2024-11-01 08:18:46, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS XM_017313856 7047 bp mRNA linear ROD 07-FEB-2024 DEFINITION PREDICTED: Mus musculus Ros1 proto-oncogene (Ros1), transcript variant X3, mRNA. ACCESSION XM_017313856 VERSION XM_017313856.1 DBLINK BioProject: PRJNA169 KEYWORDS RefSeq. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.7) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_000001635.27-RS_2024_02 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.2 Annotation Method :: Best-placed RefSeq; Gnomon; RefSeqFE; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 02/01/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7047 /organism="Mus musculus" /mol_type="mRNA" /strain="C57BL/6J" /db_xref="taxon:10090" /chromosome="10" gene 1..7047 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Ros1 proto-oncogene; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 2 Proteins, and 100% coverage of the annotated genomic feature by RNAseq alignments, including 1 sample with support for all annotated introns" /db_xref="GeneID:19886" /db_xref="MGI:MGI:97999" CDS 442..6996 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /codon_start=1 /product="proto-oncogene tyrosine-protein kinase ROS isoform X3" /protein_id="XP_017169345.1" /db_xref="GeneID:19886" /db_xref="MGI:MGI:97999" /translation="
MKNICWLTLKLVKFVVLGCIIWISVAQSTVLSSCLTSCVTNLGRQLDSGTRYNLSEACIHGCQFWNSVDQETCALKCNDTYATICERESCEVGCSNAEGSYEEEVLESTELPTAPFASSIGSHGVTLRWNPANISGVKYIIQWKYAQLPGSWTFTETVSKLSYTVEPLHPFTEYIFRVVWIFTAQLHLYSPPSPSYRTHPYGVPETAPLILNMESWSPDTVEVSWAPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEGPEAESTVTTPSPSVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLWSDAIHHNITGISVYAQQQVVYFSEGTVIWMKGAANMSDVSDLRIFYQGSGLVSSISIDWLYQRMYFIMDKLVYVCELKNCSNLEEITPFSLIAPQKVVVDSYNGYLFYLLRDGIYRVNLPLPSGRDTKAVRIVESGTLKDFAVKPQSKRIIYFNDTMQLFMSTFLDGSAFHRVLPWVPLVTVKSFACENNDFLITDGKAIFQQDSLSFNEFIVGCDLSHIEEFGFGNLVIFGSSVQSYPLPGHPQEVSVLFGSREALIQWTPPALAIGASPSAWQNWTYEVKVYSQDILEITQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVGTTLVPATEPPFIMAVKEDGLWSKPLCSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTKGNVYVRPLNGMDISENYHIPSIVGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIVTHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWSGGDATITEFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTSLKPLPGNFSSTPKVIPDPVQESSFRIEGHTSSFQILWNEPPAVDWGIVFYSVEFSTHSKFLIIEQQSLPIFTVEGLEPYTLFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSSGRYTKKNEVVVEFRWNKPKHENGVLTKFEIFYHISKQSGTNRSTEDWMSASVIPPVMSFQLEAVSPEYTVAFQVRVFTSKGPGPFSDIVMSKTSEIKPCPYLISLLGNKIVFLDMDQNQVLWTFSLEGDVSTVGYTTDDEMGYFAQGDTLFLLNLRNHSSSKLFQDALVSDIRVIAVDWIARHLYFALKASQNGTQIFNVDLEHKVKSPREVKTCKAHTTIISFSIYPLLSRLYWTEVSDLGHQMFYCNISNHTSQHVLQPKASNQHGRSQCSCNVTESELSGAMTVDTSDPDRPWIYFTKRQEIWAMDLEGCQCWKVIMVPTIPAGKRIISLTVDGEFIYWIMKTKDDAQIYQAKKGSGAILSQVKASRSKHILAYSSALQPFPDKAYLSLASDMVEATILYATNTSLTLKLPPVKTNLTWHGITHPTSTYLIYYMEANRANSSDRRHKMLESQENVARIEGLQPFSMYMIQIAVKNYYSEPLEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHKPNGPKESVRYQLVMSYLAPIPETPLRQGEFPSAKLSLLITKLSGGQLYVMKVLACHPEEMWCTESHPVSVNMFDTPEKPSALVPENTSLQLDWKARSNVNLTGFWFELQKWKYNEFYHVKASCSQGPVYVCNITDLQPYTSYNIRVVVVYTTGENSSSIPESFKTKAGVPSKPGIPKLLEGSKNSIQWEKAEDNGSRLMYYTLEVRKGISNDSQNQSSRWKVVFNGSCSSICTWRSKNLKGTFQFRAVAANEIGLGEYSEISEDITLVEDGVWITETSFILTIIVGIFLVATVPLTFVWHRSLKSHKASKEGLSVLNDNDKELAELRGLAAGVGLANACYAVHTVPTQEEIENLPAFPREKLSLRLLLGSGAFGEVYEGTAIDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYKNDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNCPDDL"
misc_feature <739..>1329 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain [General function prediction only]; Region: FN3; COG3401" /db_xref="CDD:442628" misc_feature 2143..2433 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(2143..2145,2350..2352,2395..2397) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature order(2398..2403,2407..2412) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 3550..3870 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(3550..3552,3787..3789,3832..3834) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature order(3835..3840,3844..3849) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature <4945..>5700 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain [General function prediction only]; Region: FN3; COG3401" /db_xref="CDD:442628" misc_feature 5392..5667 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(5632..5637,5641..5646) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 5680..5961 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(5935..5940,5944..5949) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 6286..6993 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-specific and tyrosine-specific protein kinases. It also includes RIO kinases, which are atypical serine protein kinases, aminoglycoside phosphotransferases; Region: Protein Kinases, catalytic domain; cl21453" /db_xref="CDD:473864" ORIGIN
catagtcaaaacccaatttcctgcatagctcagtcaacctcaaagaagtgcggtggctgaccgacctaagtgtcctgtgtcaggattgtgtggcctggctcgctggaaagcaatctaagtttctcctgtttatttagcatgtgtagagctcttcctggatctaacttttagccagggaatgtcttttgttatgggagcaaaaggaagctaaactataaaatagccttgctgcgatgttctgggctatctaagatccaaaggtctaaactaatccaaaggcctcaatattctttttaaagagagaatgatattctaacattgcgaaagaaaacagaaaacctacttgtcacacttgcaactgaagtatgaagcctaaagagttcttaaagcaaggtggagctatgaggaccccagctgtgtaggaagccagccctcctgaggatgaagaacatctgctggctcaccctgaaacttgtgaagtttgtggtccttgggtgcatcatatggatttctgtggcacagagtacagttctgagcagctgcctaacgtcctgtgtaactaacctgggcaggcagcttgacagtggcacacggtacaatctgagtgaggcgtgcatccatggatgtcagttttggaactctgtagatcaggaaacgtgtgctttaaagtgtaatgacacctacgccaccatttgtgagagggagtcctgtgaggtcggctgcagcaatgcggagggtagctacgaagaggaagtgctggaaagcacagaacttcctacagcaccctttgcatcttccattggaagtcatggtgtgacattacgctggaaccctgccaacatctctggagtcaaatacataattcaatggaaatatgcccaacttccaggaagctggactttcacggagaccgtgtccaagctctcatacacggtggaacccctgcatccattcacagaatatatttttcgagtggtttggatcttcacagcccaactgcatctttattccccaccaagtcccagttacaggactcatccttatggagttccagaaactgcacctctcatcctgaacatggaaagctggagccctgatactgtggaggtcagctgggctccacctcatttcccaggtggacctattttgggttataatttaaggctcatcagtaaaaatcaaaaattagattcagggacacagagaaccagtttccagttttattctactctaccaaacaccacctacaggttttctatcgcagcagtcaatgaagttggtgaggggccagaagcagaatctacagttaccactccatccccatcagttcaagaagaagaacaatggctctttttatccagaaaaacttctctaagaaagaggtctttgaagtacttagtagatgaagcacattgcctttggtcagatgctatacaccataatattacaggaatatcagtctatgctcagcagcaagtggtttatttttcagaaggaactgtcatctggatgaagggggctgccaacatgtctgatgtgtctgacctgagaattttttaccaaggctcaggtctagtgtcttctatctccatagactggctgtaccaaaggatgtatttcatcatggataaactggtatatgtctgtgaattaaagaattgctcaaatttagaggaaatcactcccttctctcttattgcacctcagaaagttgtggttgactcctacaatgggtacctcttttatctcctgagagacggcatctacagagtcaatctccctttgccatctggcagggacaccaaagctgtgcgtattgtggagagtggcacattaaaggactttgcagtaaagccccaatccaagcgaatcatttacttcaatgacaccatgcaactcttcatgtcaacgtttctggatggctctgccttccaccgggtcctgccttgggtcccccttgtgactgtgaagagctttgcttgtgaaaacaatgacttcctcatcacagatggcaaggccatttttcagcaggactccctgtctttcaatgaattcatcgtgggatgtgacctgagtcacatagaagagtttgggtttggtaacttggtcatctttggctcctctgtccagtcataccctctgccaggacatccacaggaggtctcagtgctgtttggttctcgagaggcccttattcagtggacgcctcctgctctcgccataggagccagtccttccgcctggcagaactggacttatgaagtcaaagtttattcccaggacatccttgaaatcactcaagttttctcgaacataagcgggaccatgcttaatgtacccgaactgcagagttctacaaagtacactgtctctgtgagagcaagttctcctaaaggcccaggcccctggtcagcaccatcagtgggtaccaccttggtaccagctactgaaccaccattcatcatggctgtgaaagaagatgggctctggagcaaaccactctgtagttttggtccaggagaattcctgtcctctgatgtaggaaacgtgtcagatatggattggtacaacaacagcctctactacagtgacacaaaaggcaacgtttatgtgcggcctctgaatgggatggatatctcagagaattatcacatacccagcattgtaggagctggggctttggcctttgaatggctgggtcactttctctactgggctgggaagacatatgtgatccaaaggcagtctgtgttgacgggacacacggacattgtgactcatgtgaagctgttggtgaatgacatggctgtggattcagttggtggctatctctattggacaacactctactcagttgaaagcaccagactcaatggagaaagttctcttgtactacaggctcagccctggctctctggaaaaaaggttattgctctaacactagacctcagtgatgggctcctgtattggctggtgcaggacaatcagtgtattcatctgtacacagctgttcttcgaggatggagtggtggggatgctaccatcacagagtttgcagcctggagtacttctgaaatctcccagaatgcactgatgtactacagtggtagactcttctggatcaatggatttaggatcattacagcacaggaaataggtcagagaaccagtgtgtctgtttcggagccagcgaaattcaatcagttcacaattatacagacatctctcaagcctctgccaggaaacttttcctctactcccaaggttatcccagatcctgttcaggagtcttcatttcgaattgaaggacacacttcaagtttccaaatcctgtggaatgagccccctgcggtggactggggcatcgttttctacagtgtggaatttagcactcattccaagttcctgattattgaacaacagtctttacctatttttactgtggaaggactggagccctataccttatttaatctttctgtcactccttatacctactggggaaagggccaaaaaacatctctatcatttcgtgcacctgaatcagttccatcagcaccagaaaaccccagaatatttatattgtcaagcggaagatacaccaagaagaatgaagttgtggtagagttcaggtggaataaacctaagcatgaaaatggagtgctaaccaaatttgaaatcttctatcacatatctaaacaaagtggcacaaatagatcaactgaagactggatgtctgccagtgttatacccccagtgatgtcttttcaacttgaggctgtgagtcctgagtatactgttgccttccaggttagagtcttcacatccaaagggccagggccattttctgatatagtgatgtctaaaacatcagaaatcaagccatgtccgtatctcatatctcttctcggcaataagatcgtgtttctagacatggatcaaaatcaagttttgtggacattttccctggagggagacgtcagcacagtggggtacacaacagacgatgaaatggggtatttcgctcaaggagacacgctcttccttctgaatttgcgtaatcattccagttccaagcttttccaggatgcactggtttctgacattagagttattgctgttgattggattgcaaggcacctctactttgctctgaaagcatcacaaaacggaacacagatattcaatgttgaccttgaacacaaggtgaaatcccccagggaggtgaagacttgcaaagcacatacaacaataatttctttctctatatatcccctcttgagtcgcttgtattggacagaagtttcagatctgggccatcagatgttctactgcaatattagcaatcacacctcgcaacatgttctacaacccaaggcttcaaaccaacatggaaggagtcaatgttcttgtaatgtgacagaatctgagttaagtggggcaatgactgtggatacctctgacccagacagaccatggatatactttaccaaaaggcaagagatctgggccatggatctggaaggatgtcagtgttggaaagtcatcatggtacctactatccctgcaggaaaaagaatcattagcttaacagtggatggggagtttatatattggatcatgaaaacaaaggatgatgcccaaatttatcaagcaaagaagggaagcggggccatcctttcccaagtgaaggcctccaggagtaagcatatcttggcttacagttctgctctgcagccttttccagataaagcatatctgtctctagcttcagatatggtagaagcaactatattatatgccaccaacaccagcctcacactcaaattacctccagtcaagacaaacctcacgtggcatggtattacccaccccacgtcaacatacctgatttactatatggaagctaatagggcaaacagctctgacaggagacacaaaatgctggaatcacaggagaatgtagcccggattgaaggtctgcagccattttcaatgtacatgattcagatagctgtgaagaactattattcagagcctttagaacatttacctcttggaaaagagattcaaggacaaactaaaagtggagtgcctggggcagtttgtcatatcaacgcaactgtgttgtcggacaccagtctccatgtattctggacagaatcccataagccaaacggaccaaaagagtcagtccgctatcagctggttatgtcatacctggctcccattcctgagactcctctaagacagggtgaatttccaagtgccaagctttctctgctcatcactaaactatctggtggacagctctatgtgatgaaggttctggcgtgccaccctgaggaaatgtggtgtactgagagtcatcctgtcagtgtcaacatgtttgacacaccagagaaaccctctgccttggttccagagaacactagtctgcagttagattggaaggctcgatcaaacgttaacctcaccggattttggtttgaactccagaagtggaaatataatgagttttaccatgtcaaagcttcatgcagccaaggtccagtttatgtctgtaacatcacagatctacaaccttacacctcctataacattcgagtggtggtggtctatacgacaggagaaaatagctcctccattccagagagtttcaagacaaaagccggagtcccaagcaaaccaggtattcctaaattactagaagggagtaaaaattccatccagtgggaaaaagctgaagataatgggagcagattgatgtactacacccttgaggtcagaaaaggcatttcaaatgactcacagaaccagagttcaaggtggaaggtggtgtttaatgggtcctgcagtagcatttgcacatggagatcaaaaaacctaaaaggaacatttcagttcagagcagttgctgcaaatgaaattggacttggagaatatagtgaaatcagtgaagacattacattagtggaagatggtgtttggataacagaaacaagttttatacttactatcatagttgggatatttctggttgctacagtcccactgacctttgtctggcatagaagcttgaaaagtcacaaagcttccaaggaaggcctctcggttctcaacgacaacgacaaagagttggctgagcttcgaggtctggcggctggagtgggactggccaatgcctgctacgcagtacatactgttccaacccaagaagagattgaaaatcttcctgccttccctcgggagaagctgagcctgcgtcttttgttgggaagtggagcttttggagaagtgtatgaaggcacagctatagacatcctaggcgtgggaagtggagaaatcaaagtggcagtgaagaccttgaagaaaggttcaacagaccaggagaagattgagttcctgaaggaggcgcacctgatgagcaagtttaatcaccccaacattctgaagcagctgggagtctgtctgttaggcgaaccccagtacattattctggaactgatggaagggggagaccttctaagctatctgcgcaaagctcgggggacaacgtttcatggtccttcactcaccttgcttgaccttgtagagctgtgtgtagatatttcaaaaggctgcgtctacttggagcagatgcacttcattcacagggatctggcagctcggaattgccttgtatcagtgaaagactacaccagtcctcgggtagtcaagattggtgactttggattggcaagagaaatctataaaaatgattattatagaaagagaggggaaggcctgcttcctgttcggtggatggctcctgaaaacttgatggacggaatcttcacttctcagtctgatgtatggtcctttggaattttggtgtgggagattttaactctcggtcatcaaccttatccagcgcattccaaccttgatgttttaaactatgtgcaagcaggagggagactggagccaccaagaaattgtcctgatgatctgtgaagatgatgaaatggtcactttgaactcagatgacacgatgccagttgcctt
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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