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2025-05-09 16:37:24, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_003940 7933 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens ubiquitin specific peptidase 13 (isopeptidase T-3)
(USP13), mRNA.
ACCESSION NM_003940
VERSION NM_003940.2 GI:215598687
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7933)
AUTHORS Liu,J., Xia,H., Kim,M., Xu,L., Li,Y., Zhang,L., Cai,Y.,
Norberg,H.V., Zhang,T., Furuya,T., Jin,M., Zhu,Z., Wang,H., Yu,J.,
Li,Y., Hao,Y., Choi,A., Ke,H., Ma,D. and Yuan,J.
TITLE Beclin1 controls the levels of p53 by regulating the
deubiquitination activity of USP10 and USP13
JOURNAL Cell 147 (1), 223-234 (2011)
PUBMED 21962518
REMARK GeneRIF: USP10 mediates the deubiquitination of p53, regulating
deubiquitination activity of USP10 and USP13 by Beclin1 provides a
mechanism for Beclin1 to control the levels of p53.
REFERENCE 2 (bases 1 to 7933)
AUTHORS Scortegagna,M., Subtil,T., Qi,J., Kim,H., Zhao,W., Gu,W., Kluger,H.
and Ronai,Z.A.
TITLE USP13 enzyme regulates Siah2 ligase stability and activity via
noncatalytic ubiquitin-binding domains
JOURNAL J. Biol. Chem. 286 (31), 27333-27341 (2011)
PUBMED 21659512
REMARK GeneRIF: study identifies a new layer of Siah2 regulation mediated
by USP13 binding to ubiquitinated Siah2 protein with a concomitant
inhibitory effect on its activity under normoxia
REFERENCE 3 (bases 1 to 7933)
AUTHORS Zhao,X., Fiske,B., Kawakami,A., Li,J. and Fisher,D.E.
TITLE Regulation of MITF stability by the USP13 deubiquitinase
JOURNAL Nat Commun 2, 414 (2011)
PUBMED 21811243
REMARK GeneRIF: Through deubiquitination, USP13 stabilizes and upregulates
MITF protein levels.
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 7933)
AUTHORS Sowa,M.E., Bennett,E.J., Gygi,S.P. and Harper,J.W.
TITLE Defining the human deubiquitinating enzyme interaction landscape
JOURNAL Cell 138 (2), 389-403 (2009)
PUBMED 19615732
REFERENCE 5 (bases 1 to 7933)
AUTHORS McElhinny,A.S., Kakinuma,K., Sorimachi,H., Labeit,S. and
Gregorio,C.C.
TITLE Muscle-specific RING finger-1 interacts with titin to regulate
sarcomeric M-line and thick filament structure and may have nuclear
functions via its interaction with glucocorticoid modulatory
element binding protein-1
JOURNAL J. Cell Biol. 157 (1), 125-136 (2002)
PUBMED 11927605
REFERENCE 6 (bases 1 to 7933)
AUTHORS Timms,K.M., Ansari-Lari,M.A., Morris,W., Brown,S.N. and Gibbs,R.A.
TITLE The genomic organization of Isopeptidase T-3 (ISOT-3), a new member
of the ubiquitin specific protease family (UBP)
JOURNAL Gene 217 (1-2), 101-106 (1998)
PUBMED 9841226
REFERENCE 7 (bases 1 to 7933)
AUTHORS D'Andrea,A. and Pellman,D.
TITLE Deubiquitinating enzymes: a new class of biological regulators
JOURNAL Crit. Rev. Biochem. Mol. Biol. 33 (5), 337-352 (1998)
PUBMED 9827704
REMARK Review article
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AC125604.5, BC016146.1 and AC007687.17.
On Dec 4, 2008 this sequence version replaced gi:4507848.
##Evidence-Data-START##
Transcript exon combination :: U75362.1, BC016146.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025083, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-47 AC125604.5 11738-11784
48-2736 BC016146.1 1-2689
2737-7933 AC007687.17 74479-79675 c
FEATURES Location/Qualifiers
source 1..7933
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3q26.2-q26.3"
gene 1..7933
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="ubiquitin specific peptidase 13 (isopeptidase T-3)"
/db_xref="GeneID:8975"
/db_xref="HGNC:12611"
/db_xref="MIM:603591"
exon 1..249
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 63
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370443197"
variation 76
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:200016596"
CDS 82..2673
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/EC_number="3.4.19.12"
/note="ubiquitin specific protease 13 (isopeptidase T-3);
ubiquitin thiolesterase 13; ubiquitin thioesterase 13;
deubiquitinating enzyme 13; ubiquitin-specific-processing
protease 13"
/codon_start=1
/product="ubiquitin carboxyl-terminal hydrolase 13"
/protein_id="NP_003931.2"
/db_xref="GI:215598688"
/db_xref="CCDS:CCDS3235.1"
/db_xref="GeneID:8975"
/db_xref="HGNC:12611"
/db_xref="MIM:603591"
/translation="
MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEGGLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDLDTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPDTWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEMENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKVCASERPPKDLGYMYFYRRIPS
"
misc_feature 169..2664
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="Isopeptidase T [Posttranslational modification,
protein turnover, chaperones]; Region: UBP14; COG5207"
/db_xref="CDD:34804"
misc_feature 421..423
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q92995.2); phosphorylation site"
misc_feature 445..447
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q92995.2); phosphorylation site"
misc_feature 712..933
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="Zn-finger in ubiquitin-hydrolases and other
protein; Region: zf-UBP; pfam02148"
/db_xref="CDD:202130"
misc_feature 1090..>1911
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="A subfamily of Peptidase C19. Peptidase C19
contains ubiquitinyl hydrolases. They are intracellular
peptidases that remove ubiquitin molecules from
polyubiquinated peptides by cleavage of isopeptide bonds.
They hydrolyze bonds involving the carboxyl...; Region:
Peptidase_C19B; cd02658"
/db_xref="CDD:73064"
misc_feature order(1099..1101,1114..1116)
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="active site"
/db_xref="CDD:73064"
misc_feature 2041..2154
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="Ubiquitin Associated domain. The UBA domain is a
commonly occurring sequence motif in some members of the
ubiquitination pathway, UV excision repair proteins, and
certain protein kinases. Although its specific role is so
far unknown, it has been...; Region: UBA; cd00194"
/db_xref="CDD:29156"
misc_feature order(2071..2079,2152..2154)
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="putative protein-protein interaction site; other
site"
/db_xref="CDD:29156"
misc_feature 2074..2082
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="GFP-loop; other site"
/db_xref="CDD:29156"
misc_feature 2269..2379
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="Ubiquitin Associated domain. The UBA domain is a
commonly occurring sequence motif in some members of the
ubiquitination pathway, UV excision repair proteins, and
certain protein kinases. Although its specific role is so
far unknown, it has been...; Region: UBA; cd00194"
/db_xref="CDD:29156"
misc_feature order(2296..2304,2374..2376)
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="putative protein-protein interaction site; other
site"
/db_xref="CDD:29156"
misc_feature 2299..2307
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="GFP-loop; other site"
/db_xref="CDD:29156"
misc_feature <2485..2658
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="Peptidase C19 contains ubiquitinyl hydrolases. They
are intracellular peptidases that remove ubiquitin
molecules from polyubiquinated peptides by cleavage of
isopeptide bonds. They hydrolyse bonds involving the
carboxyl group of the C-terminal Gly...; Region:
Peptidase_C19; cl02553"
/db_xref="CDD:194354"
misc_feature order(2548..2550,2596..2598)
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/note="active site"
/db_xref="CDD:73062"
variation 92
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:374896625"
variation 97
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:368406240"
variation 117
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:193177026"
variation 142
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373833022"
variation 156
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144481641"
variation 176
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:147844491"
variation 210
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:372813389"
variation 222
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:2276803"
variation 245
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:376341612"
exon 250..375
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 267
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:369204855"
variation 370
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:372042233"
exon 376..436
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 390
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:372822087"
variation 401
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:61760203"
variation 426
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:145034700"
variation 433
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:77083687"
exon 437..558
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 439
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:375786336"
variation 452
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:149046448"
variation 464
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:144680708"
variation 492
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370081055"
exon 559..701
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 583
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:367898662"
variation 625
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:141550831"
variation 660
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:145278369"
variation 699
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:16830742"
exon 702..886
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 723
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:11917211"
variation 730
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:150877602"
variation 731
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:61760204"
variation 742
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:373424435"
variation 759
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149578113"
variation 808
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:201476527"
variation 813
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:147276718"
variation 815
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200478981"
variation 816
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140845211"
variation 853
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:144601583"
variation 868
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:369493333"
exon 887..981
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 900
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="t"
/db_xref="dbSNP:35551105"
variation 924
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:201368964"
variation 928
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:147887335"
variation 947
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200404045"
variation 948
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:148480598"
variation 958
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199612648"
variation 965
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201751513"
variation 980
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:368347151"
exon 982..1169
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 994
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:75426377"
variation 1051
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200842164"
variation 1055
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:143703894"
variation 1088
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200851300"
variation 1089
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:115755648"
variation 1092
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:140837171"
exon 1170..1241
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 1205
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200580330"
variation 1240
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199508428"
exon 1242..1335
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 1251
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:141041980"
variation 1289
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:375364459"
variation 1315
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199512457"
exon 1336..1461
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 1347
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:140760133"
variation 1360
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377063095"
variation 1361
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:368929380"
variation 1455
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:114841413"
exon 1462..1615
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 1468
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200090282"
variation 1474
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:61750381"
variation 1491
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:140308745"
variation 1510
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:377643136"
variation 1518
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:202017744"
variation 1519
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200761055"
variation 1520
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200026200"
variation 1540
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:145234029"
variation 1549
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:373942034"
variation 1557
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:35132005"
variation 1564
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:114235967"
variation 1568
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200979122"
variation 1578
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:143824486"
variation 1601
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201920993"
variation 1602
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201509551"
exon 1616..1790
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 1627
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:144016604"
variation 1667
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:145621262"
variation 1678
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:147308215"
variation 1687
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139131420"
variation 1741
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:369543896"
exon 1791..1879
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 1800
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:185902975"
variation 1813
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:192477140"
variation 1861
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377320828"
exon 1880..2002
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 1925
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:374433568"
variation 1966
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:143157721"
variation 1972
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:147444783"
variation 1974
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:61750382"
variation 1977
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:377395498"
variation 1996
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370742776"
exon 2003..2029
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 2005
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149947980"
exon 2030..2173
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 2068
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:61733591"
variation 2087
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:111274613"
variation 2096
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200079140"
variation 2120
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:148697387"
variation 2128
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:368763882"
exon 2174..2340
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 2185
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:368608414"
variation 2186
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:373170651"
variation 2277
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:76353089"
variation 2333
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:184549998"
exon 2341..2494
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 2356
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199954201"
variation 2377
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:201209313"
variation 2464
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146739336"
variation 2488..2489
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="a"
/db_xref="dbSNP:35852624"
exon 2495..2579
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 2579
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140288498"
exon 2580..7933
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/inference="alignment:Splign:1.39.8"
variation 2590
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:187540816"
variation 2640
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371360955"
variation 2644
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199943847"
variation 2645
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:202177426"
variation 2646
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:144044913"
variation 2653
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="t"
/db_xref="dbSNP:34456126"
variation 2684
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201230992"
variation 2701
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200310337"
variation 2709
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:367912011"
variation 2725..2726
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="a"
/db_xref="dbSNP:201974472"
variation 2726..2727
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="t"
/db_xref="dbSNP:71300409"
variation 2750
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:75011052"
variation 2765
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:193041153"
variation 2820
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:114012075"
variation 2897
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:7646699"
variation 2970
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:111790665"
variation 3389..3390
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="a"
/db_xref="dbSNP:61465697"
variation 3440
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:75971703"
variation 3441
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146600298"
variation 3480
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:17195990"
variation 3485
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:184863751"
variation 3565
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:111295201"
variation 3622
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:368400568"
variation 3751
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:370933946"
variation 3966
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:141370768"
variation 4033
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:114520378"
variation 4063
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:143691431"
variation 4079
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:188400981"
variation 4085
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:151261728"
variation 4094
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:192681074"
variation 4136
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:114339410"
variation 4287
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:116146261"
variation 4336
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:113472679"
STS 4487..4606
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/standard_name="RH93958"
/db_xref="UniSTS:88187"
variation 4502
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:184674078"
variation 4550
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:140502990"
variation 4575..4577
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="aga"
/db_xref="dbSNP:144014392"
variation 4577..4579
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="aag"
/db_xref="dbSNP:71726872"
variation 4577
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:77642379"
variation 4578
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="aag"
/db_xref="dbSNP:78667934"
variation 4593
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:116718754"
variation 4695
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:187971271"
variation 4781
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:12486162"
variation 4936
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:113822484"
variation 4939
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:192542476"
variation 4969
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:72622569"
variation 4990
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:184584118"
variation 5025
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:189033728"
variation 5053
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:9814513"
variation 5067
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:138160305"
variation 5154
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:376502830"
variation 5183
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:371022756"
variation 5287
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:149105404"
variation 5289
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:60621113"
variation 5407
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:146223250"
variation 5442
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="t"
/db_xref="dbSNP:79270592"
variation 5454
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:370020175"
variation 5635
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:76174245"
STS 5748..5865
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/standard_name="D3S2768E"
/db_xref="UniSTS:150810"
variation 5841
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:138822337"
variation 5971
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:182106680"
variation 5981
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:375755665"
variation 5988
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:142841682"
variation 6136
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:79909042"
variation 6186
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:147997061"
variation 6226
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:141691568"
variation 6250
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:150502110"
variation 6265
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377264179"
variation 6269
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:186677724"
variation 6282
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:189995958"
variation 6299
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:139478047"
variation 6365
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:181256392"
variation 6418
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:376338210"
variation 6608
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:7624986"
variation 6680
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:144496906"
variation 6731
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:185317332"
variation 6751
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:146167066"
variation 6755
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:189683316"
variation 6849
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:371210506"
variation 6879
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:368580136"
variation 6963
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="g"
/replace="t"
/db_xref="dbSNP:201780791"
variation 7145
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:183440702"
variation 7226
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:10937010"
variation 7415
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:199517459"
variation 7444
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:143758106"
variation 7465
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="g"
/db_xref="dbSNP:3732993"
STS 7511..7647
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/standard_name="RH99087"
/db_xref="UniSTS:85603"
variation 7526
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="gg"
/db_xref="dbSNP:71762010"
variation 7665
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="g"
/db_xref="dbSNP:376483153"
variation 7713
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:145820187"
variation 7748
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:15241"
variation 7797
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:148946968"
variation 7822
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="c"
/db_xref="dbSNP:1045545"
variation 7871..7872
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace=""
/replace="c"
/db_xref="dbSNP:34291984"
variation 7904
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142884655"
variation 7929
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="c"
/replace="t"
/db_xref="dbSNP:186343183"
variation 7933
/gene="USP13"
/gene_synonym="IsoT-3; ISOT3"
/replace="a"
/replace="g"
/db_xref="dbSNP:191891819"
ORIGIN
gctcgctggcgccgccgccgccggcagaccccgcgctccggctccggctcggctcgctcggctccggtgcgcgccgaggccatgcagcgccggggcgccctgttcggcatgccgggcggcagcggaggcaggaagatggctgcaggagacatcggcgagctgctagtgccccacatgcccacgatccgcgtgcccaggtccggcgacagggtctacaagaacgagtgcgccttctcctacgactctcccaattctgaaggtggactctatgtatgcatgaatacatttttggcctttggaagggaacatgttgaaagacattttcgaaaaactggacagagtgtatacatgcacctgaaaagacatgtgcgagagaaggtaagaggggcgtctggtggagcgttaccaaaaaggaggaattccaagatttttttagatctagatactgatgacgatttaaatagcgacgattatgaatatgaagatgaagccaaacttgttatattcccagatcactatgaaatagcactaccaaatattgaggagttaccagccctggtaacaattgcttgtgatgcagttctcagctcaaaatctccatacagaaagcaggacccagacacgtgggaaaatgaattgccagtatctaaatatgccaacaacctcacccagctggacaatggagtcaggattcctccaagtggttggaagtgtgccagatgcgacctgcgagaaaacctctggttgaatctgactgacggctctgtcctgtgtggaaagtggttctttgacagctctgggggcaacgggcatgcgctggagcattacagagacatgggctacccactagccgtgaaactgggaaccatcactcctgacggggcagatgtttattcttttcaagaagaagaacctgttttggatcctcatttggccaagcacttagcgcattttggaattgatatgcttcatatgcatgggacagagaatgggctccaggacaatgacatcaagctgagggtcagtgagtgggaagtgatccaggagtcgggcacgaaactgaagccaatgtatggtcctggctacacgggtctgaagaacctgggcaacagctgctatctcagctctgtcatgcaggccatcttcagcatcccagaattccagagagcgtatgtaggaaaccttcccagaatatttgactactcgcctttagatccaacacaagatttcaacacacagatgactaagttaggacatggccttctctcaggccagtattcaaagcctccggtgaaatctgaactcattgaacaggtgatgaaggaggagcacaagccacagcagaacgggatctctccgcgcatgtttaaggcctttgtaagcaagagccacccggaattctcctctaacaggcagcaagatgcccaggaattcttcttgcacctggtgaatctagtagagaggaaccgcatcggctcagaaaacccaagcgatgtttttcgttttttggtggaagaacgcattcagtgctgtcagacccggaaagtccgctacacggagagggtggattacctgatgcagttacctgtggccatggaggcggcaaccaacaaggatgaactgatcgcttatgaactaacgagaagggaagcagaagcaaacagaagaccccttcctgagttggtacgtgccaagataccatttagtgcctgccttcaggccttctctgaaccagaaaatgttgatgatttctggagcagtgccctacaagcaaagtctgcgggtgtgaaaacatctcgctttgcttcattccctgaatacttggtagtgcagataaagaagttcacttttggtcttgactgggttcccaaaaaatttgatgtttctattgatatgccagacctacttgatatcaaccatctccgagccagggggttacagccaggagaggaagaacttccagacatcagcccccccatagtcattcctgatgactcaaaagatcgcctgatgaaccaattgatagacccatcagacatcgatgagtcatcagtgatgcagctggccgagatgggtttcccgctggaagcatgtcgcaaggctgtgtacttcactggaaatatgggcgccgaggtggccttcaactggatcattgttcacatggaagagccagattttgctgagccgctgaccatgcctggttatggaggggcagcttctgctggagcctctgtttttggtgcttctggactggataaccaacctccagaggaaatcgtagctatcatcacctccatgggatttcagcgaaatcaggctattcaggcactacgagcaacgaataataacctggaaagagcactggattggatctttagccaccctgagtttgaagaagacagtgattttgtgattgagatggagaataatgccaatgcaaacattatttctgaggccaagcccgaaggacctagagtcaaggatggatctggaacatatgagctatttgcattcatcagtcacatgggaacatccacaatgagtggtcattacatttgccatatcaaaaaggaaggaagatgggtgatttacaatgaccacaaagtttgtgcctcagaaaggccccctaaagacctgggctacatgtacttttaccgcaggataccaagctaaacctcaaatataaaaattggcgaaaagaagccatacgcctttttaatttgccaaaaaaaaaaagaagaagaagaagttgaaacaactagacatgaaggaatatatggggtatttatcgtttatttaaagagcacgatcagttgacaccttctgaaatagaactgagaagaaatttctattagtgatgatacactattatattgtagatagtttttataaatgttcaaaaagatgatgatatttaaaaacaaaaaaagtattcatattgctggtggaggatctgccatcagcacatcaaaaatggggatgtgcccccagccctctattttgctttgggggtcagtgatagtggcctctggagaaaccaaataatgtggccagtggtgtggccttacccacaacaaatgaaaagcccacttgtgtttcatatagaaaatcagcagttgggtggggctttatttgtgacataatttttttcatgacatacaataatttctgatgtatccatgtagatattatgctctgtccataatagagcctctgcaatgaaagatatttttaatttgtcacattaaaattcataatacgattgtgtgaatgtgtgtgagactgactgagagtgtgagacttttactagaaaagtgagtccactagaaaatctgtgacaagttggtttttaaagtctgaacagttgatattaagcatatctgaaaaaagcaagtaaatattttaacaaaactatgactcaggaaccttcgagaagattagttccccacttagatttttaaggagtaaaaagggctgagttatgcctttaagtgctgtcaagaattcacttgggtttgggacatttgctggtgtaatgctagatgcccacagcagcataatattgtactttgtcaaaggtaggtaaattctctgtttctcagcagccctttccccaaaaggtatggtgtttatttttagtaaaaatagctaatctctttttaccatctcacatgataactctttggagtcatgtcaagtgccccaaatttgtctgtgattttcccatctctgagctctttatctgcctccgtttccttgtttttctggggccagagtctcatctctgcctttttttggtgtatcaccttctgacttgccttcattgcttgtctgatgtgaccaacagtgtgatcttggacacactaaggattttagatgcaaagaaactttatacaacattatgaaagactatcctttccattttggttatttcagcattttagttgcaacctgggattagattagagtttccaacgtgatgaaaagtggaatgatagcattctataatttccataattttcctactggtccgtaccaaattctagagtctctggagttgctatttcagagtatttggtcaaacgaaaaagaatttattgctgtctgtttaacatgtatttgtttggttgaaaggatctttttagaaactgtaggaaaataaacagaaccaaccaggtgaaacaaagcacagacattgggttaggatgtagtgagttgtgaacaatcaggattctgggtgtgatgggggtccctgtctcataggtgatcctttggtgccatgtgaccgagagacatggtgtctaaggcccatggcctggagacctgggtgctgctcctagctgactgtggaccttgggcaagtccttcatccgtcctgtgcctcactgtcctcatctgaacaatggtatgatgacacctgccctctctttcaatcatgctttgaggatacagtgagattggttacagtgaaccttcaatgagtagaatgtggtatgccatggtgggttgtagtagatggtgctccctgccttttctcctctgttttcctcaatttgggaacaaatgagattggcagaaggagggagctcacggtgcagtacttttctaccaaagtgtgcccactggtgtcacctcctaatgttaacttggatttcctaaagcagtcccactctgttatgagagtcactgactcccgtggacatccccacagtaagcagccttacaaaatccagtccccttagggcagagtgagtgtcatagaataatgactccaaacccacgtcaaaaatggcttgttttcagcgatgttataaaacaaaggcctgttttttggaattgggggtgactgggtggtttggattgaaatgtggacaaagatagcatgtgtattttgaataaaataaaaattttgtaataaaacttttaaaaatcagtgatgtaaaatcaatatttaagactataggctataaattgtttgatttcattaactagcccttttgatgcctagacatgttgtaaaaaaattgtgctatggctgccttttcttctgccccacaacacaaagggctatttctacaaggcaaagttttgtatatgtgctattctttacttcagattgagagttgggaaaaactggagtaaataatgggtttcttacttgcttaaaagcatatttatatgtgtatctcaatatatacaaggcaggttcccctataaaagtctggaatgtactgcttaattttacacttgtgtagacacgattatttgtgactgaaaagtggaataacgtgtggattttgtcaactcattatcagtctgttagcagtcctctatgtgaggcatggtggtctaattgtgaaattctccctgtatatgggtgtctgtgtgaaagacagcactttcttcctgtaaatatcttttgatatccatttatgtagaattccaatgaatatgtctttggaaaaggtaatgtatcaaagtttttattttgccaattgatctaaatgcccatataactaatcagaaatccagtttggttcagattgggattttcttttaaagaaaaaaaaagtatgcagaaaagactattggaagaatcatgtgttagtgacactttacatcaacgttgcttcaatattttggaattgaccaggctgctttctcctacctgcaagagaatgtgcctgacatttcccagtgcttactttgggctataggaagtccagcggggatagctcgagcctcttgctccctgagtcatttattccctttacctgaacagagccttacctgcaattcatagtgagagcacctgggtctgtatcctgactccactctaagtgaggtgggactgaatcactgtacctctctgggccttttcatttgaaacaagtgggttagactagattagctccaaagtcctctcttgccctaacattttatttttattttcctgtggttaccactagggtctgacacgtaaaatgtgagggatcacttagaggtttggatgttatatttttgcattgttacagcttatactccccagttgaggacctgtgtcattcttagtggccccacgacccctctgtttgtattcctgctccacttatctatacttttttgggtaatcatcccactttttttttttcttgagatggagtctcgctgtgttgccaaggctggagtacagtggtgcaatctcagctcactgcagcctcctcccgggttcaagtgattctcctgcctcagcttcccaagtagctgggattactggcgcacgccactacgcccagctaatttttgtatttttagtagagacagggttttgccatgttggccaggctggtcttgaactcttgacctcaacctgcctcagcctcccaaagtgctgggattacacgcatgagctaccgcgtccagccccactttttttctactcttgaaaaaaacaactttctagtccatgaggtactttggctccatccccctcaaaaacaaaacaaaaaatccatttaaagtgtcctcctagaaaagcctcagaactgccttcaactacatctgtcacctttatagaatattttgaaattctggaagaggatgggaaacaaaattctaatttagctagagctgtgatccccaaataagtgctgacaaaattgtctaccacagaaaggccgtccttgtcatcttgtaggcatcactgctgctaaatcacatcagtacatgccttctgtggggagatggcagggggcaggggcaggaccaggggatgggattagataaagtgtgataatgtcctttagataaaagaaatcctacgctatagaacaaggttctgtactcttgagttggtgtctgagatcacctgcacagtgttacagagattttccactccataaatcactctaaaagagtttgcataagactcggtagacctgtgctattcaatgtggcagtcaacagccatatgtggcgatgactactcaaagtttggcttgttcaaatcgagactgtgttgtacacatacaatacacaccagattttgaaggcttggtaccaaaaaggaatttaaaatatttcaccaatatttcatattgataacatgctgaaatgacactattttggatgtactaagtaaaatattaacaatttaatatatttatataattgaaattaaaattcttttcacccatttttatttttttaaaaatgtggcccctaaagaacttcaaattagacatgtggataacgttatacttctattggacagccccactctagacttacatggtgtggggtaggcagtgaaatccgtaaataggaaacgcaattctgcaaagtatctaaatagacagaaacaacacaaatatttttgctggagtcaggagcactgtgaggcacagaacatctcccagaaagcagattttttttttctgccgaaaaaccaatatatatatgtatgatcccaattaaaagacaaaagcaaatgagccccaaactgcctgtcttcagctttgcctgggagctgctacctttgctcttctagcatcttctaggtaccaaggatattagccacttgagggtgttgggcatatttgtttcattgtaggcaaaatcctcttgtggtttcccctccccaggtattgttgagtctgttcaaagctgggtgtgttgaaacactgcacaaatcctgccactcttgatgtgccgcttgtctcagccttggcagaggctgagtctgttcctgtgcccacctgtccagcaggttttgatgttggctcctgaaagagtttgtatttattttattttgcactagtcacagttgttgttaaactgtatcaaatgttttgggagattatttgcctgagatggaaagagagatggatgatttattgcttcaattgttttaaattaaaagctattctcacaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:8975 -> Molecular function: GO:0004197 [cysteine-type endopeptidase activity] evidence: IMP
GeneID:8975 -> Molecular function: GO:0004221 [ubiquitin thiolesterase activity] evidence: IDA
GeneID:8975 -> Molecular function: GO:0004843 [ubiquitin-specific protease activity] evidence: IDA
GeneID:8975 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:8975 -> Molecular function: GO:0008242 [omega peptidase activity] evidence: IEA
GeneID:8975 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
GeneID:8975 -> Molecular function: GO:0031625 [ubiquitin protein ligase binding] evidence: IPI
GeneID:8975 -> Molecular function: GO:0043130 [ubiquitin binding] evidence: IDA
GeneID:8975 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IMP
GeneID:8975 -> Biological process: GO:0006511 [ubiquitin-dependent protein catabolic process] evidence: IEA
GeneID:8975 -> Biological process: GO:0006914 [autophagy] evidence: IEA
GeneID:8975 -> Biological process: GO:0008283 [cell proliferation] evidence: IMP
GeneID:8975 -> Biological process: GO:0010506 [regulation of autophagy] evidence: IDA
GeneID:8975 -> Biological process: GO:0030318 [melanocyte differentiation] evidence: TAS
GeneID:8975 -> Biological process: GO:0050821 [protein stabilization] evidence: IDA
GeneID:8975 -> Biological process: GO:0070536 [protein K63-linked deubiquitination] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_003931 -> EC 3.4.19.12
by
@meso_cacase at
DBCLS
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