LOCUS       NM_026632                655 bp    mRNA    linear   ROD 31-OCT-2023
DEFINITION  Mus musculus replication protein A3 (Rpa3), mRNA.
ACCESSION   NM_026632
VERSION     NM_026632.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 655)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 655)
  AUTHORS   McJunkin K, Mazurek A, Premsrirut PK, Zuber J, Dow LE, Simon J,
            Stillman B and Lowe SW.
  TITLE     Reversible suppression of an essential gene in adult mice using
            transgenic RNA interference
  JOURNAL   Proc Natl Acad Sci U S A 108 (17), 7113-7118 (2011)
   PUBMED   21482754
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY057686.1, AK009916.1 and BU757427.1.
            
            On Nov 15, 2008 this sequence version replaced NM_026632.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK625053.1, BQ746890.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                BY057686.1         2-32
            32-635              AK009916.1         4-607
            636-655             BU757427.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..655
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 3.53 cM"
     gene            1..655
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /note="replication protein A3"
                     /db_xref="GeneID:68240"
                     /db_xref="MGI:MGI:1915490"
     exon            1..142
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..409
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /note="RP-A p14; RF-A protein 3; replication factor A
                     protein 3"
                     /codon_start=1
                     /product="replication protein A 14 kDa subunit"
                     /protein_id="NP_080908.1"
                     /db_xref="CCDS:CCDS19909.1"
                     /db_xref="GeneID:68240"
                     /db_xref="MGI:MGI:1915490"
                     /translation="

MEDIMQLPKARVNASMLPQYIDRPVCFVGKLEKIHPTGKMFILSDGEGKNGTIELMEPLDEEISGIVEVVGKVTAKATVLCASYTLFKEDTNRFDLELYNEAVKIINELPQFFPVGLPQHE"

     misc_feature    56..382
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /note="Replication factor A protein 3; Region:
                     Rep_fac-A_3; pfam08661"
                     /db_xref="CDD:400821"
     misc_feature    order(65..70,74..76,245..247,305..307,323..328,344..346,
                     353..355,359..361,365..370,377..382)
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /note="trimerization core interface [active]"
                     /db_xref="CDD:239925"
     misc_feature    order(65..70,74..76,245..247,305..307,323..328,359..361,
                     368..370,377..382)
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /note="RPA3/RPA2 DBD-D interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239925"
     misc_feature    order(134..142,161..172,176..178,197..205,209..211,
                     236..238,257..265,275..283)
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /note="generic binding surface I [active]"
                     /db_xref="CDD:239925"
     misc_feature    order(326..328,344..346,365..367)
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /note="RPA3/RPA1 DBD-C interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239925"
     exon            143..217
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            218..326
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            327..638
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      620..625
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rpa3"
                     /gene_synonym="14kDa; C330026P08Rik"
                     /note="putative"
ORIGIN      

attttctgctttcctgcgggttgcgagtgttggcggcagaatcatggaggacataatgcagctccccaaagcgcgcgtcaacgccagcatgttaccacagtatatcgaccggcccgtgtgcttcgtggggaagctggaaaagattcatcccactggaaaaatgtttattctttcagatggagaaggaaaaaatggaaccattgaattgatggagccacttgacgaggaaatctctgggattgtagaagtagttggaaaagtcacagccaaggcgaccgtgctctgtgcatcttataccctgtttaaggaagatactaatcgctttgatcttgaactttacaatgaagctgtgaaaattatcaatgagcttcctcagtttttccctgtagggcttccacaacatgaatgagcttcttcagtttcttaagattgccaggaagctacactgaaggctattaaggaagactcctgcagtttaatggagcgactcctataatttctaatatttaatttgttcttttatatatatatatttttttgtaaatctattatgacagtttacaactaagcctttttataaactttttttaaaagtgatacttcaatatatagtctgaataataaaaatcaaaatatgaaaaaaaaaaaaaaaaaa

//