2024-11-01 08:37:41, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS XM_011240478 3006 bp mRNA linear ROD 07-FEB-2024 DEFINITION PREDICTED: Mus musculus argonaute RISC catalytic subunit 3 (Ago3), transcript variant X1, mRNA. ACCESSION XM_011240478 VERSION XM_011240478.4 DBLINK BioProject: PRJNA169 KEYWORDS RefSeq. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 21, 2020 this sequence version replaced XM_011240478.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_000001635.27-RS_2024_02 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.2 Annotation Method :: Best-placed RefSeq; Gnomon; RefSeqFE; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 02/01/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3006 /organism="Mus musculus" /mol_type="mRNA" /strain="C57BL/6J" /db_xref="taxon:10090" /chromosome="4" gene 1..3006 /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /note="argonaute RISC catalytic subunit 3; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 15 ESTs, 138 long SRA reads, 1 Protein, and 100% coverage of the annotated genomic feature by RNAseq alignments, including 14 samples with support for all annotated introns" /db_xref="GeneID:214150" /db_xref="MGI:MGI:2446634" CDS 282..2804 /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /codon_start=1 /product="protein argonaute-3 isoform X1" /protein_id="XP_011238780.1" /db_xref="GeneID:214150" /db_xref="MGI:MGI:2446634" /translation="
MEIGSAGPIGAQPLFIVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSVKFVSRVSWHLLHEALAGGTLPEPLELDKPVSTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSALPDGSVSRRLAKQA"
misc_feature 498..782 /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 810..962 /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 963..1325 /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1119..1121,1164..1166,1206..1208,1218..1220, 1272..1274,1293..1295,1299..1301) /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_feature 1458..2735 /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(1869..1871,1881..1883,1917..1928,1935..1937, 1959..1961,1968..1970,1980..1982,1992..1994) /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(2073..2075,2079..2081,2289..2291,2703..2705) /gene="Ago3" /gene_synonym="C130014L07Rik; Eif2c3" /note="active site" /db_xref="CDD:240015" ORIGIN
gtgacgcgagcgggcttccgggggcgaccgggaaaagcgagcggctgcggcggcggggcggctggcgggtcgggaagctgcacgcgtcagcatctgtgggcgacgcaagttccggacctggttccagcgtcctcactcaggactgtcgccgctcttacctcgctgcaggctgtctgtctctcccgactgtgcctcttgtgcccggagctttccgagggcgtccgctcctcgcctctgtggtggcacccttctctcgtgaagcactccccccagctccatgaatggaaatcggctccgcaggacccattggggcccagcccctattcatcgtgcccagaagacctgggtatggcactatgggcaaacccattaaactgttggctaactgttttcaagttgaaatcccaaagattgatgtctacctctatgaagttgacatcaaaccagacaagtgtcctcgaagagtgaacagagaagtagttgattcaatggttcagcattttaaagtgactatatttggagaccgtagaccagtttatgatggaaaaagaagcctttatacagccaatccacttcctgtggcaaccactggggtagatttagatgttacattacctggggaaggtggaaaagatcgacctttcaaggtgtcagtcaaatttgtgtctcgagtcagctggcacctactacatgaagcactggctggagggactttgcctgagccactggaattagacaagcctgtcagcactaaccccgtccatgccgttgacgtggtgctccgacatctgccctctatgaaatatacgcctgtggggcgttcctttttctcagctccagaaggatatgaccaccctctgggagggggcagggaagtatggtttggattccatcagtctgttcggcctgccatgtggaaaatgatgctaaatattgatgtttctgccactgccttttacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcacaacattgatgaacaacccagacccctgactgattctcatcgggtaaaattcactaaggagataaaaggtctgaaagttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacgagaaggcctgccagccaccaaacctttcctttacagctagaaaatggccaaactgtggagaggactgtggctcagtatttcagagaaaagtacacgctgcagctgaagtacccacaccttccctgcctgcaagtggggcaggagcagaagcatacatacctgccactagaagtctgtaatattgtggctgggcaaaggtgtatcaagaaactaacggacaatcagacttctacaatgataaaggcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcagtttaaagtgcgggatgaaatggcccatgtgacaggacgtgtacttccagcacctatgctccagtacggaggacggaaccggacagtagccacacccagccacggagtatgggacatgcgaggaaaacagttccacacaggagtcgaaatcaaaatgtgggctattgcttgctttgccacacagaggcagtgcagagaagaaatactaaaaggtttcacagaccagcttcggaagatttccaaggatgcagggatgcccatccagggtcagccatgcttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcaggactgcagctcattatcgtcatcctgcccgggaagacaccagtgtatgcggaagtgaaacgtgtgggagatacacttttgggtatggccacacagtgtgtacaagtcaagaatgtaataaaaacatctcctcaaactctttcaaacttgtgcctaaagatcaatgttaaacttggaggaatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatcttcctgggcgcagatgtcacacacccgcctgctggtgacggaaaaaagccctccattgctgctgttgtaggtagtatggatgcccatccaagcagatactgtgccacagtaagagttcagagaccccgacaggaaatcatccaggacttggcctccatggtccgggaactgctcatccaattttataaatcaacccgattcaaacctactcgtataatcttctatcgggatggtgtttcagaaggacagttcagacaggtattatattatgagctactggcaattcgagaagcctgtatcagtttggaaaaagactatcaacctggaataacctacattgttgttcagaagagacatcatacacggttgttctgtgctgataggacagaaagggttggaagaagcggcaacatcccagctggaaccacggtggataccgacattactcacccatatgaattcgacttttatctctgtagccatgctggaatacagggtaccagccgtccttcacactatcatgttttatgggatgacaacttctttactgcagatgaacttcagctgctcacttaccagctctgtcacacttacgtacgctgtacaagatctgtttctatccctgcaccagcatattacgctcacctggtggcattcagagccagatatcatcttgtggacaaggaacatgacagtgccctgccagatggctcagtcagtagaagacttgccaaacaagcctgacagcctgacctaggctcagtcatcagaactcaggatggaactagagaactgactcctgatggttgtcctcagacctctctgtgggcaccatggcataaatggaccaacaaacacaagacaacaacagcaattgtaataataaataacttttcatgagcatgacttcatttataataaagataattcaccattctgcatcctg
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]