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2024-11-01 07:54:16, GGRNA.v2 : RefSeq release 226 (Sep, 2024)

LOCUS       XM_030253390           15746 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus argonaute RISC catalytic subunit 3 (Ago3),
            transcript variant X8, mRNA.
ACCESSION   XM_030253390
VERSION     XM_030253390.2
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_030253390.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15746
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..15746
                     /gene="Ago3"
                     /gene_synonym="C130014L07Rik; Eif2c3"
                     /note="argonaute RISC catalytic subunit 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 8 mRNAs, 17 ESTs, 680 long SRA reads, 5 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 22 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:214150"
                     /db_xref="MGI:MGI:2446634"
     CDS             1247..3004
                     /gene="Ago3"
                     /gene_synonym="C130014L07Rik; Eif2c3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X4"
                     /protein_id="XP_030109250.1"
                     /db_xref="GeneID:214150"
                     /db_xref="MGI:MGI:2446634"
                     /translation="
MRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"
     misc_feature    <1247..1519
                     /gene="Ago3"
                     /gene_synonym="C130014L07Rik; Eif2c3"
                     /note="PAZ domain; Region: PAZ; pfam02170"
                     /db_xref="CDD:460472"
     misc_feature    1598..2875
                     /gene="Ago3"
                     /gene_synonym="C130014L07Rik; Eif2c3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2009..2011,2021..2023,2057..2068,2075..2077,
                     2099..2101,2108..2110,2120..2122,2132..2134)
                     /gene="Ago3"
                     /gene_synonym="C130014L07Rik; Eif2c3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2213..2215,2219..2221,2429..2431,2843..2845)
                     /gene="Ago3"
                     /gene_synonym="C130014L07Rik; Eif2c3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      
gtgacgcgagcgggcttccgggggcgaccgggaaaagcgagcggctgcggcggcggggcggctggcgggtcgggaagctgcacgcgtcagcatctgtgggcgacgcaagttccggacctggttccagcgtcctcactcaggactgtcgccgctcttacctcgctgcaggctgtctgtctctcccgactgtgcctcttgtgcccggagctttccgagggcgtccgctcctcgcctctgtggtggcacccttctctcgtgaagcactccccccagctccatgaatggaaatcggctccgcaggacccattggggcccagcccctattcatcgtgcccagaagacctgggtatggcactatgggcaaacccattaaactgttggctaactgttttcaagttgaaatcccaaagattgatgtctacctctatgaagttgacatcaaaccagacaagtgtcctcgaagagtgaacagagaagtagttgattcaatggttcagcattttaaagtgactatatttggagaccgtagaccagtttatgatggaaaaagaagcctttatacagccaatccacttcctgtggcaaccactggggtagatttagatgttacattacctggggaaggtggaaaagatcgacctttcaaggtgtcagtcaaatttgtgtctcgagtcagctggcacctactacatgaagcactggctggagggactttgcctgagccactggaattagacaagcctgtcagcactaaccccgtccatgccgttgacgtggtgctccgacatctgccctctatgaaatatacgcctgtggggcgttcctttttctcagctccagaaggatatgaccaccctctgggagggggcagggaagtatggtttggattccatcagtctgttcggcctgccatgtggaaaatgatgctaaatattgatgtttctgccactgccttttacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcacaacattgatgaacaacccagacccctgactgattctcatcgggtaaaattcactaaggagataaaagaaaatacaagatgtacagaacaaggattcagctgctgcccggagagcatggactcggtcttaacttcaactgctcaggggcccaaagaaatgactgaaaagttgactagaaagcattataaagttgatgttagagtgaaggtctgaaagttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacgagaaggcctgccagccaccaaacctttcctttacagctagaaaatggccaaactgtggagaggactgtggctcagtatttcagagaaaagtacacgctgcagctgaagtacccacaccttccctgcctgcaagtggggcaggagcagaagcatacatacctgccactagaagtctgtaatattgtggctgggcaaaggtgtatcaagaaactaacggacaatcagacttctacaatgataaaggcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcagtttaaagtgcgggatgaaatggcccatgtgacaggacgtgtacttccagcacctatgctccagtacggaggacggaaccggacagtagccacacccagccacggagtatgggacatgcgaggaaaacagttccacacaggagtcgaaatcaaaatgtgggctattgcttgctttgccacacagaggcagtgcagagaagaaatactaaaaggtttcacagaccagcttcggaagatttccaaggatgcagggatgcccatccagggtcagccatgcttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcaggactgcagctcattatcgtcatcctgcccgggaagacaccagtgtatgcggaagtgaaacgtgtgggagatacacttttgggtatggccacacagtgtgtacaagtcaagaatgtaataaaaacatctcctcaaactctttcaaacttgtgcctaaagatcaatgttaaacttggaggaatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatcttcctgggcgcagatgtcacacacccgcctgctggtgacggaaaaaagccctccattgctgctgttgtaggtagtatggatgcccatccaagcagatactgtgccacagtaagagttcagagaccccgacaggaaatcatccaggacttggcctccatggtccgggaactgctcatccaattttataaatcaacccgattcaaacctactcgtataatcttctatcgggatggtgtttcagaaggacagttcagacaggtattatattatgagctactggcaattcgagaagcctgtatcagtttggaaaaagactatcaacctggaataacctacattgttgttcagaagagacatcatacacggttgttctgtgctgataggacagaaagggttggaagaagcggcaacatcccagctggaaccacggtggataccgacattactcacccatatgaattcgacttttatctctgtagccatgctggaatacagggtaccagccgtccttcacactatcatgttttatgggatgacaacttctttactgcagatgaacttcagctgctcacttaccagctctgtcacacttacgtacgctgtacaagatctgtttctatccctgcaccagcatattacgctcacctggtggcattcagagccagatatcatcttgtggacaaggaacatgacagtgctgaaggaagccatgtttcaggacagagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtacttcgcttaacaagtccaagtttattctccgtgacaaagagatgaaaagtgaatcaacatacaatgtatgtttccaatggagtcaatttgctggggaggcctccagccatacagaagccagtactatgtagaggtcaggtccttatgttgatccaaggaaaatcgtttacactgtcaaagaacgcagcaccattgtacactagggagccagccgctgcttttttgcagtctcctgtagaagatgcatcaccattgtttattctcacttcttacagtctaacccttttaatgcctttacctcaagttgcttagcagcacaactatctctgcaaaaaagtaaagaaaaattgaatggtggtttaaaaacacacaattacacaaataatgattgttcagttatatgtgcagaaaaagtaatgtgcatctattcttgtaaaggagtctgtattttcaataccctcacattacttcatgtgcatatgtatctagatctaggttactgatgtatatgtgtctgtgtgtatatcttatagttcatttccctggagaactctttccttgtatccctccttaggccgcactcgtttcctttactgtctcccttgccttcagcatctatactttggtccctatagctacaagtgacattcctatgttcacacatatggttcacttgaaggaaggtttgacaaattagacttctggttttctttatgtccctattcctagctcctttcactcacacaggagtcctcagctcctgacgccatgtttgtgagcgtctgctcccttttgctctggatttaccacatgtgcactgtgtttggaaacagtggcaacctggggattcttttttgtagtgagtttgttaaagctgctctaaatacgaaaccttgtcggacatctttctgatcagtgcaaatgttctaaagcctctgtttgtatgagttatacctggaaatccctccaaaactcgataggatggaaaaaggaaggaattagggttggtttggtttgttttttgctagtttactcactgcccttataccttaatgtgattttctcacatataaatatatacatacacacacacacattgaagtatagctccctttgcctttatgttcattagaatagtgctttaataattataaactatataggctatatcttttctagaactagaatcgtgtttaagaatggagacagttttttgctctcttttagtgcaataagcagttttacaggaaagttctgtctgtcatcctcaccgtggatagcaggaagaacagacatccgtagtttaaagggaacaaagtaatacagccttaatttcagaaggagagcttcataattttcagttttaaagcaattccttaaaataattttagccaaaggagtaaaaccgatcaaaggcgcctcagctgtgaggtcagaagcatagttgaacttaagtttttaaaaatgacagtgaacagcttaagatttaaatattctttcttacttattgaagaattgtgcttctttgactaacaggaattgagaaaatacaggatgatttttttctatctttttaccagtataactttctctttaaaaataagatggcaatgatgaaggaaattaggactttggtcatttaaaattagtaaaatttccgaaatacagtgaaaactttgcaaaaacttagttttctccacttctttaatcaataaccttaataacgttggagctgtcaaagctgagtgtctcagtaatggcaggttcagggaactttgcactttgtaagtcatgaacattgcatgtgagttttctctgttgtccccaccctggctctgaggacagacactacagatgtttgtggaatgcactgtcggcctttcagaagccccaccccgccatgaacaggaatgcagttatgtcttcatttgctctctttagtccacattgtagccaatttactacatttcaatataaaatctgagccatgtcctacaggcatgaat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//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]