Home |
Help |
Advanced search
2025-05-09 17:35:47, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001137668 6649 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens caspase 8 associated protein 2 (CASP8AP2), transcript
variant 3, mRNA.
ACCESSION NM_001137668
VERSION NM_001137668.1 GI:212549531
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6649)
AUTHORS Yang,X.C., Sabath,I., Debski,J., Kaus-Drobek,M., Dadlez,M.,
Marzluff,W.F. and Dominski,Z.
TITLE A complex containing the CPSF73 endonuclease and other
polyadenylation factors associates with U7 snRNP and is recruited
to histone pre-mRNA for 3'-end processing
JOURNAL Mol. Cell. Biol. 33 (1), 28-37 (2013)
PUBMED 23071092
REMARK GeneRIF: FLASH/Lsm11 complex bind a unique combination of
polyadenylation factors
REFERENCE 2 (bases 1 to 6649)
AUTHORS Lee,K.D., Pai,M.Y., Hsu,C.C., Chen,C.C., Chen,Y.L., Chu,P.Y.,
Lee,C.H., Chen,L.T., Chang,J.Y., Huang,T.H., Hsiao,S.H. and
Leu,Y.W.
TITLE Targeted Casp8AP2 methylation increases drug resistance in
mesenchymal stem cells and cancer cells
JOURNAL Biochem. Biophys. Res. Commun. 422 (4), 578-585 (2012)
PUBMED 22595458
REMARK GeneRIF: These data demonstrate that methylation within the
Casp8AP2 promoter correlates with the development of drug
resistance and might serve as a biomarker and treatment target for
drug resistance in cancer cells.
REFERENCE 3 (bases 1 to 6649)
AUTHORS De Cola,A., Bongiorno-Borbone,L., Bianchi,E., Barcaroli,D.,
Carletti,E., Knight,R.A., Di Ilio,C., Melino,G., Sette,C. and De
Laurenzi,V.
TITLE FLASH is essential during early embryogenesis and cooperates with
p73 to regulate histone gene transcription
JOURNAL Oncogene 31 (5), 573-582 (2012)
PUBMED 21725362
REMARK GeneRIF: Data show that show that the transcription factor p73
binds to Flice-Associated Huge Protein (FLASH) and is part of the
complex that regulates histone gene transcription.
REFERENCE 4 (bases 1 to 6649)
AUTHORS Chen,S., Evans,H.G. and Evans,D.R.
TITLE FLASH knockdown sensitizes cells to Fas-mediated apoptosis via
down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip
short
JOURNAL PLoS ONE 7 (3), E32971 (2012)
PUBMED 22427918
REMARK GeneRIF: FLASH knockdown in HT1080 mutant cells defective in p53
did not significantly accelerate Fas mediated apoptosis indicating
that the effect was dependent on functional p53.
REFERENCE 5 (bases 1 to 6649)
AUTHORS Hummon,A.B., Pitt,J.J., Camps,J., Emons,G., Skube,S.B., Huppi,K.,
Jones,T.L., Beissbarth,T., Kramer,F., Grade,M.,
Difilippantonio,M.J., Ried,T. and Caplen,N.J.
TITLE Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional
deregulation of the replication-dependent histone genes and
extensive effects on the transcriptome of colorectal cancer cells
JOURNAL Mol. Cancer 11, 1 (2012)
PUBMED 22216762
REMARK GeneRIF: This study further defines the role CASP8AP2/FLASH plays
in the regulating expression of the replication-dependent histones
and shows that its LOF results in broad and reproducible effects on
the transcriptome of colorectal cancer cells
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 6649)
AUTHORS Jun,J.I., Chung,C.W., Lee,H.J., Pyo,J.O., Lee,K.N., Kim,N.S.,
Kim,Y.S., Yoo,H.S., Lee,T.H., Kim,E. and Jung,Y.K.
TITLE Role of FLASH in caspase-8-mediated activation of NF-kappaB:
dominant-negative function of FLASH mutant in NF-kappaB signaling
pathway
JOURNAL Oncogene 24 (4), 688-696 (2005)
PUBMED 15592525
REMARK GeneRIF: endogenous caspase-8 mediates tumor necrosis
factor-alpha-induced activation of NF-kappaB via FLASH
REFERENCE 7 (bases 1 to 6649)
AUTHORS Kino,T. and Chrousos,G.P.
TITLE Tumor necrosis factor alpha receptor- and Fas-associated FLASH
inhibit transcriptional activity of the glucocorticoid receptor by
binding to and interfering with its interaction with p160 type
nuclear receptor coactivators
JOURNAL J. Biol. Chem. 278 (5), 3023-3029 (2003)
PUBMED 12477726
REFERENCE 8 (bases 1 to 6649)
AUTHORS Choi,Y.H., Kim,K.B., Kim,H.H., Hong,G.S., Kwon,Y.K., Chung,C.W.,
Park,Y.M., Shen,Z.J., Kim,B.J., Lee,S.Y. and Jung,Y.K.
TITLE FLASH coordinates NF-kappa B activity via TRAF2
JOURNAL J. Biol. Chem. 276 (27), 25073-25077 (2001)
PUBMED 11340079
REFERENCE 9 (bases 1 to 6649)
AUTHORS Koonin,E.V., Aravind,L., Hofmann,K., Tschopp,J. and Dixit,V.M.
TITLE Apoptosis. Searching for FLASH domains
JOURNAL Nature 401 (6754), 662 (1999)
PUBMED 10537104
REFERENCE 10 (bases 1 to 6649)
AUTHORS Imai,Y., Kimura,T., Murakami,A., Yajima,N., Sakamaki,K. and
Yonehara,S.
TITLE The CED-4-homologous protein FLASH is involved in Fas-mediated
activation of caspase-8 during apoptosis
JOURNAL Nature 398 (6730), 777-785 (1999)
PUBMED 10235259
REMARK Erratum:[Nature 1999 Jul 1;400(6739):89]
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BP192859.1, BC132828.1 and
AF154415.1.
Summary: This protein is highly similar to FLASH, a mouse apoptotic
protein identified by its interaction with the death-effector
domain (DED) of caspase 8. Studies of FLASH protein suggested that
this protein may be a component of the death-inducing signaling
complex that includes Fas receptor, Fas-binding adapter FADD, and
caspase 8, and plays a regulatory role in Fas-mediated apoptosis.
Alternative splicing results in multiple transcript variants
encoding the same protein.[provided by RefSeq, Nov 2008].
Transcript Variant: This variant (3) differs in the 5' UTR,
compared to variant 1.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
CDS exon combination :: AF154415.1, AF164678.2 [ECO:0000331]
RNAseq introns :: mixed/partial sample support ERS025084,
ERS025086 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-35 BP192859.1 1-35
36-6539 BC132828.1 16-6519
6540-6649 AF154415.1 6673-6782
FEATURES Location/Qualifiers
source 1..6649
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q15"
gene 1..6649
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/note="caspase 8 associated protein 2"
/db_xref="GeneID:9994"
/db_xref="HGNC:1510"
/db_xref="MIM:606880"
variation 4
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:375731771"
variation 10
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:368340936"
variation 24
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:183190155"
misc_feature 40..42
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/note="upstream in-frame stop codon"
variation 55
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:371341158"
CDS 64..6012
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/note="FLICE associated huge; CASP8 associated protein 2;
FLICE-associated huge protein; human FLASH; FLASH homolog
RIP25"
/codon_start=1
/product="CASP8-associated protein 2"
/protein_id="NP_001131140.1"
/db_xref="GI:212549532"
/db_xref="GeneID:9994"
/db_xref="HGNC:1510"
/db_xref="MIM:606880"
/translation="
MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEEILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIKTARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHRAKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSNEDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTESKSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKSQDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRDKSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESKEENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAMKAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQVKTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLLVRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTDVSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSEDNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDNSVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSKSQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVSADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTSSLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLIKHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLDYLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSEDPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPSTPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDLAVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSMMPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQTQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLPNTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDLTQDASSEAKSEGNHPALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTESPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSKCR
"
misc_feature 67..69
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/experiment="experimental evidence, no additional details
recorded"
/note="N-acetylalanine; propagated from
UniProtKB/Swiss-Prot (Q9UKL3.1); acetylation site"
misc_feature 121..123
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UKL3.1); phosphorylation site"
misc_feature 5110..5124
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UKL3.1);
Region: SUMO interaction motif 1 (SIM), mediates the
binding to polysumoylated substrates (By similarity)"
misc_feature 5188..6009
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UKL3.1);
Region: NCOA2-binding"
misc_feature 5272..5286
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UKL3.1);
Region: SUMO interaction motif 2 (SIM), mediates the
binding to polysumoylated substrates (By similarity)"
misc_feature 5443..5457
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UKL3.1);
Region: SUMO interaction motif 3 (SIM), mediates the
binding to polysumoylated substrates (By similarity)"
misc_feature 5809..6003
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/note="Caspase 8-associated protein 2 myb-like domain;
Region: CASP8AP2; cd12202"
/db_xref="CDD:213401"
variation 72
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:371635635"
variation 111
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:35891026"
variation 114
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:376288172"
variation 139
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:377117590"
variation 208
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:138471825"
variation 225
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:374871939"
variation 237
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:369309364"
variation 342
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:369328"
variation 411
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:375845338"
variation 414
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:370454326"
variation 558
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:191794738"
variation 574
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:375746744"
variation 580
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:371046529"
variation 655
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:79485882"
variation 695
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:199979891"
variation 716
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:115337779"
variation 718
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:374867724"
variation 726
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:182729426"
variation 735
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:372111972"
variation 749
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:377049861"
variation 772
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:368353175"
variation 773
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:202238236"
variation 791
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:376835324"
variation 808
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:369918159"
variation 833
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:371653827"
variation 834
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:116832209"
variation 851
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:200917530"
variation 873
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:201596073"
variation 875
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:369118984"
variation 933
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:3734656"
variation 934
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:376169756"
variation 935
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:369927994"
variation 957
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:373400557"
variation 972
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:377422956"
variation 1042
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:200248550"
variation 1064
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:374722055"
variation 1092
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:9444715"
variation 1110
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:370574439"
variation 1120
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:375447849"
variation 1168
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:368346657"
variation 1179
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:372317117"
variation 1227
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:374277382"
variation 1323
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:75673851"
variation 1367
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:74395498"
variation 1400
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:187658864"
variation 1405
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:372268202"
variation 1406
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:374708182"
variation 1415
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:202104748"
variation 1419
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:34701151"
variation 1435
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:201785439"
variation 1494
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:192787612"
variation 1587
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:369303003"
variation 1613
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:200323558"
variation 1669
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:376777596"
variation 1675
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:370049023"
variation 1681
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:374581994"
variation 1731
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:377395999"
variation 1741
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:370348129"
variation 1779
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:370445193"
variation 1781
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:200220681"
variation 1803
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:377095494"
variation 1853
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:370562618"
variation 1931
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:375044202"
variation 1933
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:368459977"
variation 1979
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:372157483"
variation 2001
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:374796247"
variation 2002
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:139622677"
variation 2026
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:367672377"
variation 2028
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:371194420"
variation 2043
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:375013992"
variation 2049
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:368221756"
variation 2065
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:201489639"
variation 2085
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:376398807"
variation 2118
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:369747236"
variation 2133
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:374435750"
variation 2175
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:373095386"
variation 2199
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:185478571"
variation 2213
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:369938492"
variation 2266
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:199531988"
variation 2310
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:376213760"
variation 2330
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:370683344"
variation 2360
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:189475790"
variation 2435
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:118038939"
variation 2447
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:377330360"
variation 2454
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:3799895"
variation 2460
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:370853193"
variation 2470
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:374310883"
variation 2495
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:373335807"
variation 2586
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:191911199"
variation 2595
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:201271265"
variation 2601
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:368553205"
variation 2627
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:371069501"
variation 2666
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:184335133"
variation 2686
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:201494268"
variation 2740
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:202224866"
variation 2780
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:137945652"
variation 2813
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:199818755"
variation 2917
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:201306147"
variation 2932
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:368026528"
variation 2952..2953
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace=""
/replace="c"
/db_xref="dbSNP:34572105"
variation 2978
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:117850701"
variation 3002
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:149473817"
variation 3019
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:201974982"
variation 3023
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:376299045"
variation 3042
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:369795421"
variation 3059
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:114897724"
variation 3125
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:375785540"
variation 3191
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:369132664"
variation 3222
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:370730058"
STS 3451..3607
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/standard_name="STS-H50583"
/db_xref="UniSTS:2284"
variation 3466
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:373329038"
variation 3503
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:1064002"
variation 3531
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:143076875"
variation 3568
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:182864217"
variation 3695
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:41273333"
variation 3721
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:116614248"
variation 3775
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:201597048"
variation 3777
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:199918891"
variation 3779
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:73752819"
variation 3782
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:201506096"
variation 3810
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:376295745"
variation 3817
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:200866261"
variation 3818
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:374748337"
variation 3834
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:369576046"
variation 3864
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:367664392"
variation 3877
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:370073401"
variation 3879
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:374343288"
variation 3907
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:186180164"
variation 3914
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:148256815"
variation 3923
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:375610839"
variation 3930
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:141249173"
variation 3956
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:372787304"
variation 3957
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:375991831"
variation 4000
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:370120781"
variation 4020
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:371257885"
variation 4026
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:374774067"
variation 4079
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:369180336"
variation 4085
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:78396072"
variation 4116
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:147437828"
variation 4123
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:376211225"
variation 4200
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:369714914"
variation 4233
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:373655186"
variation 4368
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:376852526"
variation 4450
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:139736386"
variation 4451
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:143016644"
variation 4455
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:371559146"
variation 4489
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:190118214"
variation 4601
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:75601500"
variation 4656
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:60966143"
variation 4704
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:200433993"
variation 4761..4778
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace=""
/replace="gacatctttgcccagaca"
/db_xref="dbSNP:202116886"
variation 4766
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:202101805"
variation 4768
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:200213073"
variation 4774
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:201189413"
variation 4777
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:202111256"
variation 4779
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:199694900"
variation 4780
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:200862023"
variation 4781
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:201534830"
variation 4782
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:199515704"
variation 4901
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:139983441"
variation 4930
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:150022229"
variation 4954
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:369757511"
variation 4980
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:368260598"
variation 4998
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:371881005"
variation 5011
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:111766212"
variation 5030
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:375182927"
variation 5038
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:3799896"
variation 5041
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:372893351"
variation 5098..5099
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace=""
/replace="t"
/db_xref="dbSNP:34373654"
variation 5105
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:374695928"
variation 5113
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:200556402"
variation 5185
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:369072391"
variation 5186
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:371594163"
variation 5201
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:199714955"
variation 5205
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:369451328"
variation 5223
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:200853389"
variation 5246
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:377357235"
variation 5267
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:369858460"
variation 5269
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:117650507"
variation 5289
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:377396142"
variation 5300
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:370442854"
variation 5361
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:374893112"
variation 5367
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:377482246"
variation 5372
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:73752820"
variation 5382
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:374232968"
variation 5389
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:368605777"
variation 5399
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:371085535"
variation 5430
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:374618973"
variation 5463
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:368658707"
STS 5465..5702
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/standard_name="SHGC-52865"
/db_xref="UniSTS:38874"
variation 5484
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:371166110"
variation 5488
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:200564116"
variation 5578
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:201549866"
variation 5581
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:200157861"
variation 5669
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:1062121"
variation 5714
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:199771380"
variation 5740
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:182937785"
variation 5761
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:367942163"
variation 5795
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:372229978"
variation 5878
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:369939894"
variation 5894
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:200753477"
variation 5928
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="c"
/db_xref="dbSNP:374433157"
variation 6013
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:370975833"
variation 6038
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="t"
/db_xref="dbSNP:376095529"
variation 6048
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:367794675"
variation 6085
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="t"
/db_xref="dbSNP:11752373"
variation 6152
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:368628751"
variation 6160
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:112756481"
variation 6198
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="c"
/replace="g"
/db_xref="dbSNP:371344448"
variation 6357
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:372563597"
variation 6377
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="g"
/replace="t"
/db_xref="dbSNP:370145460"
STS 6406..6547
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/standard_name="RH47433"
/db_xref="UniSTS:49695"
variation 6487
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace="a"
/replace="g"
/db_xref="dbSNP:142161883"
variation 6554..6555
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
/replace=""
/replace="tt"
/db_xref="dbSNP:71864478"
polyA_signal 6613..6618
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
polyA_site 6639
/gene="CASP8AP2"
/gene_synonym="CED-4; FLASH; RIP25"
ORIGIN
aaaggaaccgggttgtcttgggccgggcagggcgggtggtgactctcaaaaggaaataggatcatggcagcagatgatgacaatggtgatggaacaagtttatttgatgtcttttctgcttctcctcttaagaacaatgatgaaggctcactggacatatacgctgggttggacagtgctgtttctgacagcgcttccaaatcctgtgtaccatcaagaaattgtttggacttatatgaagagatcctgactgaagaaggaactgcaaaggaggcaacatataatgatttgcaagtagaatatggaaaatgtcaactacaaatgaaagagctgatgaaaaaatttaaagaaatacagacacagaatttcagcttaataaacgaaaaccagtctcttaagaagaatatttcagcacttatcaaaactgccagagtggaaataaaccgcaaggatgaagaaataagtaatcttcaccaaagattgtctgagtttccacattttcgaaataatcataaaactgcaaggacatttgatacagttaaaacaaaagatcttaaatctagatctccacatttggatgattgttcaaagactgatcacagagctaaaagtgatgtttctaaagatgtacatcatagcacttcactgccaaatctggaaaaggaaggaaaaccacattctgataaaaggagtacttcacatttacctacatctgttgagaaacactgcactaatggtgtttggtcacgttctcattatcaggttggcgagggtagctcaaatgaggatagtagaagaggaagaaaagatattagacatagccagtttaacagaggaactgaaagagtacgaaaagacttaagtactggctgtggtgatggtgaaccaaggatattggaggctagtcaaaggctacaaggacatcctgagaaatatggtaaaggtgaaccaaagactgaaagcaaaagttcgaagtttaaaagtaactcagattctgactataaaggtgaacgcattaactcttcttgggagaaagagacccctggagaaaggtcacacagtcgagtagactctcaaagtgacaaaaaactagaaagacaaagtgaaagatcacaaaatataaataggaaagaagttaaatcacaagacaaagaagaaagaaaagttgatcaaaaacctaaatcagtagtaaaggaccaagatcactggagaagatctgaacgagcatcacttcctcattccaagaatgaaataacattttctcataattcaagtaaataccatctagaagagagaagaggatgggaagattgtaaaagagacaagagtgtaaacagtcatagttttcaagatggaagatgtccatcttctctttcaaacagtagaactcacaaaaacattgactctaaggaagttgatgccatgcatcagtgggaaaatacacctttaaaagcagaaagacatagaactgaagataagaggaaaagagaacaagaaagcaaagaagaaaataggcatattagaaatgaaaaaagagtacctacagaacatttgcagaagactaataaggaaactaagaaaaccactactgatttaaagaaacagaatgaaccaaagactgataagggagaagtccttgataatggtgtttctgaaggagcagataataaagagcttgcaatgaaagctgagagtggtccaaatgaaacaaaaaacaaggacctaaaattgagttttatgaaaaaattgaacttaactctttctcctgctaaaaagcaacctgtttcccaggataatcagcataaaataactgatattcccaagtccagtggtgtatgtgattcagagtcttcaatgcaagttaaaacagtggcatatgttccctccataagtgaacatatcttgggggaagcagctgtcagtgaacataccatgggggaaaccaagtcaacgttattggaaccaaaggttgctcttctagcagtgactgaacccaggatcggtatctcagaaaccaacaaggaagacgaaaatagtttgttagttaggtctgttgacaatactatgcattgtgaagagcccatttgtggtacagagacttccttcccatctcctatggaaatacaacagacagaatccttgtttccatcaacaggaatgaaacaaaccattaataatggaagggcagcagctcctgtggtaatggatgtattacaaacagatgtgtctcaaaactttggcttggaattggataccaaaagaaatgataattcagattattgtggtatttctgaaggtatggagatgaaggtggcactttcaacaacagtgagtgaaaccactgaaagcattttgcagccttcaattgaggaagctgatattttgccaataatgctttcagaagataataacccaaaatttgagccttctgttatagttacaccactggttgagagtaagtcgtgtcatctggagccttgcttacctaaagagactctagattcttcacttcagcagactgagttaatggaccacagaatggcaactggtgaaacaaactcagtatatcatgatgatgataactcggttttgagcattgaccttaatcacctgagacctattccagaagccatcagtcctctgaatagtccagtgagacctgtagcaaaagttcttagaaatgaaagcccacctcaagttccagtgtataataacagtcataaagatgtgtttttaccaaattcagctcattctacctctaagagtcagtctgatctcaataaggaaaatcaaaagccaatttacaaatctgacaaatgtacagaagcagacacatgtaagaattcaccattagatgaattagaagaaggagaaattagaagtgatagtgaaacatctaaaccacaagaaagttttgaaaaaaattccaaacgtagagtgtcagctgatgtgcggaagtcaaagactatcccacgacgtgggaaaagtactgtgtgtttagataaagacagtaggaaaacacatgtaagaatccatcagaccaataacaaatggaataaaagacctgataaatctagcagatcttcaaaaacagagaagaaagataaagtgatgagcacttccagcttggaaaaaatagttccaattattgctgtaccctcttctgaacaagagatcatgcacatgttacgaatgataagaaaacatgtaagaaaaaattatatgaaattcaaggcaaaattttcattaatacaatttcacagaattattgagtcagcaattttgagttttacatctttaattaaacatctcaacttacacaaaatctctaagtcagtgactaccttacagaagaatctctgtgatattatagagtctaaacttaagcaagttaaaaagaatggcatagttgatcgtttatttgaacagcaactaccagatatgaaaaaaaaattgtggaagtttgtagatgaccaacttgattatttgtttgcaaagcttaagaaaatcttagtatgtgattccaaaagctttggaagagatagtgatgaaggcaaacttgaaaaaacaagtaaacagaatgcacagtattcaaatagtcagaaaaggagtgtggacaactccaacagagaattgctgaaagaaaaattatcaaaatcagaagaccctgttcattataagtctttagtgggatgtaaaaaatctgaggaaaattatcaagaccaaaataactccagtattaacactgtaaagcatgacattaaaaaaaattttaacatctgctttgataatataaagaactctcaatccgaagagcgctccttggaagtacactgtccaagcaccccaaagtcagaaaaaaacgaaggaagcagcatagaggatgcacagacatcccagcatgcaactttgaagccagaacgaagtttcgagattcttaccgaacagcaagcatcgagccttacttttaatttagtgagtgatgcacaaatgggtgaaatatttaaaagtttgttgcaaggttctgatcttttagacagcagtgttaactgtactgaaaaaagtgagtgggagttaaagactccagagaagcagctgctagagactcttaagtgcgagtctataccagcttgtacaacagaagagctagtttcaggggtggcttctccatgtcctaaaatgattagtgatgataattggtcattattatcatctgaaaaaggtccatctctgtcttcagggctttcattgccggttcatcctgatgtgttggatgaaagttgtatgtttgaagtgtctactaacctacctttaagtaaagataatgtgtgtagtgtagaaaagagcaagccctgcgtttcttccatacttcttgaagatctagcagtctctttaacagtaccatcgcctctgaagtcagatggtcatctcagttttttaaagcctgatatgtcgtccagttcaactcctgaagaagtcattagtgctcattttagtgaagatgccttacttgaggaagaggatgcatctgagcaagatattcatttagctctggagtctgataattcaagcagtaaatcaagttgttcttcttcctggacaagccgatctgttgctccaggctttcagtaccaccctaatctacctatgcatgccgtcataatggaaaagtccaatgatcatttcattgtgaaaatacgacgtgcaacaccatctacctcttctggccttaaacagagtatgatgcctgatgaattattgacatctttgcccagacatggaaaggaagctgatgaaggaccagagaaagaatatatttcatgtcagaacacagtttttaaatctgtggaggaattggaaaactccaacaaaaatgttgatggcagcaagtcaactcatgaagaacagagctctatgatacaaacacaggttcctgatatatatgaatttcttaaagatgcttcagataagatgggtcatagtgatgaagtggctgatgaatgtttcaaattgcatcaagtatgggaaacaaaagtgcctgaaagcattgaagaattgccttcaatggaagaaatctcacactctgttggggaacatcttccaaacacatacgtagatctaacgaaagatccagtcactgaaaccaaaaacttgggggaattcatagaagtaacagttttacatattgatcagttgggatgttctggaggcaatttaaatcagagtgctcaaatattagacaattctttgcaggctgatactgtaggtgcttttattgatttgacacaagatgcttcaagtgaggctaaaagtgaaggtaatcatcctgcattagctgtggaagacttgggatgtggggtgatacaggtagatgaagataattgtaaggaagaaaaggcacaagtggcaaacaggcctttaaaatgcattgttgaggaaacctatatcgacttgaccacagaatctcccagttcatgtgaagtaaaaaaagatgagttaaaatcagagccaggatcaaattgtgataactcggagttgcctgggactttgcataattctcacaaaaagagaagaaacatttctgatctaaatcatcctcataaaaaacaaagaaaggaaacagacttaactaataaggaaaagaccaagaaacctacccaagattcttgtgagaatactgaagctcaccaaaagaaagccagtaagaagaaggcccctcctgtgactaaagatccctcatcattaaaggcaaccccagggattaaggattcatcagcagcacttgccacttctacaagtctttctgcaaaaaatgttattaaaaagaagggagaaattatcattttatggacaagaaatgatgaccgggaaattttattggagtgtcagaaaagagggccatcatttaaaacatttgcatatttagccgccaagttggataaaaatccaaatcaggtctcagaaagattccagcagctaatgaagctctttgaaaagtcaaaatgcagataagttgctgaattcctgggactcttaactgatattgcatactacacagaagcttcaaattcctcatgttttaaatgagcactagagggaggtttatcacctttttggttaccagatgataatctatatttgttattactcagtgactctctaatttcacatcagcatgttcagcttgtgctagtcatcattctgatttgcttatctgtttttggtcaaaatatttatttttaaacatgttagaacttaccaaaatgaaagcaacagtgatgtattgaaatcttagttttgatattttaaagaaatgactttctagattaaaaaaatagttttgtagcattttaaacttagtgactatttagttcaattgttcatccattttttatttgcttttataattgcctccttgttttggtatattgtaaaataatttaaataatgtatttataaatatgtataattatgatgtaaaataccgtgtgtatatgtatgtatgtgtgtttctgtatatgcacacacataaacggctttgcctagccaaggattttttttatctgtataaaactttttgtataaagtttgctttcaataacagtaatgtataataaaaccatgtaaagttttgttgtaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9994 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA
GeneID:9994 -> Molecular function: GO:0003714 [transcription corepressor activity] evidence: IDA
GeneID:9994 -> Molecular function: GO:0005123 [death receptor binding] evidence: TAS
GeneID:9994 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:9994 -> Molecular function: GO:0008656 [cysteine-type endopeptidase activator activity involved in apoptotic process] evidence: ISS
GeneID:9994 -> Molecular function: GO:0016505 [peptidase activator activity involved in apoptotic process] evidence: ISS
GeneID:9994 -> Molecular function: GO:0032184 [SUMO polymer binding] evidence: IDA
GeneID:9994 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:9994 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA
GeneID:9994 -> Biological process: GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] evidence: IMP
GeneID:9994 -> Biological process: GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] evidence: ISS
GeneID:9994 -> Biological process: GO:0007049 [cell cycle] evidence: IEA
GeneID:9994 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
GeneID:9994 -> Biological process: GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] evidence: IMP
GeneID:9994 -> Biological process: GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] evidence: ISS
GeneID:9994 -> Biological process: GO:0036337 [Fas signaling pathway] evidence: IMP
GeneID:9994 -> Biological process: GO:0071260 [cellular response to mechanical stimulus] evidence: IEP
GeneID:9994 -> Biological process: GO:0097190 [apoptotic signaling pathway] evidence: TAS
GeneID:9994 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:9994 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:9994 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
GeneID:9994 -> Cellular component: GO:0016605 [PML body] evidence: IDA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.