LOCUS       XM_039079020            4381 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus phosphatidylinositol-4-phosphate
            5-kinase type 1 gamma (Pip5k1c), transcript variant X2, mRNA.
ACCESSION   XM_039079020
VERSION     XM_039079020.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4381
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /country="USA: Wisconsin, Milwaukee, Medical College of
                     Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4381
                     /gene="Pip5k1c"
                     /note="phosphatidylinositol-4-phosphate 5-kinase type 1
                     gamma; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 43 ESTs, 6 long SRA reads,
                     11 Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 27 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:314641"
                     /db_xref="RGD:1309938"
     CDS             104..2176
                     /gene="Pip5k1c"
                     /codon_start=1
                     /product="phosphatidylinositol 4-phosphate 5-kinase type-1
                     gamma isoform X2"
                     /protein_id="XP_038934948.1"
                     /db_xref="GeneID:314641"
                     /db_xref="RGD:1309938"
                     /translation="

MELEVPDEAESAEAGAVTAEAAWSAESGAAAGMTQKKAILAEAPLVTGQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAEGAQSKADEKRPVAQKALYSTAMESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSSSLKSSPSKKGRGALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSDTSEQPRRRTQSSGQDGRPQEELHAEDLQKITVQVEPVCGVGVVVPKEQGAGVEVPPSGASAAATVEVDAASQASEPASQASDEEDAPSTDIYFFAHGRYWLFSPRRRQLRAVTPSHTGAPTDERSWVYSPLHYSARPASDGESDTVSPQ"

     misc_feature    329..1450
                     /gene="Pip5k1c"
                     /note="Phosphatidylinositol phosphate kinase (PIPK)
                     catalytic domain found in phosphatidylinositol 4-phosphate
                     5-kinase type-1 gamma (PIP5K1gamma) and similar proteins;
                     Region: PIPKc_PIP5K1C; cd17308"
                     /db_xref="CDD:340445"
     misc_feature    order(401..418,422..424,530..532,710..712,719..724,
                     734..739,1013..1015,1022..1024,1034..1036)
                     /gene="Pip5k1c"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:340445"
     misc_feature    order(611..622,626..628,632..634,659..661,665..667,
                     815..826,860..862,923..925,1061..1063,1292..1297)
                     /gene="Pip5k1c"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:340445"
     misc_feature    order(665..667,1049..1051,1295..1297)
                     /gene="Pip5k1c"
                     /note="catalytic core residues [active]"
                     /db_xref="CDD:340445"
ORIGIN      

ccgccctatagtgcgggcggcgcttgttgttcagcggcggcggccgagctcgggtgcatcctcgggcccgccgccgccgccgctgccgccggagcgcgcggccatggagctagaggtgccggacgaggcagagagcgccgaagcaggggccgtgacagcggaggcggcctggtctgcggagagtggggcggcggcaggtatgacccagaagaaggctatccttgcagaggccccgttggtgacagggcagccaggccctggccatgggaagaagctgggccatcgaggcgtggatgcgtctggagagactacgtataagaagaccacctcgtccaccctgaagggtgccatccaactggggattgggtacacggtgggcaacctcagctctaagccagaacgcgatgtgctcatgcaggacttctatgtggtggagagcatcttctttcccagcgaagggagcaaccttacccccgcccaccacttccaggatttccgtttcaagacctatgcacctgttgccttccgttacttccgggagctctttggtatccgtccggacgattacttgtactcactctgcaacgagccactcattgagctgtccaacccgggtgccagtggctccgtcttctacgtcaccagcgatgacgagttcatcattaagactgtcatgcacaaggaggcggagttcctgcagaaactgctgcctggctactatatgaacctcaaccagaacccccggaccttgctgcccaagttctatgggctgtactgtgtgcagtccggcggcaagaacattcgagtggtggtcatgaacaatgtgctgccccgtgtcgtcaagatgcacctcaagttcgacctcaagggctccacgtacaagcgcagggccagcaagaaggagaaggagaagagcctgcccacctacaaggacctggacttcatgcaggacatgccagaggggctgctactggactctgacacctttggcgccctggtcaagacgctgcagcgagactgcctggtgttggagagcttcaagataatggactacagcctgctgctgggtgtgcacaacattgaccagcaggagcgggagcgccaggccgagggcgcccagagcaaggctgacgagaagcggccggtggcccagaaggccctctactccacagccatggagtccattcagggcggagctgcccgtggggaggccattgagacagatgacacgatgggtgggatcccagccgtgaatgggcgtggggagcgcttgctcctacacatcggaatcattgacattctgcagtcctacaggttcatcaagaagttagaacacacctggaaggccctcgtccacgatggggataccgtctcagtccaccggcccagcttctatgccgagcgcttcttcaagttcatgagcagcacggtcttccggaagagttcctccctcaagtcctctccatctaagaaagggcgtggcgccctgctcgcagtcaagcccctggggcccaccgcagccttctcagctagccagatccccagtgagagagaggatgtgcagtacgacctgcggggagcccgcagctaccccacgctggaggatgaaggccggcctgacctcctgccctgcaccccaccgtcctttgaggaagccaccacagcctctatcgccaccaccctgtcatccacctccctctccatcccagagcggtccccttcagacacatcagagcagccccggcggcgtacgcagtcttcaggccaggatggccggccccaggaggagctgcatgcggaagacctgcagaagataactgtgcaggtggagccagtgtgtggtgtgggggttgtcgtccccaaggagcagggtgcaggagtggaggttcccccatctggggcatcggcagcagccacggtggaagtagacgctgccagccaggcctcagagcccgccagccaagcctctgatgaggaagatgcgccttccacagacatctattttttcgcccacgggagatactggcttttctctccccgtcgtcgccaactgcgggccgtgacaccaagccacacaggcgctcccaccgacgagaggagctgggtgtactccccgcttcactatagcgcacggcccgcctccgacggcgagagcgacacagtaagtccccagtaacttctatgcagtccccaatctggagcccagcgtccttctgccaccccagccacttcctggaggcgctgccccccactggggctcagagctcagcgacatcaccccgatggccctggcccgaccttgttctctccctccccactgacggacgccattggccaggcccagccccaggataggtcaggcctccatctgctgctacctgtgcctgttggggcggcaagatttggagtgcacattctgtatttattttgggtccacccctcccccccctttttttggacggagagggagcacaggagtgtttttctaggaaaaagacaagacacaaaaaacccaggaagaggctgcagccaccagccttggtggatcaggttctatgtgtctcagtaccctggggacagtggccaggtagctccagtaaaccccacacactccagagctcgttatgactggcagaggagacaggccctggagccgcggcttgccgtcccgggtctgtgttcctgagttgggtcgcctcaacagagcccctccttcacctcaggtttgggacccaagcaaaccaggactagtcatgccctgtggtctttctgcatctgtttactgccactggaaggatgtccctacgcatgtcttgtggctacaatcacctgatgctgactgggaggttccatattgtctgcctctcatccccatgaaaccctgagctggtgctgtgggtcccctcaactcccagggaaatctctgcccccaagaagggcacagccaggcttcaggctgcagagtgagagtttggtccttaccttggttgaagagagtaagaaagggacatcacctcagcaaagccaaccatatctactgaccaccagggagatcgcagcaagcattctccactgggcagaccccagtgtgttgggtgcagtccagctatgctatgcctctgtttcgtggatgttccacccacggtaggcggagtcaagcaggaatgttctgaaagcacgcagccacaggacacaacctttgggtcagcttcatgggcctcttgggttgcaccttcagggacaggggctatctggcttccaaggactgtagcagcctgtggaggcagtgtggagcatgacactgccatcgtggccagaaaaggcatggccagggagaggacccctggagggggagagtaggagagatgggcagatgcctgtccctggacctcacatcagcccccttcctgttgaggaatgcacagtgaacacaccgtggggagctgctgcatgagttaactaaggggttggggcttgcacacaccaggcaagcatgtcacacctgccatccctgaacttggaaagttaaggcaggagggttgtggcaagttccaggctcgcgtgggttagagtaaaacgagaccaaaaggaaaaaaaaaatcacagggctggccctaccactcagtgggcagaactcacccagctgcataaaccctgagttccattccagcaccacagaaaccagattgggaggcacacagctgccatccctcgcttgggaaacaggcagaaagagcaggagtgcaaggccatccttggctgtatccagttgaaggccagcctgggctacatgagactctctcaaaagagaatctgtaaatatcttcgtgaccccacctcccatcctgttctctatgatggccgctatcgccccaccgtggacggtgtgtgaactgtactgtaaaggcctgcctgggggcgcctccaaggctgaagaggtgccctccccggcccgcctctgttctcctcaagccatcccagcaagtcccctgtccagccccacaccaacctcagtgcaatatgcccttcccgtggggtcccctggcacggtactgtctctgcagccccttgtctcttacccctagctcctctctcccagtggttaaaaatcacatcgcacatcctcccccacatcctgtttttattgttgaatccattctgtaaactacaaacctcctgtgtcttactcatcaggaatagggatcccgggtcctcagcccatgtgatctggtgtttgacaatccaagtacagtgtccccttggcaccaaccagtggggcctgtccctccagcgcagccggcaaatgtatgcagcccaggttcccgctccacctgtcacacccctctttttgagatctgtaataaatctctaataagaaaca

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