LOCUS       NM_001106244             799 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus RNA polymerase II subunit I (Polr2i), mRNA.
ACCESSION   NM_001106244 XM_001075773 XM_214895
VERSION     NM_001106244.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 799)
  AUTHORS   Kershnar E, Wu SY and Chiang CM.
  TITLE     Immunoaffinity purification and functional characterization of
            human transcription factor IIH and RNA polymerase II from clonal
            cell lines that conditionally express epitope-tagged subunits of
            the multiprotein complexes
  JOURNAL   J Biol Chem 273 (51), 34444-34453 (1998)
   PUBMED   9852112
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214895.4, XM_001075773.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM052786.1, FM058925.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..799
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..799
                     /gene="Polr2i"
                     /note="RNA polymerase II subunit I"
                     /db_xref="GeneID:292778"
                     /db_xref="RGD:1309395"
     exon            1..437
                     /gene="Polr2i"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    298..300
                     /gene="Polr2i"
                     /note="upstream in-frame stop codon"
     CDS             379..756
                     /gene="Polr2i"
                     /EC_number="2.7.7.6"
                     /note="polymerase (RNA) II (DNA directed) polypeptide I,
                     14.5kDa; polymerase (RNA) II subunit I"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase II subunit RPB9"
                     /protein_id="NP_001099714.1"
                     /db_xref="GeneID:292778"
                     /db_xref="RGD:1309395"
                     /translation="

MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE"

     misc_feature    418..753
                     /gene="Polr2i"
                     /note="DNA-directed RNA polymerase, subunit
                     M/Transcription elongation factor TFIIS [Transcription];
                     Region: RPB9; COG1594"
                     /db_xref="CDD:224510"
     misc_feature    598..750
                     /gene="Polr2i"
                     /note="C-terminal zinc ribbon domain of RPB9 subunit of
                     RNA polymerase II; Region: Zn-ribbon_RPB9; cd10508"
                     /db_xref="CDD:259793"
     misc_feature    order(598..600,604..609,613..615,667..672,676..678,
                     700..708)
                     /gene="Polr2i"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:259793"
     misc_feature    order(634..636,643..645,718..720,733..735)
                     /gene="Polr2i"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:259793"
     exon            438..492
                     /gene="Polr2i"
                     /inference="alignment:Splign:2.1.0"
     exon            493..566
                     /gene="Polr2i"
                     /inference="alignment:Splign:2.1.0"
     exon            567..641
                     /gene="Polr2i"
                     /inference="alignment:Splign:2.1.0"
     exon            642..693
                     /gene="Polr2i"
                     /inference="alignment:Splign:2.1.0"
     exon            694..799
                     /gene="Polr2i"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggaggccgacgccggggagaatggctggagttatcctggcccgccgagtataagctcggcgcatgtgcactggccttgggccaagaagagagcggtggcttctcccgtttatgctcagcgccttgtggatgacgttgcgcgtcacagtcccagcccttgtcctaaatccaaaccactcggagttgtgaagcaaggttccgaaataatcgggagtaggtatcaaaggatagacgcaagccgtcagccagacatccataagataaggagccctcacgtgcacgcagctccgccccattttagtgcagctacgcgatccgacccttcccgcggtccgtagcgcggccgcgcaagcgcagaaaggtaatcagcccagtcgctatggaacctgacgggacgtacgagcctggcttcgtcggtattcggttctgccaggaatgtaataacatgctgtaccccaaggaggacaaggagaatcgcattctgctgtacgcgtgccggaattgcgattaccagcaggaagccgacaacagctgcatctacgtcaacaaaatcacgcacgaagtggacgagctgacccagatcatcgcagacgtgtcccaggaccctacgttgccccggaccgaggaccacccgtgccagaagtgtggccacaaggaggcagtgttcttccagtcacacagtgcccgagctgaggatgccatgcgcctgtactatgtatgcaccgccccacactgcggccaccgctggactgagtgaccgttccttcctccatttgtaataaatgcccagtttccacact

//