LOCUS       NR_136937               1919 bp    RNA     linear   ROD 05-AUG-2023
DEFINITION  Mus musculus RNA binding motif protein 7 (Rbm7), transcript variant
            3, non-coding RNA.
ACCESSION   NR_136937
VERSION     NR_136937.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1919)
  AUTHORS   Fukushima K, Satoh T, Sugihara F, Sato Y, Okamoto T, Mitsui Y,
            Yoshio S, Li S, Nojima S, Motooka D, Nakamura S, Kida H, Standley
            DM, Morii E, Kanto T, Yanagita M, Matsuura Y, Nagasawa T, Kumanogoh
            A and Akira S.
  TITLE     Dysregulated Expression of the Nuclear Exosome Targeting Complex
            Component Rbm7 in Nonhematopoietic Cells Licenses the Development
            of Fibrosis
  JOURNAL   Immunity 52 (3), 542-556 (2020)
   PUBMED   32187520
REFERENCE   2  (bases 1 to 1919)
  AUTHORS   Tiedje C, Lubas M, Tehrani M, Menon MB, Ronkina N, Rousseau S,
            Cohen P, Kotlyarov A and Gaestel M.
  TITLE     p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human
            nuclear exosome targeting complex
  JOURNAL   RNA 21 (2), 262-278 (2015)
   PUBMED   25525152
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY087243.1, AK005998.1, AK153504.1 and AA178228.1.
            
            Transcript Variant: This variant (3) includes an alternate exon in
            the 5' coding region, compared to variant 1, which results in a
            frameshift and early stop codon. The transcript is sufficiently
            abundant to represent as a RefSeq record, however, the predicted
            protein is not represented because the product is significantly
            truncated and the transcript is a candidate for non-mediated mRNA
            decay (NMD).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005998.1, SRR7345562.788940.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                BY087243.1         2-26
            26-1423             AK005998.1         3-1400
            1424-1907           AK153504.1         1384-1867
            1908-1919           AA178228.1         456-467
FEATURES             Location/Qualifiers
     source          1..1919
                     /organism="Mus musculus"
                     /mol_type="transcribed RNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 26.43 cM"
     gene            1..1919
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /note="RNA binding motif protein 7"
                     /db_xref="GeneID:67010"
                     /db_xref="MGI:MGI:1914260"
     misc_RNA        1..1919
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /product="RNA binding motif protein 7, transcript variant
                     3"
                     /db_xref="GeneID:67010"
                     /db_xref="MGI:MGI:1914260"
     exon            1..176
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    81..200
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /inference="COORDINATES:
                     alignment:Blast2seq::RefSeq|NM_001326355.1"
                     /note="primary ORF has stop codon >50 nucleotides from the
                     terminal splice site; nonsense-mediated decay (NMD)
                     candidate"
     exon            177..281
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            282..444
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            445..532
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            533..627
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            628..1919
                     /gene="Rbm7"
                     /gene_synonym="1200007M24Rik; 1500011D06Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gtgagtgtttctgagggtgcgcagtagggtcggtcggccctgagcaggcagcctaggcctgggactggaacagcgcggagatgggggcggcggccgcagaggccgaccgcactctgttcgtgggtaacctggagacgaaggtgacagaggagctcctcttcgagctgttccaccagtatttgaggcagagagccatatagtatttcttggtagccctggaactccgaggctgacttagagctggtcctcctgcctgcatctcctgacatctgaccatacaggctgggccggtaataaaagtgaaaatcccgaaagataaagatggcaaactgaagcagtttgcattcgtgaacttcaaacatgaagtgtctgttccctatgccatgaatctgctcaacggaatcaaacttttcgggaggcctatcaaaattcagtttagatcaggaagcagtcacgcctctcaggatgccagtgtgtcatatccccagcatcatgttggaaatttaagcccaacctccacatctcctaacagctatgaaaggacagtgggtaacgtgtctccgacagctcagatggtccagaggtccttttcttctccagaagattatcagcggcaagcagtggtagatgaacagtgttttcagacagatgtcatatgctgggaaatttggttctccacatgcggatcagttgggattttcaccatcagctcaaccacatggccatacctttaaccagtcttccagctcccagtggcgccaagatgcactgtcatcacagcgtaaaagacagaattctcacccctacctagcagatagacactatagccgtgagcagcgctactctgaccatgggtctgactatcattacagaggcagccgagaggatttctactatgacgacaggaatcatgatggctggagccatgactatgataacagaagggacagtagtagaggtgggaagtggccctcatccagacactaacaagcattccaaggacactgtttacagggccattttaggtccttttaattaagttgttggagaaatatttctaaaagctgtacagagtaatcccacaattttccacctgtctttgaaaaaaattttttttaaacctagtaacagtttgacagaactgagaactgtggctccttgtgtgctactttaattacctaacctcaggggttctgaagaggaaggttcatacaagagtgtgtcaccatcccggccatgtcagacagtctcagaaagatgaaacggataggttggttgtattctaaagcaaatattttaagtatctcaccttttatgttgcaagaaatttcatggtaatgaatcaatttggtatatataataggaaacatctaagttggaagtctgaaatggctgtctgcattttgttaataaatgagaaaatagaacttttcagtcatctgcttattaatagtttatttaaaacagtttattggctttgtttggagataaatcatatttcctaactcagaatttaagtacaaattctgtggtatgctcttgaattttaccacaattgaacatacattataaatctttactagttcattctaagaactttaaaattctttcattatatttgatgtatgactagtcgctcaggaagttaaatatctcaatgtatatttttacacaaaatgacagtgttggtgaaaattcgttttagaatgatgttcatacatagagaaaatgacagtgtttgactgcaaggattgtaattttgaaattttgtttaacaaaacttccatgtttcaagatcctgttgctctttgactgcaaaactgtttctaagaattcattccatgaaaaatgtggatcctctttataccacagcatttatactatgttccttttaatatattaaatacacaaaaagagaa

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