LOCUS       NM_001098667            3768 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus zinc finger and BTB domain containing 24
            (Zbtb24), mRNA.
ACCESSION   NM_001098667 XM_039098906 XM_345114
VERSION     NM_001098667.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3768)
  AUTHORS   Nagamachi A, Matsui H, Asou H, Ozaki Y, Aki D, Kanai A, Takubo K,
            Suda T, Nakamura T, Wolff L, Honda H and Inaba T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   2  (bases 1 to 3768)
  AUTHORS   Edgar AJ, Dover SL, Lodrick MN, McKay IJ, Hughes FJ and Turner W.
  TITLE     Bone morphogenetic protein-2 induces expression of murine zinc
            finger transcription factor ZNF450
  JOURNAL   J Cell Biochem 94 (1), 202-215 (2005)
   PUBMED   15526281
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000330.1.
            
            On or before Mar 10, 2021 this sequence version replaced
            XM_039098906.1, NM_001098667.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK001278.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132273, SAMD00132280
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-150               JACYVU010000330.1  107599-107748
            151-1130            JACYVU010000330.1  108276-109255
            1131-1298           JACYVU010000330.1  112974-113141
            1299-1382           JACYVU010000330.1  113533-113616
            1383-1466           JACYVU010000330.1  114394-114477
            1467-1548           JACYVU010000330.1  120102-120183
            1549-3768           JACYVU010000330.1  122046-124265
FEATURES             Location/Qualifiers
     source          1..3768
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q12"
     gene            1..3768
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="zinc finger and BTB domain containing 24"
                     /db_xref="GeneID:365590"
                     /db_xref="RGD:1306951"
     exon            1..150
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /inference="alignment:Splign:2.1.0"
     exon            151..1130
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /inference="alignment:Splign:2.1.0"
     CDS             182..2314
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="zinc finger protein 450; bone morphogenetic
                     protein-induced factor 1"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein
                     24"
                     /protein_id="NP_001092137.2"
                     /db_xref="GeneID:365590"
                     /db_xref="RGD:1306951"
                     /translation="

MADTTPEPSGHLIVHSDTHSDTVLASLEDQRKKGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGYLHASEKMTEQILATAQFLKVYDLVKAYTDFQNSHNSPKPPALNCSGTPVVVISNKKNDPLKRKRGRPRKTNSLQEGKSELAAEGEVQLRVNNSVQNRQNFVFKEDSVRLNEQTPKEKELEPAGEPGSVEEMPAEKDENSDPKARDGPGSQSRYSKRRTRRSVKLKDYKLSGDEDDQSTAKRATCGRQKRSSAPEARCKDCDRVFKYSHFLAIHQRRHTGERPFKCSECGKGFAQKHSLQVHTRMHTGERPYTCTVCSKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECNHCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKCFSDSSAKRRHCVLHTGKKPFSCPECSLQFARLDNLKAHLKIHSKEKHASDSSSVSGSSADEVRNVLQLQPYQLSASGEQEIQLLVTDSVHNINFMPTPSQGVSIVAAESSQNMATDPAANITLLTQQPEQLQGLILSAQQEQTEHIQSLGMIGSQMDTSQTEPVHVITLSKETLEHLHAHQEQTSSSVPAADTGARASSPPSTRPGAELTQAPLTVPLDPSPGATVAGWPFGPSSYRSLKM"

     misc_feature    221..571
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ
                     (poxvirus and zinc finger) domain found in zinc finger and
                     BTB domain-containing protein 24 (ZBTB24); Region:
                     BTB_POZ_ZBTB24_ZNF450; cd18212"
                     /db_xref="CDD:349521"
     misc_feature    632..715
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3B725.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    788..1039
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3B725.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1064..>1198
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="N-terminal domain of Oryza sativa transcription
                     factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana
                     SUF4 (AtSUF4), and similar proteins; Region: SUF4-like;
                     cd20908"
                     /db_xref="CDD:411020"
     misc_feature    1064..1126
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:411020"
     misc_feature    1064..1126
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    order(1079..1081,1085..1087,1091..1093,1097..1102,
                     1109..1114,1121..1123,1163..1165,1169..1171,1181..1186,
                     1193..1198,1205..1207,1247..1249,1253..1255,1259..1261,
                     1265..1270,1277..1282,1289..1291)
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:275368"
     misc_feature    order(1079..1081,1097..1099,1118..1120,1121..1123,
                     1145..1147,1166..1168)
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:411020"
     misc_feature    <1139..1618
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="FOG: Zn-finger [General function prediction only];
                     Region: COG5048"
                     /db_xref="CDD:227381"
     misc_feature    1148..1210
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1232..1294
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1316..1378
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1400..1462
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    order(1415..1417,1421..1423,1427..1429,1433..1438,
                     1445..1450,1457..1459,1499..1501,1505..1507,1517..1522,
                     1529..1534,1541..1543,1583..1585,1589..1591,1595..1597,
                     1601..1606,1613..1618)
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:275368"
     misc_feature    1484..1546
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1568..1618
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1610..1681
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="Zinc-finger double domain; Region: zf-H2C2_2;
                     pfam13465"
                     /db_xref="CDD:433230"
     misc_feature    1652..1714
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    2117..2254
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3B725.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            1131..1298
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1382
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1466
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1548
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..3768
                     /gene="Zbtb24"
                     /gene_synonym="Bif1a; ZNF450"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

tgcgcgcgcttccgggctgacagtcgccgggagccgggagcttacgcgcagtggtgccgggggcgtggatcggcgacaggcccggcttggtgtcctctgggcagcccggtggactgactgtagtaggaccccgccggccggccctgacagatttaaacctcttcggagtcttctggagaaaatggcggacacaacacctgagccttctgggcatcttattgtacactcagacactcacagtgacactgtcctggctagtcttgaggatcagaggaagaagggctttctttgcgatattactttgatcgtggagaatgtgcatttccgagctcataaagccctactggctgccagtagcgagtatttctcaatgatgtttgcggaagagggcgagattggccagtccatttatatgctggaaggcatggttgcagacacctttggtatcctgctggaatttatctatacaggttatctacatgccagtgagaaaatgacagaacaaatcctggctactgcccaattcttaaaagtctatgacctggtaaaggcttacaccgacttccagaatagccataactccccaaagccaccggccttgaactgctcaggtactccggtggtggttatttccaataagaagaatgatcctctgaaacggaaacggggaaggccaagaaaaaccaacagtttgcaggaagggaaatcggagctagctgcagagggagaggtgcagctaagagtgaacaattccgttcagaatagacaaaactttgtatttaaagaagacagtgtcagactgaatgagcagactcccaaagaaaaggagttggagcctgccggtgagccaggcagtgtggaggagatgcctgccgagaaggacgagaactctgaccccaaggctcgggatggaccgggaagccagagcaggtacagcaagcggaggactcgcaggtctgtcaagcttaaagactacaaacttagtggagatgaagatgaccagagcacagccaagagggcgacgtgtgggaggcaaaagcgttccagcgctcccgaggcccgctgtaaagactgcgacagagtctttaaatatagtcacttcttagccatccaccagagacgccacactggggagcgacccttcaaatgcagtgagtgtggaaagggctttgctcagaagcactccttgcaggttcacaccaggatgcacacgggggagcggccatacacctgcaccgtgtgcagcaaggcgctgaccaccaagcactccctgctggagcacatgagcctgcactcagggcagaagtcttttacctgtgatcagtgtggaaagtatttcagccagaaaagacagctaaagagccattatcgtgtccatacaggccactcactaccagaatgcaaccactgccatcgcaagtttatggatgtgtcccagctaaagaaacatctgcggacgcacacaggtgagaagccatttacttgtgaaatctgtgggaaatctttcacagcaaagagctccctccagacccacatcagaatccaccgaggagaaaagccgtactcctgcagcatctgcggcaaatgcttctctgactccagtgccaagaggagacactgcgtcttacatacgggcaaaaagcctttctcctgccctgagtgtagcctacagtttgctcgcctagacaatttgaaggctcacctgaaaatccacagcaaggagaagcacgcgtcagactccagcagtgtttctggcagtagtgctgacgaggtgcggaacgttcttcagctgcagccataccagctctccgcctcaggagagcaggagattcagcttctcgttaccgactctgtgcataacattaacttcatgcccactcccagccagggagttagcattgtagctgctgagagctctcagaacatggccacagacccggctgccaacatcaccctgctcacacagcagccggagcaactgcagggcctgattctttcagctcagcaggagcagacagagcacattcagagcctcggcatgattggaagccagatggacacctcccagaccgagccagtgcatgtgatcacactgtccaaggaaacgctggagcacctccatgctcaccaggagcaaacatccagctcagtgcctgcagcggacacaggagcccgagcctcctctcccccctccactaggccaggggcagagctgacacaggcacctctgactgttcccctggacccttcccctggagccacagtggcggggtggccctttgggccgtcctcttatagatccttaaagatgtgatctgccccttacttataatgggctccgtcagggcagagtctgtcttatctataacatcaactcatatttggcatttaaatattgatgagggtttccactttgatctactatctgctcttcaggattggtagttttccttcaggggcattgattttattatacttttctgtaagtgttgaatgtccacagccatagagtatggtctggtttagaaccaacagagtcgtgcctggggtgcatctttgggtatagtggggttatttctcttgggcagtatgcttgccattcccaaacgagtcagccctactgtaagtgatcacggcaagattcccctccaggaacttacccctaagagagcgcctcttggatttatctctgtgtggtacggcggggcgggctgaccgtgttgcactgaagctatcttgtcatgctcacaaaccatactcgcgacacaaaagccaaagtaactttaaaggttttgaatacaactttgcttcaaaacgtggatttatacatttttttttaaagaagcaggctattaaattttattttaaaaaatctccggggctggggatttagctcagtggtagagcgcttacctaggaagcgcaaggccctgggttcggtccccagctccgaaaaaaaagaaccaaaaaaaaaaaaaaaaaaaatctccaaagtatgaaactggatcaagatactcattccaaataaaccaaattttgtcagataatgatacttgatttttatcaaaaagaagtcttagttacctggaactttaaagtttctcagtgtaccataagtcctaaatgcactgctgacttgtacttgagcgcagcattctgagttccgcgtccatcgtccatcgtaggactcctgcaggaagaactgggctctgtctgcatggccgtccaggttaaccccactccacaccgcttccttctgagcctcagagcgaaagcagccgcctgcgtccatgatggagggactttcaagccaacactaagttatgtctgggttctgttttcacgatcactgcactagttgaattcttggacttctcaggaagctggcggccttgcttgaggaaagagatagggtgctgggaacacggtgcaggggaccgtcggtgtgaactcgtgtcttcacagccgtcattcttcttcccttcgtgtattcccagccaaatccactatatttctgcaaattaaagaactagacaattcttcacattagcaagaacatttttgttctatatgcaccgagttgttttattagacataatttataaattgaataccaagttgtagatacggatcggctgtgtaatgtgcactctgatctgactggcacaaatgctgcttccctttagtaatttagactcagtttagtcatttgagctatgtattcactgtgacgtgtgagcatggcttatatacaggccttatcccctg

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