Home |
Help |
Advanced search
2025-05-09 17:15:42, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001251971 7940 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens sperm associated antigen 9 (SPAG9), transcript variant
4, mRNA.
ACCESSION NM_001251971
VERSION NM_001251971.1 GI:354681994
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7940)
AUTHORS Yu,P., Yan,L., Zhang,H., Lin,X. and Zhao,X.
TITLE Expression and clinical significance of sperm-associated antigen 9
in patients with endometrial carcinoma
JOURNAL Int. J. Gynecol. Cancer 22 (1), 87-93 (2012)
PUBMED 22146769
REMARK GeneRIF: SPAG9 is positively expressed in endometrial cancer, and
with a high humoral immune response in patients. It may serve as a
new type of endometrial cancer markers for early detection,
diagnosis and treatment.
REFERENCE 2 (bases 1 to 7940)
AUTHORS Ando,K., Uemura,K., Kuzuya,A., Maesako,M., Asada-Utsugi,M.,
Kubota,M., Aoyagi,N., Yoshioka,K., Okawa,K., Inoue,H., Kawamata,J.,
Shimohama,S., Arai,T., Takahashi,R. and Kinoshita,A.
TITLE N-cadherin regulates p38 MAPK signaling via association with
JNK-associated leucine zipper protein: implications for
neurodegeneration in Alzheimer disease
JOURNAL J. Biol. Chem. 286 (9), 7619-7628 (2011)
PUBMED 21177868
REMARK GeneRIF: N-cadherin expression had an inhibitory effect on
JLP-mediated p38 MAPK signal activation by decreasing the
interaction between JLP and p38 MAPK
REFERENCE 3 (bases 1 to 7940)
AUTHORS Kanojia,D., Garg,M., Gupta,S., Gupta,A. and Suri,A.
TITLE Sperm-associated antigen 9 is a novel biomarker for colorectal
cancer and is involved in tumor growth and tumorigenicity
JOURNAL Am. J. Pathol. 178 (3), 1009-1020 (2011)
PUBMED 21356354
REMARK GeneRIF: These findings collectively suggest that SPAG9 may have a
role in tumor development and early spread.
REFERENCE 4 (bases 1 to 7940)
AUTHORS Kanojia,D., Garg,M., Saini,S., Agarwal,S., Kumar,R. and Suri,A.
TITLE Sperm associated antigen 9 expression and humoral response in
chronic myeloid leukemia
JOURNAL Leuk. Res. 34 (7), 858-863 (2010)
PUBMED 20138665
REMARK GeneRIF: SPAG9 mRNA& protein are expressed in CML patients (88%)
and in K562 & KCL-22 cells. 90% CML chronic-phase patients showed
humoral response against SPAG9.
REFERENCE 5 (bases 1 to 7940)
AUTHORS Garg,M., Kanojia,D., Suri,S., Gupta,S., Gupta,A. and Suri,A.
TITLE Sperm-associated antigen 9: a novel diagnostic marker for thyroid
cancer
JOURNAL J. Clin. Endocrinol. Metab. 94 (11), 4613-4618 (2009)
PUBMED 19820019
REMARK GeneRIF: Findings support a potential role for SPAG9 as diagnostic
biomarker as well as a possible therapeutic target in thyroid
cancer treatment.
REFERENCE 6 (bases 1 to 7940)
AUTHORS Bouwmeester,T., Bauch,A., Ruffner,H., Angrand,P.O., Bergamini,G.,
Croughton,K., Cruciat,C., Eberhard,D., Gagneur,J., Ghidelli,S.,
Hopf,C., Huhse,B., Mangano,R., Michon,A.M., Schirle,M., Schlegl,J.,
Schwab,M., Stein,M.A., Bauer,A., Casari,G., Drewes,G., Gavin,A.C.,
Jackson,D.B., Joberty,G., Neubauer,G., Rick,J., Kuster,B. and
Superti-Furga,G.
TITLE A physical and functional map of the human TNF-alpha/NF-kappa B
signal transduction pathway
JOURNAL Nat. Cell Biol. 6 (2), 97-105 (2004)
PUBMED 14743216
REMARK Erratum:[Nat Cell Biol. 2004 May;6(5):465]
REFERENCE 7 (bases 1 to 7940)
AUTHORS Yasuoka,H., Ihn,H., Medsger,T.A. Jr., Hirakata,M., Kawakami,Y.,
Ikeda,Y. and Kuwana,M.
TITLE A novel protein highly expressed in testis is overexpressed in
systemic sclerosis fibroblasts and targeted by autoantibodies
JOURNAL J. Immunol. 171 (12), 6883-6890 (2003)
PUBMED 14662895
REMARK GeneRIF: Testicular antigen PHET is an auutoantigen recognized by
sera from systemic sclerosis (SSc) patients with extensive fibrotic
changes; the autoantibody response to PHET is induced by ectopic
overexpression of PHET in dermal fibroblasts of SSc patients.
REFERENCE 8 (bases 1 to 7940)
AUTHORS Lee,C.M., Onesime,D., Reddy,C.D., Dhanasekaran,N. and Reddy,E.P.
TITLE JLP: A scaffolding protein that tethers JNK/p38MAPK signaling
modules and transcription factors
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (22), 14189-14194 (2002)
PUBMED 12391307
REFERENCE 9 (bases 1 to 7940)
AUTHORS Ichijo,H.
TITLE From receptors to stress-activated MAP kinases
JOURNAL Oncogene 18 (45), 6087-6093 (1999)
PUBMED 10557099
REMARK Review article
REFERENCE 10 (bases 1 to 7940)
AUTHORS Shankar,S., Mohapatra,B. and Suri,A.
TITLE Cloning of a novel human testis mRNA specifically expressed in
testicular haploid germ cells, having unique palindromic sequences
and encoding a leucine zipper dimerization motif
JOURNAL Biochem. Biophys. Res. Commun. 243 (2), 561-565 (1998)
PUBMED 9480848
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DC332810.1, AK295098.1 and
AC005920.1.
Summary: This gene encodes a member of the cancer testis antigen
gene family. The encoded protein functions as a scaffold protein
that structurally organizes mitogen-activated protein kinases and
mediates c-Jun-terminal kinase signaling. This protein also binds
to kinesin-1 and may be involved in microtubule-based membrane
transport. This protein may play a role in tumor growth and
development. Alternate splicing results in multiple transcript
variants. [provided by RefSeq, Oct 2011].
Transcript Variant: This variant (4) differs in the 5' UTR and has
multiple coding region differences, compared to variant 1. The
resulting isoform (4) has a distinct N-terminus and is shorter
compared to isoform 1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK295098.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-334 DC332810.1 1-334
335-694 AK295098.1 245-604
695-695 AC005920.1 121567-121567 c
696-3869 AK295098.1 606-3779
3870-7940 AC005920.1 62450-66520 c
FEATURES Location/Qualifiers
source 1..7940
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21.33"
gene 1..7940
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/note="sperm associated antigen 9"
/db_xref="GeneID:9043"
/db_xref="HGNC:14524"
/db_xref="MIM:605430"
exon 1..469
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
misc_feature 192..194
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/note="upstream in-frame stop codon"
CDS 309..3842
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/note="isoform 4 is encoded by transcript variant 4; sperm
surface protein; cancer/testis antigen 89;
JNK/SAPK-associated protein; JNK interacting protein;
c-Jun NH2-terminal kinase-associated leucine zipper
protein; Max-binding protein; C-Jun-amino-terminal
kinase-interacting protein 4; proliferation-inducing gene
6; lung cancer oncogene 4; sunday driver 1; protein highly
expressed in testis; human lung cancer oncogene 6 protein;
mitogen-activated protein kinase 8-interacting protein 4"
/codon_start=1
/product="C-Jun-amino-terminal kinase-interacting protein
4 isoform 4"
/protein_id="NP_001238900.1"
/db_xref="GI:354681995"
/db_xref="CCDS:CCDS58577.1"
/db_xref="GeneID:9043"
/db_xref="HGNC:14524"
/db_xref="MIM:605430"
/translation="
MSPGCMLLFVFGFVGGAVVINSAILVSLSVLLLVHFSISTGVPALTQNLPRILRKERPISLGIFPLPAGDGLLTPDAQKGGETPGSEQWKFQELSQPRSHTSLKDELSDVSQGGSKATTPASTANSDVATIPTDTPLKEENEGFVKVTDAPNKSEISKHIEVQVAQETRNVSTGSAENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNIVKNDLIAKVDELTCEKDVLQGELEAVKQAKLKLEEKNRELEEELRKARAEAEDARQKAKDDDDSDIPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFFSRLFSSSSNTTKKPEPPVNLKYNAPTSHVTPSVKKRSSTLSQLPGDKSKAFDFLSEETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGQGENKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYKDVAGLDTEGSKQRSASQSSLDKLDQELKEQQKELKNQEELSSLVWICTSTHSATKVLIIDAVQPGNILDSFTVCNSHVLCIASVPGARETDYPAGEDLSESGQVDKASLCGSMTSNSSAETDSLLGGITVVGCSAEGVTGAATSPSTNGASPVMDKPPEMEAENSEVDENVPTAEEATEATEGNAGSAEDTVDISQTGVYTEHVFTDPLGVQIPEDLSPVYQSSNDSDAYKDQISVLPNEQDLVREEAQKMSSLLPTMWLGAQNGCLYVHSSVAQWRKCLHSIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLSNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRKESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGVIISIPLTETVILHQGRLLGLRANKTSGVPGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVISPQSSSSGTDLTGDKAGPSAQEPGSQTPLKSMLVISGGEGYIDFRMGDEGGESELLGEDLPLEPSVTKAERSHLIVWQVMYGNE
"
exon 470..620
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
variation 606
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/replace="c"
/replace="g"
/db_xref="dbSNP:34733235"
exon 621..828
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 829..928
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 929..1050
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1051..1108
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1109..1261
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1262..1313
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1314..1444
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1445..1501
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1502..1675
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1676..1805
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1806..1895
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 1896..2063
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 2064..2235
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 2236..2454
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 2455..2650
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 2651..2776
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 2777..2857
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 2858..2925
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 2926..3074
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 3075..3246
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 3247..3360
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 3361..3399
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 3400..3576
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 3577..3726
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
exon 3727..7940
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/inference="alignment:Splign:1.39.8"
variation 4127
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/replace="a"
/replace="g"
/db_xref="dbSNP:8125"
STS 4211..4437
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="D17S2022"
/db_xref="UniSTS:17055"
STS 4244..4429
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="RH91778"
/db_xref="UniSTS:87223"
STS 4307..4430
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="D17S1393E"
/db_xref="UniSTS:150444"
polyA_signal 4438..4443
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
polyA_signal 4466..4471
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
polyA_site 4467
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
variation 4468
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/replace="a"
/replace="t"
/db_xref="dbSNP:1055303"
polyA_site 4491
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
STS 4785..4939
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="RH78073"
/db_xref="UniSTS:39895"
STS 4900..5028
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="SHGC-30378"
/db_xref="UniSTS:69757"
variation 5087
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/replace="a"
/replace="g"
/db_xref="dbSNP:1133791"
STS 5119..5256
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="D15S1390"
/db_xref="UniSTS:474340"
variation 5156
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/replace="c"
/replace="t"
/db_xref="dbSNP:1133792"
STS 5571..5655
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="D13S1553"
/db_xref="UniSTS:473482"
STS 5612..5700
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
variation 5743
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/replace="a"
/replace="g"
/db_xref="dbSNP:1133793"
variation 5783
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/replace="a"
/replace="g"
/db_xref="dbSNP:1055361"
STS 6706..6824
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="RH44968"
/db_xref="UniSTS:77832"
STS 7170..7345
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="RH12095"
/db_xref="UniSTS:26178"
polyA_signal 7358..7363
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
polyA_site 7380
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
STS 7692..7897
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="RH76125"
/db_xref="UniSTS:90431"
STS 7693..7898
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="WI-20746"
/db_xref="UniSTS:76680"
STS 7808..7897
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/standard_name="STS-Z41139"
/db_xref="UniSTS:61465"
variation 7939
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
/replace="a"
/replace="t"
/db_xref="dbSNP:3180903"
polyA_site 7940
/gene="SPAG9"
/gene_synonym="CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP;
PHET; PIG6"
ORIGIN
agatcttcaggcattgtagccaatgagctaagccaggactcttagtggaggggaaaatagttaataggctggctgtcgcttggggttgctgcataaatgctaggagcagcagctctatggttatgaggtggggagaacggaatgacgtcatcgcttgggagctgctgcaggatggagtggaaagctgctgctgatggcattgtttttgtggcagcaagctgaatgacagatcctcactacaaagatacccctttggcccccgtgtaggcctccttggttcgggtgtttcaccatgccagcacagcgccatgagtcctggatgcatgctgctgtttgtgtttggctttgttggcggggcggtggtcattaattctgctatcttagtatctctctctgttttgctgcttgtgcacttttctatttctaccggtgtgccagctctgacgcagaacctaccaaggatactcagaaaagaacgccctatatcattaggaattttcccattacctgctggagatggattgcttacacctgatgctcagaaaggaggagagacccctggatctgagcaatggaaatttcaggaattaagtcaaccacgttctcataccagcctgaaggatgagctttctgatgttagccaaggcggatctaaagctaccactccagcatcaacagctaattcagatgtggcaacaattcctactgatactcccttaaaggaagaaaacgaaggatttgtgaaggttacagatgcgccaaataaatcagagataagcaaacacattgaagtacaggtagcccaggaaactagaaatgtatctactggctctgctgaaaatgaagaaaagtcagaagttcaagcaatcatcgaatctactcctgagctggatatggacaaagatctcagtggatataaaggttcaagcactcccaccaaaggcatagagaacaaagcttttgatcgcaatacagaatctctctttgaagaactgtcttcagctggctcaggcctaataggagatgtggatgaaggagcagatttactaggaatgggtcgggaagttgagaatcttatattagaaaatacacaactgttggaaaccaaaaatgctttgaacatagtgaagaatgatttgatagcaaaagtggatgaactgacctgtgagaaagatgtgctgcaaggggaattggaggctgtgaagcaagccaaactgaaactagaggaaaagaacagagaattggaggaagagcttaggaaagctcgggcagaagctgaagatgcaaggcaaaaagcaaaagatgacgatgatagtgatattcccacagcccagaggaaacggtttactagagtagaaatggcccgtgttctcatggagcgaaaccagtataaagagagattgatggagcttcaggaagctgttcgatggacagagatgattcgggcatcacgagaaaatccagccatgcaggaaaaaaaaaggtcaagcatttggcagtttttcagccgacttttcagctcctcaagtaacacgactaagaagcctgaaccacctgttaatctgaagtacaatgcacccacgtctcatgttactccgtccgtcaagaaaagaagcagcaccttatctcagctccctggggataagtccaaagcctttgatttccttagtgaagaaactgaagctagtttagcctcacgcagagaacaaaagagagagcagtatcgtcaggtaaaagcacatgttcagaaggaagacggtagagtgcaggcttttggctggagtctgcctcagaagtacaaacaggtaaccaatggtcaaggtgaaaataagatgaaaaatttacctgtgcctgtctatctcagacctctggatgaaaaagatacatcaatgaagctgtggtgtgctgttggagtcaatttatctggtgggaagaccagagatggtggttctgttgttggagcaagtgtattttacaaggatgttgctggtttggatacagaaggcagtaaacagcgaagtgcctctcagagtagtttagataagttagatcaggaacttaaggaacagcagaaggagttaaaaaatcaagaagaattatccagtctagtttggatctgtaccagcactcattcggctacaaaagttcttattattgatgctgttcaacctggcaacatcctagacagtttcactgtttgcaactctcatgttctgtgcattgcaagtgtgccaggtgcacgagaaacagactaccctgcaggagaagatctttcagaatctggtcaggtagacaaagcatctttatgtggaagtatgacaagcaacagctcagcagagacagacagcctgttaggaggcatcacagtggttggttgttctgcagaaggtgtgacgggagctgccacttcccctagtacaaatggtgcttctccagtgatggataaaccaccagaaatggaagcagaaaatagtgaggttgatgaaaatgttccaacagcagaagaagcaactgaagctacagaagggaatgcggggtcagctgaagacacagtggacatctcccaaactggcgtctacacagagcatgtctttacagatcctttgggagttcagatcccagaagacctctccccagtgtatcagtcgagcaatgactcagatgcatataaagatcaaatatcagtactgccaaatgaacaagacttggtgagagaagaagcccagaaaatgagtagtcttttaccaactatgtggcttggagctcaaaatggctgtttgtatgtccattcatctgtagcccagtggaggaaatgtctccattccattaaacttaaagattcgattctcagtattgtacacgtgaagggaatcgtgttagtagccctggctgacggcacccttgcaatctttcacagaggagtggatgggcagtgggatttgtcaaactatcacctcttagaccttggacggcctcatcattccatccgttgcatgactgtggtacatgacaaagtctggtgtggctataggaacaaaatctatgtggtgcagccaaaggccatgaaaatagagaaatcttttgatgcacatcccaggaaggagagccaagtgcgacagcttgcgtgggtgggggatggcgtgtgggtctccattcgcttggattctacgctccgtctctatcatgcacacacttatcaacatctacaggatgtggacattgagccttatgtaagcaaaatgttaggtactggaaaactgggcttctcttttgtgagaattacagctcttatggtgtcttgtaatcgtttgtgggtggggacaggaaatggtgtcattatctccatcccattgacagaaaccgtaatcctccaccagggacgtttactggggctgagggcaaataaaacctcaggtgtaccaggaaatcgtcctggaagtgtaatccgtgtatatggtgatgaaaacagtgataaagtgactccagggacatttataccctattgttcaatggcacatgcacagctttgcttccatgggcaccgggatgctgtgaaattctttgtggcagtcccaggtcaagtcatcagcccacaaagtagcagtagtggcacggatctgacgggtgacaaagcagggccatctgcacaggagcctggtagtcagacgcccttgaagtctatgcttgtcatcagtggaggagagggctacatcgacttccgaatgggtgatgaaggtggagaatcagaacttcttggagaggatcttccacttgaaccttctgtcaccaaagcagaaaggagtcacttgatagtgtggcaagtgatgtatggcaatgagtgagcccatgggaaacaggtggagatggggaagccgtctcttctgcatggtttattttccctctatccttttatttaatgctcttttgtgagataagtttcaccacataatgtgtgagcattttttcctgttaactttatattacaaaatccgttctaccataacaatacagaggaactagctgtgttactgcaccagtgttataggtaacttcagtatattatgaacaaatcaaagaatgtttacttcctgcaaactggtgaattatagaaagcaatccagatgtggtttactctgccacagtctaatgtcattcacttcatttgatggggtcacttgttagctgtcactaataatggaattaatgggaaacacttgataaatgaaactgtaccgttaaatacaatagctgagttttccccagtgtattgtaaaattgacacacactaatacaagatggattatcaggatgtatctaaatgtcccgagagggttaaaagctaactgtaaattactttaactttcactttcaaatctgacaaatcttgtttatatggtatataaaactttgttttcatcagatttgggggggttttatattaaagaaattaagactacactatttaaataaacgtttcctgtttctgacttattagagctctaaagtttatgaggcctacttctctgaatattctgatgggttttttttgagaccagtctcattttcatactgacatgtctgaaagatttattatttataaagcttaggacatactctgggaagcttagaagatacttcagcactgggaggattttttaaaggaaatgtgttttgtatttcttgtaccagagaatggtgatgttgattgagttttttccatgtaaaaaatgtacttgtttgccaaatgttcctagattgctcttaacctgttaatacaagtaaaactgtagtggggatggagtctggcctaagtacagaatgagggatttaattagaaaagttattttcttttgttctgtatcaaactgcagaacagctatatacttggtattttgtacgtgaataacgttttagcttttgtgcccttttgagcttgaagggttatcctcaaaggggaaaactatgaaggggaagaagacaaacctaagataccataaagtaaaggttgacattacatattttcattcacaatgcccattaaaaaaaaaaaataggttgggcatggtggctcacgcctgtaatcccaacactttaggaggctgaggcagatggattgcttgagcccaggagttcaagaccagcctgggcaacatggcgaaaccctgtctctaccaaaaaaaaaaaacaaaataaattaaccgggtgtggtggcacatgcctgtagtcccagctacttgggaggctgaggtgggaggatgacctgggcccaggaggtggaggttgcagtgagccttgatagcaccactgcactccagcctgggtgacggagcaagaccctgtctcaaaacagacaaacaagcaaaaaatagattaaagtctggatttcactgattttcttgcttaataagttttttaaaaccacgatgctgcaattttttccctctcaagcttcttgaaaatgtgtgatttacccttttttatctattactctaggcaaagctaaatatgatttttttttttttttttgagacggagtctggctctgttgcccaggctggaatgcagtggtgcgatctcagctcactgcaacctccacctctcaggttcaagtagttctcctgcctcagcctcccaagtagctgggattacaggtgtgtgccaccctgcccagctaatttttgtatttttagtagagacagggtttcaccacattggccaggctggtctcaaactcctgacctcagatgatctacccgccttggcctcccgaagtgcttgaattacaggcgtgagcccccgcgccggtccgaagcaaagctaaatgtaattttatgtactgttttaacagtataaacctatgggataaaggcccccaatcatcagaaggactactgaaaagaaaagaaagcaaacgtagatgtcaaattgtctaaacattcttaagtaccactgattttttttttctggactattatacaaagatgtctgtaaaaagtataccagtggcttttatgcatatacacgattaggctagattgtgaagtacatgggatttcatgagccagaggaggcatttggatccattgggccacatgtgactataagcacattgtgtacacaataaaattgtagccactcatgtattaaaactgttttggtaaaagctgtattaaaagaataattttttgcttgagctacttagtcacttttttgcagggcaccaaaatgtaggctacttttccatagcttgtttgctatgtttttatttcatcttaaatctgagccatttttggcaatatcttttaaaaaatcattattaaacatttattggaaatgttgtatagattcacaagaaagagacaccaaagtgtttgggaattttaatcccaagaagtaaacatcccagagtcagatcccatttgctgttgttcagccatgtttgtatgactgaatgtaatttaggaaatcaggagttagagatgaaaaatacaaacatgtcaaatggttgtaattgctttttttgaacttactggctttaacttaagtaatataggtgtgtagttgttttatctaaagatgtcagattatctgtggccctgttaattaactgcagggaccagagagaggacaaaaatgcctgtataatttgctttaaaggcttgtccttatgtttgtaatttcagttaaatattttctacagattgcttcacttcccctttcccccaataacaagttcatattcttgtaatgtttactttggtcaacgtggtaatttttggaagaaaatgccaaaatgtaagcttctcacaagcagcaaaggaatgtaactgcctgtagctaccacatcaagggagagaagaggcttgcgtactttgggttgatctcactgtacaaaaaaagtgtacccctattggaagaaataaggaatacttgaaggtttctcctttttttacacttgagtcatgtgcaaggttgaaccatatgaaattgccagtgttcaaccattgctgatctgcaaaagcgacaatatcatatgcctcaacctaacacttactcttaaatgcaggttaaaatctctgtgaggcaaagggataatattctctaggaactcacttttgagagtatttttctctaacccatgtggatctaaattttaaaaataggaatgaatctcttaattgcagcttgtggagagtataaaacattttgagcacaatatgcagcacataacttttcagattgtgtttgcatagaaaaggttaaaatcaattctttcagttactgtattgttcatttcttgtaaaggtcttcctacatttgagacgagaccctttaacataggctgccttagtaacaaaataaaacagatgtgtcataatattaactgtcctaaagaacatgtgtcttgcaaatgccatggaactgaatatttatttccttgtgagtattatgaccgttaccaaaggactcaaccagatttagggctcttcttaattgatcatgttcagaaagggactcatttggtcccactttgtaacatgggaagagtagaagagaaaattaaatgtggaaatcataaatgcttttctaacagggttatgctattctgtaacactaaatgtctgtcttttctcttaaaagattaagttttattaattttgtcatacatttctctatttgaatatatcttaaccattttatgttccaaattcgttttttgtccaagacattctatcagaattttacttgcctctataatctgaaaaatgggttctagaatgtcccacttgctgtctcttagaggctgagcttcatttctatgagcaaagagctcatttagcaatgtagttatttcagtatttatttctattatggaatccctggggttcagaatgtaactttgtacatgagatatatataaatatgtatatgaacatgta
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9043 -> Molecular function: GO:0008432 [JUN kinase binding] evidence: IEA
GeneID:9043 -> Molecular function: GO:0019894 [kinesin binding] evidence: IEA
GeneID:9043 -> Molecular function: GO:0048273 [mitogen-activated protein kinase p38 binding] evidence: IEA
GeneID:9043 -> Biological process: GO:0007257 [activation of JUN kinase activity] evidence: IEA
GeneID:9043 -> Biological process: GO:0007283 [spermatogenesis] evidence: TAS
GeneID:9043 -> Biological process: GO:0030335 [positive regulation of cell migration] evidence: IMP
GeneID:9043 -> Biological process: GO:0042147 [retrograde transport, endosome to Golgi] evidence: IDA
GeneID:9043 -> Biological process: GO:0042692 [muscle cell differentiation] evidence: TAS
GeneID:9043 -> Biological process: GO:0045666 [positive regulation of neuron differentiation] evidence: IEA
GeneID:9043 -> Biological process: GO:0051146 [striated muscle cell differentiation] evidence: IEA
GeneID:9043 -> Biological process: GO:0051149 [positive regulation of muscle cell differentiation] evidence: TAS
GeneID:9043 -> Biological process: GO:0051260 [protein homooligomerization] evidence: IEA
GeneID:9043 -> Biological process: GO:0090074 [negative regulation of protein homodimerization activity] evidence: IEA
GeneID:9043 -> Cellular component: GO:0001669 [acrosomal vesicle] evidence: IEA
GeneID:9043 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:9043 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:9043 -> Cellular component: GO:0016021 [integral to membrane] evidence: TAS
GeneID:9043 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.