LOCUS       NM_172733               1688 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus deoxyribose-phosphate aldolase (Dera), mRNA.
ACCESSION   NM_172733 XM_989396
VERSION     NM_172733.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1688)
  AUTHORS   Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J,
            Stein F, Schultz C, Sauer U and Aulehla A.
  TITLE     Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to
            Mouse Embryo Mesoderm Development
  JOURNAL   Dev Cell 40 (4), 331-341 (2017)
   PUBMED   28245920
REFERENCE   2  (bases 1 to 1688)
  AUTHORS   Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng
            EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC,
            Babbitt PC and Ferrin TE.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK083298.1.
            
            On May 4, 2006 this sequence version replaced XM_989396.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK083298.1, BC016218.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1688
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 67.32 cM"
     gene            1..1688
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /note="deoxyribose-phosphate aldolase"
                     /db_xref="GeneID:232449"
                     /db_xref="MGI:MGI:1913762"
     exon            1..62
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..988
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /EC_number="4.1.2.4"
                     /note="putative deoxyribose-phosphate aldolase;
                     deoxyriboaldolase; phosphodeoxyriboaldolase;
                     2-deoxy-D-ribose 5-phosphate aldolase;
                     2-deoxyribose-5-phosphate aldolase homolog;
                     deoxyribose-phosphate aldolase (putative)"
                     /codon_start=1
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="NP_766321.1"
                     /db_xref="CCDS:CCDS20666.1"
                     /db_xref="GeneID:232449"
                     /db_xref="MGI:MGI:1913762"
                     /translation="

MAAHCRGTELDLSWISKVQVNHAAVLRRAQQIQARRSVKKEWQAAWLLKAVTFIDLTTLSGDDTFSNVQRLCYKAKYPIRADLLKALNMDDKGITTAAVCVYPARVCDAVKALKAAGCSIPVASVATGFPAGQTHLKTRLEEIRLAVEDGATEIDVVINRTLVLTGQWEALYDEVTQFRKACGEAHLKTILATGELGSLTNVYKASLVAMMAGSDFIKTSTGKETVNATFPVAIVMLRAIRDFFWKTGNKVGFKPAGGIRTAKESLAWLSLVKEELGDEWLTPDLFRIGASSLLSDIERQIYHHVTGRYAAYHDLPMS"

     misc_feature    179..862
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /note="2-deoxyribose-5-phosphate aldolase (DERA) of the
                     DeoC family; Region: DeoC; cd00959"
                     /db_xref="CDD:188646"
     misc_feature    order(206..208,212..214,218..220,338..346,416..418,
                     440..442,455..457,470..481,506..508,512..514,569..574,
                     614..616)
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:188646"
     misc_feature    683..685
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188646"
     exon            63..160
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
     exon            161..308
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
     exon            309..404
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
     exon            405..539
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
     exon            540..668
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
     exon            669..781
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
     exon            782..931
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1688
                     /gene="Dera"
                     /gene_synonym="2010002D22Rik; 2500002K03Rik; DEOC"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gagcaagggttggctttcagcggtggccacaatggctgctcactgccggggcacagagctcgatcttagctggatctccaaagttcaagtgaatcacgcggctgtgctgaggcgggcccagcagatccaggctcgcagaagcgtgaagaaggaatggcaggctgcgtggctcctgaaagctgtcacgtttatagatcttaccacgctttctggcgatgacacgttttccaacgttcaacgactctgttataaagccaaatatccaatccgggcagacctcttaaaagctttaaatatggatgacaaaggcatcaccacagctgcagtctgcgtttatcccgcccgggtgtgcgacgctgtgaaggcgctgaaggctgcgggctgcagcatccccgtggcctcagtggccactggctttccagctggacagactcatttaaagactcgattggaagagatcagactggccgtggaggatggagctactgaaattgacgtggtcattaacaggaccttggtgctgacgggccagtgggaagctctctacgatgaggtcactcagtttcgaaaggcctgtggcgaggcccatctcaaaaccatcctagctacgggcgaactgggctctctcaccaacgtctacaaagccagcctggtagcgatgatggcaggatcagattttattaagacctctactggaaaggaaacagtaaacgccaccttcccagtcgccatcgtgatgctgcgggccattagagatttcttctggaaaactggaaacaaggtgggcttcaagcctgccggaggcatccgcactgcaaaggagtccctggcgtggctctccctggtcaaggaggaactaggagatgagtggctgacgcctgacctcttccggataggggccagttctctgctctcagacatcgagagacagatttaccatcacgtgactggacgctacgcggcttatcatgatcttccgatgtcttaggtcagcagccaacccagaaaagcatcttgcaacaaattgttcaaaaaaaaatgtttttgcataattgctaaggttatgtaattttggaacagctaactgactttccccattaaaatctcccctgaaatcaactcaaaacaataaagggaaacaaaccagctgaatctaaatgtggattcagatcaggaaaggttgaaatggtcttcgttaccaggaggtctacatttattaattttgtgaagattccctctgaaaaaaactcagaataaaatgtttctagtagcctgtactgcagaaaattctgaacgtacagtgaagttaagttgcctgagacctgagatcctagggcaggcagggctgtggagggaagggtgcttgctaccaaacctggcacacctgttcagctctgagcaaccacagggtggacggggagagccggctccaaaggctggcctctgacattcacacattcgtgtcccctacctctgacacataataaatacacttaaaactgtgataaaaatgagaatgggtgctatagcaagaggatactctgcccccctgtgctgcctaccaatgtggagccctgccccgggtgtccacctgactctctgtgctatactaaacatttagtaattgttttgctaatgagattgtgatgttgttgcaagaaaatgtggatatcgctgaatttttaaat

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