2025-05-09 17:21:57, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001127384 3174 bp mRNA linear PRI 24-JUN-2013 DEFINITION Homo sapiens catenin (cadherin-associated protein), alpha 3 (CTNNA3), transcript variant 2, mRNA. ACCESSION NM_001127384 VERSION NM_001127384.1 GI:188497717 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 3174) AUTHORS Borglum,A.D., Demontis,D., Grove,J., Pallesen,J., Hollegaard,M.V., Pedersen,C.B., Hedemand,A., Mattheisen,M., Uitterlinden,A., Nyegaard,M., Orntoft,T., Wiuf,C., Didriksen,M., Nordentoft,M., Nothen,M.M., Rietschel,M., Ophoff,R.A., Cichon,S., Yolken,R.H., Hougaard,D.M., Mortensen,P.B. and Mors,O. CONSRTM GROUP investigators TITLE Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci JOURNAL Mol. Psychiatry (2013) In press PUBMED 23358160 REMARK Publication Status: Available-Online prior to print REFERENCE 2 (bases 1 to 3174) AUTHORS van Hengel,J., Calore,M., Bauce,B., Dazzo,E., Mazzotti,E., De Bortoli,M., Lorenzon,A., Li Mura,I.E., Beffagna,G., Rigato,I., Vleeschouwers,M., Tyberghein,K., Hulpiau,P., van Hamme,E., Zaglia,T., Corrado,D., Basso,C., Thiene,G., Daliento,L., Nava,A., van Roy,F. and Rampazzo,A. TITLE Mutations in the area composita protein alphaT-catenin are associated with arrhythmogenic right ventricular cardiomyopathy JOURNAL Eur. Heart J. 34 (3), 201-210 (2013) PUBMED 23136403 REMARK GeneRIF: Results suggest a causal relationship between CTNNA3 mutations and arrhythmogenic right ventricular cardiomyopathy REFERENCE 3 (bases 1 to 3174) AUTHORS Shaffer,J.R., Feingold,E., Wang,X., Lee,M., Tcuenco,K., Weeks,D.E., Weyant,R.J., Crout,R., McNeil,D.W. and Marazita,M.L. TITLE GWAS of dental caries patterns in the permanent dentition JOURNAL J. Dent. Res. 92 (1), 38-44 (2013) PUBMED 23064961 REFERENCE 4 (bases 1 to 3174) AUTHORS Bernstein,D.I., Kashon,M., Lummus,Z.L., Johnson,V.J., Fluharty,K., Gautrin,D., Malo,J.L., Cartier,A., Boulet,L.P., Sastre,J., Quirce,S., Germolec,D., Tarlo,S.M., Cruz,M.J., Munoz,X., Luster,M.I. and Yucesoy,B. TITLE CTNNA3 (alpha-catenin) gene variants are associated with diisocyanate asthma: a replication study in a Caucasian worker population JOURNAL Toxicol. Sci. 131 (1), 242-246 (2013) PUBMED 22977168 REMARK GeneRIF: GWAS study of diisocyanate asthma demonstrates an association between two closely linked CTNNA3 gene SNPs and diisocyanate asthma. REFERENCE 5 (bases 1 to 3174) AUTHORS Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K., Gibbs,R.A. and Butte,N.F. TITLE Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population JOURNAL PLoS ONE 7 (12), E51954 (2012) PUBMED 23251661 REFERENCE 6 (bases 1 to 3174) AUTHORS Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M., French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S., Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G., Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P., Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D., Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K., Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P., Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N., Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A., Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C., Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E., Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E., Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M., Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M., Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J., Lovell,J., McLaren,S., McLay,K.E., McMurray,A., Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T., Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A., Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D., Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A., Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J., Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L., Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C., Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R., Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J. TITLE The DNA sequence and comparative analysis of human chromosome 10 JOURNAL Nature 429 (6990), 375-381 (2004) PUBMED 15164054 REFERENCE 7 (bases 1 to 3174) AUTHORS Busby,V., Goossens,S., Nowotny,P., Hamilton,G., Smemo,S., Harold,D., Turic,D., Jehu,L., Myers,A., Womick,M., Woo,D., Compton,D., Doil,L.M., Tacey,K.M., Lau,K.F., Al-Saraj,S., Killick,R., Pickering-Brown,S., Moore,P., Hollingworth,P., Archer,N., Foy,C., Walter,S., Lendon,C., Iwatsubo,T., Morris,J.C., Norton,J., Mann,D., Janssens,B., Hardy,J., O'Donovan,M., Jones,L., Williams,J., Holmans,P., Owen,M.J., Grupe,A., Powell,J., van Hengel,J., Goate,A., Van Roy,F. and Lovestone,S. TITLE Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease JOURNAL Neuromolecular Med. 5 (2), 133-146 (2004) PUBMED 15075440 REMARK GeneRIF: We found no association between CTNNA3 and Alzheimer disease in subjects showing linkage to chromosome 10, nor were these SNPs associated with Abeta deposition in brain. CTNNA3 is unlikely to account for the susceptibility locus on chromosome 10 REFERENCE 8 (bases 1 to 3174) AUTHORS Ertekin-Taner,N., Ronald,J., Asahara,H., Younkin,L., Hella,M., Jain,S., Gnida,E., Younkin,S., Fadale,D., Ohyagi,Y., Singleton,A., Scanlin,L., de Andrade,M., Petersen,R., Graff-Radford,N., Hutton,M. and Younkin,S. TITLE Fine mapping of the alpha-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees JOURNAL Hum. Mol. Genet. 12 (23), 3133-3143 (2003) PUBMED 14559775 REMARK GeneRIF: Alpha-T catenin gene has variants which influence Abeta42 and contribute to the previously reported linkage for plasma Abeta42 in late-onset Alzheimer's disease families. REFERENCE 9 (bases 1 to 3174) AUTHORS Janssens,B., Mohapatra,B., Vatta,M., Goossens,S., Vanpoucke,G., Kools,P., Montoye,T., van Hengel,J., Bowles,N.E., van Roy,F. and Towbin,J.A. TITLE Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy JOURNAL Hum. Genet. 112 (3), 227-236 (2003) PUBMED 12596047 REMARK GeneRIF: gene localized on chromosome 10q21 and is 1,776 kb in length; mutation screening of all 18 exons of the CTNNA3 gene in a family showing dilated cardiomyopathy (DCM)linkage to the 10q21-q23 locus, however, has not detected any DCM-linked CTNNA3 mutations REFERENCE 10 (bases 1 to 3174) AUTHORS Janssens,B., Goossens,S., Staes,K., Gilbert,B., van Hengel,J., Colpaert,C., Bruyneel,E., Mareel,M. and van Roy,F. TITLE alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion JOURNAL J. Cell. Sci. 114 (PT 17), 3177-3188 (2001) PUBMED 11590244 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP362015.1, AK289756.1 and AF091606.1. Transcript Variant: This variant (2) utilizes an alternate first exon resulting in a distinct 5'UTR. Transcript variants 1 and 2 encode the same protein isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289756.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025082, ERS025083 [ECO:0000350] ##Evidence-Data-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-37 BP362015.1 1-37 38-1909 AK289756.1 1-1872 1910-2968 AF091606.1 1962-3020 2969-3174 AK289756.1 2932-3137 FEATURES Location/Qualifiers source 1..3174 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="10" /map="10q22.2" gene 1..3174 /gene="CTNNA3" /gene_synonym="VR22" /note="catenin (cadherin-associated protein), alpha 3" /db_xref="GeneID:29119" /db_xref="HGNC:2511" /db_xref="MIM:607667" exon 1..118 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(32) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:374617915" exon 119..222 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" CDS 124..2811 /gene="CTNNA3" /gene_synonym="VR22" /note="alpha-catenin-like protein; alpha-T-catenin; alpha T-catenin; cadherin-associated protein" /codon_start=1 /product="catenin alpha-3" /protein_id="NP_001120856.1" /db_xref="GI:188497718" /db_xref="CCDS:CCDS7269.1" /db_xref="GeneID:29119" /db_xref="HGNC:2511" /db_xref="MIM:607667" /translation="
MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAGPRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFRGRQIY
" misc_feature 175..2691 /gene="CTNNA3" /gene_synonym="VR22" /note="Vinculin family; Region: Vinculin; pfam01044" /db_xref="CDD:110072" misc_feature 2032..2034 /gene="CTNNA3" /gene_synonym="VR22" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (Q9UI47.2); phosphorylation site" variation complement(141) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:138580439" variation complement(156) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:61735044" variation complement(183) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:374611639" variation complement(196) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:375607074" exon 223..415 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(275) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:143725018" variation complement(278) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:139105272" variation complement(279) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:61759502" variation complement(283) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:200409596" variation complement(284) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:377158111" variation complement(288) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:141527898" variation complement(309) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:369638097" variation complement(312) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:375304070" variation complement(334) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:10997754" variation complement(337) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:371997421" variation complement(341) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:141436901" variation complement(355) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:201306690" exon 416..582 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(435) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:201480758" variation complement(471) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:61749224" variation complement(499) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:373661106" variation complement(510) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:143943926" variation complement(516) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:80182543" variation complement(522) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:150376558" variation complement(552) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:111880127" variation complement(571) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:368622093" variation complement(580) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:147116577" exon 583..702 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(583) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:374067925" variation complement(601) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:61749223" variation complement(606) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:74142830" variation complement(701) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:373233387" exon 703..966 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(725) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:372957321" variation complement(728) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:138821753" variation complement(746) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:369420715" variation complement(759) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:200809148" variation complement(767) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:146441824" variation complement(772) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:374834298" variation complement(777) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:371330302" variation complement(841) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:367570454" variation complement(865) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:192093851" variation complement(869) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:146048212" variation complement(872) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:372717475" variation complement(883) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:368470427" variation complement(891) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:140926333" variation complement(902) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:190073606" variation complement(917) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:151069922" variation complement(919) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:199985402" variation complement(931) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:368027975" variation complement(942) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:146622691" variation complement(955) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:143693772" exon 967..1170 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(989) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:375250429" variation complement(990) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:149090594" variation complement(993) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:369449859" variation complement(1003) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:146475470" variation complement(1013) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:201596778" variation complement(1053) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:144152750" variation complement(1068) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:375992799" variation complement(1082) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:139460414" variation complement(1090) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:113836576" variation complement(1096) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:369024617" variation complement(1105) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:374713975" variation complement(1109) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:181929603" variation complement(1110) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:372427902" variation complement(1122) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:146754105" variation complement(1126) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:370088870" variation complement(1129) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:375721994" variation complement(1130) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:372482202" variation complement(1158) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:368211074" variation complement(1159) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:143203517" variation complement(1170) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:60262757" exon 1171..1251 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(1178) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:141978685" variation complement(1187) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:375610128" variation complement(1220) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:201966934" variation complement(1243) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:370981751" exon 1252..1404 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(1255) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:187752783" variation complement(1256) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:143682596" variation complement(1277) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:149348606" variation complement(1298) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:146777494" variation complement(1299) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:138898184" variation complement(1309) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:376091500" variation complement(1315) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:145043626" variation complement(1318) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:115276158" variation complement(1321) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:374015031" variation complement(1322) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:201896157" variation complement(1342) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:138643733" variation complement(1343) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:369880246" variation complement(1354) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:372808360" variation complement(1359) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:150167695" variation complement(1386) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:140907744" variation complement(1401) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:143981286" exon 1405..1497 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(1426) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:377404952" variation complement(1427) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:369650832" exon 1498..1654 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(1513) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:367599520" variation complement(1525) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:151007312" variation complement(1544) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:201810511" variation complement(1545) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:372258059" variation complement(1569) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:76737066" variation complement(1571) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:200282168" variation complement(1573) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:200182913" variation complement(1576) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:140913916" variation complement(1595) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:201173778" variation complement(1599) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:182681928" variation complement(1612) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:368067642" variation complement(1614) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:141098613" variation complement(1630) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:147802834" variation complement(1632) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:375080368" exon 1655..1855 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(1662) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:377413642" variation complement(1672) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:373151978" variation complement(1681) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:144269113" variation complement(1697) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:369650158" variation complement(1710) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:74141466" variation complement(1711) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:74141465" variation complement(1726) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:41274090" variation complement(1727) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:139378888" variation complement(1734) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:146900023" variation complement(1750) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:372758887" variation complement(1751) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:369033938" variation complement(1753) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:376250417" variation complement(1763) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:374703865" variation complement(1778) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:61737718" variation complement(1780) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:371983729" variation complement(1796) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:141429762" variation complement(1798) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:367823042" variation complement(1805) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:374844431" variation complement(1812) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:370247825" variation complement(1815) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:138798862" variation complement(1823) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:146096912" variation complement(1826) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:376984969" variation complement(1844) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:375428912" variation complement(1846) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:199940048" exon 1856..2007 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(1858) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:375734372" variation complement(1862) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:368000502" variation complement(1910) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:4548513" variation complement(1915) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:187527391" variation complement(1923) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:137910578" variation complement(1936) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:139661235" variation complement(1946) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:138314889" variation complement(1971) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:182490263" variation complement(1973) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:190239785" variation complement(1976) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:184992188" variation complement(1988) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:367616357" variation complement(1995) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:10997034" variation complement(2005) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:149081490" exon 2008..2100 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(2023) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:77165728" variation complement(2050) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:141141746" variation complement(2052) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:147760277" variation complement(2056) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:370600208" variation complement(2059) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:111425421" variation complement(2060) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:370269225" variation complement(2062) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:376927818" variation complement(2091) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:200764970" exon 2101..2282 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(2129) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:377166040" variation complement(2164) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:142116698" variation complement(2176) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:199697536" variation complement(2189) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:150734357" variation complement(2194) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:374172412" variation complement(2220) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:142942346" variation complement(2245) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:148554495" variation complement(2265) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:115972723" variation complement(2281) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:143867269" exon 2283..2388 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(2295) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:116662854" variation complement(2334) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:192848934" variation complement(2364) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:113397208" variation complement(2371) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /replace="t" /db_xref="dbSNP:149211186" variation complement(2372) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:367848292" variation complement(2383) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:142752710" exon 2389..2523 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(2392) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:373175781" variation complement(2394) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:372746141" variation complement(2406) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:372435356" variation complement(2425) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:368637046" variation complement(2445) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:374450104" variation complement(2501) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:188248522" variation complement(2503) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:145119798" exon 2524..3174 /gene="CTNNA3" /gene_synonym="VR22" /inference="alignment:Splign:1.39.8" variation complement(2533) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:370688983" variation complement(2537) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:200392000" STS 2582..3088 /gene="CTNNA3" /gene_synonym="VR22" /standard_name="CTNNA3_4652" /db_xref="UniSTS:462847" variation complement(2617) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="t" /db_xref="dbSNP:376310020" variation complement(2623) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:202196166" variation complement(2624) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:373081692" variation complement(2647) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:199852825" variation complement(2673) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:138237676" variation complement(2676) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:115814032" variation complement(2696) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="t" /db_xref="dbSNP:41313840" variation complement(2751) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:377740786" variation complement(2752) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:374368635" variation complement(2779) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:376134614" variation complement(2819) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:190581449" variation complement(2826) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="c" /db_xref="dbSNP:369681914" variation complement(2910) /gene="CTNNA3" /gene_synonym="VR22" /replace="c" /replace="g" /db_xref="dbSNP:371283856" variation complement(3054) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:77424782" variation complement(3066) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:185258162" variation complement(3073) /gene="CTNNA3" /gene_synonym="VR22" /replace="a" /replace="g" /db_xref="dbSNP:74442277" variation complement(3119) /gene="CTNNA3" /gene_synonym="VR22" /replace="g" /replace="t" /db_xref="dbSNP:192926725" ORIGIN
agatgcatcataagccaaattgtgagccatgatagtggcactgaatttctaaatacaagaaattgcttagacaattggtttagtatctgtatatgggcaatactctgtcctgcagtaggcagcatgtcagctgaaacaccaatcacattgaatatcgatcctcaggatctgcaggtccaaacattcaccgtggagaagctactggagcctctcataatccaggttaccacacttgtaaactgtccccagaacccttccagcaggaaaaaaggacgttcgaaaagagccagtgtccttctagcttctgtggaggaagcaacttggaatttattagacaagggagagaagattgcccaggaagctacagttttaaaggatgagcttacggcttcacttgaggaagttcgcaaagaaagtgaagctctgaaagtatcagctgagagatttacagatgacccctgttttctcccaaaaagggaggctgtggttcaagctgcccgtgccttgctggctgcggtgacgagactccttatccttgcggacatgattgatgtcatgtgcctcttgcaacatgtgtcagcttttcaaaggacatttgagtctctcaaaaatgttgccaacaaatctgacctccagaaaacctaccagaagcttgggaaggagctggaaaatttggattatttagccttcaaacgtcagcaggacttaaaatctccaaatcagagagatgaaattgcaggagcccgagcttcactgaaggagaactctcccctcttgcattcaatttgttcagcttgtttggagcattctgatgttgcttccctcaaagcaagcaaggacacagtttgtgaagaaattcagaatgctctcaatgtaatttcaaatgcttcacaagggatccagaatatgacaaccccaccagaacctcaggcagcaaccctgggaagtgcccttgatgagctggagaatttaattgtcctgaatccactcacagtaactgaggaggaaatacgaccatcactagagaaacgccttgaagccattatcagtggggctgctctgctggcggattcttcatgtacgagggacttacaccgagagcggattatcgcagaatgcaacgccattcgccaggctcttcaggatctgctttcagagtacatgaacaacgctggaaaaaaagaaaggagtaataccctgaatattgctttagacaacatgtgtaagaagacaagagaccttcgcagacagctccgcaaggctattatagatcatgtgtcagactctttcctggatacgacagtccctcttttggttctcattgaagctgctaagaatggccgggaaaaggaaataaaagaatatgctgcgatatttcatgaacacaccagcaggcttgtagaggtggcaaatcttgcttgttccatgtcaacaaatgaagatggaattaaaattgtcaaaattgcagccaatcatttggaaaccttgtgtccacagattattaatgctgcacttgctttggctgcaagacccaaaagtcaagcggtcaaaaacaccatggaaatgtacaagcgtacatgggagaatcatatacatgtcctcactgaagccgtagatgacattacaagcattgatgacttccttgctgtatctgaaagccatatcttggaagatgtcaacaagtgtatcatagccttaagagaccaggatgctgataatttagaccgtgctgcgggtgctatcagaggccgggcagcaagagttgctcacatcgtcacgggtgaaatggacagttacgagccaggggcttacacggaaggtgtaatgagaaatgttaacttccttacaagtactgtaattcctgaatttgtaacacaagtgaatgttgccttggaagccttaagcaaaagctcattgaatgtgttggatgataatcaatttgtggacatctcaaagaagatctatgatacaattcatgatatcagatgttcagtcatgatgattcggaccccagaggaactggaggatgtttctgaccttgaagaggaacacgaggtccgcagtcacaccagcattcagaccgaagggaaaactgatagggctaagatgactcaactgcctgaggcagaaaaagaaaagattgctgagcaagttgctgatttcaagaaagtaaagagtaagctggatgctgagattgagatatgggatgatacaagcaacgacatcattgttctggccaagaacatgtgtatgatcatgatggagatgacagacttcactaggggcaaaggaccactaaagcatacaactgatgtgatctatgcagcgaaaatgatatcagaatcaggatcaaggatggatgtccttgctcggcagattgctaatcagtgcccagatccatcttgtaaacaggacttgttggcctacctggaacagattaagttctactcccaccaactgaaaatctgcagtcaagttaaagctgagatccagaacctgggaggagagctcatcatgtcagctttggacagtgtcacatccctgatccaagcagccaaaaatttaatgaatgctgtagtgcaaacagtgaaaatgtcttacattgcctcaaccaagatcatccgaatccagagtcctgctgggccccggcacccagttgtgatgtggagaatgaaggctcctgcaaaaaaacccttgattaaaagagagaagccagaggaaacgtgtgcagctgtcagacgaggctcagcaaagaaaaaaatccatccattgcaagtcatgagtgaatttagaggaagacaaatctactgaaaccactattctacatatagtgcctatatgacaaaatcctgcctaaccacactgctttattttacacttaagaagttctgtaatttcactaagttttggtgtttaactcacaaataacataaaatattgggcgctaaatcaacaaaagcaatatatatttgggatcatatcactgtcatttctgtatggtcagcacctaatagttaaggaatatttgcttgttgaatgaatgaaattatcacgtgtcattcagcgtttcccatcatagagattatctactattcgttaccaaataaacacaggagaggccagagagtcctgtttatctgtaatacttcatgtacacttatcatccttatcttg
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:29119 -> Molecular function: GO:0005198 [structural molecule activity] evidence: IEA GeneID:29119 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:29119 -> Molecular function: GO:0045296 [cadherin binding] evidence: TAS GeneID:29119 -> Biological process: GO:0016337 [cell-cell adhesion] evidence: IPI GeneID:29119 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA GeneID:29119 -> Cellular component: GO:0005916 [fascia adherens] evidence: IDA GeneID:29119 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: IEA GeneID:29119 -> Cellular component: GO:0030027 [lamellipodium] evidence: IEA
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