2024-11-01 08:10:38, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS XM_006519329 4994 bp mRNA linear ROD 07-FEB-2024 DEFINITION PREDICTED: Mus musculus piwi-like RNA-mediated gene silencing 2 (Piwil2), transcript variant X1, mRNA. ACCESSION XM_006519329 VERSION XM_006519329.4 DBLINK BioProject: PRJNA169 KEYWORDS RefSeq. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 21, 2020 this sequence version replaced XM_006519329.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_000001635.27-RS_2024_02 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.2 Annotation Method :: Best-placed RefSeq; Gnomon; RefSeqFE; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 02/01/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..4994 /organism="Mus musculus" /mol_type="mRNA" /strain="C57BL/6J" /db_xref="taxon:10090" /chromosome="14" gene 1..4994 /gene="Piwil2" /gene_synonym="mili; Piwil1l" /note="piwi-like RNA-mediated gene silencing 2; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 2 mRNAs, 8 ESTs, 39 long SRA reads, 10 Proteins, and 99% coverage of the annotated genomic feature by RNAseq alignments, including 2 samples with support for all annotated introns" /db_xref="GeneID:57746" /db_xref="MGI:MGI:1930036" CDS 276..3191 /gene="Piwil2" /gene_synonym="mili; Piwil1l" /codon_start=1 /product="piwi-like protein 2 isoform X1" /protein_id="XP_006519392.1" /db_xref="GeneID:57746" /db_xref="MGI:MGI:1930036" /translation="
MDPVRPLFRGPTPVHPSQCVRMPGCWPQAPRPLEPAWGRAGPAGRGLVFRKPEDSSPPLQPVQKDSVGLVSMFRGMGLDTAFRPPSKREVPPLGRGVLGRGLSANMVRKDREEPRSSLPDPSVLAAGDSKLAEASVGWSRMLGRGSSEVSLLPLGRAASSIGRGMDKPPSAFGLTARDPPRLPQPPALSPTSLHSADPPPVLTMERKEKELLVKQGSKGTPQSLGLNLIKIQCHNEAVYQYHVTFSPSVECKSMRFGMLKDHQSVTGNVTAFDGSILYLPVKLQQVVELKSQRKTDDAEISIKIQLTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDSVLDVMHAIYQQNKEHFQDECSKLLVGSIVITRYNNRTYRIDDVDWNKTPKDSFVMSDGKEITFLEYYSKNYGITVKEDDQPLLIHRPSERQNNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLTQQINLSPKQHHGALECLLQRISQNETASNELTRWGLSLHKDVHKIEGRLLPMERINLRNTSFVTSEDLNWVKEVTRDASILTIPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRISPPAWVELKDDRIETYIRTIQSLLGVEGKIQMVVCIIMGTRDDLYGAIKKLCCVQSPVPSQVINVRTIGQPTRLRSVAQKILLQMNCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKYYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFDNYHPKMVVFVVQKKISTNLYLAAPDHFVTPSPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYICVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGQILHHEPAIQLCGNLFFL"
misc_feature <279..875 /gene="Piwil2" /gene_synonym="mili; Piwil1l" /note="large tegument protein UL36; Provisional; Region: PHA03247" /db_xref="CDD:223021" misc_feature 1284..1427 /gene="Piwil2" /gene_synonym="mili; Piwil1l" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1428..1781 /gene="Piwil2" /gene_synonym="mili; Piwil1l" /note="PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the...; Region: PAZ_piwi_like; cd02845" /db_xref="CDD:239211" misc_feature order(1560..1562,1599..1601,1623..1625,1635..1637, 1689..1691,1740..1742,1746..1748) /gene="Piwil2" /gene_synonym="mili; Piwil1l" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239211" misc_feature 1803..3137 /gene="Piwil2" /gene_synonym="mili; Piwil1l" /note="PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of related...; Region: Piwi_piwi-like_Euk; cd04658" /db_xref="CDD:240016" misc_feature order(2310..2312,2322..2324,2358..2369,2376..2378, 2406..2408,2415..2417,2427..2429,2439..2441) /gene="Piwil2" /gene_synonym="mili; Piwil1l" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240016" misc_feature order(2502..2504,2508..2510,2712..2714,3111..3113) /gene="Piwil2" /gene_synonym="mili; Piwil1l" /note="active site" /db_xref="CDD:240016" ORIGIN
aaggcgtgccacctgtttgagagcaacctccacatagctagactgcgtgaaagggtgagccaatgaggtgagggactcttttgagtggtaggttgtttggccaatgagctgagcccttgggctagggatccggaaatcaggacctcgggcacgaggctcattccaagaggcagatgaggctgtgttctgcctagacagggggcttcaggaccctgacgaccctaggccagataaggaattggaacagaaccaacagtcgtttctacagcctctcaatggatcctgtcaggccgttgttcagggggcccaccccagtccacccatctcagtgtgtgcggatgccaggctgttggcctcaagctcctagacctttggaaccagcttggggtagggcaggacctgcaggcagaggccttgtgtttagaaaaccagaagactccagcccaccactccagccagtacaaaaggattctgtaggtttggtgtccatgttccgtggcatgggtcttgacacagcattccggcctccttcaaaacgagaagtgcctcctttaggcagaggagttctaggtcgaggcttgtctgctaacatggtccgcaaggacagagaagaaccccgttcctctttgcctgatccttcggtgctggcagctggggacagcaaactggcagaggcttctgttggttggagtagaatgctgggaagaggtagttctgaggtctctctgttaccactgggacgagcagccagtagtataggcagaggaatggacaaacctcccagtgcctttggcctcacagctcgggatcccccacggctgccacagcctccagctctgtctccaacttcactgcactctgccgatccccctccggtcctgactatggaacgaaaggaaaaagagcttttggtcaagcaaggatcaaaaggaactcctcagtctttgggactgaacctcatcaaaatccagtgtcataacgaagcagtttatcagtaccatgtgactttcagccccagtgtggaatgcaaaagcatgaggtttggcatgttgaaggaccaccagtctgtcactggaaacgtcactgcttttgatggctctattctttatcttcctgttaagcttcaacaagttgttgagttaaaaagtcagaggaaaactgacgatgccgagatcagtatcaagattcagctgacaaagatcctggagccgtgttctgacctgtgcatccccttctacaatgttgtcttccggcgggtaatgaaacttctggatatgaagcttgtggggagaaacttctatgaccctacaagtgccatggtactgcagcaacacagattgcagatctggcctggctatgcggctagtatccggaggacagacgggggtctcttcctgctcgctgatgtctctcataaggtcattcggaacgactctgtgctggatgtcatgcatgctatctaccagcagaacaaggagcacttccaggacgagtgcagcaagcttctggttggcagcattgtcatcacgcgctacaacaatcgtacctaccgaatcgatgatgtggactggaacaagacccctaaagacagctttgtcatgtcggacgggaaggaaatcacattcctggaatactacagcaaaaactatgggatcacagtcaaggaagatgaccagccgctgctgatccaccggcccagtgagagacagaataaccatggcatgttgctgaagggcgagatcctgctgctgcccgagctctccttcatgacggggatccctgagaagatgaagaaggacttcagggccatgaaggacttgactcagcagattaacctgagccccaagcagcaccacggtgctttggaatgcctgctgcagagaatttcacaaaacgagacagccagcaatgagctgacccgctgggggctcagtctgcataaagatgtccacaagattgaaggtcggcttctgccaatggagaggatcaacttaaggaacacttcatttgtcacatcggaggacctgaactgggttaaggaagtgaccagagatgcttccattctaactattcccatgcatttctgggcactcttttatccaaagagagcaatggaccaagccagagaactggttaacatgttggaaaagattgccgggcccattggcatgcgcataagccccccagcctgggttgagctgaaggatgaccgaatagagacctatatcaggaccattcagtccttactgggagttgaggggaagatacaaatggtcgtttgcatcatcatgggcacacgtgatgatctctatggagccatcaagaagctgtgctgcgtgcagtccccagtgccctcacaggtcatcaatgtccgaaccattggtcagcccaccaggcttcggagcgtggctcagaaaattttacttcagatgaactgtaaactgggtggtgagctctggggagtggatattccgctgaaacaactaatggtgattggaatggatgtgtaccatgaccccagcagaggcatgcgctctgtggtcggcttcgtggccagcataaatctcacactcaccaaatggtactcgagggtggtgttccagatgccacatcaggagattgtggacagcctgaagctctgcctggtgggttccttgaaaaagtattatgaggtgaaccattgtctcccagagaaaattgtggtgtaccgagatggagtgtctgatggccagctaaagacagttgccaactacgagatccctcagctgcagaagtgttttgaagcctttgataactaccaccccaagatggtggtgtttgtagttcagaagaaaatcagcaccaatctgtaccttgctgctcctgatcacttcgtaaccccctcccccgggactgtggttgatcataccataaccagctgtgagtgggtggatttctaccttcttgcccatcatgtgcgacagggctgtggcatacctacacactacatctgtgttctgaacactgcaaatctgagccctgatcacatgcagaggttgactttcaaactatgccacatgtactggaattggcctggtaccatccgagttccagctccttgcaagtatgcccacaagctagctttcctgtccggacagattttgcatcatgagccagccatccagctgtgtgggaacctgttcttcctgtaactgggaacttggacaccggctgcaaggagcaactggactcagctcagctcctccttacagaatcaacagaaatggcagtggaattttatgtttgcattttctctttctccatccttgtagaattagatttctgttcttcttttaaccctgatatcatagtagggtgttgtggtgcatgccttttatcccagcacttgggagactgaagcaggagtatctttagttcaaggccagcctagactacatggtgagttctaggctagccaagattacagagtgagaccctgtctcaaaaaacaaaaacaaaccactgtcccctcaaagcccacaacaaaaccaaagcctggggtcaaggaagcaagtttgtaggtagccgctggctgcccgctgccttcatggagtgtgtgccgtcagcgctgcttctcctcagccgagcgtggagcttcggacagggcagtgatgacatgttcttagcatgtcaaatccccctaccaaataagtcaagcaaggaaaaaatagcccccaaggcagcctgagcatcagttcctagaggttatgcctacagaaccatcctatttctggtggcagaagtgacatgaagtcattgcagacatcttaaaggagagttactgtgcagctgtctacatgtgtgaaagacatgtagaaaaaccagcgtagggtacagtcgggcgtatgtgcccacctgacccagggctgtgagtctgacttcccgagagtctggctagagctgcttttctggtccttttggttatttgcaaccatcatcagattgctttcctgcagcccgactgatacacgcatgtgcgcacgcacacacttttgttctttgtgactaatcttgaataaattcaattagaacacatggaaaggattcagcagacctaggaacatttggggtggagtgtagtttttctgcaaaagtctgtaaatgagattacgcaagagtctcttccagctgtgggctggtgttgcttggaaaatttcaaaatcccaaagtttcaggcttcccaaagttggcttggaaaaatgtgatagtctcacctgagtctagacatgtaggaaattttcctagggcctctgggcttcagtatttgggggaagcactggttttctgtgttatttttttccttctgtttcagaatcttcaagtttcttcaggcttcagtgggccatccctttactgggctctaaaagctaattttacttaaccttttcaaatgtgtatgtatctatttatgttttggtgtggtggatggatggtaggggactgagcagaaatagtcattttaaataacagtgtgctaggagagcctcagtgtgaagtcctgaggagcagcgggggctgtgggagtcagtgtcagccctcactcagacaggccaagcctgggctcgaagacaacattgtccagggaagcctttagtttgctatagcacccagaggttggcgaggaataagggttagggtcctcaaatacacccatggcttttggagtctatgaccaaggccaggctgagacctgaaatgtaaaagccatagaattaaacagaacagactgaaaaacgagtcttaagttccactttctggatttctctggaagtcttttgaatttgtctgtagaagttgctgttcctagcactccttttctctttaggtagaacagatacttgaccataatgccagaatgtactttctctgccttggtttttctatgccttgtttttcagtttcagggccaaacaattgggccctgtggtgtaaaataaaaacaatgtatgtgtata
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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