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Previous release (v1)
2024-11-01 09:35:20, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_144925 8493 bp mRNA linear ROD 26-JUN-2024
DEFINITION Mus musculus trinucleotide repeat containing 6a (Tnrc6a), mRNA.
ACCESSION NM_144925 XM_486002 XM_901687 XM_915472 XM_982893 XM_992542
VERSION NM_144925.3
KEYWORDS RefSeq; RefSeq Select.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 8493)
AUTHORS Liu,H., Li,H., Jiang,Z., Jin,S., Song,R., Yang,Y., Li,J., Huang,J.,
Zhang,X., Dong,X., Mori,M., Fritzler,M.J., He,L., Cardoso,W.V. and
Lu,J.
TITLE A local translation program regulates centriole amplification in
the airway epithelium
JOURNAL Sci Rep 13 (1), 7090 (2023)
PUBMED 37127654
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 8493)
AUTHORS Wei,W., Chen,Q., Liu,M., Sheng,Y., OuYang,Q., Feng,W., Yang,X.,
Ding,L., Su,S., Zhang,J., Fang,L., Vidal-Puig,A., Wang,H.Y. and
Chen,S.
TITLE TRIM24 is an insulin-responsive regulator of P-bodies
JOURNAL Nat Commun 13 (1), 3972 (2022)
PUBMED 35803934
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 8493)
AUTHORS Bedogni,F. and Hevner,R.F.
TITLE Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
Intermediate Progenitors Implicated in Axon Development
JOURNAL Front Mol Neurosci 14, 686034 (2021)
PUBMED 34321999
REMARK Publication Status: Online-Only
REFERENCE 4 (bases 1 to 8493)
AUTHORS Hildebrandt,M.R., Wang,Y., Li,L., Yasmin,L., Glubrecht,D.D. and
Godbout,R.
TITLE Cytoplasmic aggregation of DDX1 in developing embryos: Early
embryonic lethality associated with Ddx1 knockout
JOURNAL Dev Biol 455 (2), 420-433 (2019)
PUBMED 31330130
REFERENCE 5 (bases 1 to 8493)
AUTHORS Guo,H., Kazadaeva,Y., Ortega,F.E., Manjunath,N. and Desai,T.J.
TITLE Trinucleotide repeat containing 6c (TNRC6c) is essential for
microvascular maturation during distal airspace sacculation in the
developing lung
JOURNAL Dev Biol 430 (1), 214-223 (2017)
PUBMED 28811219
REFERENCE 6 (bases 1 to 8493)
AUTHORS McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
Silver,P.A.
TITLE A genome-wide in situ hybridization map of RNA-binding proteins
reveals anatomically restricted expression in the developing mouse
brain
JOURNAL BMC Dev Biol 5, 14 (2005)
PUBMED 16033648
REMARK Publication Status: Online-Only
REFERENCE 7 (bases 1 to 8493)
AUTHORS Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
Araki,M., Yamamura,K. and Araki,K.
TITLE Characterization of an exchangeable gene trap using pU-17 carrying
a stop codon-beta geo cassette
JOURNAL Dev Growth Differ 47 (3), 163-172 (2005)
PUBMED 15840001
REFERENCE 8 (bases 1 to 8493)
AUTHORS Yang,Z., Jakymiw,A., Wood,M.R., Eystathioy,T., Rubin,R.L.,
Fritzler,M.J. and Chan,E.K.
TITLE GW182 is critical for the stability of GW bodies expressed during
the cell cycle and cell proliferation
JOURNAL J Cell Sci 117 (Pt 23), 5567-5578 (2004)
PUBMED 15494374
REFERENCE 9 (bases 1 to 8493)
AUTHORS Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
TITLE BayGenomics: a resource of insertional mutations in mouse embryonic
stem cells
JOURNAL Nucleic Acids Res 31 (1), 278-281 (2003)
PUBMED 12520002
REFERENCE 10 (bases 1 to 8493)
AUTHORS Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
TITLE Exchangeable gene trap using the Cre/mutated lox system
JOURNAL Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
PUBMED 10512203
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BY720212.1, AK147327.1, CD802917.1, AC138364.8 and BF020619.1.
On or before Nov 2, 2006 this sequence version replaced
XM_486002.3, XM_915472.2, XM_901687.2, XM_992542.1, XM_982893.1,
NM_144925.2.
Summary: This gene encodes a member of the trinucleotide repeat
containing 6 protein family. The protein is highly similar to a
human protein that functions in post-transcriptional gene silencing
through the RNA interference (RNAi) and microRNA pathways. The
human protein associates with messenger RNAs and argonaute proteins
in cytoplasmic bodies known as GW-bodies or P-bodies, and
inhibiting its expression delocalizes other GW-body proteins and
impairs RNAi and microRNA-induced gene silencing. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK147327.1, SRR1660813.251091.1
[ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMN00849374, SAMN00849380
[ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on conservation, expression
##RefSeq-Attributes-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-296 BY720212.1 1-296
297-2202 AK147327.1 2-1907
2203-2784 CD802917.1 18-599
2785-5581 AK147327.1 2490-5286
5582-5582 AC138364.8 137287-137287 c
5583-7161 AK147327.1 5288-6866
7162-8031 AC138364.8 133970-134839 c
8032-8493 BF020619.1 1-462 c
FEATURES Location/Qualifiers
source 1..8493
/organism="Mus musculus"
/mol_type="mRNA"
/strain="C57BL/6"
/db_xref="taxon:10090"
/chromosome="7"
/map="7 67.42 cM"
gene 1..8493
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="trinucleotide repeat containing 6a"
/db_xref="GeneID:233833"
/db_xref="MGI:MGI:2385292"
exon 1..448
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
misc_feature 390..392
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="upstream in-frame stop codon"
CDS 444..6134
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="GW182 autoantigen"
/codon_start=1
/product="trinucleotide repeat-containing gene 6A protein"
/protein_id="NP_659174.3"
/db_xref="CCDS:CCDS57583.1"
/db_xref="GeneID:233833"
/db_xref="MGI:MGI:2385292"
/translation="
MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSDNGTSTATSTNNNAKRATASNQQPPPPQQQQPQQEQQQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSAVTNQQPQNNGEVQNSKSQSDINHNTSGSHYENCQRGPVSSTSDCSTSCKNAVNDLLEKEAWPSAPGSDPELAPECIDADSASNSESERNITVMASGNTGGEKDGLRNSTGLGSQSKFVVGSSSNNVGHGSSTGPWGFPHGALISTCQVSVDAPESKPESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQNINSKVSGSSTHGTWGSLQETCEPEVSGTQKVSFSGQPQNITTETTGPNNTTNFMTSSLPNSGSVQNNELPTSNPGAWRVSTMNHPQIQAPSVMNGTSLSHLSNGESKTGGSYGTTWGAYGSNYSGDKCAGPNGQANGDTVNATLMQPGINGPMGTNFQVNTNKGGGVWEPGTVNSQSSPWGSGNGANSGGSRRGWGSPAQNTGTGLSSVEWNKLPSNQHSNDSANGNGKKLTNGWKSTEEDDQGSATSQTNEQNSVWAKAGGTVESDGSAESTGRLEEKVTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACTDKTSPNSNDTSSVSGWGDPKPTLRWGDSKGSNCQGGWEDDSAATGMIKSNQWGGCKEDKSTWNDSQKSKQGWGDGQKSSQGWSISAGDNWGESSRSNHWGEANKKSSSGGSDSDRSISGWNELGKTSSFTWGNNINPNNSSGWDESSKPNSSQGWGDPPKCNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATSKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNIPEASGRSDQQAQMHRLLPAASAVSSKETSSGSGWGEPWAEPSTPATTVDNGTSAWGKPIDSGPSWGEPITAASNASTWGSSSVGPQSLSKSGPKSMQDGWCGDDMPLPGSRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEDAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMERNPYFDKNGNPNMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSAPSANRQQQDQQGRPLSVQQQMMQQSRQLDPSLLVKQQTPPSQQPLHQPAMKSFLDNVMPHTTPELQKGPSPVNAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSMSVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINSLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRVGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQSLGSSQSRLGSLDCSHSFSSRTDVNHWNGAGLSGANCGDLHGTSLWGTPHYSTSLWGPPSSDPRGISSPSPINAFLSVDHLGGGGESM"
misc_feature 444..3194
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Interaction with argonaute family proteins.
/evidence=ECO:0000250"
misc_feature 444..854
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 918..1070
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 1107..1193
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 1158..1907
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO1, AGO3 and
AGO4. /evidence=ECO:0000250"
misc_feature 1206..1436
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO2.
/evidence=ECO:0000250"
misc_feature 1212..1271
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 1350..1595
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO2.
/evidence=ECO:0000250"
misc_feature 1416..1715
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO2.
/evidence=ECO:0000250"
misc_feature <1611..>2477
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="serine-rich protein; Region: ser_rich_anae_1;
NF033849"
/db_xref="CDD:468206"
misc_feature 1623..1883
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO2.
/evidence=ECO:0000250"
misc_feature 1629..1826
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 1902..2651
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO2.
/evidence=ECO:0000250"
misc_feature 2085..2492
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 2094..4280
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO1 and AGO4.
/evidence=ECO:0000250"
misc_feature <2202..>3008
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="serine-rich protein; Region: ser_rich_anae_1;
NF033849"
/db_xref="CDD:468206"
misc_feature 2550..3437
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 2613..2615
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
misc_feature 3030..3032
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
misc_feature 3369..3371
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
misc_feature 3474..3821
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 3618..3830
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO2.
/evidence=ECO:0000250"
misc_feature 3621..4004
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Argonaute hook; Region: Ago_hook; pfam10427"
/db_xref="CDD:463088"
misc_feature 3870..3989
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 4032..4034
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
misc_feature 4143..4211
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 4206..4208
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
misc_feature <4236..4691
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="M domain of GW182; Region: M_domain; pfam12938"
/db_xref="CDD:432890"
misc_feature 4260..4361
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 4521..4628
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 4659..4661
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphothreonine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
misc_feature 4764..5549
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="TNRC6-PABC binding domain; Region: TNRC6-PABC_bdg;
pfam16608"
/db_xref="CDD:465195"
misc_feature 4977..5153
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 5001..5003
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
misc_feature 5256..6131
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Sufficient for interaction with AGO2.
/evidence=ECO:0000250"
misc_feature 5418..5498
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="propagated from UniProtKB/Swiss-Prot (Q3UHK8.2);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 5571..5846
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="RNA recognition motif (RRM) found in vertebrate
GW182 autoantigen; Region: RRM_TNRC6A; cd12711"
/db_xref="CDD:410110"
misc_feature 5853..5855
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
misc_feature 5916..5918
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q8NDV7; propagated from
UniProtKB/Swiss-Prot (Q3UHK8.2); phosphorylation site"
exon 449..496
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 497..584
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 585..606
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 607..990
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 991..3573
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 3574..3750
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 3751..3926
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 3927..3959
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 3960..4040
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 4041..4092
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 4093..4235
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 4236..4373
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 4374..4502
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 4503..4580
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 4581..4788
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 4789..4920
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 4921..5079
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 5080..5220
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 5221..5328
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 5329..5550
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 5551..5621
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 5622..5761
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
exon 5762..8479
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/inference="alignment:Splign:2.1.0"
regulatory 7721..7726
/regulatory_class="polyA_signal_sequence"
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="hexamer: AATAAA"
polyA_site 7754
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="major polyA site"
regulatory 8455..8460
/regulatory_class="polyA_signal_sequence"
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="hexamer: AATAAA"
polyA_site 8479
/gene="Tnrc6a"
/gene_synonym="2010321I05Rik; 3110054G10Rik; CAGH26;
D130023A07Rik; GW182; Tnrc6"
/note="major polyA site"
ORIGIN
gaaacttgtgtcgcagtaaagaaggaggaggggatggtccgaggcaagcccgagccagcctcggcgaaaaaggccgcgctccgctcttgccaggccccagagccgctcgtggggaacctcggagttccccgacagctccggcgaagtcctggacgcgtcagacagttgtcaagtggctgcctcgtccggcaggcctagttgctaggacctccatcttggggctcccgggccacggcgcccccggaaggggttgcgagtggggcattcacttccggtctggggcctgcggcggcagcggtggcggcggcggcggcggcggcagcgggacggtgtagaaaatggcgctggtgcagcggctcgggcctgtccccgcggcgctgcggagggcttgaggctcgcgagcctcgttccccgcgcctcacgcgctagtgcactttacacacatgagagaattggaagctaaagctaccaaagacgtagagagaaatcttagcagggatttagtgcaagaagaagaacagttgatggaagaaaagaaaaagaaaaaagacgacaagaaaaagaaggaagctgctcaaaagaaggccactgaacaaaaaatcaaagtgccagaacagataaagcccagtgtaagccagcctcagcctgccaactctgataacggcacttccacagcaaccagcactaataataatgccaagcgagctacagccagcaatcagcagccgccgccaccgcagcagcagcagccgcagcaagagcagcagcagcagcagccacaagccttgcctcggtatccacgtgaagtacctccacgatttcgccaccaggaacacaaacagcttctgaagaggggtcagcattttcctgtcatagcagcaaacttgggatctgctgttaaggtgttaaacagccaatcagaaagcagtgctgtaacaaatcaacagccacaaaataacggagaggtgcagaacagcaagagccagtcagatataaatcataatacttcaggatcccattatgaaaattgccagcggggacctgtgtcttctacaagtgactgtagcacaagctgtaagaatgctgtaaacgacttgttggaaaaagaagcatggccctcagcccctggcagtgatcctgagttggctccagaatgtatagatgctgattctgcctccaattctgagtcagagagaaacatcactgtcatggcttcagggaacacaggtggtgagaaagatggccttcggaacagcactggacttggttctcaaagcaaatttgtggttggtagcagcagcaataatgtgggccatggaagtagtactggcccatggggctttccccatggagccctaataagcacatgtcaggtctctgtggatgctcctgaaagcaaaccagaaagtagtaacaataggatgaatgcttggggcactgtaagttcttcatcaaatggagggttaaatccaagcactttgaattcagctagcaaccatggtgcctggccagtattagaaaacaatggacttgccctaaaagggcctgtagggagtgggagttctggcatcaatattcagtgtagtaccataggccagatgcctaacaatcagaatatcaactctaaagtcagtggctcttctacccatggtacctggggtagccttcaggaaacttgtgagcctgaagtaagtggtacacagaaggtttcattcagtggtcaacctcagaatatcaccactgaaacgactggaccaaataacactactaactttatgacctctagtttaccaaactccggttcagtacaaaataatgaactgcctactagtaatccaggggcctggcgtgtgagcacaatgaatcatcctcagatacaggctccgtcagttatgaatggcacttccctttctcaccttagtaatggagagtcaaaaactggaggctcctacggtactacatggggtgcctatggttctaattactctggcgacaaatgtgcaggccctaatggccaagccaatggtgacactgtgaatgcaactctaatgcagcctggcataaatgggcctatgggcactaactttcaagttaatacaaataaagggggaggtgtatgggagcctgggacagtgaattcccagagttcaccatggggaagtggaaatggtgcaaattctggaggaagtcgaagaggatggggaagtcctgcacagaacactggcactggtctatccagtgtcgagtggaacaaactgcctagcaaccagcattccaatgacagtgcaaatggcaatggtaagaagcttacaaatggatggaaatctactgaggaagacgatcagggttctgccacatctcagacaaatgagcaaaacagtgtgtgggccaaagcaggaggcacagtggagagtgatggtagtgcagagagcactggacgccttgaagaaaaagtaaccggggaaagtcagagtagagatagaagaaaaattgatcagcacacattactccaaagcattgtaaacagaactgacttagatccacgtgtcctatccaactctgggtggggacagactcctattaagcagaatactgcctgggatacagagacatcaccaagaggggaaagaaagactgacaatgggacagaggcctggggaagctctgcaacacagacttttaactcaggggcatgtacagataagactagccctaatagtaatgatacctcatctgtatcagggtggggtgatcccaaacctactctgaggtggggagattccaaaggctcaaactgccagggggggtgggaagatgactctgctgctacaggaatgatcaagagcaaccagtgggggggttgcaaggaagacaagtctacatggaatgattcgcaaaagagcaaacaaggctggggtgacggacaaaagtcaagccaaggttggtccatttctgccggtgataactggggagaatcttccaggagtaaccattggggtgaggccaataagaaatccagctcaggaggcagtgacagtgacaggtccatttctggttggaacgaacttgggaaaactagttcttttacttggggaaataatataaatccaaataactcatcgggatgggatgaatcttctaaaccgaactcttcccaggggtggggagaccctccaaagtgtaatcagtctctaggttggggagattcatcaaagccagttagttctccagattggaacaagcaacaagacattgttggatcatggggaatcccaccagccaccagcaagcctcctggtacaggctggctcgggggacctattcctgctccagcaaaggaggaagaacccacaggctgggaggagccatccccagaatctatacgaagaaaaatggagatcgatgatggaacttcagcttggggagatccaagcaaatacaactacaaaaatgtgaacatgtggaataaaaacatcccggaagccagcggccgctcagaccagcaagcgcagatgcaccggctattgccagccgcaagtgccgtctcaagcaaggagaccagcagtggctctggctggggtgagccttgggcagagccttctactccagccacaactgtggataatggtacttcagcctggggcaagcccatagacagtggtcccagctggggagaacccattactgcagcatccaatgcatccacgtggggctccagctctgttggtccacagtcattaagcaaatctgggcccaaatctatgcaagatggctggtgtggtgatgatatgccattgcctggaagtcgacccactggctgggaagaggaggaggatgtagagattggaatgtggaacagtaactcatctcaagagcttaactcatctttaaattggccaccatataccaagaaaatgtcatcaaagggtctgagtggcaaaaaaaggagaagggaaaggggaatgatgaaaggcggaaacaaacaagaggacgcatggataaatccattcgttaaacagttttcaaatatcagtttttcgagagactcaccagaagaaaatgtacagagcaataagatggatctttctggaggaatgttacaagacaagcggatggagattgataaacatagcctgaatattggtgattacaatcgaacggtcgggaaaggccctgggtctcggcctcagatttccaaagagtcttccatggagcgcaatccttactttgataagaatggcaatcccaatatgtttggtgttggaaacacagcagcacaaccccggggcatgcagcagcctccagcacaacctctcagttcatctcagcctaatcttcgtgctcaagtgcctcctccattactctcccctcaggttccagtttcattgctgaagtatgcaccaaacaacggtggcctgaatccgctctttggccctcaacaggtagccatgctgaaccagctatcccaactaaaccagctttctcagatctcccagttacagcgattgttagcgcagcagcagagggcacagagtcagagaagcgcgccttctgctaaccgacagcagcaggaccagcagggtcgacctcttagtgtgcagcagcagatgatgcaacagtctcgtcaacttgatccaagcctgctggtgaagcagcagactccgccttctcagcagccgctccatcagccagccatgaagtccttccttgacaatgtcatgccccacactacacccgagctgcagaaagggccatcgccagtaaatgctttcagcaactttcctataggcttgaactcaaacttgaatgtaaatatggatatgaacagtattaaagagccacagtcacgactaaggaagtggacaacagtggacagcatgtctgtgaacacgtcgttggatcagaactccagcaaacatggtgctatttcaagtggttttaggctggaagagtctccatttgttccctatgactttatgaatagcagtacttcaccagccagtcctccaggttcaataggagatggctggccacgtgccaaatcgcctaacggctctagcagtgttaactggccaccagaatttcgccctggtgaaccatggaaaggttatccaaacattgaccctgaaactgacccttacgtcactcctggcagtgtcataaacagtctttcaattaatactgtgcgggaagttgaccacctcagggacaggaacagtgggtcatcctcatccttgaacaccacgctgccttcaactagtgcctggtcatccattcgtgcctccaactacaatgttcccctcagcagtacagcacaaagcacttcagccagaaatagtgattccaaattgacgtggtctcctggttcagttacaaacacctctctggctcatgagctgtggaaagtccctttgccacctaaaaacatcactgctccgtcccgcccacctccggggctgactggtcagaagccacccttgtctacgtgggataattctccccttcgtgtaggtggaggatggggaaattctgatgccagatataccccaggctccagctggggtgagagcagctcagggagaataaccaattggcttgttctgaagaacctcacacctcagattgatggctcaactctgcgcaccctgtgcatgcagcatggcccactgattacattccatctgaacctcccacatggaaatgctctggtccgttacagttcaaaagaagaggtagtgaaggcacaaaagtctctgcacatgtgtgtgctggggaacactactattctcgctgagtttgccagtgaagaggagatcagtcgcttctttgcacaaagtcagtctctgaccccttctcctggctggcagtctctcgggtccagccagagccggctgggctctctcgactgttcccactcgttctccagccggactgatgtcaatcactggaatggtgctgggctgtcgggagctaactgtggagaccttcacggcacttccctctgggggaccccacattattccacaagcctgtggggtcccccgagcagcgacccccggggaattagcagcccatcccccattaatgcttttctttctgttgaccacctgggtgggggtggggagtccatgtaatggcataggtatagacgtaaactgtgacctcacgaagagaaggaaaggagcactaagttgggctcgccgcctgcagccagggcacctgtgggaacagctgttttctgcacattctccactttgttttccccaaaacatatcagtttgaatacttgaatcatgcaggccaatattataatgtgaaagggtatctatctatttacactcccaaacagcgccatacagctaccgtgtggaatgagctcacttgtgtattcatcatgtttagccttcggattccttctttcctccatttccatccccatccccaccttttatttttatttgtattttttgcaaaaccgttttggggctgacgtatgagcttttacctttgcactgagtgatgttctccgtctaatcggcaatatgggggcagctgttccagtgtagatgtttactcaagggtgttctcaaggcgtgcgctctctactatgcctcatgttgcctaccttagtgtggtatcgtggagttgaaaagatcaagttaagatactgacgtaggattcttaatgaaagtattgcaccagttttttcatgttgtaaaactaaagaatttcgctctacagtttgagaaactgtggccaccgctgtgacctgcagcccgcctgctgcccaggacgggccctgcactttgaacaggctttccatgttgttttgaaggttcccacggtgaaccttcttgtttacagatttttttgtttgttttttgagaaaaaaaatgtttactcttccatcatttaaaaaaaaaaaattaaaagacaaaaaaaaaaaaaaaggagggtggtttaaaagacgcttctatctctgggaaaagagcagcagttggccatgttcttctgttttctattcctgtcctaaatcaaagagcatggttctcaggaaaccagttccccggtcaaaaaatcttgtagtttcttataggaaagaagaaaacccaacttttagcactgatactacgtattgctctgttcaacattttctctgccaaaaaaagaaaaaaaaaaaaaaaagaaaagaaaaaagaaaaaaacgcgcttcgagctggagttgccgtctgctttcagatgctgtcctttagtagtgagtgatgatggtttgctaatcgctaggtgacttttgtaaccccatcagtggctctcatgtctctgctctcttgtgactgtgttcatgtttaactgttgtaccttaaagccgagatcagtaactatgcatactgtaaccaagacattgggcttacagagttgtttgttgtataaaaaattttaaatgttgttgcaaactaacgagttacaccattttaaaatttctttcctccctagcccctgttgttttgcccacaaatggtattataatgcttgcttagtcaaagagagactaaacaagggtaaacttttaacagtacagaatacgccatcatttcattgccttgattctaactgtttgtgtcctaagatgcaaaagaggtcagtggcttttaactgtttacaataggatgtgattgtaaatgtacagtttggttgtgtttgaattatgaaatcttcaaataataaaccatgactttttggctgctcaacattaattgtctcttttttgtggatttatttgtaggctcttttataatgaaagttacaaagttgctgcatgtgagagttcttctcatagagcggcagattaaaaatctaagcaaatatttgaacattttacctgaacttgtccacaatcaccctgagataatgtgagaacagtgggaactgtagcttgctcctcctcccctgagcatctgtgggagcttgttgttgcccaaagctcttctctggcttcaccttccccaccatctgtgcccatctcaagcctcagcgggaccattgggacacgaagctgactgccgtgacagcgtcctagtgttaacctctcatacctcacacagtggggatgccaccacctggactggcctctcttccctgtgcccttcgcccctcctcactgaaggagctctgggcacagaacctgtatgacttcaaatcacgctccacttgccaggtgtaagctaatgttggacaccgtaacctaagcaaatgtttaatgcattcggtgtgtgttgatgtccatactggtttttccaaaaaccaaaggtagctttgaaaaaccatgtgtggagatgtttggaccgttaagctgagtgaccgtttggggctttgagtagtatatatctgacttcatgacttcgttaattgtattgttaaaagtgtttgggagtttttttgcgcttgttatgtggaaataaagtgtttgatttaaaaaataaaaaaaaaaaaaaa
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]