2024-11-01 07:50:08, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS XM_036164539 5181 bp mRNA linear ROD 07-FEB-2024 DEFINITION PREDICTED: Mus musculus argonaute RISC catalytic subunit 4 (Ago4), transcript variant X6, mRNA. ACCESSION XM_036164539 VERSION XM_036164539.1 DBLINK BioProject: PRJNA169 KEYWORDS RefSeq. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_000001635.27-RS_2024_02 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.2 Annotation Method :: Best-placed RefSeq; Gnomon; RefSeqFE; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 02/01/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5181 /organism="Mus musculus" /mol_type="mRNA" /strain="C57BL/6J" /db_xref="taxon:10090" /chromosome="4" gene 1..5181 /gene="Ago4" /gene_synonym="5730550L01Rik; Eif2c4" /note="argonaute RISC catalytic subunit 4; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 2 mRNAs, 4 ESTs, 22 long SRA reads, 2 Proteins, and 99% coverage of the annotated genomic feature by RNAseq alignments, including 31 samples with support for all annotated introns" /db_xref="GeneID:76850" /db_xref="MGI:MGI:1924100" CDS 306..1523 /gene="Ago4" /gene_synonym="5730550L01Rik; Eif2c4" /codon_start=1 /product="protein argonaute-4 isoform X5" /protein_id="XP_036020432.1" /db_xref="GeneID:76850" /db_xref="MGI:MGI:1924100" /translation="
MEAGSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKMNAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEITQELLYSQEVVQDLTSMARELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKMERVGKSGNVPAGTTVDSTVTHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA"
misc_feature 318..1394 /gene="Ago4" /gene_synonym="5730550L01Rik; Eif2c4" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(498..500,510..512,546..557,564..566,588..590, 597..599,609..611,621..623) /gene="Ago4" /gene_synonym="5730550L01Rik; Eif2c4" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(702..704,708..710,948..950,1362..1364) /gene="Ago4" /gene_synonym="5730550L01Rik; Eif2c4" /note="active site" /db_xref="CDD:240015" ORIGIN
ggcaagatctgctcctgacagacaggaggaaatcagtagactggtcagtaaggcgtgtcttcaacattagccatctgtgagctgaaaaaacaaaacaaaacaaaacaaaacctaaaaaagaataaacagctctggaggggacacagttcctgtcagctcttatagatgcaggctttccattccttaggtgaagagcaacagcatggtgggtggacctgacccatacctgaaggaatttgggattgttgtgcacaacgagatgacagagctcacaggcagggtgcttccggctccaatgctgcagtatggaggccgggagtttcactgaccaacttcgtaaaatctccaaggatgcagggatgcccatccagggtcagccatgtttctgcaagtatgctcaaggtgcagacagcgtggagcccatgtttaaacatctgaaaatgacatatgtgggcctgcagctaatagtggtgattttgcctgggaagacaccagtatatgcggaggtgaagcgtgttggagatacccttctaggtatggccacacagtgtgtccaggtcaaaaacgttgtgaagacctcgccccagaccctttccaacctttgcctgaagatgaacgcaaagctgggagggattaacaatgtgcttgtgcctcaccaaaggccctcagtgttccagcagcctgtcatctttctgggagcagatgtcactcatccgcctgctggggacgggaagaagccttctattgcagccgtggtgggcagcatggacggccatcccagccggtactgtgccacagtccgggtacagacatctcgacaggagatcacccaggagctcctctacagccaggaggtcgtgcaggacctgacgagcatggctcgggagctgctgattcaattctataagtccacgcgcttcaagcccacacgcatcatctactaccgcggaggggtatccgagggacagatgaagcaggtagcttggccggagctaatagcaattcgaaaggcatgtataagcttggaggaagactatcggccgggaataacttacattgtggtgcaaaagaggcaccacacacgactcttctgtgcagataaaatggaaagggtggggaaaagtggcaatgtcccagcaggcaccacagtggatagcaccgtcacacacccgtctgagtttgacttttacctctgtagtcatgcaggaattcagggaaccagccgtccttcacattaccaggtcttgtgggatgacaactgcttcactgcagatgaactccagctactgacttaccagctctgtcacacctacgtgaggtgcacacgctccgtctccattcctgcccctgcatattatgcccggcttgtggcattccgggcaaggtatcatttggtggataaagatcatgacagtgcggaaggcagtcacgtgtcaggacagagcaacggccgggatcctcaggccttggctaaggctgtgcagatccaccatgatacccagcacactatgtattttgcctgagagtcttggaaaagaactcaacaaatttggcatctcacgcatcctcaaaatgtttccgacgcctactgcctctctcaggtggtccctaccagcagctcagaatggttgcactgagtctactctgcagccctgtctgatacatcaacaaaattgagccagttgggtttttttgttaaagaaatagatactcatagattgtgttttctgatgcactgggcagaatttttacctcaacgtgcaaaggctgatcagccttgactttctaaaggactttccaagaagggtttctatggaatcttttgctagctgtggtattcaccgcatctagtcttataagaggagtatttccttttttctgtgtttattgaatggtgtgcataagtgggagagagaaaccaaacggcctgtatcatttccatgtaactttttaattgggtgggtccatagacctcttacttctgactttgccactgtcaatgcctttaaggagcatcagcttttgaaagttttacagaactctgttaccttcactgttctactgatctcttcgggcctgcactgtggggtacaggctgcccagcaattgcactatatttggctgcagattcgaacaggcagttcccttacttgactggcttttgtgagtctgtgacataagcagatgtgatgtgtgtcacagggacagatacactgccgtggtaaaaagtacccatgttttccatatttggaaaaagagaattagcttttagtatttttccacatcttcaaacatgcccattttatgctgctgtgtggtatgctagatctaaacgatctttaaacttctctcatagaaagttaactttggcaataagcatttgtaaggcccttgccctttctcctgacgtcgttttctagatgagatttcagtatgattttatcaactatttcttacatatcataactgggatattctgaaaccagtttataaagacacagatttcaatgtccttataaataattgtttttaaaacaaaacaaaacaaaacttattttatagtcagtgtcctgtcactttaaaaaaaaaaaaaagaagctggaaccaggatgctttgtgatcggtcaggctttgccgatgcataaggcacattgagcagtactgcacttgaaaagaaagtaccagccagtgaaaacctggtttccctgggaatcaggggtgcacacacggctgcctacaagacagcctgaaatgtgcttggtggctctgcctttctctttttcaactaaaactctgtagaagttgttgttgttgttgttgtttttctttttctgtaacagattctagattccctcacaggaagacaggattccgtttcttgtccaaacaaagggaattgatgtaaagcaagaacagttagaacatagggaaaatgtattctgtatttagtgtagataataccttgtaaaggacaagtgttacatagtcaaggtagttgcacccacggtttccagcccatgttttactctaacctggaaggtcaaggagtaaaaggtaagaggctctctgtagagccacactcctcatggctgaggagggtgctggggaaggaagagacaggcacaatatgctaaaagcaattttgcagtctcggtgtagaaaccattggtgggaaacactggatcaaatgggaaagggtgtttgcttgaactcattaattggtccaaggttcaaatctgttaaatgggccctctcagaatcccagcaatagaaagcactgtttcccttcagtggcttcagcaagtgtgtagatacattcatgtttacatttctgtgtgcagtcgctcagcagtgccactggtgtttgctgagcctggtctccgagagagtttataatgtccgtctagtcctatagcacatgcggatgggtgcagacatctttaatctctgcagacagtgggaaaagcaagtcctgtgactgaagcacaacacaggcgtgaagcgacagcagacgtccgttccctgagatcttcctttttttctgcaaatacctccctgggataatacaaatccagacatgttgatgaatggctgactgccgcttttattcacacctgttcagggaaagcacagaaaatgctctgtagcacagacattctggacccaagaggagggggaacaaaggaagcctttttaggaaaaggaaaacttgcctggagtctgtgatgtgaagaactctcggtggctggcagctgacagaaggcaccgtacctgcacaggagcgcctcgggcttgcttgttgacaatgcacagaagagactctagccatcttccgacaggatggaacagtgagcgagctgtgtgcccggaagccccatccacggtcctgcaactgagttgtaggtttgcccatgagcgatatgcctgaaacaccactgccggtcctagtatgctggggtgaatccgtgtggagctggaggaaaagccaggagaccaacttttgtagaaaaaacggtatcaataagtgtgtgaagccgttgttctgggcaagtggaaagaaatatggaagagttaggattacttgggggaggggaacttgctgaggggtgaacagtccagaggtgatcacttgagaatcagaactgcagtaataccaccgtaagcaaatctgaatgcatagttttaacttaactggggttgacaattcaaataggtacctccccccacccccccaaacaaaaacctgactgagttgttatgcatgtgtcaatcactgggaggtgtgcattctctagtagtgttaggctgtttggttcttttaaatgcagcctatttaggtactgtcatgtagtgtggaagattttggtgcggcaactctaaagaatgacatttttggggctagggagcataggacattaagaacgggaaagacccaagtgttgaaccaattgtgtttttttgttgttagttgttgaatcctgagttgatgcagtcagcattctgggcaggcgaaccacctttgttcttactgttaagttctttgtgctgcttccaaagatgatttacaagcagggatgttctaaatgggtctgtaccttagggtccggggtccagcccatatcctaggtcaaagcctacccacctggctcagctacctactgctttaaccaggctcatcctctctactccgctgtggttgccctccacggatgtgctctgagattctcttgctcagtggcaaggtggctgctctgctttcatttttaaaaaagcggaagttaaggtcatcatactaatactgcatcaactccaggaattaaaggaaagatctttattgctcaaccattttcttattggttcctactgacatattcatctcctttctgtgtctactggctgaaatgtttgtgtttgttcatctgactaacggtatggtttctgtatggttagacttgtaatgttttaaaatgtattttattactttggactggatgttcctctccagcgatacgaggtactttctaagctattaaggaagggtttgaatccctatgtgagataagataatggttgtttaaattttgcagaggtttttgttattgttactggttttgattttgggtttttttttgacctgtggggatattttgtgtttatgtgtccaaaaagtggggaggggaa
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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