LOCUS       NR_174479               3672 bp    RNA     linear   ROD 07-AUG-2023
DEFINITION  Mus musculus RAS protein activator like 3 (Rasal3), transcript
            variant 6, non-coding RNA.
ACCESSION   NR_174479
VERSION     NR_174479.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3672)
  AUTHORS   Saito S, Cao DY, Victor AR, Peng Z, Wu HY and Okwan-Duodu D.
  TITLE     RASAL3 Is a Putative RasGAP Modulating Inflammatory Response by
            Neutrophils
  JOURNAL   Front Immunol 12, 744300 (2021)
   PUBMED   34777356
  REMARK    GeneRIF: RASAL3 Is a Putative RasGAP Modulating Inflammatory
            Response by Neutrophils.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3672)
  AUTHORS   Muro R, Nitta T, Kitajima M, Okada T and Suzuki H.
  TITLE     Rasal3-mediated T cell survival is essential for inflammatory
            responses
  JOURNAL   Biochem Biophys Res Commun 496 (1), 25-30 (2018)
   PUBMED   29291408
  REMARK    GeneRIF: Collectively, Rasal3 controls the magnitude of
            inflammatory responses through the survival of both naive T cells
            and activated T cells in vivo.
REFERENCE   3  (bases 1 to 3672)
  AUTHORS   Saito S, Kawamura T, Higuchi M, Kobayashi T, Yoshita-Takahashi M,
            Yamazaki M, Abe M, Sakimura K, Kanda Y, Kawamura H, Jiang S, Naito
            M, Yoshizaki T, Takahashi M and Fujii M.
  TITLE     RASAL3, a novel hematopoietic RasGAP protein, regulates the number
            and functions of NKT cells
  JOURNAL   Eur J Immunol 45 (5), 1512-1523 (2015)
   PUBMED   25652366
  REMARK    GeneRIF: results suggest that RASAL3 plays an important role in the
            expansion and functions of NKT cells in the liver by negatively
            regulating Ras/Erk signaling
REFERENCE   4  (bases 1 to 3672)
  AUTHORS   Muro R, Nitta T, Okada T, Ideta H, Tsubata T and Suzuki H.
  TITLE     The Ras GTPase-activating protein Rasal3 supports survival of naive
            T cells
  JOURNAL   PLoS One 10 (3), e0119898 (2015)
   PUBMED   25793935
  REMARK    GeneRIF: Rasal3 is required for in vivo survival of peripheral
            naive T cells, contributing to the maintenance of optimal T cell
            numbers.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3672)
  AUTHORS   Yu X, Bauer K, Koczan D, Thiesen HJ and Ibrahim SM.
  TITLE     Combining global genome and transcriptome approaches to identify
            the candidate genes of small-effect quantitative trait loci in
            collagen-induced arthritis
  JOURNAL   Arthritis Res Ther 9 (1), R3 (2007)
   PUBMED   17244351
REFERENCE   6  (bases 1 to 3672)
  AUTHORS   Okazaki N, Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga
            Y, Kitamura H, Nakagawa T, Nagase T, Ohara O and Koga H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT485616.11.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-526               CT485616.11        25328-25853         c
            527-666             CT485616.11        21562-21701         c
            667-745             CT485616.11        21357-21435         c
            746-807             CT485616.11        21189-21250         c
            808-875             CT485616.11        20293-20360         c
            876-1002            CT485616.11        19766-19892         c
            1003-1101           CT485616.11        19582-19680         c
            1102-1638           CT485616.11        18620-19156         c
            1639-1783           CT485616.11        18094-18238         c
            1784-1928           CT485616.11        17347-17491         c
            1929-2165           CT485616.11        16310-16546         c
            2166-2367           CT485616.11        16013-16214         c
            2368-2486           CT485616.11        15795-15913         c
            2487-2877           CT485616.11        14670-15060         c
            2878-3031           CT485616.11        14318-14471         c
            3032-3095           CT485616.11        13608-13671         c
            3096-3672           CT485616.11        12931-13507         c
FEATURES             Location/Qualifiers
     source          1..3672
                     /organism="Mus musculus"
                     /mol_type="transcribed RNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 17.55 cM"
     gene            1..3672
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /note="RAS protein activator like 3"
                     /db_xref="GeneID:320484"
                     /db_xref="MGI:MGI:2444128"
     misc_RNA        1..3672
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /product="RAS protein activator like 3, transcript variant
                     6"
                     /db_xref="GeneID:320484"
                     /db_xref="MGI:MGI:2444128"
     exon            1..526
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    133..2949
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="COORDINATES:
                     alignment:Blast2seq::RefSeq|NM_001400382.1"
                     /note="primary ORF has stop codon >50 nucleotides from the
                     terminal splice site; nonsense-mediated decay (NMD)
                     candidate"
     exon            527..666
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            667..745
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            746..807
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            808..875
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            876..1002
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1101
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1638
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1783
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1928
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1929..2165
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2166..2367
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..2486
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2487..2877
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2878..3031
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3032..3095
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3096..3672
                     /gene="Rasal3"
                     /gene_synonym="A430107D22Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gaggaaggaagctaggcacagtacagacggctgctggttctggactggccaggaaatcaaggtaagggagggtgtacgtgtggcatcctcaagtatgttcctggaggcgaagctgagaagagaccagggaagatgaagccagaatgtgggcagacaatgttcagaaccttttggtctcgcagcagagactcctccgccatggacccaccgttgcagagtgaagaagattcccaaacgcagccctcgctgccctctccgctgacatcctaccgctggcacactggaggcagtggggaaaaggctgctggagggttccgctggggccgctttgcaggctggggaagggccctgagccatcaggagcccatggtgaacagccagccagcccccagatctctgtttcgtcgggtcctctctgcaccccctaaggagtcacggtccaatcgcctccggttttccaagaccctgtggggaaggcacaagaacgtggcaccactggaacccaagccaaatccgaaggccccagagccagagctggagttggtagcagacccagatctacccgttgcacagatccctgagcctcccaccccggacatgcctgtttggaacattgatggctttacccttctcgaaggaaagctggtgatgctcggtgaggaggagggtcctcgccaaatccgagtgggaagcgccagttcagagaacagcatgcaggcagctttggggaacctcaaggatgcagttcggacccctggaaaaactgagccggaagctgctggttccaaccaggtccacaatgttcggttactcaagaggctgaaggagaagaaaagagccaagtcagaactgggagcctacacccctcgagatggacctcccagtgccctcggttccagagaatcgctggccacactctctgagctggacctaggtgctgagagggacgtgagagtctggccactgcatcctagcctcttgggggagccctactgcttccaggtaacctgggcaggtgggagcctctgtttctcatgtcgctcgagcgctgagagagaccgttggattgaggaccttcgtcggcagttccagccgagccaggacaacgtggagcggcaagagatgtggctgacggtgtgggtgcacgaggccaaagggctaccccgagcaactgtacccggagtgcgtgcggagctgtggttggatggcgcgctattggcgcgcactgccccccgtgccggcccaggccaactcttctgggctgaacgcttccacttcgaggcgttgccacctgcccgtcgcctgtcgctgcggttgcgcagcgcaggcccggcaggggcaaccgtgggcagggtggtgctggagctggacgaggtgagcatcccccgcgcgcctgccgcgggcctagagcgctggttcccggtgcttggggcgccggcaggtgcggtgctacgagcgcggatcagggtgcgttgtctgcgcgtgctgccgtcggagcgctataaggagctggccgagttcctcaccttccactacgcgcgcctgtgcggggcgctggagccggcgctgtctgctcaggccaaagaggagctggcagcagccatggtgcgcgtgctacgagccactggccgagcgcaggcattggtgacagacctaggaaccgcagagctggcacgctgtggaggccgtgaagcactgctattccgagaaaataccttagccacaaaggccattgatgaatacatgaaactggtggcacaggagtacctccaggacaccctggggcaggttgtgcggtgtctctgtgcctccactgaggactgtgaagtggaccccagcaagtgcccaacaccagagctgccaaaacaccaagctagactgcgagacagctgtgaggaggtttttgaaaacatcatccattcttacaactgtttcccagcagagctgggctccgtgttctcaagttggcgtgaagcatgcaaagcacgaggctctgaggccctgggcccccggctggtgtgtgcttccctcttcctgaggcttttatgccctgccatcttggcacctagcctctttggcctggcaccagagcacccagccccaggcccagccagaactcttacactcatcgccaaggtcatccagaacctcgccaactgtgccccgtttggtgagaaggaagcctacatggcgtttatgaatagcttcctggaagatcatggaccagccatgcaacacttcctggaccaggtagctacggtggatgcagataccacacccagtggctaccagggaagtggagacctggcccttcagttagcagttcttcatgtccagctctgcacaatctttgccgaacttgaccagaaaacccaagatagcttggaaccactacccaccatccttcgagccattgaggaaggccggcctgtcccagtgtctgtaccaatgcgtcttccccggatctccactcaggtccaatccagcttcttttcaggggagaaacccggcttcctggcaccccgagacctccccaagcacactcccctcatttccaagagtcaatctctgcgcagctttcaaggggcaggaagctgggccagtcggcggccagatgaggagcggccccagaggcggccgcggccagtgctgcgcacacagagcgtccctgccagacgtcctacccaccgtcgcccttctgcaggttccaagccgcggcccaaaggctccctacgcatgggccccgcgccttgcggacgggcctggactagggcttctgcctcgctacctcggaagccatcggtaccatggcagcgccaaatggaccagccgggggaccgataccaaactacgggaacgcaccgaccagtgggcaagcagagatacaatgtgaggtggctatattccgcgaggcacagaaagctctgtcccttctggtggagtcgttgagtacccaagtccaagccttgaaggagcagcaggagcacttccgctgtcagctgcaggatctgtactccagactgggagctggtatctcaaagttggattctaagggtggtctcccaagcaacggaagccacaggctgaaaagtctggaacagcgcctgactgagatggaatgttctcaggaccagctgagggatagcctccaaagcctgcaacttctttcaaaaacaccaggatctcggagccagcccctgcctctcaaagcaccatgtgtcaatggagctgatctgtcaatgggcacttgagcatttcaccccactccatatatggtctggaagccaagagagccactacagaggattttctgactgcctcagcccttcatggccttcagtgggggacagagtgggaggtgtcaatcactctggtaactgtgaggttgcccagtaaatccatttcagaaaatcaccggtttctctgcccctacaaatgattaatacaagagaatgcccagttctccattcaggtctcccaaattcatacctaatttgaagtctcctgaagttggaaataatgagcagatcctcacaattggtgtgatctaaggttgtcactttaagagactccattctctcctctgtaaagtgtatctaaaaattctccacatagtggaaaactcttagttaaaggtattcaataaagggtattgatcatttttggggggaa

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