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Previous release (v1)
2024-04-28 05:57:43, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NM_001109908 1803 bp mRNA linear ROD 16-DEC-2022
DEFINITION Rattus norvegicus enolase 1 (Eno1), transcript variant 2, mRNA.
ACCESSION NM_001109908
VERSION NM_001109908.1
KEYWORDS RefSeq.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 1803)
AUTHORS Li L, Luo Y, Zhang Y, Wei M, Zhang M, Liu H and Su Z.
TITLE CircZNF609 aggravates neuropathic pain via miR-22-3p/ENO1 axis in
CCI rat models
JOURNAL Gene 763, 145069 (2020)
PUBMED 32827683
REMARK GeneRIF: CircZNF609 aggravates neuropathic pain via miR-22-3p/ENO1
axis in CCI rat models.
REFERENCE 2 (bases 1 to 1803)
AUTHORS El Waly B, Mignon-Ravix C, Cacciagli P, Buhler E, Ben Zeev B and
Villard L.
TITLE Molecular characterization of a 1p36 chromosomal duplication and in
utero interference define ENO1 as a candidate gene for
polymicrogyria
JOURNAL Eur J Hum Genet 28 (12), 1703-1713 (2020)
PUBMED 32488097
REMARK GeneRIF: Molecular characterization of a 1p36 chromosomal
duplication and in utero interference define ENO1 as a candidate
gene for polymicrogyria.
REFERENCE 3 (bases 1 to 1803)
AUTHORS Zhang ZH, Zhang H, Wang YR, Liu XL, Huang H and Xu XH.
TITLE SIRT 1 binding with PKM and NSE and modulate their acetylation and
activities
JOURNAL Biochim Biophys Acta Proteins Proteom 1867 (9), 794-801 (2019)
PUBMED 31202897
REMARK GeneRIF: SIRT1 may regulate acetylation level of NSE and PKM
through deacetylation and further regulate their catalytic
activity.
REFERENCE 4 (bases 1 to 1803)
AUTHORS Dai J, Zhou Q, Chen J, Rexius-Hall ML, Rehman J and Zhou G.
TITLE Alpha-enolase regulates the malignant phenotype of pulmonary artery
smooth muscle cells via the AMPK-Akt pathway
JOURNAL Nat Commun 9 (1), 3850 (2018)
PUBMED 30242159
REMARK GeneRIF: regulates the metabolic reprogramming and malignant
phenotype of pulmonary artery smooth muscle cells in pulmonary
arterial hypertension
Publication Status: Online-Only
REFERENCE 5 (bases 1 to 1803)
AUTHORS Huang H, Tang S, Ji M, Tang Z, Shimada M, Liu X, Qi S, Locasale JW,
Roeder RG, Zhao Y and Li X.
TITLE p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis
JOURNAL Mol Cell 70 (4), 663-678 (2018)
PUBMED 29775581
REMARK Erratum:[Mol Cell. 2018 Jun 7;70(5):984. Title and abstract
corrected. PMID: 29883613]
REFERENCE 6 (bases 1 to 1803)
AUTHORS Ray R and Miller DM.
TITLE Cloning and characterization of a human c-myc promoter-binding
protein
JOURNAL Mol Cell Biol 11 (4), 2154-2161 (1991)
PUBMED 2005901
REFERENCE 7 (bases 1 to 1803)
AUTHORS Berry MN, Gregory RB, Grivell AR, Henly DC, Phillips JW, Wallace PG
and Welch GR.
TITLE Evidence that stimulation of gluconeogenesis by fatty acid is
mediated through thermodynamic mechanisms
JOURNAL FEBS Lett 231 (1), 19-24 (1988)
PUBMED 2966075
REFERENCE 8 (bases 1 to 1803)
AUTHORS Giallongo,A., Feo,S., Moore,R., Croce,C.M. and Showe,L.C.
TITLE Molecular cloning and nucleotide sequence of a full-length cDNA for
human alpha enolase
JOURNAL Proc Natl Acad Sci U S A 83 (18), 6741-6745 (1986)
PUBMED 3529090
REFERENCE 9 (bases 1 to 1803)
AUTHORS Sakimura,K., Kushiya,E., Obinata,M. and Takahashi,Y.
TITLE Molecular cloning and the nucleotide sequence of cDNA to mRNA for
non-neuronal enolase (alpha alpha enolase) of rat brain and liver
JOURNAL Nucleic Acids Res 13 (12), 4365-4378 (1985)
PUBMED 2989793
REFERENCE 10 (bases 1 to 1803)
AUTHORS Jorgensen,O.S. and Centervall,G.
TITLE Alpha gamma-enolase in the rat: ontogeny and tissue distribution
JOURNAL J Neurochem 39 (2), 537-542 (1982)
PUBMED 7086434
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BC078896.1.
Transcript Variant: This variant (2) differs in the 5' UTR compared
to variant 1. Variants 1 and 2 encode the same protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC078896.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMD00132262, SAMD00132275
[ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..1803
/organism="Rattus norvegicus"
/mol_type="mRNA"
/db_xref="taxon:10116"
/chromosome="5"
/map="5q36"
gene 1..1803
/gene="Eno1"
/gene_synonym="Nne"
/note="enolase 1"
/db_xref="GeneID:24333"
/db_xref="RGD:2553"
exon 1..161
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
misc_feature 90..92
/gene="Eno1"
/gene_synonym="Nne"
/note="upstream in-frame stop codon"
exon 162..255
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
CDS 171..1475
/gene="Eno1"
/gene_synonym="Nne"
/EC_number="4.2.1.11"
/note="non-neural enolase; 2-phospho-D-glycerate
hydro-lyase; enolase 1, alpha non-neuron; enolase 1,
(alpha)"
/codon_start=1
/product="alpha-enolase"
/protein_id="NP_001103378.1"
/db_xref="GeneID:24333"
/db_xref="RGD:2553"
/translation="
MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSPDDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK"
misc_feature 174..1466
/gene="Eno1"
/gene_synonym="Nne"
/note="enolase; Region: PLN00191"
/db_xref="CDD:215095"
misc_feature 174..176
/gene="Eno1"
/gene_synonym="Nne"
/note="N-acetylserine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 183..185
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 300..302
/gene="Eno1"
/gene_synonym="Nne"
/note="Phosphotyrosine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); phosphorylation site"
misc_feature 348..350
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine, alternate.
/evidence=ECO:0000250|UniProtKB:P17182; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 360..362
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 381..383
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 435..437
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine, alternate.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 546..548
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 747..749
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 765..767
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 774..776
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine, alternate.
/evidence=ECO:0000250|UniProtKB:P17182; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 852..854
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine, alternate.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 867..869
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine, alternate.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 936..938
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 957..959
/gene="Eno1"
/gene_synonym="Nne"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); phosphorylation site"
misc_feature 1011..1013
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine, alternate.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 1023..1025
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 1029..1031
/gene="Eno1"
/gene_synonym="Nne"
/note="Phosphotyrosine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); phosphorylation site"
misc_feature 1041..1043
/gene="Eno1"
/gene_synonym="Nne"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); phosphorylation site"
misc_feature 1173..1175
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P17182; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 1197..1199
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P17182; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 1383..1472
/gene="Eno1"
/gene_synonym="Nne"
/note="propagated from UniProtKB/Swiss-Prot (P04764.4);
Region: Required for interaction with PLG.
/evidence=ECO:0000269|PubMed:7964722"
misc_feature 1386..1388
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:P17182; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
misc_feature 1428..1430
/gene="Eno1"
/gene_synonym="Nne"
/note="N6-acetyllysine, alternate.
/evidence=ECO:0000250|UniProtKB:P06733; propagated from
UniProtKB/Swiss-Prot (P04764.4); acetylation site"
exon 256..351
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 352..410
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 411..480
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 481..614
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 615..837
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 838..1035
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 1036..1237
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 1238..1346
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 1347..1405
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
exon 1406..1780
/gene="Eno1"
/gene_synonym="Nne"
/inference="alignment:Splign:2.1.0"
ORIGIN
ggcccctaggccgcgcatcaacgtttccacaccgccgggggctccagcacctcccggcggggggggaggcccacaggaaggcccagccctaaaggtcatcagcaaggtcgtgggccggacgtgaggcgctgcagcccggccgagtgcgtgtaggactcggaaacttcaccatgtccattctcaagatccatgccagagagatctttgactcccgcgggaatcccaccgttgaggtggatctctacaccgcaaaaggtctcttccgtgctgcggtgcccagcggtgcgtccactggcatctacgaggccctagaactccgagacaatgataagacccgcttcatggggaagggtgtctcaaaggctgttgagcacatcaataaaactattgcacctgctctggttagcaagaaactgaatgttgtggagcaggagaagattgaccagctgatgatcgagatggacggcacagagaataaatctaagtttggtgcaaatgccatcctgggagtgtccctggctgtctgcaaggctggtgccgtggagaagggggtgcccctttaccgtcacattgccgacttggccggcaaccctgaagtcatcctgccggtcccagctttcaatgtgatcaacggcggttctcatgctggcaacaagttggccatgcaagagttcatgatcctgcctgtgggggcatcctctttccgggaagccatgcgcattggagcagaggtttaccacaacctgaagaacgtcatcaaggagaagtacgggaaagacgccaccaatgtgggtgatgagggtggattcgcacctaacatcctggagaacaaagaagcactggagctgctcaagtctgccattgcaaaggccggctacactgaccaggttgtcatcggcatggatgtggctgcctccgagttctacagggctggcaagtatgacctggacttcaagtctccagatgatgccagccggtacatcacacccgaccagctggccgacctgtacaagtccttcatcaaggactacccagtggtgtccattgaagatccctttgaccaggacgactgggatgcttggcagaagttcacagctactgcaggcatccaggtggtgggggatgacctcacagtgaccaaccctaagcggatcgccaaggctgcaggcgaaaagtcctgcaactgcctcctgctcaaagtgaaccagattggctctgtgaccgagtctctgcaggcgtgtaagctggcccagtccaatggctggggtgtcatggtgtcccatcgatctggggagactgaggacactttcattgccgacctggtggtggggctctgcactgggcagatcaagactggtgccccctgccgatctgagcgcctggccaagtacaatcagatccttagaatcgaggaggagctgggcagcaaagccaagtttgccggcaggtccttcaggaaccccctggccaagtaaggcatggaccggagatccctggagctaccagatcctctgtctctgtcatccaggcggctcaaggctggcccagtgcttgcccctcccatgtcactgcttccttagatgtccaccccgaccacctggagccctgctggagcccccagctttgtaatcatgtgatcagtctgaatcattgtttctgtcacctgactttccagctagtgtctggagccctctgaactccagcgtaatctctagggtgcccacaccatcaagactccccccagtggtttacttgcaaaaataaaagctgcagaagcccaaaaaaaaaaaaaaaaaaaaaaaa
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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