation 1881
/gene="DOCK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:111348804"
exon 1924..2021
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 1953
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149106608"
variation 2004
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:184460829"
exon 2022..2111
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2063
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371790704"
variation 2066
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368933125"
exon 2112..2212
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2130
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:35832136"
variation 2162
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145746510"
variation 2186
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:75416239"
exon 2213..2347
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2215
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368031697"
variation 2279
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:35530753"
variation 2321
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:35887608"
variation 2322
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199603412"
variation 2329
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373947127"
variation 2330
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200305228"
variation 2334
/gene="DOCK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:371936048"
exon 2348..2456
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2354
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138285820"
variation 2358
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371785252"
variation 2378
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372634514"
variation 2432
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:13155521"
variation 2433
/gene="DOCK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:376374557"
exon 2457..2527
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2472
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373025633"
exon 2528..2634
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2539
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370192291"
variation 2540
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146897720"
variation 2600
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374883782"
variation 2604
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372598080"
variation 2605
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148384873"
exon 2635..2783
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2658
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201511979"
variation 2661
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369306554"
variation 2667
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:141501849"
variation 2715
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150884555"
variation 2718
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:112062072"
variation 2735
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141649591"
variation 2736
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199862297"
exon 2784..2879
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2807
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:261623"
variation 2837
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376912207"
variation 2842
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370529585"
variation 2862
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200070944"
exon 2880..2978
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 2937
/gene="DOCK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:144126398"
variation 2938
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:35395501"
variation 2947
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:188136128"
exon 2979..3073
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3019
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148694888"
variation 3026
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:36028557"
exon 3074..3152
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3080
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:151197976"
variation 3098
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374774675"
variation 3133
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201825096"
variation 3136
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368028175"
variation 3137
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:150071550"
exon 3153..3253
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3220
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:145444170"
variation 3227
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199995403"
exon 3254..3312
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3271
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:185160653"
variation 3272
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:58980222"
variation 3273
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368843643"
variation 3275
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:2287727"
exon 3313..3461
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3339
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:187197739"
variation 3351
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150196463"
variation 3365
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138927937"
variation 3391
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149008494"
variation 3446
/gene="DOCK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:200973349"
exon 3462..3547
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3482
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143743514"
variation 3494
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148138145"
variation 3497
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149853735"
variation 3515
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370111673"
variation 3518
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181479183"
variation 3536
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:9791113"
exon 3548..3704
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3584
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200201722"
variation 3589
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:137955744"
variation 3617..3618
/gene="DOCK2"
/replace=""
/replace="a"
/db_xref="dbSNP:34576936"
variation 3679
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373428643"
variation 3692
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3763048"
exon 3705..3745
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
exon 3746..3836
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3763
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139600790"
variation 3764
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149321142"
variation 3777
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:193074993"
variation 3821
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144649763"
variation 3825
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139639543"
variation 3828
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:184632847"
exon 3837..3956
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3891
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200108047"
variation 3900
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377233075"
variation 3901
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145262338"
variation 3908
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:6555882"
variation 3916
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145873210"
variation 3917
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:142249400"
variation 3923
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:151251345"
variation 3934
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369071999"
exon 3957..4046
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 3968
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140468355"
variation 3994
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370316549"
variation 3995
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150482679"
variation 4005
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146643993"
variation 4025
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:34133853"
variation 4031
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:145117786"
exon 4047..4151
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4084
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:60146068"
variation 4124
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199913251"
exon 4152..4293
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4158
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:137922056"
variation 4172
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142465529"
variation 4231
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375716929"
variation 4263
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201799740"
variation 4281
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:143100569"
exon 4294..4375
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4364
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:76688275"
exon 4376..4460
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4388
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141164963"
variation 4394
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:17647491"
variation 4421
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181184602"
variation 4422
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200408270"
variation 4432
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199755413"
variation 4436
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139781718"
exon 4461..4547
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4488
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143595882"
variation 4508
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147192858"
variation 4518
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374174531"
variation 4535
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140777013"
variation 4543
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149796867"
exon 4548..4724
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4554
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371649588"
variation 4591
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201320169"
variation 4592
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376411478"
variation 4603
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145786592"
variation 4613
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:148502872"
variation 4676
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372927020"
variation 4715
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377205336"
exon 4725..4808
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4753
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:13179480"
variation 4755
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:199737175"
variation 4770
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199902117"
variation 4781
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:376091703"
variation 4783
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:13179490"
exon 4809..4946
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4874
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369880478"
variation 4901
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:377080151"
variation 4904
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375128647"
variation 4931
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375712443"
variation 4934
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2270900"
variation 4938
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:142830212"
exon 4947..5074
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 4958
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201318538"
variation 4959
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368481515"
variation 4976
/gene="DOCK2"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1045168"
variation 5035
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:113216049"
variation 5039
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145086586"
variation 5056
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:139644615"
exon 5075..5246
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 5082
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:377100198"
variation 5104
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201322810"
variation 5107
/gene="DOCK2"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:150108225"
variation 5119
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373168304"
variation 5128
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:184196863"
variation 5129
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201405765"
variation 5137
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377714619"
variation 5138
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138544957"
variation 5150
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149235480"
variation 5154
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373978300"
variation 5159
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:146935890"
variation 5167
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371229305"
variation 5169
/gene="DOCK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201624889"
variation 5171
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:138159817"
variation 5209
/gene="DOCK2"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:200684209"
variation 5210
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143741887"
variation 5234
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147230385"
variation 5245
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199698060"
exon 5247..5367
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 5267
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:147774003"
variation 5297
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148811648"
variation 5306
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202096890"
variation 5315
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201601393"
variation 5318
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:113012149"
variation 5339
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138826774"
variation 5348
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370450130"
exon 5368..5510
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 5374
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141274816"
variation 5375
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370911923"
variation 5404
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:58570833"
variation 5415
/gene="DOCK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:2270898"
variation 5424
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149343589"
variation 5425
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376280359"
variation 5441
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149976182"
variation 5457
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146061014"
variation 5470
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140044343"
variation 5478
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368448938"
variation 5482
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143896166"
variation 5505
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146886839"
exon 5511..6097
/gene="DOCK2"
/inference="alignment:Splign:1.39.8"
variation 5519
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:371835495"
STS 5521..5709
/gene="DOCK2"
/standard_name="RH25421"
/db_xref="UniSTS:5858"
variation 5525
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200128185"
variation 5526
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:144315682"
variation 5555
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114098294"
variation 5558
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:151161252"
variation 5563
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202005409"
variation 5564
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140198889"
variation 5597
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369628471"
variation 5640
/gene="DOCK2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:55803405"
variation 5665
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:183929574"
variation 5672
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:187711257"
variation 5731
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:1045176"
variation 5734
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:9307"
variation 5761
/gene="DOCK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:147788572"
variation 5792
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192346052"
variation 5892
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114945769"
variation 5901
/gene="DOCK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1045192"
STS 5997..6096
/gene="DOCK2"
/standard_name="SGC32167"
/db_xref="UniSTS:82994"
variation 6009
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376770574"
variation 6017
/gene="DOCK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:57495438"
variation 6047
/gene="DOCK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:184485182"
ORIGIN
aggaaggaagtggggccctgcggcgcccagccaccccctgacggcttccccacgggaggacgcgaggccccggcccagccatggccccctggcgcaaagctgacaaggagcggcacggcgtggccatatacaacttccaaggcagcggagccccccagctctccctgcagatcggcgatgtggtgcgaatacaggagacgtgtggagactggtataggggatacctcataaagcacaaaatgttacagggcatttttcctaagtcatttatccacatcaaggaagtgacagttgagaaaagaagaaatactgagaacatcattcctgcagaaattcctctggcacaagaagtgacaacgacactttgggaatggggaagcatctggaaacaactctatgtggccagcaaaaaggagcgttttctccaggtgcagtccatgatgtacgatctgatggagtggaggtcccagcttctctcaggaaccttacccaaggatgagctgaaggaactgaagcagaaagtcacgtccaaaattgactatggcaacaaaatccttgagcttgatttgattgtcagagatgaagacggaaatatcttggaccctgataataccagtgtcatcagcttgttccatgcacatgaggaagcaactgataaaatcacagagcgtatcaaagaagaaatgtcaaaagaccagccagattatgcaatgtattcccggatctcctcatcccccacccatagcctctatgtgtttgtgagaaactttgtgtgcagaattggggaagatgctgagctcttcatgtctctctacgaccccaacaagcaaacggtcataagtgagaactacctagtgcgatggggcagccggggcttccctaaggagattgagatgctcaacaatctgaaggtggtcttcacggatcttggaaacaaagacctcaacagggataaaatttacttgatttgtcaaatagtccgggtcggcaagatggatcttaaggatactggtgcaaagaagtgcacgcagggactgaggaggccctttggggtggcagttatggatataacagacatcatcaaggggaaagcagagagtgatgaagaaaagcagcacttcattccttttcacccggttacagctgagaatgacttcctacacagcctgctgggcaaagtcatagcctccaagggggacagtggagggcaaggcctctgggtgaccatgaagatgctggtgggtgacatcattcagattcgcaaggactatccacacctggtggacaggaccaccgtggtggccaggaagctgggattcccagagatcatcatgccaggggatgtcaggaacgacatctacattactctcttacaaggtgactttgacaagtacaacaagaccacacagaggaatgtggaagtcatcatgtgtgtgtgcgcggaggatggcaaaacgctgcctaatgcaatttgcgtgggagcaggggacaagcccatgaatgagtatcgctccgttgtgtactatcaagtcaaacagccacgctggatggaaacagtcaaggtggctgtccctattgaagacatgcagaggatccatctgcgattcatgtttcgacatcggtcatctctggaatctaaagataaaggagaaaagaactttgccatgtcctatgtgaagctgatgaaagaagatgggactactctacacgatggattccatgacttagttgtcctcaagggggacagcaagaagatggaggatgccagcgcatacctgacccttccttcttatcgacaccatgtggaaaacaagggggccacgctgagcaggagctccagcagtgttggggggctttctgtcagctcccgggatgtgttctccatttccaccctggtgtgctccacaaagctcactcagaatgtgggcttgctgggtttgctgaagtggcgtatgaagcctcaactgctacaggagaatttagaaaagttgaagattgtggatggagaggaagtggtgaagtttctccaggatactctggatgccctcttcaacatcatgatggagcattctcaaagtgatgaatatgacatcctcgtctttgatgccttgatttacataataggactcattgcagaccggaaatttcagcatttcaacaccgttctggaggcttacatccaacagcatttcagtgcgaccttggcttacaagaaattgatgacagtgctgaagacttacttggatacctccagcagaggggagcaatgtgagccaatcctaagaacgctgaaggctttggaatatgtgttcaagttcattgttcggtcgaggacattattttcacagctttatgaaggcaaagaacagatggagtttgaagaatccatgagacggctctttgaatccatcaacaatctgatgaaaagtcaatacaaaactaccatccttttgcaggtggcggctttgaaatacatcccatctgtcctgcatgatgtagaaatggtctttgatgcgaagttactcagccaactcctgtatgagttctacacctgcatccctcctgtgaaactccagaagcagaaagtacagtctatgaatgagatagtccagagcaacctctttaaaaagcaagaatgccgggacattctgcttcctgtcatcaccaaagagctgaaggagctgctggagcagaaggatgacatgcaacaccaggtcctggagaggaagtactgcgttgaattgctcaacagcatcttggaagtccttagctaccaggatgcggccttcacctaccaccatatccaggagatcatggtccagctgctgcggacagtgaaccggacagtcatcaccatgggccgggatcacattctgattagtcactttgtggcatgtatgacagccatcttaaaccagatgggtgaccagcactactccttctacattgagaccttccagaccagctctgaacttgtggacttcttgatggagaccttcatcatgttcaaggacctcattggaaagaacgtgtaccctggagactggatggccatgagcatggttcaaaacagggtcttcctgagagctatcaacaagtttgcagaaaccatgaaccagaagttcctagaacacacgaactttgagttccagctgtggaacaactattttcatctggcagtggcttttatcacccaggattctctgcagctggagcagttctcacacgccaaatacaacaaaatcctgaataagtatggggacatgagacggctaattggcttctccatccgtgatatgtggtacaagcttggtcagaacaaaatctgcttcatcccaggcatggtaggacctatattagagatgacacttatccctgaggctgagctccggaaagccaccataccaatcttcttcgacatgatgctgtgtgaatatcaaagaagtggggatttcaaaaagtttgaaaacgaaatcatcctgaagctggaccacgaggtagaagggggccgaggcgacgagcagtacatgcagctcctggagtcaatcctgatggaatgtgctgcagagcacccaaccattgccaagtcggtggagaacttcgtgaacctggtcaaaggcctcctggagaagctgctggattaccggggtgtgatgacagatgagagcaaagacaaccgcatgagctgcaccgtgaacctgctgaatttctacaaagataacaacagggaggagatgtacataaggtacctgtacaaactccgcgatcttcacctggactgtgacaattacacagaggctgcctacacgctccttctccacacctggcttctcaagtggtcggatgagcagtgtgcatcacaggtcatgcagacaggccagcagcacccccagacacaccggcagctgaaggagacgctctacgagaccatcataggctactttgacaaaggaaagatgtgggaagaggccataagtctgtgcaaggagctggcggaacagtacgagatggagatctttgactatgagctgctcagccagaacctgatccagcaggcaaaattctatgaaagcatcatgaaaatcctcaggcccaaaccagactactttgctgttggatactacggccagggattcccctccttcctgcggaacaaagtgttcatctaccgcgggaaggaatatgagcgaagagaagatttccagatgcagctgatgacccagttccccaatgcagagaagatgaacaccacctctgccccgggagatgatgtgaagaatgccccaggccagtatatccagtgcttcactgtccagcctgtcttggatgaacatcccaggttcaagaataagccagtgcctgaccagattataaacttctacaaatccaactacgtgcaaaggttccactactcccggcccgtgcgcagggggaccgtagacccagagaatgagtttgcttccatgtggattgagagaacctccttcgtgactgcatacaagctgccggggatcctgcgctggtttgaggtggtgcacatgtcgcagaccacaattagtcctctggagaatgccatagaaaccatgtccacggccaatgagaagatcctgatgatgataaaccagtaccagagtgatgagaccctccccatcaacccactctccatgctcctgaacgggattgtggaccctgctgtcatgggaggcttcgccaagtatgagaaggccttcttcactgaagagtatgtcagggaccaccctgaggaccaggacaagctgacccacctcaaggacctgattgcatggcagatccccttcttgggagctgggattaagatccatgagaaaagggtgtcagataacttgcgacccttccatgaccggatggaggaatgtttcaagaacctgaaaatgaaggtggagaaggagtacggtgtccgagagatgcctgactttgacgacaggagagtgggccgtcccaggtctatgctgcgctcatacagacagatgtccatcatctctctggcttccatgaattctgactgcagcacccccagcaagcctacctcagagagctttgacctggaattagcatcacccaagacgccgagagtggagcaggaggaaccgatctccccggggagcaccctgcctgaggtcaagctgcggaggtccaagaagaggacaaagagaagcagcgtagtttttgcggatgagaaagcagctgcagagtcggacctgaagcggctttccaggaagcatgagttcatgagtgacaccaacctctcggagcatgcggccatccccctcaaggcgtctgtcctctctcaaatgagctttgccagccagtccatgcctaccatcccagccctggcgctctcagtggcaggcatccctgggttggatgaggccaacacatctccccgcctcagccagaccttcctccaactctcagatggtgacaagaagacactcacacggaagaaggtcaatcagttcttcaagacaatgctggccagcaaatcggctgaagaaggcaaacagatcccagactcgctgtccacggacctgtgagctgctgctgactagggctgcatgggagagccagggaggggagtttctggaagaggaaagccatgcgtggaacatcgaagcctcagagagtgggagactgtccccatcagttgtccttacttagaggagacagagaggccaatcaggtcccagagcttgaatgctaacaagcccagcatcccctggggctgtgatcatggtggatgaggaagcctcaacgtagattcctgaactcaaggtaccagcaagaatgccttctcccagtgtgctctccccaacatcctaggcacagctttcataacccagtttcttaggtgtaagaaactgtttttatctcatttattaagtctcagaacttaacagaaaaggaagccttttaaatattctttttaattttattttagattaacagttttgtactttacatttttttatacaaccaaccagtttcttttctagccaatcatctctgaagagttgctgtttcttactgacaataaaaaatgttctcttggttcgaataaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:1794 -> Molecular function: GO:0009055 [electron carrier activity] evidence: IEA
GeneID:1794 -> Molecular function: GO:0020037 [heme binding] evidence: IEA
GeneID:1794 -> Molecular function: GO:0030675 [Rac GTPase activator activity] evidence: IEA
GeneID:1794 -> Molecular function: GO:0030676 [Rac guanyl-nucleotide exchange factor activity] evidence: IDA
GeneID:1794 -> Molecular function: GO:0042608 [T cell receptor binding] evidence: IDA
GeneID:1794 -> Biological process: GO:0001766 [membrane raft polarization] evidence: IEA
GeneID:1794 -> Biological process: GO:0001768 [establishment of T cell polarity] evidence: IEA
GeneID:1794 -> Biological process: GO:0001771 [immunological synapse formation] evidence: IEA
GeneID:1794 -> Biological process: GO:0002277 [myeloid dendritic cell activation involved in immune response] evidence: ISS
GeneID:1794 -> Biological process: GO:0006935 [chemotaxis] evidence: IEA
GeneID:1794 -> Biological process: GO:0007264 [small GTPase mediated signal transduction] evidence: IEA
GeneID:1794 -> Biological process: GO:0016032 [viral process] evidence: TAS
GeneID:1794 -> Biological process: GO:0030036 [actin cytoskeleton organization] evidence: TAS
GeneID:1794 -> Biological process: GO:0044351 [macropinocytosis] evidence: ISS
GeneID:1794 -> Biological process: GO:0045059 [positive thymic T cell selection] evidence: IEA
GeneID:1794 -> Biological process: GO:0045060 [negative thymic T cell selection] evidence: IEA
GeneID:1794 -> Biological process: GO:0046633 [alpha-beta T cell proliferation] evidence: IEA
GeneID:1794 -> Biological process: GO:0050690 [regulation of defense response to virus by virus] evidence: TAS
GeneID:1794 -> Biological process: GO:0050766 [positive regulation of phagocytosis] evidence: ISS
GeneID:1794 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:1794 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA
GeneID:1794 -> Cellular component: GO:0012505 [endomembrane system] evidence: IEA
GeneID:1794 -> Cellular component: GO:0016020 [membrane] evidence: IEA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.