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2025-05-09 16:47:07, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001037954 5963 bp mRNA linear PRI 21-JUN-2013
DEFINITION Homo sapiens DIX domain containing 1 (DIXDC1), transcript variant
1, mRNA.
ACCESSION NM_001037954
VERSION NM_001037954.3 GI:513126886
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5963)
AUTHORS Liu,Y.T., Dan,Q.J., Wang,J., Feng,Y., Chen,L., Liang,J., Li,Q.,
Lin,S.C., Wang,Z.X. and Wu,J.W.
TITLE Molecular basis of Wnt activation via the DIX domain protein Ccd1
JOURNAL J. Biol. Chem. 286 (10), 8597-8608 (2011)
PUBMED 21189423
REMARK GeneRIF: a molecular mechanism for Ccd1-mediated Wnt activation in
that Ccd1 converts latent polymeric Dvl to a biologically active
oligomer(s).
REFERENCE 2 (bases 1 to 5963)
AUTHORS Kivimae,S., Martin,P.M., Kapfhamer,D., Ruan,Y., Heberlein,U.,
Rubenstein,J.L. and Cheyette,B.N.
TITLE Abnormal behavior in mice mutant for the Disc1 binding partner,
Dixdc1
JOURNAL Transl Psychiatry 1, E43 (2011)
PUBMED 22832659
REMARK GeneRIF: Transgenic DIXDC1 might contribute to pathophysiology
underlying abnormal behaviors in schizophrenia and other major
psychiatric disorders in mice.
Publication Status: Online-Only
REFERENCE 3 (bases 1 to 5963)
AUTHORS Singh,K.K., Ge,X., Mao,Y., Drane,L., Meletis,K., Samuels,B.A. and
Tsai,L.H.
TITLE Dixdc1 is a critical regulator of DISC1 and embryonic cortical
development
JOURNAL Neuron 67 (1), 33-48 (2010)
PUBMED 20624590
REMARK GeneRIF: This study reveal that Dixdc1 integrates DISC1 into
Wnt-GSK3beta/beta-catenin-dependent and -independent signaling
pathways during cortical development and further delineate how
DISC1 contributes to neuropsychiatric disorders.
REFERENCE 4 (bases 1 to 5963)
AUTHORS Wang,L., Li,H., Chen,Q., Zhu,T., Zhu,H. and Zheng,L.
TITLE Wnt signaling stabilizes the DIXDC1 protein through decreased
ubiquitin-dependent degradation
JOURNAL Cancer Sci. 101 (3), 700-706 (2010)
PUBMED 20085589
REMARK GeneRIF: Wnt/beta-catenin pathway activation might upregulate
DIXDC1 through a post-translational mechanism by inhibiting the
ubiquitin-mediated degradation of the DIXDC1 protein.
REFERENCE 5 (bases 1 to 5963)
AUTHORS Liu,T., Wang,L., Chen,Q., Zheng,L. and Zhu,H.
TITLE A novel monoclonal antibody specific to DIXDC1 protein
JOURNAL Hybridoma (Larchmt) 28 (3), 183-188 (2009)
PUBMED 19519246
REFERENCE 6 (bases 1 to 5963)
AUTHORS Wu,Y., Jing,X., Ma,X., Wu,Y., Ding,X., Fan,W. and Fan,M.
TITLE DIXDC1 co-localizes and interacts with gamma-tubulin in HEK293
cells
JOURNAL Cell Biol. Int. 33 (6), 697-701 (2009)
PUBMED 19375513
REMARK GeneRIF: The GFP-tag fused DIXDC1 exogenously expressed co-localize
with gamma-tubulin both at interphase and mitotic phase in the
centrosomes.
REFERENCE 7 (bases 1 to 5963)
AUTHORS Jing,X.T., Wu,H.T., Wu,Y., Ma,X., Liu,S.H., Wu,Y.R., Ding,X.F.,
Peng,X.Z., Qiang,B.Q., Yuan,J.G., Fan,W.H. and Fan,M.
TITLE DIXDC1 promotes retinoic acid-induced neuronal differentiation and
inhibits gliogenesis in P19 cells
JOURNAL Cell. Mol. Neurobiol. 29 (1), 55-67 (2009)
PUBMED 18629627
REMARK GeneRIF: DIXDC1 might play an important role during neurogenesis,
overexpression of DIXDC1 in embryonic carcinoma P19 cells promoted
neuronal differentiation, and inhibited gliogenesis induced by
retinoic acid.
REFERENCE 8 (bases 1 to 5963)
AUTHORS Wang,X., Zheng,L., Zeng,Z., Zhou,G., Chien,J., Qian,C.,
Vasmatzis,G., Shridhar,V., Chen,L. and Liu,W.
TITLE DIXDC1 isoform, l-DIXDC1, is a novel filamentous actin-binding
protein
JOURNAL Biochem. Biophys. Res. Commun. 347 (1), 22-30 (2006)
PUBMED 16814745
REMARK GeneRIF: Thus, our data provide the first evidence that l-DIXDC1
may act as a novel branching component in the Wnt signaling pathway
targeting both beta-catenin-TCF complex for gene expression and
cytoskeleton for regulating dynamics of actin filaments.
REFERENCE 9 (bases 1 to 5963)
AUTHORS Wong,C.K., Luo,W., Deng,Y., Zou,H., Ye,Z. and Lin,S.C.
TITLE The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal
kinase activation by Axin and dishevelled through distinct
mechanisms
JOURNAL J. Biol. Chem. 279 (38), 39366-39373 (2004)
PUBMED 15262978
REMARK GeneRIF: Ccd1 inhibits Axin-mediated JNK activation by
simultaneously adopting two distinct mechanisms, one through
conformational changes that disallow MEKK1 binding and the other
via direct sequestration of MEKK4.
REFERENCE 10 (bases 1 to 5963)
AUTHORS Katoh,M. and Katoh,M.
TITLE KIAA1735 gene on human chromosome 11q23.1 encodes a novel protein
with myosine-tail homologous domain and C-terminal DIX domain
JOURNAL Int. J. Oncol. 23 (1), 145-150 (2003)
PUBMED 12792787
REMARK GeneRIF: KIAA1735 maps to human chromosome 11q23.1 and encodes a
novel protein with a myosine-tail homologous domain and C-terminal
DIX domain
GeneRIF: MTHDIX (KIAA1735) protein consists of Myosine-tail
homologous (MTH) domain and C-terminal DIX domain.
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DQ642016.1, BC064479.1,
AB051522.1, AB074187.1 and DB358954.1.
This sequence is a reference standard in the RefSeqGene project.
On Jun 19, 2013 this sequence version replaced gi:116256345.
Summary: The protein encoded by this gene is a positive regulator
of the Wnt signaling pathway. The encoded protein is found
associated with gamma tubulin at the centrosome. Alternative
splicing results in multiple transcript variants encoding different
isoforms. [provided by RefSeq, Jun 2013].
Transcript Variant: This variant (1) represents the longest
transcript and encodes the longest isoform (a, also known as
l-DIXDC1).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: DQ642016.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025083 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-184 DQ642016.1 1-184
185-1176 BC064479.1 1-992
1177-2159 DQ642016.1 1177-2159
2160-5292 AB051522.1 1600-4732
5293-5897 AB074187.1 1108-1712
5898-5963 DB358954.1 1-66 c
FEATURES Location/Qualifiers
source 1..5963
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q23.1"
gene 1..5963
/gene="DIXDC1"
/gene_synonym="CCD1"
/note="DIX domain containing 1"
/db_xref="GeneID:85458"
/db_xref="HGNC:23695"
/db_xref="MIM:610493"
exon 1..357
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
misc_feature 205..207
/gene="DIXDC1"
/gene_synonym="CCD1"
/note="upstream in-frame stop codon"
CDS 298..2349
/gene="DIXDC1"
/gene_synonym="CCD1"
/note="isoform a is encoded by transcript variant 1;
dixin; coiled-coil protein DIX1"
/codon_start=1
/product="dixin isoform a"
/protein_id="NP_001033043.1"
/db_xref="GI:83816971"
/db_xref="GeneID:85458"
/db_xref="HGNC:23695"
/db_xref="MIM:610493"
/translation="
MLACLTRGNLLDVLQEGFNEQQLQAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPGNQQEMKNNVEKVLQFVASKKIRMHQTSAKDIVDGNLKSIMRLVLALAAHFKPGSSRTVNQGRDSRAPLQSHRPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
"
misc_feature 361..675
/gene="DIXDC1"
/gene_synonym="CCD1"
/note="Calponin homology domain; actin-binding domain
which may be present as a single copy or in tandem repeats
(which increases binding affinity). The CH domain is found
in cytoskeletal and signal transduction proteins,
including actin-binding proteins like...; Region: CH;
cd00014"
/db_xref="CDD:28898"
misc_feature order(361..363,367..375,382..384,391..393,562..567,
574..576,583..585,589..591,634..639,646..651,655..660,
667..672)
/gene="DIXDC1"
/gene_synonym="CCD1"
/note="putative actin binding surface [polypeptide
binding]; other site"
/db_xref="CDD:28898"
misc_feature 676..1197
/gene="DIXDC1"
/gene_synonym="CCD1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q155Q3.2);
Region: Actin-binding"
misc_feature 2098..2337
/gene="DIXDC1"
/gene_synonym="CCD1"
/note="DIX domain; Region: DIX; pfam00778"
/db_xref="CDD:189714"
exon 358..487
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 488..613
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 614..845
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 846..953
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 954..1066
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1067..1215
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1216..1305
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1306..1359
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1360..1410
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1411..1515
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1516..1569
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1570..1662
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1663..1734
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1735..1824
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1825..1986
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 1987..2053
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 2054..2159
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 2160..2268
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
exon 2269..5963
/gene="DIXDC1"
/gene_synonym="CCD1"
/inference="alignment:Splign:1.39.8"
STS 3889..4136
/gene="DIXDC1"
/gene_synonym="CCD1"
/standard_name="STS-AA026898"
/db_xref="UniSTS:6593"
STS 4187..4339
/gene="DIXDC1"
/gene_synonym="CCD1"
/standard_name="RH103217"
/db_xref="UniSTS:97550"
STS 4472..5340
/gene="DIXDC1"
/gene_synonym="CCD1"
/standard_name="DIXDC1__4742"
/db_xref="UniSTS:462869"
STS 5142..5219
/gene="DIXDC1"
/gene_synonym="CCD1"
/standard_name="RH36905"
/db_xref="UniSTS:87932"
STS 5695..5846
/gene="DIXDC1"
/gene_synonym="CCD1"
/standard_name="RH104183"
/db_xref="UniSTS:98508"
polyA_signal 5873..5878
/gene="DIXDC1"
/gene_synonym="CCD1"
polyA_site 5896
/gene="DIXDC1"
/gene_synonym="CCD1"
/note="The 3' most polyA site has not been determined."
ORIGIN
tcccgcaggaaagcggggctgggggcagcccggcagcgccgctcaacctagtgcgcgcccagttgtttccataggaaccgcgaccgcgccgggcccctccagcggaggcccccgtgcgagcatgcccagtgcaagccgctagtttggctccagtctaggtttccagtaagtggcatgcgggactccggagggatcccaatgagctgagccgagagcctttgtgtgcagagggaggaggaggaggcggcggcggccgccgggctggagaccccgcccggggagcccccagcaggaacaatgctagcctgcctgacccgagggaacttactggacgtcctgcaggagggcttcaatgagcaacagctgcaggcctatgtggcctgggtgaatgcacagctgaagaagaggccagcagtgaagcctgtgcaggacctgcgacaagatctccgggatggggtgatcctggcatatctcatcgagattgttgcaggagaaaagctgagtggggtacagctgagtcccggtaaccaacaggagatgaagaataatgtggagaaagtgctacagtttgtggcctctaaaaagattcgtatgcaccagacttcggctaaagatattgtggatggaaacctgaagtctatcatgaggctggtccttgccttggcagctcatttcaaacctggctccagcaggacggtgaaccaaggacgggactccagagcccctctgcaaagtcaccgaccacactgtgccactgctgttgcccagggagcagctgctgctctggccgatgtgtgtcatgacatgtcccgatcaggacgggatgtctttcgatatagacagaggaacagcagcatggatgaggaaattgagaatccatactggagtgtgcgggccctagtgcagcagtacgaagggcaacaaaggtccccgtctgaatccagctgctccagcctgacttcacccagtccaatccacagtgcaaagagcgagtccattataacccagtcagaagagaaggcagattttgtgattattcccgctgaaggaatagagaacagaacagaagggacagattctccattatctcgagactggcggccagggagccctggaacctatctggagacctcatgggaagaacagctgttggaacaacaagaatatttagaaaaagaaatggaggaagcaaagaaaatgatatcaggactacaggccttactgctcaatggatccttacctgaagatgaacaggagaggcccttggccctctgtgaaccaggtgtcaatcccgaggaacaactgattataatccaaagtcgtctggatcagagtatggaggagaatcaggacttaaagaaggaactgctgaaatgtaaacaagaagccagaaacttacaggggataaaggatgccttgcagcagagattgactcagcaggacacatctgttcttcagctcaaacaagagctactgagggcaaatatggacaaagatgagctgcacaaccagaatgtggatctgcagaggaagctagatgagaggaaccggctcttgggagaatataaaaaagagctggggcagaaggatcgccttcttcagcagcaccaggccaagttagaagaagcactccggaaactctctgatgtcagttaccaccaggtggatctagagcgagagctagaacacaaagatgtcctcttggctcactgtatgaaaagagaggcagatgaggcgaccaactacaacagtcacaactctcaaagcaatggttttctccttccaacggcaggaaaaggagctacttcagtcagcaacagagggaccagcgacctgcagcttgttcgagatgctctccgcagcctgcgcaacagcttcagtggccacgatcctcagcaccacactattgacagcttggagcagggcatttctagcctcatggagcgcctgcatgttatggagacgcagaagaaacaagaaagaaaggttcgggtcaagtcacccagaactcaagtaggtagtgaataccgggagtcctggccccctaactcaaagttgcctcactcacagagctctccaactgtcagcagcacctgtactaaagtgctctatttcactgaccggtcacttacgcccttcatggtcaatataccaaagaggttggaggaggtgacgttaaaggattttaaagcagctattgatcgggaaggaaatcaccggtatcacttcaaagcactggatcctgagtttggcactgtcaaagaggagattttccatgatgatgatgccatccctggatgggaagggaaaattgtagcttgggtggaagaagaccatggagagaattaatgccaagtatcagattgagggcttatggaacctggtcactccctggctgcttcactcaggaaagggaactaaaaccagaatacactaagaagtttctagtttgtgtgccaaaacagaagcttctccaagcatgatggccacaggtcagtcctctttctgtgcctggcatatctggtacttaaaattctgtccaaatgtagaccatgggttcatctggagttccttgtccgtgggaacacagtgttctattctactctgaggacaacaaaccgaaggccttaaacgatggggatggatgatcccgcctctgtaggggcatggctgctattatctggaaattaggaattggatgcatcattcctgtgtgttacagtattattttaattggcctcaatggttgcagcaatcagagtcccagcgtttgtactcacagacaaggcaaaggtaccagcttttctgtttctttgaacctactgcaaaccaagaataactcatgaggtggtaccaaagatgaaagcccagacttcagtaatcttttgaaccagacgtggatggtgctgaattgttgcttggatggaaaaagggctgcccatgttgtgctacactatgctaaaactgtaatttagtaagaccttgggctgcctcttctgtcttaactggttctgcagcttgtccttttgcccacatagggcctatttcatgtactgttagttttctctggggactctttaactttagagccatttctttttcttcaaactgatgaacttttgtttgaaaggcataaggagtgaaaagctccttgaaaatccaggcgggtatggaaaggtgctgctacccatatctttttgactttctttgtttcatgactttaactcatggcatctcctttgtagtaaaaggagacagaccattaatttcagcatttctttgtgatttataagtactgagcatgaagtacttgtctgcccctcatttcaaggccagagttattttctatttatgtattagtctaggctgatcttttagggcacaatagaaaccatggggcgtggagcatgagttgtgaatggcagggatcattctgggtaaaaaaaacctagaatcatttctgatgtgcaacattgtcaagtgaagaagctaacagttcaactaccgagattatttgataacctgggttttctcattcatccatcaagcaccatcaaccagtcagccattattatttatatatgtattaccaaaagcagtctatctgcctgtgacctccaatgtacactgccaaacacaagagtaggacacatctgttctgggttcttgacctatctgtctccaattcatctccccttttcagccatttcaacaaactactctttggagctctgagatgacatcttgttgttttatatagatgtatcttttaaaaatagttcacgtttggagaattcttttgtactcatttgctttttgtctgagaaccatgtctatttttataactggagtgtgagttctgtatcttctcacattctgtatactgtatccattttctagagaacccagtagcttttatacagtctcttcttaccaccccttgtggtttcagaacaagctttattttattacgagtatattaatgacaactaattcctgttccaattctacctgttttagttgtgaaggtagttttgtgtaatccagttgattgctcctctggcagagagaaggagctcaaaagatacttgatgtctttcatgtaagtttacctggtcttttcctattgaagaatttttcatcagaaacgactgggaaagtttgggaaagtcagcaaaagaaagaatgcatttcgaaagcaaacagaagaaaaaagtatattctcacagtttttccccaggaagtctggagaaaaagtcctcatgtcaccaatttctctgttgcatgaattttagtgttttgctataagacagcatgagggctatcaggccaaaattcattattgtatttccaatacagtttgtcttgaatgtctgtctcttaaaccagtttttacttgtcagttttctctcagcaaacagtcttactattatgtggaatttaacttttcagagaaaatttccaaagtcctctaccttatttggcttttatctgtgtcttttggaaaaggagctgcatggcctcagtgcctccataaaaagcttaagttgagttcatgggagaacattaagatcgttttttttcccttttagctcggtaatctcatgtaccacaggtaatgaccaagcatctctgctagaggatgtaactctcataactcctgtgtaaaatgaggatcctgttggtgatcctcattccagtttccaaagcgagaggagccttctgagcagaagtatgcaagactgattctgtttggaacagtttcctatttggctgcattctaggaggcctcctgacttattcatagtattgtcgcctggtggcattggtgtggggtagcttgtcctgctacttgctaaagttctctttctttgagaaaactgaggaaccagaatgcttagagttcataaaataatctctaaaccatgttaggttaaaacaaaatgaccatctcacaaaaacgagtttagttgaatgctcaattccttacaaaatcttcatttaaggctgagtgtggtggctcatgcctgtaattccagcactttgggaggccgaggcaggaagactgcttgagcccaggagttcaagaccagcctgggcaacgtaggaagactccgtctctacatagaaattttattataaaagtagctggggatggtggcacacacctgtagtcccagctactcaggaggttgaggtgggaagattgcttgagcccaggagtttgaggttgcagtgagctgatcatgccactgcactctagcctaggctacagagcaggaccccatctccaaaaaaaaaaaaaaaaaagtcatttaaaaactgaagaatgttctcttcttgctcagttccctaaattagctggggggattgggatactttacaatttttacatttttaaatttgaagaatttgttttaaacttacttggtaatggcacttctacttactgaccaacttttcagctctttttgaccaggatggttgcaaattagggaaaatatctttatactatacatccaattcaagaggactttaattacttaaaagcatttaggtcataattaaaattattttcactgtttccataaaataagcattatgattgcacactccttctactgtctgaatttatgtaagaggtatagcttgcttaaaatacatatatatgtaaagttatattttcttagaaacatggatgtttacagccattgctttcaaagagattattactgtgtattctccctgttttacaatatgttttcatgaagactatgttacaccagaggcttctgattatcaaagtgataaccagttttaactgccggtatgtaccagatttgtgaactaatttaaaaaaccacaaactatgaataaaatggggtttgcaaactaaatatcattaatgattttcacttgcgtttactgatgagattaatcaataaagccatttacatttagtg
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:85458 -> Molecular function: GO:0003779 [actin binding] evidence: IEA
GeneID:85458 -> Molecular function: GO:0004871 [signal transducer activity] evidence: IEA
GeneID:85458 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:85458 -> Molecular function: GO:0031435 [mitogen-activated protein kinase kinase kinase binding] evidence: IBA
GeneID:85458 -> Molecular function: GO:0043015 [gamma-tubulin binding] evidence: IDA
GeneID:85458 -> Biological process: GO:0021695 [cerebellar cortex development] evidence: IBA
GeneID:85458 -> Biological process: GO:0030900 [forebrain development] evidence: IBA
GeneID:85458 -> Biological process: GO:0043010 [camera-type eye development] evidence: IBA
GeneID:85458 -> Biological process: GO:0046328 [regulation of JNK cascade] evidence: IBA
GeneID:85458 -> Biological process: GO:0050772 [positive regulation of axonogenesis] evidence: IBA
GeneID:85458 -> Biological process: GO:0060071 [Wnt receptor signaling pathway, planar cell polarity pathway] evidence: IRD
GeneID:85458 -> Biological process: GO:0090263 [positive regulation of canonical Wnt receptor signaling pathway] evidence: IDA
GeneID:85458 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
GeneID:85458 -> Cellular component: GO:0005925 [focal adhesion] evidence: IEA
GeneID:85458 -> Cellular component: GO:0005938 [cell cortex] evidence: IBA
GeneID:85458 -> Cellular component: GO:0043025 [neuronal cell body] evidence: IBA
GeneID:85458 -> Cellular component: GO:0043679 [axon terminus] evidence: IBA
by
@meso_cacase at
DBCLS
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