2024-11-01 08:13:57, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_023197 5073 bp mRNA linear ROD 12-JUN-2024 DEFINITION Mus musculus lysine rich nucleolar protein 1 (Knop1), transcript variant 1, mRNA. ACCESSION NM_023197 VERSION NM_023197.4 KEYWORDS RefSeq; RefSeq Select. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (bases 1 to 5073) AUTHORS Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A., Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R., Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J., Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z., Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J., Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L., Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J., Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B., Jackson,S.P. and Balmus,G. CONSRTM Sanger Mouse Genetics Project TITLE Genetic determinants of micronucleus formation in vivo JOURNAL Nature 627 (8002), 130-136 (2024) PUBMED 38355793 REFERENCE 2 (bases 1 to 5073) AUTHORS Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D., White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H., Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D., Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M., Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J., Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C., Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J., McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A., Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E., Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G., Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L., Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X., Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E., Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H., Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D., Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and Murray,S.A. CONSRTM International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center TITLE High-throughput discovery of novel developmental phenotypes JOURNAL Nature 537 (7621), 508-514 (2016) PUBMED 27626380 REMARK Erratum:[Nature. 2017 Nov 16;551(7680):398. doi: 10.1038/nature24643. PMID: 29144450] REFERENCE 3 (bases 1 to 5073) AUTHORS Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H., Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A., Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N., Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J., Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H., Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P., Skarnes,W.C., Mallon,A.M. and Parkinson,H. TITLE The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data JOURNAL Nucleic Acids Res 42 (Database issue), D802-D809 (2014) PUBMED 24194600 REFERENCE 4 (bases 1 to 5073) AUTHORS Valerius,M.T. and McMahon,A.P. TITLE Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation JOURNAL Gene Expr Patterns 8 (5), 297-306 (2008) PUBMED 18346943 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC138717.2 and AC165086.4. On Jan 14, 2022 this sequence version replaced NM_023197.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR7652917.362292.1, SRR9219382.154556.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-62 AC138717.2 105528-105589 c 63-1000 AC138717.2 102308-103245 c 1001-1069 AC138717.2 100526-100594 c 1070-1195 AC138717.2 98354-98479 c 1196-5073 AC165086.4 1524-5401 FEATURES Location/Qualifiers source 1..5073 /organism="Mus musculus" /mol_type="mRNA" /strain="C57BL/6" /db_xref="taxon:10090" /chromosome="7" /map="7 63.66 cM" gene 1..5073 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="lysine rich nucleolar protein 1" /db_xref="GeneID:66356" /db_xref="MGI:MGI:1913606" exon 1..62 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /inference="alignment:Splign:2.1.0" exon 63..1000 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /inference="alignment:Splign:2.1.0" CDS 65..1507 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="isoform 1 is encoded by transcript variant 1; protein C16orf88 homolog; testis-specific gene 118 protein" /codon_start=1 /product="lysine-rich nucleolar protein 1 isoform 1" /protein_id="NP_075686.3" /db_xref="CCDS:CCDS40104.1" /db_xref="GeneID:66356" /db_xref="MGI:MGI:1913606" /translation="
MVSKTQKADLGPQLPEKKKKKKKKKRVVANVSEPETQYSVLNSNDYFIDASPPRATSPSNNVDEVQIPEISLSKRKKKKKSCSTHLEECLGAEPTRARQKKSPSPRRQALEQSAEGLIREKKKKRRKSLSKAASQGSGLKTSPDPKHAKEVSKAGRKSKKQRKEKKVPDTEALPPQDAWLYEAGDSLHSCLEGAEAEEQAALGQKRKQGSPRDHNMKKKKKKTHQEGDILLVNSRVSVENSLKKGSKKSVKSEALEFVPIDSPKAPGKKKVKSKKKVEQPVGEGLAVKRKKKKKKKRKENGVKEDPWQEEKEESDTDLEVVLEKKGNMDETCIDQVRRKALQEEIDRESGKTEASEPKKWTVGLSVKTEASEPKKWTGTQFGQWDTAGFENEEQKLKFLKLMGGFKHLSPSFSRPPSMTIRSNMALDKKSSEMLQQSLQQDYDRAMSWKYSHGAGLGFNSEARKVFYIDRNASKSIKLQD"
misc_feature 215..217 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="Phosphoserine. /evidence=ECO:0000250|UniProtKB:Q1ED39; propagated from UniProtKB/Swiss-Prot (Q9Z2Q2.2); phosphorylation site" misc_feature 239..241 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="Phosphoserine. /evidence=ECO:0000250|UniProtKB:Q1ED39; propagated from UniProtKB/Swiss-Prot (Q9Z2Q2.2); phosphorylation site" misc_feature 488..490 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="Phosphoserine. /evidence=ECO:0000250|UniProtKB:Q1ED39; propagated from UniProtKB/Swiss-Prot (Q9Z2Q2.2); phosphorylation site" misc_feature 848..850 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="Phosphoserine. /evidence=ECO:0007744|PubMed:21183079; propagated from UniProtKB/Swiss-Prot (Q9Z2Q2.2); phosphorylation site" misc_feature 998..1504 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="propagated from UniProtKB/Swiss-Prot (Q9Z2Q2.2); Region: Interaction with ZNF106. /evidence=ECO:0000269|PubMed:15833274" misc_feature 1004..1006 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="Phosphoserine. /evidence=ECO:0007744|PubMed:21183079; propagated from UniProtKB/Swiss-Prot (Q9Z2Q2.2); phosphorylation site" misc_feature 1010..1012 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="Phosphothreonine. /evidence=ECO:0000250|UniProtKB:Q1ED39; propagated from UniProtKB/Swiss-Prot (Q9Z2Q2.2); phosphorylation site" misc_feature 1088..1204 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="propagated from UniProtKB/Swiss-Prot (Q9Z2Q2.2); Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" misc_feature 1214..1435 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="Small acidic protein family; Region: SMAP; pfam15477" /db_xref="CDD:464738" exon 1001..1069 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /inference="alignment:Splign:2.1.0" exon 1070..1195 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /inference="alignment:Splign:2.1.0" exon 1196..5073 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /inference="alignment:Splign:2.1.0" regulatory 1503..1508 /regulatory_class="polyA_signal_sequence" /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="hexamer: ATTAAA" polyA_site 1530 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="major polyA site" regulatory 1772..1777 /regulatory_class="polyA_signal_sequence" /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="hexamer: AATAAA" polyA_site 1790 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" regulatory 5048..5053 /regulatory_class="polyA_signal_sequence" /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="hexamer: AATAAA" polyA_site 5073 /gene="Knop1" /gene_synonym="2310008H09Rik; Tsg118" /note="major polyA site" ORIGIN
gacttccggatcgcggctgcgcggctgctcacgcggggacgcttggcctgctagcgaaccagtaatggtcagcaagacccagaaagcagacctgggcccacaactcccagagaagaagaaaaagaagaagaagaaaaagagagtggttgcaaatgtctcagaaccagagactcaatactcagtcttaaacagtaatgattattttatagacgcttctcctccgagggccacgtccccttctaacaatgtggatgaggtgcagatccccgagatatcactgagcaagagaaagaagaaaaaaaagtcctgtagcactcacttggaggagtgcctgggggctgagcctacacgggcaaggcagaaaaagtcacctagccctagaaggcaggcccttgagcagtcagcagaaggcctcatcagagagaagaaaaagaagaggcggaagtccttatcaaaggctgcctcccaaggctcagggctgaagacctccccagaccccaagcatgccaaggaggtaagcaaagctggtaggaagtccaaaaaacaaaggaaggaaaaaaaggttcctgacacggaagcccttcctccccaggacgcttggctctacgaggctggggattccctgcactcatgcttagagggggcagaggcagaggaacaggcagccttggggcagaaaaggaagcaggggagccccagagatcacaacatgaagaaaaagaagaagaagacccaccaggagggagacatcctcctggtcaactccagggtctctgtggagaacagcctgaagaaagggagtaagaagtcagtcaaaagtgaagctttggagttcgttccaatagacagcccgaaggcccctgggaagaagaaagtcaaatccaagaaaaaggtggaacagccagttggtgaagggctggctgtgaaaaggaagaagaagaagaagaagaagaggaaagagaacggagtaaaggaagacccctggcaggaggaaaaggaggagtcagacacagacttagaggtggtactggagaaaaaaggcaacatggatgagacctgcatagaccaggtgagacggaaggccttgcaagaagagattgatcgtgagtcgggcaagacagaggcttcagaacccaaaaagtggacagtgggtttgtcggtcaagacagaggcttcagaacccaaaaagtggacgggaacccagtttggccagtgggatactgccggctttgaaaatgaagaacagaagctaaaattcctgaagcttatgggtggctttaagcatctgtccccgtcattcagccgccctcccagcatgactatcaggtccaacatggccctggacaaaaagtcttcagaaatgctccagcagagtctgcagcaggactatgaccgggccatgagctggaagtacagccacggggctggcctgggctttaactctgaggcccgaaaggtcttctacattgaccggaatgcctccaagtctatcaagttgcaagattaaatattattgtcttgttcttcaaactgcatttcttgatcagttgcatccgtcaagttggcttgaaatagtcacctgcagttattgaggaccaataggaattgctaaagcctcctattttctatgttaaacattccacctccgggtgacagtattttaatagtagctagcagttgttggcacgtggagggtcctgactattttccttgcattgttacactaattatggaatgggtgctgttctcatctctatcaagttcagggataaataaagtaattaaacggcctagggtcaccttccgttaagtgccatcaagagtacatcacccagagtcactcaattatcagtgcagaaagcaagtgatatgccatgacttgcaagtttgttttccttctcccttatcaggaggcaggtgtggtgcagcaggcagacgtggccagtacctctgagctggcttctttccagccgtcctccttccatctgactgctgtgcttggatttgatgctgctgtattggctggatctcaaggcattttggacagtaggtaatcctgcgtatggacccatgacagattctcagcagcatgttttgtgtttgtgttcactagacagaagaccttggacacttgtgtgatgaaatcaaacatataaggggtggagaaaaagatactttgctgcaggcaccataccctcccacccctccctcccaaatcacagcaatcttcatggagctcctgatacagagacccatgtgacatgattttctctcccaccagctattggcagtctggtatcaaggttcagagaaggttactttcctgttttggcctgatttctcacaggcagaaacactgggtggggatggaggtgtttgatgctgcactcagccaggacattcattcatccttccagcaccgtcatcagtgttgatgccttcatgctgctaagaagatgagagacaattcccagcattccagagatgggagaaaaccctctctacaactaaagaaacttccggcagtccctcagggaacctgtgatggcgtcattcagctttgtagtttttcctgtatcagcccccttggtaaggagatgcccctcaggccagccagggagagggtgaggtgtgcagtactgccaaatgggcagcagaggtgttgctgtgccccctaccttgttcctgtcctgtgggcataggccatatgtatggcaaagacctgtttacaccactttcctggaatgaacttggcttctcatcaattcagcctcaagattcagaaaagaccacttccagtcacgtcaatggcagaattctgcatttgagtcaacttccagacaaatctccctcggccttggtgaactctgggaaccatctgcataactccaatagcttgtgttccccacaagtcacattccagcctaagtgtctcagctcatcaaaaacttgcacatggcaatcttacgggtggtagatggttttctatcttatgtcacatatgccttggaagctgtcatcaaagtgtgagagccagatctttttcttagctgttacacatacctcagtgctgaaagacttgattttgtagcttggtacctcagcgttgacttaggtgctccactagcccacctttctctaagaattgaagtctgtagtctatctccaaggcactggaggtagggtcagtgatctaacacaaccttgaacttgactgattctctcaggcatttcttaccagcttggtggcacttaagcaatatccttgtccaacagtcaccaaaatctcatgattcttaacacttgtgcttgagctgatttctgtgctatatctgcttgggcccatgaggccctgccctgaggctacatgtacaaccagactaacctgtgaaaaggctctctcagacacaggtgtccctgctcttagtactacttgggttatggtaggcaggacacacacatacccagcagaagggaaattaaagtcactaatcacatgctgctattattattgttgttgttgtttttttgagacagggtttctttgtgtagccctgaagaccataccatgctagccttaaaagtcacagcgattcacctgtctgcctcctggagtgctaggattaaaggtatacatcactgctgcctggcttccagccaccactggctatcagatagatttgaaatcagatccttgataacctgagcaggttcttttcttcacagttccctaactgatacgtagcagaagatttagtgtggaagacacttgggaaggaaaaggccacaagccaagatcacaggcaacgtacagaagccatgcagcatctctttccaccagagtacccacaaaagaacttagacatggggataccttgacctagcccagagaaaccagtgagttctgaccaacagcagtcaagacagtaaaaccacaggaagtcactgtgcttgtaatttcttaaaggaataagaaccaggaatcactcacagatggacatgaggcatcctgtttttcatttcctaaaagtctctttacatgtccttctcaggggaagtagatgctgtttgtggaggcgggcttcaaagactggactgtcagtaacacttctgcccaggtcagcagactgttgcaggagccccgtggtatgtgtacccagtgtgaggataagccgaggttaacacaagcagtgggaattccccaggccagtgtaagctgcttatgctgttatcctgggcagccttgaggcaggagagtaacgtacaaaggattatttatgaatttgccagttatttttgaaagaattagcatcacagtgaaagtgacataaaataattttagtagaaacagtttggtgaaataaaggccatttgggagtatttgaacagcaccatagtgcattctgggttctggcatgttcacagcaggaggaaaggcattttttagcatctggtttttgtttttgagactggggctcatatatcccagaccagcttcaaacatgtaactggggaccttgatcagatcttgatcctcctgtctctacctcctaactactgccgttctaggtctgcaccttggcactctgtcttatgtggggtcttgtgtctgccaggcaagcattccactgactgagccatatccttcgcctcatctgctcatttttggtttggtttttgttttaagaaattgtatcaattccttgggctggagggtattctcatcagattggccccaaatgtatatacaacagtaaccctgctctttgttgttgttgttttgttttgtttgttttttcgagacagggtttctctgtgtagccctgactgtcctggaactcactctgtagaccaacctgaccttgaactcagaaatccacctgcctctgcctctgcctcccaagtgctgggattaaaggcgtgcaccgccaccacctggctgtaactctgctcttaaactagtaaagacacaagctgtgtgtgtatgtgtgtgtgagacttaataacttctactttctgaggttagtcatgtatagtatttcagataaataaaatccatgcctaaagcacaaa
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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