LOCUS       XM_006503482            2599 bp    mRNA    linear   ROD 10-APR-2023
DEFINITION  PREDICTED: Mus musculus argonaute RISC catalytic subunit 4 (Ago4),
            transcript variant X3, mRNA.
ACCESSION   XM_006503482
VERSION     XM_006503482.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 8, 2019 this sequence version replaced XM_006503482.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2023_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/05/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2599
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..2599
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /note="argonaute RISC catalytic subunit 4; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 ESTs, 41 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     16 samples with support for all annotated introns"
                     /db_xref="GeneID:76850"
                     /db_xref="MGI:MGI:1924100"
     CDS             384..2504
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /codon_start=1
                     /product="protein argonaute-4 isoform X3"
                     /protein_id="XP_006503545.1"
                     /db_xref="GeneID:76850"
                     /db_xref="MGI:MGI:1924100"
                     /translation="

MEALGPGPPASLFQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRIDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKHPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPSQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKMNAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEITQELLYSQEVVQDLTSMARELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVLPSAQCHPTSTLTERPPSCYWRPET"

     misc_feature    426..2429
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /note="protein argonaute; Provisional; Region: PLN03202"
                     /db_xref="CDD:215631"
     misc_feature    1533..>2429
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /note="PIWI domain. Domain found in proteins involved in
                     RNA silencing. RNA silencing refers to a group of related
                     gene-silencing mechanisms mediated by short RNA molecules,
                     including siRNAs, miRNAs, and heterochromatin-related
                     guide RNAs. The central component...; Region: Piwi-like;
                     cl00628"
                     /db_xref="CDD:412485"
     misc_feature    order(1944..1946,1956..1958,1992..2003,2010..2012,
                     2034..2036,2043..2045,2055..2057,2067..2069)
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:239208"
ORIGIN      

cccctgcctcggtcaggctcgctggaccccgcgcgtgcggggccgcgcacgcccccttcgctagccgggacccgggaccgcaggcgcctggcgcccccgccccgcccggcgggcgcgcgccgcctcccgctcccgttccagctggcggcggcggcggcagcggccgggattgtttttgttgtcgctgaggccggaagagccgtgacagagtcgggtccctgtccccggactgggcgccgccgccgccccctgcccgcccccggcccgcgtcttcgcggcgccgcttcagcgccaatattccagagagcaagcgttacgcggctccggcggggcccggagcgggaggcgctggggaccggagcgaggcggcccccgtcgccgccatggaggcgctgggacccggacctccagccagcctcttccagccacctcggcgtcctggccttggaaccgttgggaaaccaattcgactgttagccaatcattttcaggttcagatccctaaaatagatgtgtatcactatgatgtggatattaaaccagaaaaacggcctcgtagagtcaacagggaggtggtagacactatggtgcggcacttcaagatgcagatatttggagatcggcagcctggctacgatggcaaaagaaacatgtacacggcacacccactgccaatcggacgggataggattgatatggaggtgaccctcccaggtgagggtaaagaccaaactttcaaagtgtctgtgcagtgggtgtcagttgtgagccttcagctgcttttagaagctttagcaggacacctgaatgaagtcccagatgactcagtacaagcacttgatgtgattacaaggcatctcccctctatgaggtacactccagtaggccggtcttttttctcacctcctgaaggttattaccaccctctgggagggggcagagaggtttggtttggctttcatcagtctgtgagacctgccatgtggaatatgatgctcaatattgatgtatctgcaactgctttctaccgggctcaacctatcattgagttcatgtgtgaggttttagacattcagaacatcaatgagcagacaaaacctctaacagactcccagcgtgtcaagtttaccaaagaaattaggggtcttaaggttgaggtgactcactgtggacagatgaaacgaaaatatcgagtttgtaatgtgacaagacggccagccagtcatcaaaccttccctttgcagctagagaatggccaagctatggaatgtacagtggctcagtattttaagcagaagtatagtctgcagctgaaacacccccaccttccctgccttcaagtggggcaagagcaaaagcatacctacctaccacttgaggtctgtaatatagtggcaggacagagatgtataaagaagctcacagacaatcagacatccaccatgatcaaagccacggcaagatctgctcctgacagacaggaggaaatcagtagactggtgaagagcaacagcatggtgggtggacctgacccatacctgaaggaatttgggattgttgtgcacaacgagatgacagagctcacaggcagggtgcttccggctccaatgctgcagtatggaggccggaataaaacagtagccacacccagccagggtgtctgggacatgcgaggaaaacagttttatgctggcattgaaattaaagtatgggcagtggcttgttttgcgcctcagaaacaatgtagggaagatttgctaaagagtttcactgaccaacttcgtaaaatctccaaggatgcagggatgcccatccagggtcagccatgtttctgcaagtatgctcaaggtgcagacagcgtggagcccatgtttaaacatctgaaaatgacatatgtgggcctgcagctaatagtggtgattttgcctgggaagacaccagtatatgcggaggtgaagcgtgttggagatacccttctaggtatggccacacagtgtgtccaggtcaaaaacgttgtgaagacctcgccccagaccctttccaacctttgcctgaagatgaacgcaaagctgggagggattaacaatgtgcttgtgcctcaccaaaggccctcagtgttccagcagcctgtcatctttctgggagcagatgtcactcatccgcctgctggggacgggaagaagccttctattgcagccgtggtgggcagcatggacggccatcccagccggtactgtgccacagtccgggtacagacatctcgacaggagatcacccaggagctcctctacagccaggaggtcgtgcaggacctgacgagcatggctcgggagctgctgattcaattctataagtccacgcgcttcaagcccacacgcatcatctactaccgcggaggggtatccgagggacagatgaagcaggtgctcccatcagcccagtgccatcctaccagcactctgacagagcgccctccttcctgctactggagacctgagacctgagggattctaggtggggaaaagtggcaatgtcccagcaggcaccacagtggatagcaccgtcacacacccgtctgagtttgacttttacctctgta

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